Vaccine-associated enhanced respiratory pathology in COVID-19 hamsters after TH2-biased immunization

Authors: Ebenig, Aileen, Muraleedharan, Samada, Kazmierski, Julia, Todt, Daniel, Auste, Arne, Anzaghe, Martina, Gömer, André, Postmus, Dylan, Gogesch, Patricia, Niles, Marc, Plesker, Roland, Miskey, Csaba, Gellhorn Serra, Michelle, Breithaupt, Angele, Hörner, Cindy, Kruip, Carina, Ehmann, Rosina, Ivics, Zoltan, Waibler, Zoe, Pfaender, Stephanie, Wyler, Emanuel, Landthaler, Markus, Kupke, Alexandra, Nouailles, Geraldine, Goffinet, Christine, Brown, Richard J.P., Mühlebach, Michael D.

Source: In Cell Reports 16 August 2022 40(7)

Generation of hiPSC-derived low threshold mechanoreceptors containing axonal termini resembling bulbous sensory nerve endings and expressing Piezo1 and Piezo2

Authors: Zhu, Shuyong, Stanslowsky, Nancy, Fernández-Trillo, Jorge, Mamo, Tamrat M., Yu, Pengfei, Kalmbach, Norman, Ritter, Birgit, Eggenschwiler, Reto, Ouwendijk, Werner J.D., Mzinza, David, Tan, Likai, Leffler, Andreas, Spohn, Michael, Brown, Richard J.P., Kropp, Kai A., Kaever, Volkhard, Ha, Teng-Cheong, Narayanan, Pratibha, Grundhoff, Adam, Förster, Reinhold, Schambach, Axel, Verjans, Georges M.G.M., Schmidt, Manuela, Kispert, Andreas, Cantz, Tobias, Gomis, Ana, Wegner, Florian, Viejo-Borbolla, Abel

Source: In Stem Cell Research October 2021 56

C19orf66 is an interferon-induced inhibitor of HCV replication that restricts formation of the viral replication organelle

Authors: Kinast, Volker, Plociennikowska, Agnieszka, Anggakusuma, Bracht, Thilo, Todt, Daniel, Brown, Richard J.P., Boldanova, Tujana, Zhang, Yudi, Brüggemann, Yannick, Friesland, Martina, Engelmann, Michael, Vieyres, Gabrielle, Broering, Ruth, Vondran, Florian W.R., Heim, Markus H., Sitek, Barbara, Bartenschlager, Ralf, Pietschmann, Thomas, Steinmann, Eike

Source: In Journal of Hepatology September 2020 73(3):549-558

A central hydrophobic E1 region controls the pH range of hepatitis C virus membrane fusion and susceptibility to fusion inhibitors

Authors: Banda, Dominic H. ¹, Perin, Paula M. ¹, Brown, Richard J.P. ¹, Todt, Daniel ^{1, 2}, Solodenko, Wladimir ³, Hoffmeyer, Patrick ³, Kumar Sahu, Kamlesh ⁴, Houghton, Michael ⁴, Meuleman, Philip ⁵, Müller, Rolf ⁶, Kirschning, Andreas ³, Pietschmann, Thomas ^{1, 7, ⁎}

Source: In Journal of Hepatology June 2019 70(6):1082-1092

Functional and immunogenic characterization of diverse HCV glycoprotein E2 variants

Authors: Khera, Tanvi, Behrendt, Patrick, Bankwitz, Dorothea, Brown, Richard J.P., Todt, Daniel, Doepke, Mandy, Khan, Abdul Ghafoor, Schulze, Kai, Law, John, Logan, Michael, Hockman, Darren, Wong, Jason Alexander Ji-Xhin, Dold, Leona, Gonzalez-Motos, Victor, Spengler, Ulrich, Viejo-Borbolla, Abel, Ströh, Luisa J, Krey, Thomas, Tarr, Alexander W., Steinmann, Eike, Manns, Michael P., Klein, Florian, Guzman, Carlos A., Marcotrigiano, Joseph, Houghton, Michael, Pietschmann, Thomas

Source: In Journal of Hepatology April 2019 70(4):593-602

Immunization with a synthetic consensus hepatitis C virus E2 glycoprotein ectodomain elicits virus-neutralizing antibodies

Authors: Tarr, Alexander W., Backx, Matthijs, Hamed, Mohamed R., Urbanowicz, Richard A., McClure, C. Patrick, Brown, Richard J.P., Ball, Jonathan K.

Source: In Antiviral Research December 2018 160:25-37

Tracking HCV protease population diversity during transmission and susceptibility of founder populations to antiviral therapy

Authors: Khera, Tanvi, Todt, Daniel, Vercauteren, Koen, McClure, C. Patrick, Verhoye, Lieven, Farhoudi, Ali, Bhuju, Sabin, Geffers, Robert, Baumert, Thomas F., Steinmann, Eike, Meuleman, Philip, Pietschmann, Thomas, Brown, Richard J.P.

