Dendritic cell vaccines as cancer treatment: focus on 13 years of manufacturing and quality control experience in advanced therapy medicinal products

Authors: Granato, Anna Maria, Pancisi, Elena, Piccinini, Claudia, Stefanelli, Monica, Pignatta, Sara, Soldati, Valentina, Carloni, Silvia, Fanini, Francesca, Arienti, Chiara, Bulgarelli, Jenny, Tazzari, Marcella, Scarpi, Emanuela, Passardi, Alessandro, Tauceri, Francesca, La Barba, Giuliano, Maimone, Giuseppe, Baravelli, Stefano, de Rosa, Francesco, Ridolfi, Laura, Petrini, Massimiliano

Source: In Cytotherapy December 2024 26(12):1547-1555

First step results from a phase II study of a dendritic cell vaccine in glioblastoma patients (CombiG-vax).

Authors: Ridolfi, Laura, Gurrieri, Lorena, Riva, Nada, Bulgarelli, Jenny, De Rosa, Francesco, Guidoboni, Massimo, Fausti, Valentina, Ranallo, Nicoletta, Calpona, Sebastiano, Tazzari, Marcella, Petrini, Massimiliano, Granato, Anna Maria, Pancisi, Elena, Foca, Flavia, D'Allagata, Monia, Bondi, Isabella, Amadori, Elena, Cortesi, Pietro, Zani, Chiara, Ancarani, Valentina

Source: Frontiers in Immunology; 2024, p1-8, 8p

Subject Terms: CYTOTOXIC T cells, DENDRITIC cells, PROGRESSION-free survival, CELLULAR therapy, SKIN tests, LEUKAPHERESIS

Skewing effect of sulprostone on dendritic cell maturation compared with dinoprostone

Authors: Bulgarelli, Jenny ^*, Fiammenghi, Laura, Cassan, Serena, Granato, Anna Maria, Petrini, Massimiliano, Pancisi, Elena, Soldati, Valentina, De Rosa, Francesco, Ridolfi, Laura, Riccobon, Angela, Guidoboni, Massimo

Source: In Cytotherapy June 2018 20(6):851-860

Correction to: Comprehensive genomic profiling on metastatic Melanoma: results from a network screening from 7 Italian Cancer Centres.

Authors: Pallocca, Matteo, Molineris, Ivan, Berrino, Enrico, Marcozzi, Benedetta, Betti, Martina, Levati, Lauretta, D'Atri, Stefania, Menin, Chiara, Madonna, Gabriele, Ghiorzo, Paola, Bulgarelli, Jenny, Ferraresi, Virgina, Venesio, Tiziana, Rodolfo, Monica, Rivoltini, Licia, Lanfrancone, Luisa, Ascierto, Paolo Antonio, Mazzarella, Luca, Pelicci, Pier Giuseppe, De Maria, Ruggero

Source: Journal of Translational Medicine; 10/22/2024, Vol. 22 Issue 1, p1-3, 3p

Subject Terms: MOLECULAR oncology, MEDICAL specialties & specialists, LIFE sciences, INTERNAL medicine, CANCER genetics

Increased SHISA3 expression characterizes chronic lymphocytic leukemia patients sensitive to lenalidomide

Authors: Maffei, Rossana, Fiorcari, Stefania, Martinelli, Silvia, Benatti, Stefania, Bulgarelli, Jenny, Rizzotto, Lara, Debbia, Giulia, Santachiara, Rita, Rigolin, Gian Matteo, Forconi, Francesco, Rossi, Davide, Laurenti, Luca, Palumbo, Giuseppe A., Vallisa, Daniele, Cuneo, Antonio, Gaidano, Gianluca, Luppi, Mario, Marasca, Roberto

Source: Leukemia & lymphoma. 59(2):423-433

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100063152523.0x000001&indx=1&recIds=ETOCvdc_100063152523.0x000001

Comprehensive genomic profiling on metastatic Melanoma: results from a network screening from 7 Italian Cancer Centres.

