Safety, tolerability, and efficacy of subcutaneous efgartigimod in patients with chronic inflammatory demyelinating polyradiculoneuropathy (ADHERE): a multicentre, randomised-withdrawal, double-blind, placebo-controlled, phase 2 trial

Authors: Grinzinger, Susanne, Wanschitz, Julia, Seifert-Held, Thomas, Claeys, Kristl G., Baets, Jonathan, Remiche, Gauthier, Bissay, Véronique, Dubuisson, Nicolas, Delstanche, Stephanie, Tarnev, Ivaylo, Genov, Krasimir, Tsvetanov, Plamen, Milanov, Ivan, Zhao, Chongbo, Bu, Bitao, Yu, Xuefan, Li, Wei, Jiang, Haishan, Da, Yuwei, Lu, Zuneng, Liang, Hui, Guo, Fuqiang, Li, Zunbo, Zou, Zhangyu, Hong, Daojun, Yang, Huan, Guo, Junhong, Shi, Jianquan, Tu, Jianglong, He, Dian, Wang, Yiqi, Ding, Jing, Zhang, Yali, Zhao, Yuanqi, Xu, Renxi, Yue, Yunhua, Guo, Aihong, Wang, Yuzhong, Talab, Radomir, Harbo, Thomas, Sindrup, Soeren, De Seze, Jérôme, Sacconi, Sabrina, Péréon, Yann, Echaniz-Laguna, Andoni, Magy, Laurent, Nicolas, Guillaume, Taithe, Frédéric, Cassereau, Julien, Debs, Rabab, Shakarishvili, Roman, Tsiskaridze, Alexander, Mania, Maka, Janelidze, Marina, Janelidze, Tamar, Schroeter, Michael, Skripuletz, Thomas, Lee, De-Hyung, Klehmet, Juliane, Hotter, Benjamin, Hoffmann, Olaf, Baum, Petra, Zschuentzsch, Jana, Pitarokoili, Kalliopi, Stettner, Mark, Bereczki, Dániel, Pánczél, Gyula, Abraham, Alon, Dori, Amir, Lampl, Yair, Manganelli, Fiore, Morino, Stefania, Padovani, Alessandro, Siciliano, Gabriele, Schenone, Angelo, Magri, Francesca, Mazzeo, Anna, Giannini, Fabio, Sorbi, Sandro, Chiò, Adriano, Kuwahara, Motoi, Okuno, Tatsusada, Okamoto, Tomoko, Kokubun, Norito, Nishiyama, Kazutoshi, Kaida, Kenichi, Bokuda, Kota, Katsuno, Masahisa, Yabe, Ichiro, Saji, Etsuji, Yokota, Takanori, Hatanaka, Yuki, Nakahara, Jin, Sugimoto, Takamichi, Tanaka, Fumiaki, Tomita, Satoshi, Yamano, Yoshihisa, Hayashi, Tomohiro, Yamazaki, Hiroki, Tokashiki, Takashi, Horiuchi, Kazuhiro, Karelis, Guntis, Eftimov, Filip, Banach, Marta, Chyrchel-Paszkiewicz, Urszula, Kochanowicz, Jan, Selmaj, Krzysztof, Zielinski, Tomasz, Banaszkiewicz, Krzysztof, Mitrea, Dan, Scutaru-Kadar, Ana-Maria, Axelerad, Any, Stuchevskaya, Fatima, Boyko, Alexey, Khabirov, Farit, Trushnikova, Tatiana, Goncharova, Zoya, Suponeva, Natalia, Dorogov, Nikolay, Yakupov, Eduard, Raicevic, Ranko, Miletic Drakulic, Svetlana, Cabrera Serrano, Macarena, Muñoz Blanco, Jose Luis, Guerrero Sola, Antonio, Aguera Morales, Eduardo, Diaz Marin, Carmen, Juntas Morales, Raúl, Yeh, Jiann-Horng, Sung, Jia-Ying, Huang, Han-Wei, Tsai, Nai-Wen, Guo, Yuh-Cherng, Chao, Chi-Chao, Ro, Long-Sun, Sengun, Ihsan, Terzi, Murat, Alpaydin Baslo, Sezin, Koç, Filiz, Necdet Karli, Hamdi, Shulga, Olga, Smolko, Dmytro, Doroshenko, Oleksandr, Tomakh, Nataliya, Kyrychenko, Alla, Seliuk, Olga, Kalbus, Oleksandr, Skrypchenko, Iryna, Novakovska, Olha, Carod-Artal, Francisco Javier, Rinaldi, Simon, Brennan, Kathryn, Ellis, Simon, Carr, Aisling, Matthews, Emma, Traub, Rebecca, Mozaffar, Tahseen, Elliott, Matthew, Bhavaraju-Sanka, Ratna, Nance, Christopher, Levine, Todd, Lisak, Robert, Pasnoor, Mamatha, Pulley, Michael, Roy, Bhaskar, Govindarajan, Raghav, Sahagian, Gregory, Khella, Sami, Jacob, Daniel, Kushlaf, Hani, Sivakumar, Kumaraswamy, Melamed, Isaac, Sharma, Khema, Quick, Adam, Ubogu, Eroboghene, Lacomis, David, Isa, Arnaldo, Brannagan, Thomas, Chen, Shan, Katz, Jonathan, Feinberg, Marc, Pavlakis, Pantelis, Lange, Dale, Gudesblatt, Mark, Tandan, Rup, Gable, Karissa, Rivner, Michael, Barnes, Benjamin, Luke, Donna, Mahuwala, Zabeen, Macwan, Samir, Kwon, Patrick, Scott, James, Altamimi, Sadiq, Sabharwal, Priyanka, Allen, Jeffrey A ^{a, *}, Lin, Jie ^b, Basta, Ivana ^c, Dysgaard, Tina ^d, Eggers, Christian ^e, Guptill, Jeffrey T ^{f, g}, Gwathmey, Kelly G ^h, Hewamadduma, Channa ^{i, j}, Hofman, Erik ^f, Hussain, Yessar M ^k, Kuwabara, Satoshi ^l, Le Masson, Gwendal ^m, Leypoldt, Frank ^{n, o}, Chang, Ting ^p, Lipowska, Marta ^{q, r}, Lowe, Murray ^f, Lauria, Giuseppe ^{s, t}, Querol, Luis ^{u, v}, Simu, Mihaela-Adriana ^w, Suresh, Niraja ^x, Tse, Anissa ^f, Ulrichts, Peter ^f, Van Hoorick, Benjamin ^f, Yamasaki, Ryo ^{y, z}, Lewis, Richard A ^{aa, *}, van Doorn, Pieter A ^{ab, *}

