Prospective REALITI-A Study: 2-Year Real-World Benefits of Mepolizumab in Severe Asthma

Authors: Caruso, Cristiano ^{a, ∗}, Canonica, G. Walter ^{b, c}, Patel, Manish ^d, Smith, Andrew ^d, Liu, Mark C. ^e, Alfonso-Cristancho, Rafael ^f, Price, Robert G. ^g, Jakes, Rupert W. ^h, Demetriou, Lydia ⁱ, Valero, Antonio ^j, Köhler, Thomas C. ^k, Pilette, Charles ^{l, m}, Chupp, Geoffrey ⁿ, Brusselle, Guy ^o, Howarth, Peter ^p

Source: In CHEST Pulmonary March 2025 3(1)

Augmenting clinical trials in asthma through digital technology, decentralised designs, and person-centric endpoints: opportunities and challenges

Authors: van Boven, Job F M ^{a, *}, Costello, Richard W ^b, Roes, Kit C B ^c, Brusselle, Guy G ^{d, e}, Hansen, Kjeld ^{f, g}, Krishnan, Jerry A ^h, Brightling, Christopher E ⁱ, Roche, Nicolas ^j, Siddiqui, Salman ^k, Kirenga, Bruce J ^l, Pinnock, Hilary ^m, Chan, Amy H Y ⁿ

Source: In The Lancet Respiratory Medicine February 2025 13(2):177-188

Dupilumab Induces Long-Term On-Treatment Clinical Remission in Patients With Type 2 Asthma

Authors: Pavord, Ian D. ^{a, ∗}, Rabe, Klaus F. ^b, Israel, Elliot ^{c, d}, Szefler, Stanley J. ^e, Brusselle, Guy ^f, Pandit-Abid, Nami ^g, Altincatal, Arman ^h, Chen, Zhen ⁱ, Amin, Nikhil ^{i, ∗}, Khan, Asif H. ^j, Lederer, David J. ⁱ, Zhang, Yi ⁱ, Rowe, Paul J. ^g, Deniz, Yamo ⁱ, Radwan, Amr ⁱ, Jacob-Nara, Juby A. ^g, Busse, William W. ^k

Source: In The Journal of Allergy and Clinical Immunology: In Practice January 2025 13(1):132-142

Run-in periods and treatment outcomes in asthma trials: A narrative review

Authors: Pizzichini, Emilio ^{a, b, 1, ⁎}, Brusselle, Guy ^c, Edwards, Dawn ^a, Gibson, Peter G. ^{d, e}, Kerstjens, Huib A. ^f, Moore, Alison ^a, Slade, David ^g, Wise, Robert A. ^h, Zhang, Shiyuan ⁱ

Source: In Contemporary Clinical Trials Communications December 2024 42

Exploring the genetics of airflow limitation in lung function across the lifespan – a polygenic risk score study

Authors: Hernandez-Pacheco, Natalia, Kilanowski, Anna, Kumar, Ashish, Curtin, John A., Olvera, Núria, Kress, Sara, Bertels, Xander, Lahousse, Lies, Bhatta, Laxmi, Granell, Raquel, Marí, Sergi, Bilbao, Jose Ramon, Sun, Yidan, Tingskov Pedersen, Casper-Emil, Karramass, Tarik, Thiering, Elisabeth, Dardani, Christina, Kebede Merid, Simon, Wang, Gang, Hallberg, Jenny, Koch, Sarah, Garcia-Aymerich, Judith, Esplugues, Ana, Torrent, Maties, Ibarluzea, Jesus, Lowe, Lesley, Simpson, Angela, Gehring, Ulrike, Vermeulen, Roel C.H., Roberts, Graham, Bergström, Anna, Vonk, Judith M., Felix, Janine F., Duijts, Liesbeth, Bønnelykke, Klaus, Timpson, Nic, Brusselle, Guy, Brumpton, Ben M., Langhammer, Arnulf, Turner, Stephen, Holloway, John W., Arshad, Syed Hasan, Ullah, Anhar, Custovic, Adnan, Cullinan, Paul, Murray, Clare S., van den Berge, Maarten, Kull, Inger, Schikowski, Tamara, Wedzicha, Jadwiga A., Koppelman, Gerard, Faner, Rosa, Agustí, Àlvar, Standl, Marie, Melén, Erik

Source: In eClinicalMedicine September 2024 75

Revisiting the Clinical Interpretation of CT-Measured Pulmonary Artery-to-Aorta Ratio—The Rotterdam Study