Source: In Antiviral Research March 2017 139:129-137

Exacerbation d’infection par le virus de l’hépatite E au cours d’un traitement par anti-TNFα

Authors: Behrendt, Patrick, Lüth, Stefan, Dammermann, Werner, Drave, Svenja, Brown, Richard J.P., Todt, Daniel, Schnoor, Ulrike, Steinmann, Eike, Wedemeyer, Heiner, Pischke, Sven, Iking-Konert, Christof

Source: Revue du rhumatisme. 84(3):244-247

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100043706022.0x000001&indx=1&recIds=ETOCvdc_100043706022.0x000001

Development of a high-throughput pyrosequencing assay for monitoring temporal evolution and resistance associated variant emergence in the Hepatitis C virus protease coding-region

Authors: Irving, William L., Rupp, Daniel, McClure, C. Patrick, Than, Lwin Mar, Titman, Andrew, Ball, Jonathan K., Steinmann, Eike, Bartenschlager, Ralf, Pietschmann, Thomas, Brown, Richard J.P.

Source: In Antiviral Research October 2014 110:52-59

Hepatitis C Virus

Authors: Pietschmann, Thomas, Brown, Richard J.P.

Source: In Trends in Microbiology April 2019 27(4):379-380

Exacerbation of hepatitis E virus infection during anti-TNFα treatment

Authors: Behrendt, Patrick, Lüth, Stefan, Dammermann, Werner, Drave, Svenja, Brown, Richard J.P., Todt, Daniel, Schnoor, Ulrike, Steinmann, Eike, Wedemeyer, Heiner, Pischke, Sven, Iking-Konert, Christof

Source: Joint bone spine. 84(2):217-219

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100042593329.0x000001&indx=1&recIds=ETOCvdc_100042593329.0x000001

Recombinant Human L-Ficolin Directly Neutralizes Hepatitis C Virus Entry.

Authors: Hamed, Mohamed R.¹, Brown, Richard J.P.¹, Zothner, Carsten¹, Urbanowicz, Richard a.¹, Mason, Christopher P.¹, Krarup, anders¹, McClure, C. Patrick¹, Irving, William L.¹, Ball, Jonathan K.¹, Harris, Mark¹, Hickling, Timothy P.¹, Tarr, alexander W.¹ alex.tarr@nottingham.ac.uk

Source: Journal of Innate Immunity. Aug2014, Vol. 6 Issue 5, p676-684. 9p.

Flunarizine prevents hepatitis C virus membrane fusion in a genotype-dependent manner by targeting the potential fusion peptide within E1.

Authors: Perin, Paula M., Haid, Sibylle, Brown, Richard J.P., Doerrbecker, Juliane, Schulze, Kai, Zeilinger, Carsten, von Schaewen, Markus, Heller, Brigitte, Vercauteren, Koen, Luxenburger, Eva, Baktash, Yasmine M., Vondran, Florian W.R., Speerstra, Sietkse, Awadh, Abdullah, Mukhtarov, Furkat, Schang, Luis M., Kirschning, Andreas, Müller, Rolf, Guzman, Carlos A., Kaderali, Lars

Source: Hepatology (02709139); Jan2016, Vol. 63 Issue 1, p49-62, 14p

Clinical course of infection and viral tissue tropism of hepatitis C virus-like nonprimate hepaciviruses in horses.

Authors: Pfaender, Stephanie, Cavalleri, Jessika M.V., Walter, Stephanie, Doerrbecker, Juliane, Campana, Benedetta, Brown, Richard J.P., Burbelo, Peter D., Postel, Alexander, Hahn, Kerstin, Anggakusuma, Riebesehl, Nina, Baumgärtner, Wolfgang, Becher, Paul, Heim, Markus H., Pietschmann, Thomas, Feige, Karsten, Steinmann, Eike

Source: Hepatology (02709139); Feb2015, Vol. 61 Issue 2, p448-459, 12p

Incorporation of primary patient-derived glycoproteins into authentic infectious hepatitis C virus particles.

Authors: Doerrbecker, Juliane, Friesland, Martina, Riebesehl, Nina, Ginkel, Corinne, Behrendt, Patrick, Brown, Richard J.P., Ciesek, Sandra, Wedemeyer, Heiner, Sarrazin, Christoph, Kaderali, Lars, Pietschmann, Thomas, Steinmann, Eike

Source: Hepatology (02709139); Aug2014, Vol. 60 Issue 2, p508-520, 13p

Cell entry, efficient RNA replication, and production of infectious hepatitis C virus progeny in mouse liver-derived cells.

Authors: Frentzen, Anne, Anggakusuma, Gürlevik, Engin, Hueging, Kathrin, Knocke, Sarah, Ginkel, Corinne, Brown, Richard J.P., Heim, Markus, Dill, Michael T., Kröger, Andrea, Kalinke, Ulrich, Kaderali, Lars, Kuehnel, Florian, Pietschmann, Thomas

Source: Hepatology (02709139); Jan2014, Vol. 59 Issue 1, p78-88, 11p

Yellow Fever: Integrating Current Knowledge with Technological Innovations to Identify Strategies for Controlling a Re-Emerging Virus.

Authors: Kleinert, Robin D.V., Montoya-Diaz, Eduardo, Khera, Tanvi, Welsch, Kathrin, Tegtmeyer, Birthe, Hoehl, Sebastian, Ciesek, Sandra, Brown, Richard J.P.

Source: Viruses (1999-4915); Oct2019, Vol. 11 Issue 10, p960-960, 1p

Subject Terms: YELLOW fever, TECHNOLOGICAL innovations, HEMORRHAGIC fever, MOSQUITO vectors, PHYTOPLASMAS, SHORTWAVE radio, VIRUSES, TECHNOLOGICAL obsolescence