Source: In The Lancet Neurology October 2024 23(10):1013-1024

Therapeutic potential of natural killer cells in neuroimmunological diseases

Authors: Zhang, Qing, Lin, Jing, Yang, Mengge, Li, Zhijun, Zhang, Min, Bu, Bitao

Source: In Biomedicine & Pharmacotherapy April 2024 173

Clinical Features, Treatment, and Prognostic Factors of Childhood-Onset Myasthenia Gravis in a Large Chinese Cohort

Authors: Bi, Zhuajin, Ge, Huizhen, Zhang, Qing, Gao, Huajie, Yang, Mengge, Zhan, Jiayang, Lin, Jing, Gui, Mengcui, Li, Yue, Ji, Suqiong, Cao, Yayun, Bu, Bitao

Source: In Pediatric Neurology September 2023 146:31-39

The JAK1/3 Inhibitor Tofacitinib Regulates Th Cell Profiles and Humoral Immune Responses in Myasthenia Gravis.

Authors: Bi, Zhuajin, Zhang, Qing, Gao, Huajie, Ge, Huizhen, Zhan, Jiayang, Yang, Mengge, Bu, Bitao

Source: Muscle & Nerve; Mar2025, Vol. 71 Issue 3, p474-486, 13p

Modified models to distinguish central nervous system demyelinating diseases with brain lesions

Authors: Chen, Bo, Qin, Chuan, Ji, Suqiong, Tian, Daishi, Zhang, Min, Bu, Bitao

Source: In Multiple Sclerosis and Related Disorders July 2021 52

Safety of teriflunomide in Chinese adult patients with relapsing multiple sclerosis: A phase IV, 24-week multicenter study.

Authors: Quan, Chao, Zhou, Hongyu, Yang, Huan, Jiao, Zheng, Zhang, Meini, Zhang, Baorong, Tan, Guojun, Bu, Bitao, Jin, Tao, Li, Chunyang, Xue, Qun, Dong, Huiqing, Shi, Fudong, Qin, Xinyue, Zhang, Xinghu, Gao, Feng, Zhang, Hua, Wang, Jiawei, Hu, Xueqiang, Chen, Yueting

Source: Chinese Medical Journal; 2/20/2025, Vol. 138 Issue 4, p452-458, 7p

Long-term efficacy and safety of tacrolimus in anti-MuSK antibody-positive myasthenia gravis: a retrospective single-center cohort study.