Authors: Khan, C.F., Kamran Ikram, M., Terzikhan, Natalie, Brusselle, Guy G., Bos, Daniel

Source: In Academic Radiology September 2024 31(9):3837-3843

Poor Rhinitis and Asthma Control Is Associated With Decreased Health-Related Quality of Life and Utilities: A MASK-air Study

Authors: Czarlewski, Wienczyslawa, Bedbrook, Anna, Haahtela, Tari, Canonica, G. Walter, Costa, Elisio M., Kupczyk, Maciej, Kvedariene, Violeta, Kulus, Marek, Larenas-Linnemann, Désirée E., Pfaar, Oliver, Papadopoulos, Nikolaos G., Pham-Thi, Nhân, Regateiro, Frederico S., Roche, Nicolas, Sastre, Joaquin, Scichilone, Nicola, Taborda-Barata, Luis, Valiulis, Arunas, Yorgancioglu, Arzu, Ventura, Maria Teresa, Almeida, Rute, Amaral, Rita, Ansotegui, Ignacio J., Bergmann, Karl C., Bosnic-Anticevich, Sinthia, Braido, Fulvio, Brussino, Luisa, Cardona, Victoria, Cecchi, Lorenzo, Loureiro, Claudia Chaves, Cingi, Cemal, Cruz, Alvaro A., Fokkens, Wytske J., de Vries, Govert, Gemicioglu, Bilun, Giuliana, Antonio F.M., Linuma, Tomohisa, Ivancevich, Juan Carlos, Jácome, Cristina, Kaidashev, Igor, Kraxner, Helga, Laune, Daniel, Louis, Gilles, Lourenço, Olga, Makela, Mika, Makris, Michael, Mösges, Ralph, Maurer, Marcus, Mullol, Joaquim, Nadif, Rachel, Niedoszytko, Marek, O’Hehir, Robyn, Okamoto, Yoshitaka, Ollert, Markus, Olze, Heidi, Patella, Vincenzo, Pétré, Benoit, Puggioni, Francesca, Romantowski, Jan, Rouadi, Philip W., Reitsma, Sietze, Rivero-Yeverino, Daniela, Rodriguez-Gonzalez, Monica, Sá-Sousa, Ana, Serpa, Faradiba S., Shamji, Mohamed H., Sheikh, Aziz, Ulrik, Charlotte Suppli, Sofiev, Mikhail, Sova, Milan, Sperl, Annette, Todo-Bom, Ana, Tomazic, Peter V., Toppila-Salmi, Sanna, Tsiligianni, Ioanna, Valovirta, Erkka, van Eerd, Michiel, Zidarn, Mihaela, Blain, Hubert, Boulet, Louis-Philippe, Brusselle, Guy, Buhl, Roland, Charpin, Denis, Casale, Thomas, Chivato, Tomas, Correia-de-Sousa, Jaime, Corrigan, Christopher, de Blay, Frédéric, Del Giacco, Stefano, Devillier, Philippe, Dykewicz, Mark, Fiocchi, Alessandro, Giovannini, Mattia, Jassem, Ewa, Jutel, Marek, Keil, Thomas, La Grutta, Stefania, Lipworth, Brian, Papi, Alberto, Pépin, Jean-Louis, Quirce, Santiago, Cordeiro, Carlos Robalo, Torres, Maria J., Usmani, Omar S., Vieira, Rafael José ^{a, b}, Leemann, Lucas ^c, Briggs, Andrew ^d, Pereira, Ana Margarida ^{a, b}, Savouré, Marine ^{e, f}, Kuna, Piotr ^g, Morais-Almeida, Mário ^h, Bewick, Michael ⁱ, Azevedo, Luís Filipe ^{a, b}, Louis, Renaud ^{j, k}, Klimek, Ludger ^{l, m}, Bahbah, Farah ⁿ, Samolinski, Boleslaw ^o, Anto, Josep M. ^{p, q, r}, Zuberbier, Torsten ^{s, t}, Fonseca, João A. ^{a, b}, Bousquet, Jean ^{s, t, u, ∗}, Sousa-Pinto, Bernardo ^{a, b}

Source: In The Journal of Allergy and Clinical Immunology: In Practice June 2024 12(6):1530-1538

Evaluating β2-agonists as siRNA delivery adjuvants for pulmonary surfactant-coated nanogel inhalation therapy

Authors: Merckx, Pieterjan, Conickx, Griet, Blomme, Evy, Maes, Tania, Bracke, Ken R., Brusselle, Guy, De Smedt, Stefaan C., Raemdonck, Koen

