In vitro studies of human erythropoiesis using a 3D silk-based bone marrow model that generates erythroblastic islands

Authors: Di Buduo, Christian A. ¹, Careddu, Francesca ¹, Metti, Samuele ², Lunghi, Marco ¹, Diprima, Santo ³, Camilotto, Virginia ^{1, 4}, Bruni, Giovanna ⁵, Gianelli, Umberto ⁶, Tosi, Delfina ⁶, Perotti, Cesare ⁷, Del Fante, Claudia ⁷, Cazzola, Mario ^{1, 4}, Braghetta, Paola ², Kaplan, David L. ⁸, Minetti, Giampaolo ⁹, Malcovati, Luca ^{1, 4}, Balduini, Alessandra ^{1, 8, ∗}

Source: In Blood Advances January 2025

Collagen VI promotes recovery from colitis by inducing lymphangiogenesis and drainage of inflammatory cells

Authors: Molon, Sibilla, Brun, Paola, Scarpa, Melania, Bizzotto, Dario, Zuccolotto, Gaia, Scarpa, Marco, Fassan, Matteo, Angriman, Imerio, Rosato, Antonio, Braghetta, Paola, Castagliuolo, Ignazio, Bonaldo, Paolo

Source: Journal of pathology. 260(4):417-430

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100187530403.0x000001&indx=1&recIds=ETOCvdc_100187530403.0x000001

Lack of COL6/collagen VI causes megakaryocyte dysfunction by impairing autophagy and inducing apoptosis

Authors: Abbonante, Vittorio, Malara, Alessandro, Chrisam, Martina, Metti, Samuele, Soprano, Paolo, Semplicini, Claudio, Bello, Luca, Bozzi, Valeria, Battiston, Monica, Pecci, Alessandro, Pegoraro, Elena, De Marco, Luigi, Braghetta, Paola, Bonaldo, Paolo, Balduini, Alessandra

Source: Autophagy. 19(3):984-999

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100176252591.0x000001&indx=1&recIds=ETOCvdc_100176252591.0x000001

EMILIN1 deficiency causes arterial tortuosity with osteopenia and connects impaired elastogenesis with defective collagen fibrillogenesis

Authors: Adamo, Christin S., Beyens, Aude, Schiavinato, Alvise, Keene, Douglas R., Tufa, Sara F., Mörgelin, Matthias, Brinckmann, Jürgen, Sasaki, Takako, Niehoff, Anja, Dreiner, Maren, Pottie, Lore, Muiño-Mosquera, Laura, Gulec, Elif Yilmaz, Gezdirici, Alper, Braghetta, Paola, Bonaldo, Paolo, Wagener, Raimund, Paulsson, Mats, Bornaun, Helen, De Rycke, Riet, De Bruyne, Michiel, Baeke, Femke, Devine, Walter P., Gangaram, Balram, Tam, Allison, Balasubramanian, Meena, Ellard, Sian, Moore, Sandra, Symoens, Sofie, Shen, Joseph, Cole, Stacey, Schwarze, Ulrike, Holmes, Kathryn W., Hayflick, Susan J., Wiszniewski, Wojciech, Nampoothiri, Sheela, Davis, Elaine C., Sakai, Lynn Y., Sengle, Gerhard, Callewaert, Bert

Source: In The American Journal of Human Genetics 1 December 2022 109(12):2230-2252

Ambra1 deficiency impairs mitophagy in skeletal muscle

Authors: Gambarotto, Lisa, Metti, Samuele, Chrisam, Martina, Cerqua, Cristina, Sabatelli, Patrizia, Armani, Andrea, Zanon, Carlo, Spizzotin, Marianna, Castagnaro, Silvia, Strappazzon, Flavie, Grumati, Paolo, Cescon, Matilde, Braghetta, Paola, Trevisson, Eva, Cecconi, Francesco, Bonaldo, Paolo

Source: Journal of cachexia, sarcopenia and muscle. 13(4):2211-2224

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100158663419.0x000001&indx=1&recIds=ETOCvdc_100158663419.0x000001

Schwann Cell‐Specific Ablation of Beclin 1 Impairs Myelination and Leads to Motor and Sensory Neuropathy in Mice.

