A p53-dependent translational program directs tissue-selective phenotypes in a model of ribosomopathies

Authors: Tiu, Gerald C., Kerr, Craig H., Forester, Craig M., Krishnarao, Pallavi S., Rosenblatt, Hannah D., Raj, Nitin, Lantz, Travis C., Zhulyn, Olena, Bowen, Margot E., Shokat, Leila, Attardi, Laura D., Ruggero, Davide, Barna, Maria

Source: In Developmental Cell 26 July 2021 56(14):2089-2102

Integrated K+ channel and K+Cl- cotransporter functions are required for the coordination of size and proportion during development

Authors: Lanni, Jennifer S., Peal, David, Ekstrom, Laura, Chen, Haining, Stanclift, Caroline, Bowen, Margot E., Mercado, Adriana, Gamba, Gerardo, Kahle, Kristopher T., Harris, Matthew P.

Source: In Developmental Biology 15 December 2019 456(2):164-178

The Spatiotemporal Pattern and Intensity of p53 Activation Dictates Phenotypic Diversity in p53-Driven Developmental Syndromes

Authors: Bowen, Margot E., McClendon, Jacob, Long, Hannah K., Sorayya, Aryo, Van Nostrand, Jeanine L., Wysocka, Joanna, Attardi, Laura D.

Source: In Developmental Cell 22 July 2019 50(2):212-228

Siva plays a critical role in mouse embryonic development

Authors: Jacobs, Suzanne B. R., Van Nostrand, Jeanine L., Bowen, Margot E., Baker, Julie C., Attardi, Laura D.

Source: Cell death and differentiation. 27(1):297-309

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193385640.0x000001&indx=1&recIds=ETOCvdc_100193385640.0x000001

Perspectives for identification of mutations in the zebrafish: Making use of next-generation sequencing technologies for forward genetic approaches

Authors: Henke, Katrin, Bowen, Margot E., Harris, Matthew P.

Source: In Methods 15 August 2013 62(3):185-196

An anterograde pathway for sensory axon degeneration gated by a cytoplasmic action of the transcriptional regulator P53

Authors: Simon, David J., Belsky, Deanna M., Bowen, Margot E., Ohn, Christine Y.J., O’Rourke, Melanie K., Shen, Rebecca, Kim, Garam, Pitts, Jason, Attardi, Laura D., Tessier-Lavigne, Marc

Source: In Developmental Cell 5 April 2021 56(7):976-984

SHP2 Regulates Chondrocyte Terminal Differentiation, Growth Plate Architecture and Skeletal Cell Fates.

Authors: Bowen, Margot E.¹, Ayturk, Ugur M.¹ matthew.warman@childrens.harvard.edu, Kurek, Kyle C.¹, Yang, Wentian², Warman, Matthew L.¹

Source: PLoS Genetics. May2014, Vol. 10 Issue 5, p1-16. 16p.

Subject Terms: *CARTILAGE cells, *EXOSTOSIS, *CHONDROGENESIS, *FIBROBLASTS, *ENCHONDROMA, *BONE cells

Efficient Mapping and Cloning of Mutations in Zebrafish by Low-Coverage Whole-Genome Sequencing.

Authors: Bowen, Margot E.^1,2, Henke, Katrin^1,2, Siegfried, Kellee R.¹, Warman, Matthew L.¹, Harris, Matthew P.^1,2, harris@genetics.med.harvard.edu

Source: Genetics; Mar2012, Vol. 190 Issue 3, p1017-1024, 16p

Loss-of-Function Mutations in PTPN11 Cause Metachondromatosis, but Not Ollier Disease or Maffucci Syndrome.

Authors: Bowen, Margot E., Boyden, Eric D., Holm, Ingrid A., Campos-Xavier, Belinda, Bonafé, Luisa, Superti-Furga, Andrea, Ikegawa, Shiro, Cormier-Daire, Valerie, Bov´e, Judith V., Pansuriya, Twinkal C., de Sousa, Sérgio B., Savarirayan, Ravi, Andreucci, Elena, Vikkula, Miikka, Garavelli, Livia, Pottinger, Caroline, Ogino, Toshihiko, Sakai, Akinori, Regazzoni, Bianca M., Wuyts, Wim

Source: PLoS Genetics. Apr2011, Vol. 7 Issue 4, p1-11. 11p.

Subject Terms: *GENETIC mutation, *ENCHONDROMATOSIS, *ETIOLOGY of diseases, *EXOSTOSIS, *GENE targeting, *NUCLEOTIDE sequence, *EXONS (Genetics)

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Puma- and Caspase9-mediated apoptosis is dispensable for p53-driven neural crest-based developmental defects

Authors: Bowen, Margot E., Mulligan, Abigail S., Sorayya, Aryo, Attardi, Laura D.

Source: Cell Death and Differentiation; July 2021, Vol. 28 Issue: 7 p2083-2094, 12p

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The role of p53 in developmental syndromes.

Authors: Bowen, Margot E, Attardi, Laura D

Source: Journal of Molecular Cell Biology; Mar2019, Vol. 11 Issue 3, p200-211, 12p

Somatic Mosaic Activating Mutations in PIK3CA Cause CLOVES Syndrome

Authors: Kurek, Kyle C., Luks, Valerie L., Ayturk, Ugur M., Alomari, Ahmad I., Fishman, Steven J., Spencer, Samantha A., Mulliken, John B., Bowen, Margot E., Yamamoto, Guilherme L., Kozakewich, Harry P.W., Warman, Matthew L.

Source: In The American Journal of Human Genetics 8 June 2012 90(6):1108-1115

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Identification of Mutations in Zebrafish Using Next‐Generation Sequencing

Authors: Henke, Katrin, Bowen, Margot E., Harris, Matthew P.

Source: Current protocols in molecular biology; October 2013, Vol. 104 Issue: 1 p7.13.1-7.13.33