Source: In European Journal of Pharmaceutics and Biopharmaceutics April 2024 197

Exacerbation of cigarette smoke-induced pulmonary inflammation by Staphylococcus aureus Enterotoxin B in mice

Authors: Brusselle Guy G, Hellings Peter W, Demoor Tine, Bracke Ken R, Krysko Olga, Lanckacker Ellen A, Huvenne Wouter, Joos Guy F, Bachert Claus, Maes Tania

Source: Respiratory Research, Vol 12, Iss 1, p 69 (2011)

Subject Terms: Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: http://respiratory-research.com/content/12/1/69; https://doaj.org/toc/1465-9921

Access URL: https://doaj.org/article/adfd81e273584cbd87a8ca1d7500fa02

Biomarkers Associated with Lung Function Decline and Dupilumab Response in Patients with Asthma

Authors: Pavord, Ian D., De Prado Gómez, Lucia, Brusselle, Guy, Jackson, Daniel J., Brightling, Christopher E., Papi, Alberto, Maspero, Jorge F., Rabe, Klaus F., Korn, Stephanie, Zhang, Mei

Source: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 209(9):1031-1033

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN632811731&indx=1&recIds=ETOCRN632811731

Cigarette smoke induces PTX3 expression in pulmonary veins of mice in an IL-1 dependent manner

Authors: Mantovani Alberto, Garlanda Cecilia, Van Pottelberge Geert R, Maes Tania, Bracke Ken R, Pauwels Nele S, Joos Guy F, Brusselle Guy G

Source: Respiratory Research, Vol 11, Iss 1, p 134 (2010)

Subject Terms: Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: http://respiratory-research.com/content/11/1/134; https://doaj.org/toc/1465-9921

Access URL: https://doaj.org/article/d2282b78c8264ef1bddc9261fa4ed8ed

Different regulation of cigarette smoke induced inflammation in upper versus lower airways

Authors: Bracke Ken R, Robays Lander, Pauwels Nele, Maes Tania, Krysko Olga, De Ruyck Natalie, Derycke Lara, Pérez-Novo Claudina A, Huvenne Wouter, Joos Guy, Brusselle Guy, Bachert Claus

Source: Respiratory Research, Vol 11, Iss 1, p 100 (2010)

Subject Terms: Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: http://respiratory-research.com/content/11/1/100; https://doaj.org/toc/1465-9921

Access URL: https://doaj.org/article/330a3c56c3ab4bb7aba987294c369931

Selective accumulation of langerhans-type dendritic cells in small airways of patients with COPD

Authors: Vermassen Frank E, Verleden Geert M, van Drunen Cornelis M, Reinartz Susanne M, De Rijck Kim, Demedts Ingel K, Bracke Ken R, Van Pottelberge Geert R, Joos Guy F, Brusselle Guy G

Source: Respiratory Research, Vol 11, Iss 1, p 35 (2010)

Subject Terms: Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: http://respiratory-research.com/content/11/1/35; https://doaj.org/toc/1465-9921

Access URL: https://doaj.org/article/f615ea15b5ec4c3dab0fb05dd6391e3a

Role of the tachykinin NK1 receptor in a murine model of cigarette smoke-induced pulmonary inflammation

Authors: Brusselle Guy G, Demoor Tine, Bracke Ken R, De Swert Katelijne O, Joos Guy F

Source: Respiratory Research, Vol 10, Iss 1, p 37 (2009)

Subject Terms: Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: http://respiratory-research.com/content/10/1/37; https://doaj.org/toc/1465-9921

Access URL: https://doaj.org/article/da2c58c3b67b48ed9429468c2930679e

Cigarette smoke exposure facilitates allergic sensitization in mice

Authors: Brusselle Guy G, Maes Tania, Robays Lander J, Moerloose Katrien B, Tournoy Kurt G, Joos Guy F

Source: Respiratory Research, Vol 7, Iss 1, p 49 (2006)

Subject Terms: Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: http://respiratory-research.com/content/7/1/49; https://doaj.org/toc/1465-9921

Access URL: https://doaj.org/article/859c63eed83f4e2abf4d7c659d24f78f

Role of apoptosis in the pathogenesis of COPD and pulmonary emphysema

Authors: Joos Guy F, Bracke Ken R, Demoor Tine, Demedts Ingel K, Brusselle Guy G

Source: Respiratory Research, Vol 7, Iss 1, p 53 (2006)

Subject Terms: Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: http://respiratory-research.com/content/7/1/53; https://doaj.org/toc/1465-9921

Access URL: https://doaj.org/article/89efef820c2b435aad7a0f539b0d8f54

Cigarette smoke-induced pulmonary emphysema in scid-mice. Is the acquired immune system required?

