Childhood Langerhans cell histiocytosis hematological involvement: severity associated with BRAFV600E loads

Authors: Devoldere, Catherine, Gourmel, Antoine, Lutun, Anne, Leglise, Sophie, Pellier, Isabelle, Proust, Stéphanie, Cheikh, Nathalie, Klein, Sébastien, Simon, Pauline, Verite, Cécile, Miaz, Leila, Bodet, Damien, Deparis, Marianna, Gaudichon, Jérémie, Dore, Eric, Kanold, Justyna, Briandet, Claire, Desplantes, Claire, Neuman, Florent, Adjaoud, Dalila, Armari-Alla, Corinne, Plantaz, Dominique, Perret, Cécile, Bruno, Bénedicte, Nelken, Brigitte, Piguet, Christophe, Bertrand, Yves, Garnier, Nathalie, Kebaili, Kamila, Ouachee, Marie, Coze, Carole, Curtillet, Catherine, Gentet, Jean-Claude, Michel, Gérard, Galambrun, Claire, Chastagner, Pascal, Boutroux, Hélène, Landman-Parker, Judith, Bodak, Nathalie, Leverger, Guy, Petit, Arnaud, Simonin, Mathieu, Tabone, Marie-Dominique, Bader-Meunier, Brigitte, Blanche, Stéphane, Castelle, Martin, Neven, Bénédicte, Bodemer, Christine, Perrin, Olivia Boccara, Aerts, Isabelle, Orbach, Daniel, Bourdeaut, Franck, Brugieres, Laurence, Dufour, Christelle, Minard, Véronique, Valteau-Couanet, Dominique, Blanc, Laurence, Millot, Frédéric, Guimard, Grégory, Pluchart, Claire, Bonneau, Jacinthe, Chappe, Céline, Taque, Sophie, Pertuisel, Sophie, Gandemer, Virginie, Probert, Jamie, Puiseux, Chloé, Buchbinder, Nimrod, Dumesnil, Cécile, Filhon, Bruno, Marie-Cardine, Aude, Schneider, Pascale, Berger, Claire, Thouvenin-Doulet, Sandrine, Entz-Werle, Natacha, Paillard, Catherine, Spiegel, Alexandra, Plat, Geneviève, Blouin, Pascale, Jourdain, Anne, Yvert-Guillebert, Marion, Jehanne, Mathilde, Benadiba, Joy, Soler, Christine, Poiree, Maryline, Haouy, Stéphanie, Sirvent, Nicolas, Saumet, Laure, Thalhammer, Julian ^{1, 2}, Jeziorski, Eric ³, Marec-Bérard, Perrine ¹, Barkaoui, Mohamed Aziz ⁴, Pagnier, Anne ⁵, Rohrlich, Pierre-Simon ⁶, Chevallier, Aurore ⁴, Carausu, Liana ⁷, Aladjidi, Nathalie ⁸, Rigaud, Charlotte ⁹, Leruste, Amaury ¹⁰, Azarnoush, Saba ¹¹, Lauvray, Thomas ¹², Le Louet, Solenne ⁴, Treguier, Pauline ¹⁴, Mansuy, Ludovic ¹⁵, Pasquet, Marlene ¹⁶, Olivier, Laura ¹⁶, Rome, Angélique ¹⁷, Saultier, Paul ¹⁷, Isfan, Fiorentina ¹⁸, Renard, Cécile ¹, Li Thiao Te, Valerie ¹⁹, Salmon, Alexandra ²⁰, Abou Chahla, Wadih ², Lambilliotte, Anne ², Stephan, Jean-Louis ²², Geissmann, Frederic ²³, Lejeune, Julien ²⁴, Mallebranche, Coralie ²⁵, Reguerre, Yves ²⁶, Grain, Audrey ²⁷, Thomas, Caroline ²⁷, Hélias-Rodzewicz, Zofia ²⁸, Moshous, Despina ²⁹, Fenneteau, Odile ³⁰, Coulomb-L’Hermine, Aurore ³¹, Lapillonne, Hélène ³², de Saint-Basile, Geneviève ³³, Emile, Jean-François ²⁸, Héritier, Sébastien ⁴, Donadieu, Jean ^{4, ∗}