Authors: Bi, Zhuajin, Li, Yue, Lin, Jing, Gui, Mengcui, Li, Zhijun, Bu, Bitao

Source: Neurological Sciences; Feb2025, Vol. 46 Issue 2, p943-949, 7p

Subject Terms: MYASTHENIA gravis, ANTIBODY titer, TACROLIMUS, DISEASE exacerbation, PATIENT safety

Amyloid myopathy mimicked with idiopathic inflammatory myopathy diagnosed using Congo red staining: a case report.

Authors: Han, Xingyu, Kosari, Mohammadreza, Xu, Li, Li, Yue, Yang, Meng-ge, Gao, Huajie, Ge, Huizhen, Bu, Bitao, Ji, Suqiong

Source: BMC Neurology; 11/27/2024, Vol. 24 Issue 1, p1-5, 5p

Subject Terms: CONGO red (Staining dye), CREATINE kinase, IDIOPATHIC diseases, BONE marrow, AMYLOID

Effect of thymectomy on the frequencies of peripheral regulatory B and T lymphocytes in patients with Myasthenia gravis-a pilot study.

Authors: Yu, Shanshan, Yan, Jingjun, Fang, Yu, Ye, Yan, Bu, Bitao

Source: International Journal of Neuroscience; Nov2024, Vol. 134 Issue 11, p1210-1219, 10p

Subject Terms: REGULATORY B cells, REGULATORY T cells, LYMPHOCYTE subsets, T cells, MYASTHENIA gravis

Retina as a potential biomarker for the early stage of Alzheimer's disease spectrum.

Authors: Gao, Rong, Luo, Huan, Yan, Su, Ba, Li, Peng, Sirui, Bu, Bitao, Sun, Xufang, Zhang, Min

Source: Annals of Clinical & Translational Neurology; Oct2024, Vol. 11 Issue 10, p2583-2596, 14p

Subject Terms: ALZHEIMER'S disease, OPTICAL coherence tomography, CEREBRAL circulation, NERVE fibers, COGNITIVE structures

Tacrolimus Improves Symptoms of Children With Myasthenia Gravis Refractory to Prednisone

Authors: Liu, Chanchan, Gui, Mengcui, Cao, Yayun, Lin, Jing, Li, Yue, Ji, Suqiong, Bu, Bitao ^*

Source: In Pediatric Neurology December 2017 77:42-47

Predictive Factors for Poor Outcomes Associated with COVID-19 in a Retrospective Cohort of Myasthenia Gravis Patients.

Authors: Bi, Zhuajin, Gao, Huajie, Lin, Jing, Gui, Mengcui, Li, Yue, Li, Zhijun, Bu, Bitao

Source: Journal of Inflammation Research; Aug2024, Vol. 17, p5807-5820, 14p

Subject Terms: REGULATORY T cells, COVID-19, SARS-CoV-2, OLDER patients, CHRONIC kidney failure, MYASTHENIA gravis

Effectiveness and safety of telitacicept for refractory generalized myasthenia gravis: a retrospective study.

Authors: Lin, Jing, Li, Yue, Gui, Mengcui, Bu, Bitao, Li, Zhijun

Source: Therapeutic Advances in Neurological Disorders; 5/14/2024, p1-13, 13p

Subject Terms: MYASTHENIA gravis, TALL-1 (Protein), B cells, IMMUNOPATHOLOGY, CLINICAL trials

Treatment algorithms of relapsing multiple sclerosis: an exploration based on the available disease-modifying therapies in China.

Authors: Guo, Jun, Wu, Jiayong, Wang, Lihua, Liu, Hongbo, Wu, Xiaomu, Yang, Huan, Li, Wenyu, Wang, Honghao, Bu, Bitao, Yang, Chunsheng, Zhou, Hongyu, Guo, Shougang, Zhao, Yinan, Wang, Zhanhang, Li, Chunyang, Tian, De-Cai, Chen, Sheng, Xue, Huiru, Zhang, Yanlin, Xu, Yongfeng

Source: Therapeutic Advances in Neurological Disorders; 4/13/2024, p1-19, 19p

Subject Terms: MULTIPLE sclerosis treatment, DISEASE relapse, DISEASE prevalence, CORTICOSTEROIDS, MEDICAL protocols

Batoclimab vs Placebo for Generalized Myasthenia Gravis: A Randomized Clinical Trial.

