Functional screening identifies miRNAs with a novel function inhibiting vascular smooth muscle cell proliferation

Authors: Rodor, Julie ¹, Klimi, Eftychia ¹, Brown, Simon D. ¹, Krilis, Georgios ¹, Braga, Luca ², Ring, Nadja A.R. ², Ballantyne, Margaret D. ¹, Kesidou, Despoina ¹, Nguyen Dinh Cat, Aurelie ¹, Miscianinov, Vladislav ¹, Vacante, Francesca ¹, Miteva, Katarina ¹, Bennett, Matthew ¹, Beqqali, Abdelaziz ¹, Giacca, Mauro ^{3, 4}, Zacchigna, Serena ^{2, 4}, Baker, Andrew H. ^{1, 5, ∗}

Source: In Molecular Therapy 5 February 2025 33(2):615-630

Anti-miRNA therapeutics for uterine fibroids

Authors: Saxena, Sharad ^a, Volpe, Maria Concetta ^{a, b, c}, Agostinis, Chiara ^d, Vodret, Simone ^a, Ring, Nadja Anneliese Ruth ^{a, 1}, Colliva, Andrea ^a, Vuerich, Roman ^{a, c}, Braga, Luca ^b, Cook-Calvete, A. ^{a, 2}, Romano, Federico ^d, Zito, Gabriella ^d, Lorenzo, Giovanni Di ^d, Ura, Blendi ^d, Ricci, Giuseppe ^{d, e}, Pinamonti, Maurizio ^f, Bulla, Roberta ^c, Zacchigna, Serena ^{a, e, ⁎}

Source: In Biomedicine & Pharmacotherapy April 2025 185

Transbronchial lung cryobiopsy and pulmonary fibrosis: A never-ending story?

Authors: Ruaro, Barbara ^{a, ∗, 1}, Tavano, Stefano ^{a, 1}, Confalonieri, Paola ^a, Pozzan, Riccardo ^a, Hughes, Michael ^b, Braga, Luca ^c, Volpe, Maria Concetta ^c, Ligresti, Giovanni ^d, Andrisano, Alessia Giovanna ^a, Lerda, Selene ^e, Geri, Pietro ^a, Biolo, Marco ^a, Baratella, Elisa ^f, Confalonieri, Marco ^a, Salton, Francesco ^a

Source: In Heliyon April 2023 9(4)

Intercellular transfer of miR-200c-3p impairs the angiogenic capacity of cardiac endothelial cells

Authors: Ottaviani, Lara, Juni, Rio P., de Abreu, Ricardo C., Sansonetti, Marida, Sampaio-Pinto, Vasco, Halkein, Julie, Hegenbarth, Jana C., Ring, Nadja, Knoops, Kevin, Kocken, Jordy M.M., Jesus, Carlos de, Ernault, Auriane C., el Azzouzi, Hamid, Rühle, Frank, Olieslagers, Servé, Fernandes, Hugo, Ferreira, Lino, Braga, Luca, Stoll, Monika, Nascimento, Diana S., de Windt, Leon J., da Costa Martins, Paula A.

Source: Molecular therapy. 30(6):2257-2273

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167320129.0x000001&indx=1&recIds=ETOCvdc_100167320129.0x000001

Discovery platforms for RNA therapeutics.

Authors: Ciucci, Giulio¹ (AUTHOR), Braga, Luca² (AUTHOR), Zacchigna, Serena^1,3 (AUTHOR) zacchign@icgeb.org

Source: British Journal of Pharmacology. Jan2025, Vol. 182 Issue 2, p281-295. 15p.