Source: In Blood 6 March 2025 145(10):1061-1073

Bone sarcomas and cancer predisposition syndromes

Alternate Title: Sarcomes osseux et syndromes de prédisposition au cancer (French)

Authors: Tlemsani, Camille ^{1, 2}, Bougeard, Gaëlle ³, Gauthier-Villars, Marion ⁴, Denizeau, Philippe ⁵, Winter, Sarah ⁶, Michot, Caroline ⁷, Baujat, Geneviève ⁷, Bressac, Brigitte ⁸, Adam de Beaumais, Tiphaine ⁹, Rouchaud, Aymeric ¹⁰, Mihoubi-Bouvier, Fadila ¹¹, Bourdeaut, Franck ⁶, Brugières, Laurence ¹², Leblanc, Thierry ¹³, Kasper, Edwige ³, Corradini, Nadège ^{14, *}

Source: In Bulletin du Cancer

Mutational signature, cancer driver genes mutations and transcriptomic subgroups predict hepatoblastoma survival

Authors: Pire, Aurore, Hirsch, Theo Z., Morcrette, Guillaume, Imbeaud, Sandrine, Gupta, Barkha, Pilet, Jill, Cornet, Marianna, Fabre, Monique, Guettier, Catherine, Branchereau, Sophie, Brugières, Laurence, Guerin, Florent, Laithier, Véronique, Coze, Carole, Nagae, Genta, Hiyama, Eiso, Laurent-Puig, Pierre, Rebouissou, Sandra, Sarnacki, Sabine, Chardot, Christophe, Capito, Carmen, Faure-Conter, Cécile, Aerts, Isabelle, Taque, Sophie, Fresneau, Brice, Zucman-Rossi, Jessica

Source: In European Journal of Cancer March 2024 200

Patient‐derived xenograft models of ALK+ ALCL reveal preclinical promise for therapy with brigatinib

Authors: Prokoph, Nina, Matthews, Jamie D., Trigg, Ricky M., Montes‐Mojarro, Ivonne A., Burke, G. A. Amos, Fend, Falko, Merkel, Olaf, Kenner, Lukas, Geoerger, Birgit, Johnston, Robert, Murray, Matthew J., Riguad, Charlotte, Brugières, Laurence, Turner, Suzanne D.

Source: British journal of haematology. 202(5):985-994

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195880894.0x000001&indx=1&recIds=ETOCvdc_100195880894.0x000001

Late toxicity comparison of alkylating‐based maintenance regimen with cyclophosphamide (VAC) vs ifosfamide (VAI) in Ewing sarcoma survivors treated in the randomized clinical trial Euro‐EWING99‐R1 in France

Authors: Corvest, Victoria, Marec‐Bérard, Perrine, Lervat, Cyril, Pacquement, Hélène, Toulmonde, Maud, Gentet, Jean‐Claude, Laurence, Valérie, Cleirec, Morgane, Mansuy, Ludovic, Bompas, Emmanuelle, Castex, Marie‐Pierre, Taque, Sophie, Filhon, Bruno, Tabone, Marie‐Dominique, Verité, Cécile, Entz‐Werle, Natacha, Saumet, Laure, Guimard, Gregory, Pondrom, Morgane, Chevreau, Christine, Flandrin, Jennifer, Duranteau, Lise, Rousset‐Jablonski, Christine, Brugières, Laurence, Jimenez, Marta, Le Deley, Marie‐Cécile, Gaspar, Nathalie, Fresneau, Brice

Source: International journal of cancer. 152(8):1659-1667

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173650083.0x000001&indx=1&recIds=ETOCvdc_100173650083.0x000001

Efficacy and safety of crizotinib in ALK-positive systemic anaplastic large-cell lymphoma in children, adolescents, and adult patients: results of the French AcSé-crizotinib trial

