Overnutrition causes insulin resistance and metabolic disorder through increased sympathetic nervous system activity

Authors: Sakamoto, Kenichi ^{1, 2}, Butera, Mary A. ^{1, 2}, Zhou, Chunxue ², Maurizi, Giulia ², Chen, Bandy ^{1, 2}, Ling, Li ², Shawkat, Adham ¹, Patlolla, Likhitha ¹, Thakker, Kavira ¹, Calle, Victor ¹, Morgan, Donald A. ³, Rahmouni, Kamal ³, Schwartz, Gary J. ⁴, Tahiri, Azeddine ¹, Buettner, Christoph ^{1, 2, 5, ∗}

Source: In Cell Metabolism 7 January 2025 37(1):121-137

Why do some individuals with obesity remain metabolically healthy?

Authors: Buettner, Christoph ^{1, ⁎}, Sakamoto, Kenichi ¹, Butera, Mary A. ¹

Source: In Trends in Endocrinology & Metabolism January 2025 36(1):1-3

Sympathetic overdrive and unrestrained adipose lipolysis drive alcohol-induced hepatic steatosis in rodents

Authors: Zhou, Chunxue, Ruiz, Henry H., Ling, Li, Maurizi, Giulia, Sakamoto, Kenichi, Liberini, Claudia G., Wang, Ling, Stanley, Adrien, Egritag, Hale E., Sanz, Sofia M., Lindtner, Claudia, Butera, Mary A., Buettner, Christoph

Source: In Molecular Metabolism December 2023 78

Brain insulin signaling suppresses lipolysis in the absence of peripheral insulin receptors and requires the MAPK pathway

Authors: Metz, Matthäus, O'Hare, James, Cheng, Bob, Puchowicz, Michelle, Buettner, Christoph, Scherer, Thomas

Source: In Molecular Metabolism July 2023 73

Use of Patient-Reported Outcomes for Assessing Diabetes Outcomes

Authors: Kim, Hyon, Shah, Kunal, Buettner, Christoph

Source: In Endocrinology and Metabolism Clinics of North America December 2022 51(4):781-793

Tirzepatide for Congenital Generalized Lipodystrophy.

Authors: Ten, Svetlana¹, Bhangoo, Amrit², Buettner, Christoph¹, cb1116@rwjms.rutgers.edu

Source: New England Journal of Medicine; 2/13/2025, Vol. 392 Issue 7, p717-719, 3p

A 68 ka precipitation record from the hyperarid core of the Atacama Desert in northern Chile

Authors: Diederich, Julia L., Wennrich, Volker, Bao, Roberto, Büttner, Christoph, Bolten, Andreas, Brill, Dominik, Buske, Stefan, Campos, Eduardo, Fernández-Galego, Emma, Gödickmeier, Peggy, Ninnemann, Lukas, Reyers, Mark, Ritter, Benedikt, Ritterbach, Laura, Rolf, Christian, Scheidt, Stephanie, Dunai, Tibor J., Melles, Martin

Source: In Global and Planetary Change January 2020 184

Brain leptin reduces liver lipids by increasing hepatic triglyceride secretion and lowering lipogenesis

Authors: Hackl, Martina, Fürnsinn, Clemens, Schuh, Christina, Krssak, Martin, Carli, Fabrizia, Guerra, Sara, Freudenthaler, Angelika, Baumgartner-Parzer, Sabina, Helbich, Thomas, Luger, Anton, Zeyda, Maximilian, Gastaldelli, Amalia, Buettner, Christoph, Scherer, Thomas

Source: Nature communications. 10(1):1-13

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100181217821.0x000001&indx=1&recIds=ETOCvdc_100181217821.0x000001

Germline deletion of Krüppel-like factor 14 does not increase risk of diet induced metabolic syndrome in male C57BL/6 mice

Authors: Argmann, Carmen A., Violante, Sara, Dodatko, Tetyana, Amaro, Mariana P., Hagen, Jacob, Gillespie, Virginia L., Buettner, Christoph, Schadt, Eric E., Houten, Sander M.

Source: In BBA - Molecular Basis of Disease December 2017 1863(12):3277-3285

Selective Inhibition of FOXO1 Activator/Repressor Balance Modulates Hepatic Glucose Handling

Authors: Langlet, Fanny, Haeusler, Rebecca A., Lindén, Daniel, Ericson, Elke, Norris, Tyrrell, Johansson, Anders, Cook, Joshua R., Aizawa, Kumiko, Wang, Ling, Buettner, Christoph, Accili, Domenico

Source: In Cell 2 November 2017 171(4):824-835

Embryonic ablation of neuronal VGF increases energy expenditure and reduces body weight

Authors: Jiang, Cheng, Lin, Wei-Jye, Sadahiro, Masato, Shin, Andrew C., Buettner, Christoph, Salton, Stephen R.