Authors: Pallocca, Matteo, Molineris, Ivan, Berrino, Enrico, Marcozzi, Benedetta, Betti, Martina, Levati, Lauretta, D'Atri, Stefania, Menin, Chiara, Madonna, Gabriele, Ghiorzo, Paola, Bulgarelli, Jenny, Ferraresi, Virgina, Venesio, Tiziana, Rodolfo, Monica, Rivoltini, Licia, Lanfrancone, Luisa, Ascierto, Paolo Antonio, Mazzarella, Luca, Pelicci, Pier Giuseppe, De Maria, Ruggero

Source: Journal of Translational Medicine; 1/6/2024, Vol. 22 Issue 1, p1-7, 7p

Subject Terms: MACHINE learning, SINGLE nucleotide polymorphisms, MEDICAL screening, MELANOMA, RANDOM forest algorithms, PROGRESSION-free survival

Dendritic cell vaccination for metastatic melanoma: a 14-year monoinstitutional experience

Authors: de Rosa, Francesco, Ridolfi, Laura, Fiammenghi, Laura, Petrini, Massimiliano, Granato, Anna M., Ancarani, Valentina, Pancisi, Elena, Soldati, Valentina, Cassan, Serena, Bulgarelli, Jenny, Framarini, Massimo, Tauceri, Francesca, Migliori, Giuseppe, Brolli, Claudia, Gentili, Giorgia, Petracci, Elisabetta, Nanni, Oriana, Riccobon, Angela, Ridolfi, Ruggero, Guidoboni, Massimo

Source: Melanoma research. 27(4):351-357

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100046064849.0x000001&indx=1&recIds=ETOCvdc_100046064849.0x000001

Endothelium-mediated survival of leukemic cells and angiogenesis-related factors are affected by lenalidomide treatment in chronic lymphocytic leukemia

Authors: Maffei, Rossana, Fiorcari, Stefania, Bulgarelli, Jenny, Rizzotto, Lara, Martinelli, Silvia, Rigolin, Gian Matteo, Debbia, Giulia, Castelli, Ilaria, Bonacorsi, Goretta, Santachiara, Rita, Forconi, Francesco, Rossi, Davide, Laurenti, Luca, Palumbo, Giuseppe A., Vallisa, Daniele, Cuneo, Antonio, Gaidano, Gianluca, Luppi, Mario, Marasca, Roberto

Source: In Experimental Hematology February 2014 42(2):126-136

Immuno markers in newly diagnosed glioblastoma patients underwent Stupp protocol after neurosurgery: a retrospective series.

Authors: Gurrieri, Lorena, Mercatali, Laura, Ibrahim, Toni, Fausti, Valentina, Dall'Agata, Monia, Riva, Nada, Ranallo, Nicoletta, Pasini, Giuseppe, Tazzari, Marcella, Foca, Flavia, Bartolini, Daniela, Riccioni, Luca, Cavatorta, Chiara, Morigi, Federico Paolo, Bulgarelli, Jenny, Cocchi, Claudia, Ghini, Virginia, Tosatto, Luigino, Martinelli, Giovanni, Pession, Andrea

Source: Journal of Neuro-Oncology; Aug2023, Vol. 164 Issue 1, p55-64, 10p

ANGPT2 promoter methylation is strongly associated with gene expression and prognosis in chronic lymphocytic leukemia

Authors: Martinelli, Silvia, Kanduri, Meena, Maffei, Rossana, Fiorcari, Stefania, Bulgarelli, Jenny, Marasca, Roberto, Rosenquist, Richard

Source: Epigenetics. 8(7):720-729

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100050754280.0x000001&indx=1&recIds=ETOCvdc_100050754280.0x000001

Stability Program in Dendritic Cell Vaccines: A "Real-World" Experience in the Immuno-Gene Therapy Factory of Romagna Cancer Center.

Authors: Pancisi, Elena, Granato, Anna Maria, Scarpi, Emanuela, Ridolfi, Laura, Carloni, Silvia, Moretti, Cinzia, Guidoboni, Massimo, De Rosa, Francesco, Pignatta, Sara, Piccinini, Claudia, Soldati, Valentina, Calabrò, Luana, Framarini, Massimo, Stefanelli, Monica, Bulgarelli, Jenny, Tazzari, Marcella, Fanini, Francesca, Petrini, Massimiliano

Source: Vaccines; Jul2022, Vol. 10 Issue 7, pN.PAG-N.PAG, 11p

Subject Terms: DENDRITIC cells, CANCER vaccines, VACCINES, MEDICAL supplies, THERAPEUTICS

The Renewal of Cancer Immunotherapy.