Authors: Gambarotto, Lisa^1,2, Russo, Loris¹, Bresolin, Silvia^3,4, Persano, Luca^3,4, D'Amore, Rachele¹, Ronchi, Giulia⁵, Zen, Federica⁵, Muratori, Luisa⁵, Cani, Alice³, Negro, Samuele⁶, Megighian, Aram^7,8, Calabrò, Sonia^1,2, Braghetta, Paola¹, Bizzotto, Dario¹, Cescon, Matilde¹, matilde.cescon@unipd.it

Source: Advanced Science; 2/3/2025, Vol. 12 Issue 5, p1-20, 20p

Ablation of collagen VI leads to the release of platelets with altered function

Authors: Abbonante, Vittorio, Gruppi, Cristian, Battiston, Monica ^*, Zulian, Alessandra ^*, Di Buduo, Christian Andrea ^*, Chrisam, Martina, Sereni, Lucia, Laurent, Pierre-Alexandre, Semplicini, Claudio, Lombardi, Elisabetta, Mazzucato, Mario, Moccia, Francesco, Petronilli, Valeria, Villa, Anna, Bello, Luca, Pegoraro, Elena, Bernardi, Paolo, Braghetta, Paola, De Marco, Luigi, Bonaldo, Paolo, Balduini, Alessandra ^*

Source: In Blood Advances 14 December 2021 5(23):5150-5163

Multimerin-2 maintains vascular stability and permeability

Authors: Pellicani, Rosanna, Poletto, Evelina, Andreuzzi, Eva, Paulitti, Alice, Doliana, Roberto, Bizzotto, Dario, Braghetta, Paola, Colladel, Roberta, Tarticchio, Giulia, Sabatelli, Patrizia, Bucciotti, Francesco, Bressan, Giorgio, Iozzo, Renato V., Colombatti, Alfonso, Bonaldo, Paolo, Mongiat, Maurizio

Source: In Matrix Biology May 2020 87:11-25

Pathogenic Potential of Hic1-Expressing Cardiac Stromal Progenitors

Authors: Soliman, Hesham, Paylor, Ben, Scott, R. Wilder, Lemos, Dario R., Chang, ChihKai, Arostegui, Martin, Low, Marcela, Lee, Christina, Fiore, Daniela, Braghetta, Paola, Pospichalova, Vendula, Barkauskas, Christina E., Korinek, Vladimir, Rampazzo, Alessandra, MacLeod, Kathleen, Underhill, T. Michael, Rossi, Fabio M.V.

Source: In Cell Stem Cell 6 February 2020 26(2):205-220

F-actin dynamics regulates mammalian organ growth and cell fate maintenance

Authors: Pocaterra, Arianna, Santinon, Giulia, Romani, Patrizia, Brian, Irene, Dimitracopoulos, Andrea, Ghisleni, Andrea, Carnicer-Lombarte, Alejandro, Forcato, Mattia, Braghetta, Paola, Montagner, Marco, Galuppini, Francesca, Aragona, Mariaceleste, Pennelli, Gianmaria, Bicciato, Silvio, Gauthier, Nils, Franze, Kristian, Dupont, Sirio

Source: In Journal of Hepatology July 2019 71(1):130-142

Salbutamol repurposing ameliorates neuromuscular junction defects and muscle atrophy in Col6a1^−/− mouse model of collagen VI‐related myopathies.

Authors: Calabrò, Sonia, Nogara, Leonardo, Jian, Yongzhi, Valentin, Manuel, Bizzotto, Dario, Braghetta, Paola, Russo, Loris, Gambarotto, Lisa, Blaauw, Bert, Hashemolhosseini, Said, Bonaldo, Paolo, Cescon, Matilde

Source: Clinical & Translational Medicine; Jul2024, Vol. 14 Issue 7, p1-9, 9p

Subject Terms: CONGENITAL myasthenic syndromes, SPINAL muscular atrophy, BECKER muscular dystrophy, MULTIPLE comparisons (Statistics), RESPIRATORY muscles, FACIOSCAPULOHUMERAL muscular dystrophy

AMBRA1 Controls Regulatory T-Cell Differentiation and Homeostasis Upstream of the FOXO3-FOXP3 Axis

Authors: Becher, Juliane, Simula, Luca, Volpe, Elisabetta, Procaccini, Claudio, La Rocca, Claudia, D’Acunzo, Pasquale, Cianfanelli, Valentina, Strappazzon, Flavie, Caruana, Ignazio, Nazio, Francesca, Weber, Gerrit, Gigantino, Vincenzo, Botti, Gerardo, Ciccosanti, Fabiola, Borsellino, Giovanna, Campello, Silvia, Mandolesi, Georgia, De Bardi, Marco, Fimia, Gian Maria, D’Amelio, Marcello, Ruffini, Francesca, Furlan, Roberto, Centonze, Diego, Martino, Gianvito, Braghetta, Paola, Chrisam, Martina, Bonaldo, Paolo, Matarese, Giuseppe, Locatelli, Franco, Battistini, Luca, Cecconi, Francesco

Source: In Developmental Cell 3 December 2018 47(5):592-607

Role of adiponectin in the metabolism of skeletal muscles in collagen VI–related myopathies

Authors: Gamberi, Tania, Magherini, Francesca, Mannelli, Michele, Chrisam, Martina, Cescon, Matilde, Castagnaro, Silvia, Modesti, Alessandra, Braghetta, Paola, Fiaschi, Tania

Source: Journal of molecular medicine. 97(6):793-801

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100118089469.0x000001&indx=1&recIds=ETOCvdc_100118089469.0x000001