Authors: Yan, Chong, Yue, Yaoxian, Guan, Yuzhou, Bu, Bitao, Ke, Qing, Duan, Ruisheng, Deng, Hui, Xue, Qun, Jiang, Haishan, Xiao, Fei, Yang, Huan, Chang, Ting, Zou, Zhangyu, Li, Haifeng, Tan, Song, Xiao, Haibing, Zhou, Hongyu, Zhang, Hua, Meng, Qiang, Li, Wenyu

Source: JAMA Neurology; Apr2024, Vol. 81 Issue 4, p336-345, 10p

Role of diffusion tensor imaging or magnetic resonance spectroscopy in the diagnosis and disability assessment of amyotrophic lateral sclerosis

Authors: Liu, Chanchan, Jiang, Rifeng, Yi, Xiyan, Zhu, Wenzhen, Bu, Bitao

Source: In Journal of the Neurological Sciences 15 January 2015 348(1-2):206-210

Immunotherapy choice and maintenance for generalized myasthenia gravis in China.

Authors: Zhang, Chao^1,2,3 (AUTHOR), Bu, Bitao⁴ (AUTHOR), Yang, Huan⁵ (AUTHOR), Wang, Lihua⁶ (AUTHOR), Liu, Weibin⁷ (AUTHOR), Duan, Rui‐Sheng⁸ (AUTHOR), Zhang, Meini⁹ (AUTHOR), Zeng, Pei^2,3 (AUTHOR), Du, Chen^2,3 (AUTHOR), Yang, Li^2,3 (AUTHOR), Shi, Fu‐Dong^1,2,3 (AUTHOR) fshi@tmu.edu.cn

Source: CNS Neuroscience & Therapeutics. Dec2020, Vol. 26 Issue 12, p1241-1254. 14p.

Subject Terms: *MYASTHENIA gravis, *DISEASE relapse, *CORTICOSTEROIDS, *PROBABILITY measures, *DRUG efficacy, *IMMUNOTHERAPY

Geographic Terms: CHINA

TWEAK and Fn14 are overexpressed in immune-mediated necrotizing myopathy: implications for muscle damage and repair.

Authors: Yang, Mengge, Ge, Huizhen, Ji, Suqiong, Li, Yue, Xu, Li, Bi, Zhuajin, Bu, Bitao

Source: Rheumatology; Nov2023, Vol. 62 Issue 11, p3732-3741, 10p

Subject Terms: MUSCLE diseases, SKELETAL muscle, CONVALESCENCE, APOPTOSIS, GUIDED tissue regeneration, RESEARCH funding, DESCRIPTIVE statistics, MYOSITIS, STATISTICAL models, GAS gangrene

Novel variants and genotype-phenotype correlation in a multicentre cohort of GNE myopathy in China

Authors: Jiao, Kexin, Zhang, Jialong, Li, Qiuxiang, Lv, Xiaoqing, Yu, Yanyan, Zhu, Bochen, Zhong, Huahua, Yu, Xu’en, Song, Jia, Ke, Qing, Qian, Fangyuan, Luan, Xinghua, Zhang, Xiaojie, Chang, Xueli, Wang, Liang, Liu, Meirong, Dong, Jihong, Zou, Zhangyu, Bu, Bitao, Jiang, Haishan, Liu, LingChun, Li, Yue, Yue, Dongyue, Chang, Xuechun, Zheng, Yongsheng, Wang, Ningning, Gao, Mingshi, Xia, Xingyu, Cheng, Nachuan, Wang, Tao, Luo, Su-Shan, Xi, Jianying, Lin, Jie, Lu, Jiahong, Zhao, Chongbo, Yang, Huan, Lin, Pengfei, Hong, Daojun, Zhao, Zhe, Wang, Zhiqiang, Zhu, Wenhua

Source: Journal of Medical Genetics (JMG); 2024, Vol. 61 Issue: 11 p1053-1061, 9p

The effectiveness of teriflunomide in patients with multiple sclerosis in China: a real-world comparison to no DMT treatment in the first year after diagnosis.

Authors: Bu, Bitao, Quan, Chao, Li, Wenyu, Zeng, Qiuming, Shi, Ziyan, Chen, Bo, Zhou, Lei, Jin, Luya, Zhou, Hongyu, Yang, Huan

Source: Therapeutic Advances in Neurological Disorders; 7/24/2023, p1-15, 15p

Subject Terms: MULTIPLE sclerosis treatment, ANTI-inflammatory agents, CLINICAL trials, ACQUISITION of data

Geographic Terms: CHINA