Molecular basis for substrate recruitment to the PRMT5 methylosome

Authors: Mulvaney, Kathleen M., Blomquist, Christa, Acharya, Nischal, Li, Ruitong, Ranaghan, Matthew J., O’Keefe, Meghan, Rodriguez, Diego J., Young, Michael J., Kesar, Devishi, Pal, Debjani, Stokes, Matthew, Nelson, Alissa J., Jain, Sidharth S., Yang, Annan, Mullin-Bernstein, Zachary, Columbus, Josie, Bozal, Fazli K., Skepner, Adam, Raymond, Donald, LaRussa, Salvatore, McKinney, David C., Freyzon, Yelena, Baidi, Yossef, Porter, Dale, Aguirre, Andrew J., Ianari, Alessandra, McMillan, Brian, Sellers, William R.

Source: In Molecular Cell 2 September 2021 81(17):3481-3495

Targeting Unc5b in macrophages drives atherosclerosis regression and pro-resolving immune cell function.

Authors: Schlegel, Martin, Cyr, Yannick, Newman, Alexandra A. C., Schreyer, Korbinian, Barcia Durán, José Gabriel, Sharma, Monika, Bozal, Fazli K., Gourvest, Morgane, La Forest, Maxwell, Afonso, Milessa S., van Solingen, Coen, Fisher, Edward A., Moore, Kathryn J.

Source: Proceedings of the National Academy of Sciences of the United States of America; 10/29/2024, Vol. 121 Issue 44, p1-11, 21p

Subject Terms: REGULATORY T cells, TH2 cells, ATHEROSCLEROTIC plaque, CELL populations, WESTERN diet

The IRG1-itaconate axis protects from cholesterol-induced inflammation and atherosclerosis.

Authors: Cyr, Yannick¹, Bozal, Fazli K.¹, Barcia Durán, José Gabriel¹, Newman, Alexandra A. C.¹, Amadori, Letizia¹, Smyrnis, Panagiotis¹, Gourvest, Morgane¹, Das, Dayasagar¹, Gildea, Michael¹, Kaur, Ravneet¹, Zhang, Tracy¹, Wang, Kristin M.¹, Von Itter, Richard¹, Schlegel, P. Martin², Dupuis, Samantha D.¹, Sanchez, Bernard F.¹, Schmidt, Ann Marie^1,3, Fisher, Edward A.^1,4, van Solingen, Coen¹, Giannarelli, Chiara^1,5

Source: Proceedings of the National Academy of Sciences of the United States of America. 4/9/2024, Vol. 121 Issue 15, p1-12. 30p.

Subject Terms: *MONONUCLEAR leukocytes, *ATHEROSCLEROSIS, *DRUG discovery, *THERAPEUTICS, *GLOBAL burden of disease

Suspension-based differentiation of adult mesenchymal stem cells toward chondrogenic lineage

Authors: Adeniran-Catlett, Adedayo E., Beguin, Estelle, Bozal, Fazli K., Murthy, Shashi K.

Source: Connective tissue research. 57(6):466-475

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100104576736.0x000001&indx=1&recIds=ETOCvdc_100104576736.0x000001

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Accelerated adipogenic differentiation of h MSCs in a microfluidic shear stimulation platform.

Authors: Adeniran‐Catlett, Adedayo E.¹, Weinstock, Laura D.², Bozal, Fazli K.², Beguin, Estelle³, Caraballo, Alexander T.³, Murthy, Shashi K.^3,4

Source: Biotechnology Progress; Mar/Apr2016, Vol. 32 Issue 2, p440-446, 7p