Loss of mitochondrial calcium uniporter rewires skeletal muscle metabolism and substrate preference

Authors: Gherardi, Gaia, Nogara, Leonardo, Ciciliot, Stefano, Fadini, Gian, Blaauw, Bert, Braghetta, Paola, Bonaldo, Paolo, De Stefani, Diego, Rizzuto, Rosario, Mammucari, Cristina

Source: Cell death and differentiation. 26(2):362-381

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100103871357.0x000001&indx=1&recIds=ETOCvdc_100103871357.0x000001

Mapping Wnt/β-Catenin Signaling during Mouse Development and in Colorectal Tumors

Authors: Maretto, Silvia, Cordenonsi, Michelangelo, Dupont, Sirio, Braghetta, Paola, Broccoli, Vania, Hassan, A. Bassim, Volpin, Dino, Bressan, Giorgio M., Piccolo, Stefano

Source: Proceedings of the National Academy of Sciences of the United States of America, 2003 Mar . 100(6), 3299-3304.

Access URL: https://www.jstor.org/stable/3139353

Targeting Interleukin-1β Protects from Aortic Aneurysms Induced by Disrupted Transforming Growth Factor β Signaling

Authors: Da Ros, Francesco, Carnevale, Raimondo, Cifelli, Giuseppe, Bizzotto, Dario, Casaburo, Manuel, Perrotta, Marialuisa, Carnevale, Lorenzo, Vinciguerra, Iolanda, Fardella, Stefania, Iacobucci, Roberta, Bressan, Giorgio M., Braghetta, Paola, Lembo, Giuseppe, Carnevale, Daniela

Source: In Immunity 21 November 2017 47(5):959-973

Loss of EMILIN-1 Enhances Arteriolar Myogenic Tone Through TGF-β (Transforming Growth Factor-β)–Dependent Transactivation of EGFR (Epidermal Growth Factor Receptor) and Is Relevant for Hypertension in Mice and Humans

Authors: Carnevale, Daniela, Facchinello, Nicola, Iodice, Daniele, Bizzotto, Dario, Perrotta, Marialuisa, De Stefani, Diego, Pallante, Fabio, Carnevale, Lorenzo, Ricciardi, Franco, Cifelli, Giuseppe, Da Ros, Francesco, Casaburo, Manuel, Fardella, Stefania, Bonaldo, Paolo, Innocenzi, Gualtiero, Rizzuto, Rosario, Braghetta, Paola, Lembo, Giuseppe, Bressan, Giorgio M.

Source: Arteriosclerosis, thrombosis, and vascular biology. 38(10):2484-2497

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100067731314.0x000001&indx=1&recIds=ETOCvdc_100067731314.0x000001

The ablation of the matricellular protein EMILIN2 causes defective vascularization due to impaired EGFR-dependent IL-8 production affecting tumor growth

Authors: Paulitti, Alice, Andreuzzi, Eva, Bizzotto, Dario, Pellicani, Rosanna, Tarticchio, Giulia, Marastoni, Stefano, Pastrello, Chiara, Jurisica, Igor, Ligresti, Giovanni, Bucciotti, Francesco, Doliana, Roberto, Colladel, Roberta, Braghetta, Paola, Poletto, Evelina, Silvestre, Alessia, Bressan, Giorgio, Colombatti, Alfonso, Bonaldo, Paolo, Mongiat, Maurizio

Source: Oncogene. 37(25):3399-3414

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125087008.0x000001&indx=1&recIds=ETOCvdc_100125087008.0x000001

Distinct Regions Control Transcriptional Activation of the α1(VI) Collagen Promoter in Different Tissues of Transgenic Mice

Authors: Braghetta, Paola, Fabbro, Carla, Piccolo, Stefano, Marvulli, Donatella, Bonaldo, Paolo, Volpin, Dino, Bressan, Giorgio M.

Source: The Journal of Cell Biology, 1996 Nov 01. 135(4), 1163-1177.

Access URL: https://www.jstor.org/stable/1617768

GBA1 inactivation in oligodendrocytes affects myelination and induces neurodegenerative hallmarks and lipid dyshomeostasis in mice.

Authors: Gregorio, Ilaria, Russo, Loris, Torretta, Enrica, Barbacini, Pietro, Contarini, Gabriella, Pacinelli, Giada, Bizzotto, Dario, Moriggi, Manuela, Braghetta, Paola, Papaleo, Francesco, Gelfi, Cecilia, Moro, Enrico, Cescon, Matilde

Source: Molecular Neurodegeneration; 3/7/2024, Vol. 19 Issue 1, p1-25, 25p

Subject Terms: OLIGODENDROGLIA, MYELINATION, CENTRAL nervous system, HOMEOSTASIS, LYSOSOMAL storage diseases, PARKINSON'S disease, WESTERN immunoblotting