Post-Translational Variants of Major Proteins in Amyotrophic Lateral Sclerosis Provide New Insights into the Pathophysiology of the Disease.

Authors: Bedja-Iacona, Léa, Richard, Elodie, Marouillat, Sylviane, Brulard, Céline, Alouane, Tarek, Beltran, Stéphane, Andres, Christian R., Blasco, Hélène, Corcia, Philippe, Veyrat-Durebex, Charlotte, Vourc'h, Patrick

Source: International Journal of Molecular Sciences; Aug2024, Vol. 25 Issue 16, p8664, 20p

Subject Terms: AMYOTROPHIC lateral sclerosis, UBIQUITINATION, PATHOLOGICAL physiology, PHOSPHORYLATION, ACETYLATION, POST-translational modification

RNA sequencing validation of the Complexity INdex in SARComas prognostic signature

Authors: Lesluyes, Tom, Pérot, Gaëlle, Largeau, Marine Roxane, Brulard, Céline, Lagarde, Pauline, Dapremont, Valérie, Lucchesi, Carlo, Neuville, Agnès, Terrier, Philippe, Vince-Ranchère, Dominique, Mendez-Lago, Maria, Gut, Marta, Gut, Ivo, Coindre, Jean-Michel, Chibon, Frédéric

Source: In European Journal of Cancer April 2016 57:104-111

Genes containing hexanucleotide repeats resembling C9ORF72 and expressed in the central nervous system are frequent in the human genome

Authors: Vourc’h, Patrick, Wurmser, François, Brulard, Céline, Mouzat, Kevin, Kassem, Sandra, Dangoumau, Audrey, Laumonnier, Frédéric, Blasco, Hélène, Corcia, Philippe, Andres, Christian R.

Source: In Neurobiology of Aging January 2021 97:148-148

Uterine smooth muscle tumor analysis by comparative genomic hybridization: a useful diagnostic tool in challenging lesions

Authors: Croce, Sabrina, Ribeiro, Agnes, Brulard, Celine, Noel, Jean-Christophe, Amant, Frederic, Stoeckle, Eberhard, Devouassoux-Shisheborah, Mojgan, Floquet, Anne, Arnould, Laurent, Guyon, Frederic, Mishellany, Florence, Garbay, Delphine, Cuppens, Tine, Zikan, Michal, Leroux, Agnès, Frouin, Eric, Duvillard, Pierre, Terrier, Philippe, Farre, Isabelle, Valo, Isabelle, MacGrogan, Gaetan M, Chibon, Frederic

Source: In Modern Pathology July 2015 28(7):1001-1010

Genes containing hexanucleotide repeats resembling C9ORF72 and expressed in the central nervous system are frequent in the human genome

Authors: Vourc'h, Patrick, Wurmser, François, Brulard, Céline, Mouzat, Kevin, Kassem, Sandra, Dangoumau, Audrey, Laumonnier, Frédéric, Blasco, Hélène, Corcia, Philippe, Andres, Christian R.

Source: NEUROBIOLOGY OF AGING. 97:148.e1-148.e7

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100116520651.0x000001&indx=1&recIds=ETOCvdc_100116520651.0x000001

Genomic index predicts clinical outcome of intermediate-risk gastrointestinal stromal tumours, providing a new inclusion criterion for imatinib adjuvant therapy

Authors: Lartigue, Lydia, Neuville, Agnès, Lagarde, Pauline, Brulard, Céline, Rutkowski, Piotr, Tos, Paolo Dei, Wardelmann, Eva, Debiec-Rychter, Maria, Italiano, Antoine, Coindre, Jean-Michel, Chibon, Frédéric

Source: In European Journal of Cancer January 2015 51(1):75-83

Mutation in the RRM2 domain of TDP-43 in Amyotrophic Lateral Sclerosis with rapid progression associated with ubiquitin positive aggregates in cultured motor neurons

Authors: Maurel, Cindy, Madji-Hounoum, Blandine, Thepault, Rose-Anne, Marouillat, Sylviane, Brulard, Céline, Danel-Brunaud, Véronique, Camdessanche, Jean-Philippe, Blasco, Helene, Corcia, Philippe, Andres, Christian R., Vourc'h, Patrick

Source: Amyotrophic lateral sclerosis and frontotemporal degeneration. 19(1-2):149-151

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100063119845.0x000001&indx=1&recIds=ETOCvdc_100063119845.0x000001

A novel mutation in the transmembrane 6 domain of GABBR2 leads to a Rett‐like phenotype

Authors: Vuillaume, Marie‐Laure, Jeanne, Médéric, Xue, Li, Blesson, Sophie, Denommé‐Pichon, Anne‐Sophie, Alirol, Servane, Brulard, Céline, Colin, Estelle, Isidor, Bertrand, Gilbert‐Dussardier, Brigitte, Odent, Sylvie, Parent, Philippe, Donnart, Audrey, Redon, Richard, Bézieau, Stéphane, Rondard, Philippe, Laumonnier, Frédéric, Toutain, Annick

Source: Annals of neurology. 83(2):437-439

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100081731271.0x000001&indx=1&recIds=ETOCvdc_100081731271.0x000001

Study of Ubiquitin Pathway Genes in a French Population with Amyotrophic Lateral Sclerosis: Focus on HECW1 Encoding the E3 Ligase NEDL1.