Authors: Bulgarelli, Jenny, Pignatta, Sara, Petrini, Massimiliano, Ridolfi, Laura

Source: Vaccines; Mar2023, Vol. 11 Issue 3, p592, 3p

Subject Terms: IMMUNOTHERAPY, HEAD & neck cancer, IMMUNE checkpoint inhibitors, IMMUNOLOGIC memory

Radiotherapy and High-Dose Interleukin-2: Clinical and Immunological Results of a Proof of Principle Study in Metastatic Melanoma and Renal Cell Carcinoma.

Authors: Bulgarelli, Jenny, Piccinini, Claudia, Petracci, Elisabetta, Pancisi, Elena, Granato, Anna Maria, de Rosa, Francesco, Guidoboni, Massimo, Petrini, Massimiliano, Ancarani, Valentina, Foschi, Giovanni, Romeo, Antonino, Tontini, Luca, De Giorgi, Ugo, Lolli, Cristian, Gentili, Giorgia, Valmorri, Linda, Rossi, Alice, Ferroni, Fabio, Casadei, Carla, Cortesi, Pietro

Source: Frontiers in Immunology; 10/27/2021, Vol. 12, p1-14, 14p

Subject Terms: RENAL cell carcinoma, MELANOMA, INTERLEUKIN-2, PROOF of concept, RADIOTHERAPY, T cells, METASTASIS, SELF-monitoring (Psychology), PSYCHONEUROIMMUNOLOGY

Endothelin-1 Promotes Survival and Chemoresistance in Chronic Lymphocytic Leukemia B Cells through ETA Receptor.

Authors: Maffei, Rossana¹, Bulgarelli, Jenny¹, Fiorcari, Stefania¹, Martinelli, Silvia¹, Castelli, Ilaria¹, Valenti, Vanessa², Rossi, Davide³, Bonacorsi, Goretta¹, Zucchini, Patrizia¹, Potenza, Leonardo¹, Vallisa, Daniele², Gattei, Valter⁴, Poeta, Giovanni Del⁵, Forconi, Francesco^6,7, Gaidano, Gianluca³, Narni, Franco¹, Luppi, Mario¹, Marasca, Roberto¹ roberto.marasca@unimore.it

Source: PLoS ONE. Jun2014, Vol. 9 Issue 6, p1-13. 13p.

Subject Terms: *ENDOTHELIN receptors, *PROMOTERS (Genetics), *METASTASIS, *CHRONIC lymphocytic leukemia, *B cells, *CELLULAR signal transduction, *MITOGEN-activated protein kinases

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Dendritic Cell Vaccination in Metastatic Melanoma Turns "Non-T Cell Inflamed" Into "T-Cell Inflamed" Tumors.

Authors: Bulgarelli, Jenny, Tazzari, Marcella, Granato, Anna Maria, Ridolfi, Laura, Maiocchi, Serena, de Rosa, Francesco, Petrini, Massimiliano, Pancisi, Elena, Gentili, Giorgia, Vergani, Barbara, Piccinini, Filippo, Carbonaro, Antonella, Leone, Biagio Eugenio, Foschi, Giovanni, Ancarani, Valentina, Framarini, Massimo, Guidoboni, Massimo

Source: Frontiers in Immunology; 10/9/2019, p1-13, 13p

Subject Terms: DENDRITIC cells, CYTOTOXIC T cells, SUPPRESSOR cells, VACCINATION, T cells

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Results from the first step of a phase II study of vaccination with autologous dendritic cells loaded with autologous tumour homogenate in glioblastoma.

Authors: Ridolfi, Laura, Gurrieri, Lorena, Riva, Nada, Bulgarelli, Jenny, De Rosa, Francesco, Guidoboni, Massimo, Fausti, Valentina, Ranallo, Nicoletta, Tazzari, Marcella, Petrini, Massimiliano, Granato, Anna Maria, Pancisi, Elena, Foca, Flavia, Dall'Agata, Monia, Amadori, Elena, Cortesi, Pietro, Gamboni, Alessandro, Pasini, Giuseppe, Ibrahim, Toni, Tosatto, Luigino

Source: Journal of Clinical Oncology; 2023 Supplement 16, Vol. 41, pe14025-e14025, 1p

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