Binding of two zinc ions promotes liquid-liquid phase separation of Tau

Authors: Yatoui, Dahbia, Tsvetkov, Philipp O., La Rocca, Romain, Baksheeva, Viktoriia E., Allegro, Diane, Breuzard, Gilles, Ferracci, Géraldine, Byrne, Deborah, Devred, François

Source: In International Journal of Biological Macromolecules 31 December 2022 223 Part A:1223-1229

Therapeutic Contribution of Tau-Binding Thiazoloflavonoid Hybrid Derivatives Against Glioblastoma Using Pharmacological Approach in 3D Spheroids.

Authors: Relave, Emmanuelle T., Hedna, Rayane, Di Maio, Attilio, Devred, François, Kovacic, Hervé, Robin, Maxime, Breuzard, Gilles

Source: International Journal of Molecular Sciences; Nov2024, Vol. 25 Issue 21, p11785, 14p

Subject Terms: BRAIN tumors, MICROTUBULE-associated proteins, TAU proteins, GLIOBLASTOMA multiforme

Synthesis and biological evaluation of 4 arylcoumarin analogues as tubulin-targeting antitumor agents

Authors: Mutai, Peggoty, Breuzard, Gilles, Pagano, Alessandra, Allegro, Diane, Peyrot, Vincent, Chibale, Kelly

Source: In Bioorganic & Medicinal Chemistry 1 March 2017 25(5):1652-1665

Interactions of long-chain homologues of colchicine with tubulin

Authors: Marzo-Mas, Ana, Barbier, Pascale, Breuzard, Gilles, Allegro, Diane, Falomir, Eva, Murga, Juan, Carda, Miguel, Peyrot, Vincent, Marco, J. Alberto

Source: In European Journal of Medicinal Chemistry 27 January 2017 126:526-535

Saccharomyces boulardii CNCM I-745 Restores intestinal Barrier Integrity by Regulation of E-cadherin Recycling

Authors: Terciolo, Chloé, Dobric, Aurélie, Ouaissi, Mehdi, Siret, Carole, Breuzard, Gilles, Silvy, Françoise, Marchiori, Bastien, Germain, Sébastien, Bonier, Renaté, Hama, Adel

Source: Journal of Crohn's and colitis. 11(8):999-1010

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN620511648&indx=1&recIds=ETOCRN620511648

Tau Interaction with Tubulin and Microtubules: From Purified Proteins to Cells

Authors: De Bessa, Tiphany, Breuzard, Gilles, Allegro, Diane, Devred, François, Peyrot, Vincent, Barbier, Pascale

Source: Methods in molecular biology. 1523:61-88

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN609747120&indx=1&recIds=ETOCRN609747120

2-Aminothiazole-Flavonoid Hybrid Derivatives Binding to Tau Protein and Responsible for Antitumor Activity in Glioblastoma.

Authors: Hedna, Rayane, DiMaio, Attilio, Robin, Maxime, Allegro, Diane, Tatoni, Mario, Peyrot, Vincent, Barbier, Pascale, Kovacic, Hervé, Breuzard, Gilles

Source: International Journal of Molecular Sciences; Oct2023, Vol. 24 Issue 20, p15050, 27p

Subject Terms: TAU proteins, CARRIER proteins, PROTEIN binding, ANTINEOPLASTIC agents, GLIOBLASTOMA multiforme

Myotoxin-3 from the Pacific Rattlesnake Crotalus oreganus oreganus Venom Is a New Microtubule-Targeting Agent.

Authors: González García, María Cecilia, Radix, Caroline, Villard, Claude, Breuzard, Gilles, Mansuelle, Pascal, Barbier, Pascale, Tsvetkov, Philipp O., De Pomyers, Harold, Gigmes, Didier, Devred, François, Kovacic, Hervé, Mabrouk, Kamel, Luis, José

Source: Molecules; Dec2022, Vol. 27 Issue 23, p8241, 19p

Subject Terms: VENOM, CROTALUS, RATTLESNAKES, TUBULINS, PEPTIDES, MICROTUBULES, HETERODIMERS

Tau Protein as Therapeutic Target for Cancer? Focus on Glioblastoma.

Authors: Hedna, Rayane, Kovacic, Hervé, Pagano, Alessandra, Peyrot, Vincent, Robin, Maxime, Devred, François, Breuzard, Gilles

Source: Cancers; Nov2022, Vol. 14 Issue 21, p5386, 33p

Subject Terms: TAU proteins, CARCINOGENESIS, GLIOMAS, CELLULAR signal transduction, CELL motility, PHOSPHORYLATION

Energy transfer to analyse membrane-integrated mitoxantrone in BCRP-overexpressed cells

Authors: Breuzard, Gilles, El-Khoury, Victoria, Millot, Christine, Manfait, Michel, Millot, Jean-Marc

Source: In Journal of Photochemistry & Photobiology, B: Biology 2007 87(2):113-123

Selective Interactions of Ethidiums with G-Quadruplex DNA Revealed by Surface-Enhanced Raman Scattering.

Authors: Breuzard, Gilles, Millot, Jean-Marc, Riou, Jean-François

Source: Analytical Chemistry; August 15 2003, Vol. 75 Issue 16, p4305-4311, 7p

Tau Regulates Glioblastoma Progression, 3D Cell Organization, Growth and Migration via the PI3K-AKT Axis.

Authors: Pagano, Alessandra¹ (AUTHOR) alessandra.pagano@univ-amu.fr, Breuzard, Gilles¹ (AUTHOR) fabrice.parat@univ-amu.fr, Parat, Fabrice¹ (AUTHOR) garroustefrancoise@gmail.com, Tchoghandjian, Aurélie² (AUTHOR) aurelie.tchoghandjian@univ-amu.fr, Figarella-Branger, Dominique^2,3 (AUTHOR) dominique.figarella-branger@univ-amu.fr, De Bessa, Tiphany Coralie⁴ (AUTHOR) debessa@hotmail.fr, Garrouste, Françoise¹ (AUTHOR) alexisdouence@gmail.com, Douence, Alexis¹ (AUTHOR) pascale.barbier@univ-amu.fr, Barbier, Pascale¹ (AUTHOR) herve.kovacic@univ-amu.fr, Kovacic, Hervé¹ (AUTHOR)

Source: Cancers. Nov2021, Vol. 13 Issue 22, p5818. 1p.

Subject Terms: *SERINE metabolism, *CELL migration, *TAU proteins, *ANIMAL experimentation, *MICROBIOLOGICAL assay, *GLIOMAS, *CELL physiology, *RNA, *CELL communication, *GENE expression, *CELLULAR signal transduction, *RESEARCH funding, *PHOSPHORYLATION, *ANIMALS, *MICE

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