Subject Terms: *DRUG discovery, *SMALL molecules, *RNA, *MOLECULES, *THERAPEUTICS

Deferoxamine mesylate improves splicing and GAA activity of the common c.-32-13T>G allele in late-onset PD patient fibroblasts

Authors: Buratti, Emanuele, Peruzzo, Paolo, Braga, Luca, Zanin, Irene, Stuani, Cristiana, Goina, Elisa, Romano, Maurizio, Giacca, Mauro, Dardis, Andrea

Source: In Molecular Therapy - Methods & Clinical Development 12 March 2021 20:227-236

Regenerative potential of epicardium-derived extracellular vesicles mediated by conserved miRNA transfer

Authors: del Campo, Cristina Villa, Liaw, Norman Y, Gunadasa-Rohling, Mala, Matthaei, Moritz, Braga, Luca, Kennedy, Tahnee, Salinas, Gabriela, Voigt, Niels, Giacca, Mauro, Zimmermann, Wolfram-Hubertus, Riley, Paul Richard

Source: Cardiovascular research. 118(2):597-611

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100139862578.0x000001&indx=1&recIds=ETOCvdc_100139862578.0x000001

Persistence of viral RNA, pneumocyte syncytia and thrombosis are hallmarks of advanced COVID-19 pathology

Authors: Bussani, Rossana, Schneider, Edoardo, Zentilin, Lorena, Collesi, Chiara, Ali, Hashim, Braga, Luca, Volpe, Maria Concetta, Colliva, Andrea, Zanconati, Fabrizio, Berlot, Giorgio, Silvestri, Furio, Zacchigna, Serena, Giacca, Mauro

Source: In EBioMedicine November 2020 61

17:15-17:25 Evaluation of Sars-CoV-2 entry receptors in COVID-19 positive and negative placentae: correlation between expression and infectivity

Authors: Agostinis, Chiara, Toffoli, Miriam, Spazzapan, Mariagiulia, Balduit, Andrea, Zito, Gabriella, Mangogna, Alessandro, Zupin, Luisa, Salviato, Tiziana, Braga, Luca, Maiocchi, Serena, Romano, Federico, Crovella, Sergio, Fontana, Francesco, Confalonieri, Marco, Ricci, Giuseppe, Bulla, Roberta

Source: Journal of reproductive immunology. 158

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196170778.0x000001&indx=1&recIds=ETOCvdc_100196170778.0x000001

Common Regulatory Pathways Mediate Activity of MicroRNAs Inducing Cardiomyocyte Proliferation

Authors: Torrini, Consuelo, Cubero, Ryan John, Dirkx, Ellen, Braga, Luca, Ali, Hashim, Prosdocimo, Giulia, Gutierrez, Maria Ines, Collesi, Chiara, Licastro, Danilo, Zentilin, Lorena, Mano, Miguel, Zacchigna, Serena, Vendruscolo, Michele, Marsili, Matteo, Samal, Areejit, Giacca, Mauro

Source: In Cell Reports 28 May 2019 27(9):2759-2771

Endothelial-to-mesenchymal transition enhances permissiveness to AAV vectors in cardiac endothelial cells

Authors: Volf, Nina, Vuerich, Roman, Colliva, Andrea, Volpe, Maria Concetta, Marengon, Margherita, Zentilin, Lorena, Giacca, Mauro, Ring, Nadja Anneliese Ruth, Vodret, Simone, Braga, Luca, Zacchigna, Serena

Source: Molecular Therapy; November 2024, Vol. 32 Issue: 11 p3808-3814, 7p

Endothelial cell–cardiomyocyte crosstalk in heart development and disease

Authors: Colliva, Andrea, Braga, Luca, Giacca, Mauro, Zacchigna, Serena

Source: Journal of physiology. 598(14):2923-2939

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107733019.0x000001&indx=1&recIds=ETOCvdc_100107733019.0x000001

Cardiac regeneration and remodelling of the cardiomyocyte cytoarchitecture

Authors: Ali, Hashim, Braga, Luca, Giacca, Mauro

Source: FEBS journal. 287(3):417-438

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100099810964.0x000001&indx=1&recIds=ETOCvdc_100099810964.0x000001

Non-coding RNA therapeutics for cardiac regeneration

Authors: Braga, Luca, Ali, Hashim, Secco, Ilaria, Giacca, Mauro

Source: Cardiovascular research. 117(3):674-693

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130286512.0x000001&indx=1&recIds=ETOCvdc_100130286512.0x000001

Emerin mislocalization during chromatin bridge resolution can drive prostate cancer cell invasiveness in a collagen-rich microenvironment.