Authors: Brugières, Laurence, Cozic, Nathalie, Houot, Roch, Rigaud, Charlotte, Sibon, David, Arfi-Rouche, Julia, Bories, Pierre, Cottereau, Anne S., Delmer, Alain, Ducassou, Stephane, Garnier, Nathalie, Lamant, Laurence, Leruste, Amaury, Millot, Frederic, Moalla, S., Morschhauser, Franck, Nolla, Marie, Pagnier, Anne, Reguerre, Yves, Renaud, Loic, Schmitt, Anne, Simonin, Mathieu, Verschuur, Arnaud, Hoog Labouret, Nathalie, Mahier Ait Oukhatar, Celine, Vassal, Gilles

Source: In European Journal of Cancer September 2023 191

Pediatric Tumors and Developmental Anomalies: A French Nationwide Cohort Study

Authors: Semeraro, Michaela, Fouquet, Cyrielle, Vial, Yoann, Amiel, Jeanne, Galmiche, Louise, Cretolle, Célia, Blanc, Thomas, Jolaine, Valérie, Garcelon, Nicolas, Entz-Werle, Natacha, Pellier, Isabelle, Vérité, Cécile, Sophie Taque, Coulomb, Aurore, Petit, Arnaud, Corradini, Nadège, Bouazza, Naim, Lacour, Brigitte, Clavel, Jacqueline, Brugières, Laurence, Bourdeaut, Franck, Sarnacki, Sabine

Source: In The Journal of Pediatrics August 2023 259

Constitutional Microsatellite Instability, Genotype, and Phenotype Correlations in Constitutional Mismatch Repair Deficiency

Authors: Gallon, Richard, Phelps, Rachel, Hayes, Christine, Brugieres, Laurence, Guerrini-Rousseau, Léa, Colas, Chrystelle, Muleris, Martine, Ryan, Neil A.J., Evans, D. Gareth, Grice, Hannah, Jessop, Emily, Kunzemann-Martinez, Annabel, Marshall, Lilla, Schamschula, Esther, Oberhuber, Klaus, Azizi, Amedeo A., Baris Feldman, Hagit, Beilken, Andreas, Brauer, Nina, Brozou, Triantafyllia, Dahan, Karin, Demirsoy, Ugur, Florkin, Benoît, Foulkes, William, Januszkiewicz-Lewandowska, Danuta, Jones, Kristi J., Kratz, Christian P., Lobitz, Stephan, Meade, Julia, Nathrath, Michaela, Pander, Hans-Jürgen, Perne, Claudia, Ragab, Iman, Ripperger, Tim, Rosenbaum, Thorsten, Rueda, Daniel, Sarosiek, Tomasz, Sehested, Astrid, Spier, Isabel, Suerink, Manon, Zimmermann, Stefanie-Yvonne, Zschocke, Johannes, Borthwick, Gillian M., Wimmer, Katharina, Burn, John, Jackson, Michael S., Santibanez-Koref, Mauro

Source: In Gastroenterology April 2023 164(4):579-592

Improving outcomes of childhood and young adult non-Hodgkin lymphoma: 25 years of research and collaboration within the framework of the European Intergroup for Childhood Non-Hodgkin Lymphoma

Authors: Beishuizen, Auke ^†, Mellgren, Karin ^†, Andrés, Mara, Auperin, Anne, Bacon, Chris M, Bomken, Simon, Burke, G A Amos, Burkhardt, Birgit, Brugieres, Laurence, Chiang, Alan K S, Damm-Welk, Christine, d'Amore, Emanuele, Horibe, Keizo, Kabickova, Edita, Khanam, Tasneem, Kontny, Udo, Klapper, Wolfram, Lamant, Laurence, Le Deley, Marie-Cecile, Loeffen, Jan, Macintyre, Elizabeth, Mann, Georg, Meyer-Wentrup, Friederike, Michgehl, Ulf, Minard-Colin, Veronique, Mussolin, Lara, Oschlies, Ilske, Patte, Catherine, Pillon, Marta, Reiter, Alfred, Rigaud, Charlotte, Ronceray, Leila, Salaverria, Itziar, Simonitsch-Klupp, Ingrid, Uyttebroeck, Anne, Verdu-Amoros, Jaime, Williams, Denise, Woessmann, Wilhelm, Wotherspoon, Andrew, Wrobel, Grazyna, Zimmermann, Martin, Attarbaschi, Andishe ^†, Turner, Suzanne D ^{†, *}