Source: In Neuropeptides August 2017 64:75-83

IPSC-derived familial Alzheimer's PSEN2N141I cholinergic neurons exhibit mutation-dependent molecular pathology corrected by insulin signaling

Authors: Moreno, Cesar, Della Guardia, Lucio, Shnyder, Valeria, Ortiz-Virumbrales, Maitane, Kruglikov, Ilya, Zhang, Bin, Schadt, Eric, Tanzi, Rudolph, Noggle, Scott, Buettner, Christoph, Gandy, Sam

Source: Molecular neurodegeneration. 13(1):1-10

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171458673.0x000001&indx=1&recIds=ETOCvdc_100171458673.0x000001

Increased susceptibility to metabolic dysregulation in a mouse model of Alzheimer's disease is associated with impaired hypothalamic insulin signaling and elevated BCAA levels

Authors: Ruiz, Henry H., Chi, Tiffany, Shin, Andrew C., Lindtner, Claudia, Hsieh, Wilson, Ehrlich, Michelle, Gandy, Sam, Buettner, Christoph

Source: In Alzheimer's & Dementia: The Journal of the Alzheimer's Association August 2016 12(8):851-861

Optimal Connection of Heat Pump and Solar Buffer Storage under Different Boundary Conditions

Authors: Glembin, Jens, Büttner, Christoph, Steinweg, Jan, Rockendorf, Gunter

Source: In Energy Procedia June 2016 91:145-154

Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Attenuates Diabetes and Metabolic Disorders

Authors: Kang, Soojeong, Dahl, Russell, Hsieh, Wilson, Shin, Andrew, Zsebo, Krisztina M., Buettner, Christoph, Hajjar, Roger J., Lebeche, Djamel

Source: In Journal of Biological Chemistry 4 March 2016 291(10):5185-5198

Cholinergic neurons in the dorsomedial hypothalamus regulate mouse brown adipose tissue metabolism

Authors: Jeong, Jae Hoon, Lee, Dong Kun, Blouet, Clemence, Ruiz, Henry H., Buettner, Christoph, Chua, Streamson, Jr., Schwartz, Gary J., Jo, Young-Hwan

Source: In Molecular Metabolism June 2015 4(6):483-492

Thermal Storage Tanks in High Efficiency Heat Pump Systems – Optimized Installation and Operation Parameters

Authors: Glembin, Jens, Büttner, Christoph, Steinweg, Jan, Rockendorf, Gunter

Source: In Energy Procedia June 2015 73:331-340

Mitochondrial Shape Governs BAX-Induced Membrane Permeabilization and Apoptosis

Authors: Renault, Thibaud T., Floros, Konstantinos V., Elkholi, Rana, Corrigan, Kelly-Ann, Kushnareva, Yulia, Wieder, Shira Y., Lindtner, Claudia, Serasinghe, Madhavika N., Asciolla, James J., Buettner, Christoph, Newmeyer, Donald D., Chipuk, Jerry E.

Source: In Molecular Cell 8 January 2015 57(1):69-82

Brain Insulin Lowers Circulating BCAA Levels by Inducing Hepatic BCAA Catabolism

Authors: Shin, Andrew C., Fasshauer, Martin, Filatova, Nika, Grundell, Linus A., Zielinski, Elizabeth, Zhou, Jian-Ying, Scherer, Thomas, Lindtner, Claudia, White, Phillip J., Lapworth, Amanda L., Ilkayeva, Olga, Knippschild, Uwe, Wolf, Anna M., Scheja, Ludger, Grove, Kevin L., Smith, Richard D., Qian, Wei-Jun, Lynch, Christopher J., Newgard, Christopher B., Buettner, Christoph

Source: In Cell Metabolism 4 November 2014 20(5):898-909

Repurposing of bisphosphonates for the prevention and therapy of nonsmall cell lung and breast cancer

Authors: Stachnik, Agnes, Yuen, Tony, Iqbal, Jameel, Sgobba, Miriam, Gupta, Yogesh, Lu, Ping, Colaianni, Graziana, Ji, Yaoting, Zhu, Ling-Ling, Kim, Se-Min, Li, Jianhua, Liu, Peng, Izadmehr, Sudeh, Sangodkar, Jaya, Scherer, Thomas, Mujtaba, Shiraz, Galsky, Matthew, Gomez, Jorge, Epstein, Solomon, Buettner, Christoph, Bian, Zhuan, Zallone, Alberta, Aggarwal, Aneel K., Haider, Shozeb, New, Maria I., Sun, Li, Narla, Goutham, Zaidi, Mone

Source: Proceedings of the National Academy of Sciences of the United States of America, 2014 Dec . 111(50), 17995-18000.

Access URL: https://www.jstor.org/stable/43278821