Authors: Popęda, Marta, Kowalski, Kamil, Wenta, Tomasz, Beznoussenko, Galina V., Rychłowski, Michał, Mironov, Alexander, Lavagnino, Zeno, Barozzi, Sara, Richert, Julia, Bertolio, Rebecca, Myszczyński, Kamil, Szade, Jolanta, Bieńkowski, Michał, Miszewski, Kevin, Matuszewski, Marcin, Żaczek, Anna J., Braga, Luca, Del Sal, Giannino, Bednarz-Knoll, Natalia, Maiuri, Paolo

Source: Experimental & Molecular Medicine EMM; Sep2024, Vol. 56 Issue 9, p2016-2032, 17p

The Predictive and Prognostic Role of RAS–RAF–MEK–ERK Pathway Alterations in Breast Cancer: Revision of the Literature and Comparison with the Analysis of Cancer Genomic Datasets.

Authors: Rocca, Andrea¹ (AUTHOR) andrea.rocca@units.it, Braga, Luca² (AUTHOR), Volpe, Maria Concetta² (AUTHOR), Maiocchi, Serena² (AUTHOR), Generali, Daniele¹ (AUTHOR)

Source: Cancers. Nov2022, Vol. 14 Issue 21, p5306. 31p.

Subject Terms: *BREAST cancer prognosis, *BREAST tumor diagnosis, *PROTEINS, *DISEASE progression, *PREDICTIVE tests, *GENETIC mutation, *ONCOGENES, *CELLULAR signal transduction, *TRANSFERASES, *EPIGENOMICS, *DRUG resistance in cancer cells

MicroRNA therapy stimulates uncontrolled cardiac repair after myocardial infarction in pigs

Authors: Gabisonia, Khatia, Prosdocimo, Giulia, Aquaro, Giovanni, Carlucci, Lucia, Zentilin, Lorena, Secco, Ilaria, Ali, Hashim, Braga, Luca, Gorgodze, Nikoloz, Bernini, Fabio, Burchielli, Silvia, Collesi, Chiara, Zandonà, Lorenzo, Sinagra, Gianfranco, Piacenti, Marcello, Zacchigna, Serena, Bussani, Rossana, Recchia, Fabio, Giacca, Mauro

Source: Nature. 569(7756):418-422

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140045457.0x000001&indx=1&recIds=ETOCvdc_100140045457.0x000001

Cellular TRIM33 restrains HIV-1 infection by targeting viral integrase for proteasomal degradation

Authors: Ali, Hashim, Mano, Miguel, Braga, Luca, Naseem, Asma, Marini, Bruna, Vu, Diem, Collesi, Chiara, Meroni, Germana, Lusic, Marina, Giacca, Mauro

Source: Nature communications. 10(1):1-15

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100117616074.0x000001&indx=1&recIds=ETOCvdc_100117616074.0x000001

25-Hydroxycholesterol and inflammation in Lovastatin-deregulated mevalonate pathway

Authors: Tricarico, Paola Maura, Gratton, Rossella, Braga, Luca, Celsi, Fulvio, Crovella, Sergio

Source: In International Journal of Biochemistry and Cell Biology November 2017 92:26-33

A method for the detection of virus infectivity in single cells and real time: Towards an automated fluorescence neutralization test

Authors: Maistriau, Marylene, Carletti, Tea, Zakaria, Mohammad Khalid, Braga, Luca, Faoro, Valentina, Vasileiadis, Vasileios, Marcello, Alessandro

Source: VIRUS RESEARCH. 237:1-6

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100045223182.0x000001&indx=1&recIds=ETOCvdc_100045223182.0x000001