Source: In The Lancet Haematology March 2023 10(3):e213-e224

Diagnosis and management of ALK-positive anaplastic large cell lymphoma in children and adolescents

Authors: Rigaud, Charlotte, Knörr, Fabian, Brugières, Laurence, Woessmann, Wilhelm

Source: In Best Practice & Research Clinical Haematology March 2023 36(1)

Tyrosine phosphatases regulate resistance to ALK inhibitors in ALK+ anaplastic large cell lymphoma

Authors: Karaca Atabay, Elif, Mecca, Carmen, Wang, Qi, Ambrogio, Chiara, Mota, Ines, Prokoph, Nina, Mura, Giulia, Martinengo, Cinzia, Patrucco, Enrico, Leonardi, Giulia, Hossa, Jessica, Pich, Achille, Mologni, Luca, Gambacorti-Passerini, Carlo, Brugières, Laurence, Geoerger, Birgit, Turner, Suzanne D., Voena, Claudia, Cheong, Taek-Chin, Chiarle, Roberto

Source: Blood. 139(5):717-731

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183249562.0x000001&indx=1&recIds=ETOCvdc_100183249562.0x000001

Association Between Perinatal Factors and Childhood Lymphoma—A Pooled Analysis of the ESCALE and ESTELLE Studies (SFCE).

Authors: Msallem, Elissa, Pacquement, Hélène, Olivier, Laura, Brugières, Laurence, Landman Parker, Judith, Garnier, Nathalie, Lambilliotte, Anne, Faure, Laure, Clavel, Jacqueline, Bonaventure, Audrey

Source: Pediatric Blood & Cancer; Feb2025, Vol. 72 Issue 2, p1-13, 13p

Minimal Residual Disease Monitoring Using a 3′ALK Universal Probe Assay in ALK-Positive Anaplastic Large-Cell Lymphoma

Authors: Quelen, Cathy, Grand, David, Sarot, Emeline, Brugières, Laurence, Sibon, David, Pradines, Anne, Laurent, Camille, Brousset, Pierre, Lamant, Laurence

Source: Journal of molecular diagnostics. 23(2):131-139

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100134777282.0x000001&indx=1&recIds=ETOCvdc_100134777282.0x000001

Neuro‐meningeal relapse in anaplastic large‐cell lymphoma: incidence, risk factors and prognosis – a report from the European intergroup for childhood non‐Hodgkin lymphoma

Authors: Del Baldo, Giada, Abbas, Rachid, Woessmann, Wilhelm, Horibe, Keizo, Pillon, Marta, Burke, Amos, Beishuizen, Auke, Rigaud, Charlotte, Le Deley, Marie‐Cécile, Lamant, Laurence, Brugières, Laurence

Source: British journal of haematology. 192(6):1039-1048

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100119156696.0x000001&indx=1&recIds=ETOCvdc_100119156696.0x000001

Report of the sixth meeting of the European Consortium 'Care for CMMRD' (C4CMMRD), Paris, France, November 16th 2022.

Authors: Guerrini-Rousseau, Léa, Gallon, Richard, Pineda, Marta, Brugières, Laurence, Baert-Desurmont, Stéphanie, Corsini, Carole, Dangouloff-Ros, Volodia, Gorris, Mark A. J., Haberler, Christine, Hoarau, Pauline, Jongmans, Marjolijn C., Kloor, Matthias, Loeffen, Jan, Rigaud, Charlotte, Robbe, Julie, Vibert, Roseline, Weijers, Dilys, Wimmer, Katharina, Colas, Chrystelle

Source: Familial Cancer; Nov2024, Vol. 23 Issue 4, p447-457, 11p

Subject Terms: COVID-19 pandemic, CONSORTIA, GERM cells

IL10RA modulates crizotinib sensitivity in NPM1-ALK+ anaplastic large cell lymphoma