Authors: Tournoy Kurt G, Demedts Ingel K, Bracke Ken R, Maes Tania, D'hulst An I, Joos Guy F, Brusselle Guy G

Source: Respiratory Research, Vol 6, Iss 1, p 147 (2005)

Subject Terms: Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: http://respiratory-research.com/content/6/1/147; https://doaj.org/toc/1465-9921

Access URL: https://doaj.org/article/e2fcad42a9a745578a474fc1c83de9f1

Serum immunoglobulin levels and risk of antibiotic prescription in middle-aged and older individuals: A population-based cohort study

Authors: Vanoverschelde, Anna, Khan, Samer R., Dalm, Virgil A.S.H., Chaker, Layal, Brusselle, Guy, Stricker, Bruno H., Lahousse, Lies

Source: In Clinical Immunology Communications 15 December 2023 4:23-29

Modelling ASthma TrEatment Responses (MASTER): Effect of individual patient characteristics on the risk of exacerbation in moderate or severe asthma: A time‐to‐event analysis of randomized clinical trials

Authors: Oosterholt, Sean, Pavord, Ian D., Brusselle, Guy, Yorgancıoğlu, Arzu, Pitrez, Paulo M., PG, Abhijith, Teli, Chirag, Della Pasqua, Oscar

Source: British journal of clinical pharmacology. 89(11):3273-3290

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196417660.0x000001&indx=1&recIds=ETOCvdc_100196417660.0x000001

MASK‐air® direct patient data support the ARIA‐MeDALL hypothesis on allergic phenotypes

Authors: Bousquet, Jean, Sousa‐Pinto, Bernardo, Regateiro, Frederico S., Pereira, Ana Margarida, Brussino, Luisa, Kvedariene, Violeta, Larenas‐Linnemann, Désirée E., Taborda‐Barata, Luis, Ventura, Maria Teresa, Vieira, Rafael José, Fonseca, Joao A., Zuberbier, Torsten, Anto, Josep M., Czarlewski, Wienczyslawa, Bedbrook, Anna, Haahtela, Tari, Klimek, Ludger, Pfaar, Oliver, Kuna, Piotr, Kupczyk, Maciej, Samolinski, Boleslaw, Valiulis, Arunas, Almeida, Rute, Jácome, Cristina, Yorgancioglu, Arzu, Bergmann, Karl‐Christian, Bosnic‐Anticevich, Sinthia, Canonica, G Walter, Cardona, Victoria, Cecchi, Lorenzo, Chaves Loureiro, Claudia, Cruz, Alvaro A, Gemicioglu, Bilun, Fokkens, Wytske J, Ivancevich, Juan Carlos, Kraxner, Helga, Laune, Daniel, Louis, Renaud, Makris, Michael, Morais‐Almeida, Mario, Mullol, Joaquim, Niedoszytko, Marek, Okamoto, Yoshitaka, Papadopoulos, Nikolaos G, Patella, Vincenzo, Pham‐Thi, Nhân, Rouadi, Philip W, Sastre, Joaquin, Scichilone, Nicola, Sheikh, Aziz, Sofiev, Mikhail, Toppila‐Salmi, Sanna, Tsiligianni, Ioanna, Valovirta, Erkka, Zidarn, Mihaela, Amaral, Rita, Ansotegui, Ignacio J, Boulet, Louis‐Philippe, Brusselle, Guy, Buhl, Roland, Charpin, Denis, Devillier, Philippe, Doyen, Virginie, Jassem, Ewa, Joos, Guy, Jutel, Marek, Keil, Thomas, Kulus, Marek, Lourenço, Olga, Mösges, Ralph, Nadif, Rachel, Nicola, Stefania, Papi, Alberto, Pépin, Jean‐Louis, Pétré, Benoit, Puggioni, Francesca, Quirce, Santiago, Reitsma, Sietze, Roche, Nicolas, Rodriguez‐Gonzalez, Monica, Sá‐Sousa, Ana, Savouré, Marine, Serpa, Faradiba S, Sova, Milan, Sperl, Annette, Usmani, Omar S, Tomazic, Peter Valentin, Vandenplas, Olivier

Source: Allergy. 78(10):2790-2794

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194504060.0x000001&indx=1&recIds=ETOCvdc_100194504060.0x000001