Efficient synthesis for each of the eight stereoisomers of the iminosugars lentiginosine and 1,4-dideoxy-1,4-imino-D-arabinitol (DAB)

Authors: Liotta, Louis J., Antoine, Jessica, Brammer Basta, Leighanne A., Campbell, Andrew S., Cole, Gabrielle Y., Demick Brazile, Kristen A., Dogal Gardner, Natalie M., Fitzgerald, Megan E., Francois, Jean E.K., French, Brian M., Garafola, Sara L., Giannetti, Catherine A., Granatosky, Eve A., Harney, Alycen M., Hummel, James T., Joyce, Andrew P., Keylor, Mitchell H., Khubchandani, Jasmine A., Korzeniecki, Claudia, Lieberman, Diana C., Litterio, Joshua M., Maiorano, Madison O., Marshall, Jessica F., McCarthy, Kelly A., Mendes Vieira, Andreia, Miller, Ruby M., Morrison, Emily R., Moura, Steven P., Neumann, Dillon F., Oliveira, Aliza F., Pace, Nicholas J., Plouffe, Jodie X., Pomfret, Meredith N., Reardon, Katelyn N., Sheller-Miller, Samantha M., Smith, Michael J., Sullivan, Jessica L., Sweeney, Samantha W., Tougas, Kerstin L.

Source: In Carbohydrate Research November 2024 545

Manipulating the 3D organization of the largest synthetic yeast chromosome

Authors: Accardo, Ryan, Brammer Basta, Leighanne A., Bello, Nicholas R., Cai, Lousanna, Cerritos, Stephanie, Cornwell, MacIntosh, D’Amato, Anthony, Hacker, Maria, Hersey, Kenneth, Kennedy, Emma, Kianercy, Ardeshir, Kim, Dohee, McCutcheon, Griffin, McGirr, Kimiko, Meaney, Nora, Nimer, Maisa, Sabbatini, Carla, Scheifele, Lisa Z., Shores, Lucas S., Silvestrone, Cassandra, Snee, Arden, Spina, Antonio, Staiti, Anthony, Stuver, Matt, Tian, Elli, Whearty, Danielle, Zhao, Calvin, Zeller, Karen, Zhang, Weimin, Lazar-Stefanita, Luciana, Yamashita, Hitoyoshi, Shen, Michael J., Mitchell, Leslie A., Kurasawa, Hikaru, Lobzaev, Evgenii, Fanfani, Viola, Haase, Max A.B., Sun, Xiaoji, Jiang, Qingwen, Goldberg, Gregory W., Ichikawa, David M., Lauer, Stephanie L., McCulloch, Laura H., Easo, Nicole, Lin, S. Jiaming, Camellato, Brendan R., Zhu, Yinan, Cai, Jitong, Xu, Zhuwei, Zhao, Yu, Sacasa, Maya, Noyes, Marcus B., Bader, Joel S., Deutsch, Samuel, Stracquadanio, Giovanni, Aizawa, Yasunori, Dai, Junbiao, Boeke, Jef D.

Source: In Molecular Cell 7 December 2023 83(23):4424-4437

Loss of a Functionally and Structurally Distinct ld-Transpeptidase, LdtMt5, Compromises Cell Wall Integrity in Mycobacterium tuberculosis

Authors: Brammer Basta, Leighanne A., Ghosh, Anita, Pan, Ying, Jakoncic, Jean, Lloyd, Evan P. ^**, Townsend, Craig A. ^**, Lamichhane, Gyanu, Bianchet, Mario A.

Source: In Journal of Biological Chemistry 16 October 2015 290(42):25670-25685

Defining critical residues for substrate binding to 1-deoxy- d-xylulose 5-phosphate synthase - active site substitutions stabilize the predecarboxylation intermediate C2α-lactylthiamin diphosphate.

Authors: Brammer Basta, Leighanne A.¹, Patel, Hetalben², Kakalis, Lazaros², Jordan, Frank², Freel Meyers, Caren L.¹

Source: FEBS Journal. Jun2014, Vol. 281 Issue 12, p2820-2837. 18p.

Subject Terms: *PROTEIN binding, *DECARBOXYLATION, *PYROPHOSPHATES, *ENZYMOLOGY, *FLUORESCENT proteins, *PYRUVATES, *SUBSTITUTION reactions, *BINDING sites, *SYNTHASES

Phylogenetic and biochemical analyses of mycobacterial L,D-transpeptidases reveal a distinct enzyme class that is preferentially acylated by meropenem.

Authors: Zandi, Trevor A.¹, Marshburn, Robert L.², Stateler, Paige K.², Brammer Basta, Leighanne A.² basta@usna.edu

Source: ACS Infectious Diseases. 12/13/2019, Vol. 5 Issue 12, p2047-2054. 8p.