Authors: Prokoph, Nina ¹, Probst, Nicola A. ¹, Lee, Liam C. ¹, Monahan, Jack M. ², Matthews, Jamie D. ¹, Liang, Huan-Chang ³, Bahnsen, Klaas ¹, Montes-Mojarro, Ivonne A. ⁴, Karaca-Atabay, Elif ^{5, 6}, Sharma, Geeta G. ⁷, Malik, Vikas ⁸, Larose, Hugo ¹, Forde, Sorcha D. ¹, Ducray, Stephen P. ¹, Lobello, Cosimo ⁹, Wang, Qi ⁵, Luan, Shi-Lu ¹, Pospíšilová, Šárka ^{9, 10}, Gambacorti-Passerini, Carlo ⁷, Burke, G. A. Amos ¹¹, Pervez, Shahid ¹², Attarbaschi, Andishe ^{13, 14}, Janíková, Andrea ¹⁰, Pacquement, Hélène ¹⁵, Landman-Parker, Judith ¹⁶, Lambilliotte, Anne ¹⁷, Schleiermacher, Gudrun ^{18, 19, 20}, Klapper, Wolfram ²¹, Jauch, Ralf ²², Woessmann, Wilhelm ²³, Vassal, Gilles ²⁴, Kenner, Lukas ^{25, 26, 27, 28}, Merkel, Olaf ³, Mologni, Luca ⁷, Chiarle, Roberto ^{5, 6}, Brugières, Laurence ²⁹, Geoerger, Birgit ^{29, 30}, Barbieri, Isaia ¹, Turner, Suzanne D. ^{1, 1, 9}

Source: In Blood 1 October 2020 136(14):1657-1669

A multicentric randomized phase II clinical trial evaluating high-dose thiotepa as adjuvant treatment to standard chemotherapy in patients with resectable relapsed osteosarcoma

Authors: Marec-Berard, Perrine, Dalban, Cécile, Gaspar, Nathalie, Brugieres, Laurence, Gentet, Jean-Claude, Lervat, Cyril, Corradini, Nadège, Castex, Marie-Pierre, Schmitt, Claudine, Pacquement, Hélène, Tabone, Marie-Dominique, Brahmi, Mehdi, Metzger, Séverine, Blay, Jean-Yves, Pérol, David

Source: In European Journal of Cancer January 2020 125:58-68

An alternative approach to establishing unbiased colorectal cancer risk estimation in Lynch syndrome

Authors: Suerink, Manon, Rodríguez-Girondo, Mar, van der Klift, Heleen M., Colas, Chrystelle, Brugieres, Laurence, Lavoine, Noémie, Jongmans, Marjolijn, Munar, Gabriel Capellá, Evans, D. Gareth, Farrell, Michael P., Genuardi, Maurizio, Goldberg, Yael, Gomez-Garcia, Encarna, Heinimann, Karl, Hoell, Jessica I., Aretz, Stefan, Jasperson, Kory W., Kedar, Inbal, Modi, Mitul B., Nikolaev, Sergey, van Os, Theo A.M., Ripperger, Tim, Rueda, Daniel, Senter, Leigha, Sjursen, Wenche, Sunde, Lone, Therkildsen, Christina, Tibiletti, Maria G., Trainer, Alison H., Vos, Yvonne J., Wagner, Anja, Winship, Ingrid, Wimmer, Katharina, Zimmermann, Stefanie Y., Vasen, Hans F., van Asperen, Christi J., Houwing-Duistermaat, Jeanine J., ten Broeke, Sanne W., Nielsen, Maartje

Source: In Genetics in Medicine December 2019 21(12):2706-2712

Denosumab for treating aneurysmal bone cysts in children

Authors: Raux, Sébastien, Bouhamama, Amine, Gaspar, Nathalie, Brugières, Laurence, Entz-Werlé, Natacha, Mallet, Cindy, Dijoud, Frédérique, Gouin, François, Marec-Bérard, Perrine

Source: In Orthopaedics & Traumatology: Surgery & Research October 2019 105(6):1181-1185

Intérêt du denosumab dans le traitement des kystes osseux anévrysmatiques de l’enfant

Alternate Title: Denosumab for treating aneurysmal bone cysts in children (English)

Authors: Raux, Sébastien, Bouhamama, Amine, Gaspar, Nathalie, Brugières, Laurence, Entz-werlé, Natacha, Mallet, Cindy, Dijoud, Frédérique, Gouin, François, Marec-Bérard, Perrine

Source: In Revue de Chirurgie Orthopedique et Traumatologique October 2019 105(6):769-773