Authors: Haouari, Shanez, Andres, Christian Robert, Lanznaster, Debora, Marouillat, Sylviane, Brulard, Céline, Dangoumau, Audrey, Ung, Devina, Veyrat-Durebex, Charlotte, Laumonnier, Frédéric, Blasco, Hélène, Couratier, Philippe, Corcia, Philippe, Vourc'h, Patrick

Source: International Journal of Molecular Sciences; Jan2023, Vol. 24 Issue 2, p1268, 13p

Subject Terms: UBIQUITIN ligases, AMYOTROPHIC lateral sclerosis, UBIQUITIN, FRENCH people, GENES, NUCLEOTIDE sequencing, MOTOR neurons

A high-risk retinoblastoma subtype with stemness features, dedifferentiated cone states and neuronal/ganglion cell gene expression.

Authors: Liu, Jing, Ottaviani, Daniela, Sefta, Meriem, Desbrousses, Céline, Chapeaublanc, Elodie, Aschero, Rosario, Sirab, Nanor, Lubieniecki, Fabiana, Lamas, Gabriela, Tonon, Laurie, Dehainault, Catherine, Hua, Clément, Fréneaux, Paul, Reichman, Sacha, Karboul, Narjesse, Biton, Anne, Mirabal-Ortega, Liliana, Larcher, Magalie, Brulard, Céline, Arrufat, Sandrine

Source: Nature Communications; 9/22/2021, Vol. 12 Issue 1, p1-20, 20p

Subject Terms: INTERFERON gamma, CONES, RETINOBLASTOMA, GENE expression, GANGLIA

Robust gene expression signature is not merely a significant P value

Authors: Brulard, Céline, Chibon, Frédéric

Source: In European Journal of Cancer August 2013 49(12):2771-2773

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RCBTB1 Deletion Is Associated with Metastatic Outcome and Contributes to Docetaxel Resistance in Nontranslocation-Related Pleomorphic Sarcomas.

Authors: Mauduit, Olivier^1,2,3 (AUTHOR) olivier.mauduit@live.fr, Brulard, Céline^1,3 (AUTHOR) celine.brulard@univ-tours.fr, Lesluyes, Tom^1,4 (AUTHOR) tom.lesluyes@inserm.fr, Delcroix, Vanessa^1,4 (AUTHOR) vanessa.delcroix@orange.fr, Pérot, Gaëlle^1,3 (AUTHOR) gaelle.perot@inserm.fr, Choublier, Nina^1,5 (AUTHOR) nina.choublier@inserm.fr, Michaud, Mickael^1,3 (AUTHOR) mickael_michaud@yahoo.fr, Baud, Jessica^1,3 (AUTHOR) j.massiere@bordeaux.unicancer.fr, Lagarde, Pauline¹ (AUTHOR) pauline.lagarde@wanadoo.fr, Aurias, Alain¹ (AUTHOR) alain.aurias@hotmail.fr, Coindre, Jean-Michel^1,3,4 (AUTHOR) J.Coindre@bordeaux.unicancer.fr, Lartigue, Lydia^1,4 (AUTHOR) lydia.lartigue@gmail.com, Blay, Jean-Yves⁶ (AUTHOR) jean-yves.blay@lyon.unicancer.fr, Chibon, Frédéric^1,3,7 (AUTHOR) Frederic.chibon@inserm.fr

Source: Cancers. Jan2019, Vol. 11 Issue 1, p81. 1p.

Subject Terms: *SARCOMA, *CELL proliferation, *APOPTOSIS, *CANCER chemotherapy, *CELL lines, *CELLULAR signal transduction, *DRUG resistance in cancer cells, *GENE expression, *LONGITUDINAL method, *GENETIC mutation, *XENOGRAFTS, *DOCETAXEL, *GENOMICS, *RETROSPECTIVE studies, *LEIOMYOSARCOMA, *IN vitro studies, *IN vivo studies, *GENETICS, RISK of metastasis

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Dysregulations of Expression of Genes of the Ubiquitin/SUMO Pathways in an In Vitro Model of Amyotrophic Lateral Sclerosis Combining Oxidative Stress and SOD1 Gene Mutation.

Authors: Dangoumau, Audrey, Marouillat, Sylviane, Coelho, Roxane, Wurmser, François, Brulard, Céline, Haouari, Shanez, Laumonnier, Frédéric, Corcia, Philippe, Andres, Christian R., Blasco, Hélène, Vourc'h, Patrick, Poletti, Angelo

Source: International Journal of Molecular Sciences; Feb2021, Vol. 22 Issue 4, p1796-1796, 1p

Subject Terms: AMYOTROPHIC lateral sclerosis, GENETIC mutation, OXIDATIVE stress, UBIQUITIN, GENE expression, MOTOR neurons

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