Midostaurin shapes macroclonal and microclonal evolution of FLT3-mutated acute myeloid leukemia

Authors: Joudinaud, Romane ^{1, 2}, Boudry, Augustin ^{2, 3}, Fenwarth, Laurène ^{1, 2}, Geffroy, Sandrine ^{1, 2}, Salson, Mikaël ⁴, Dombret, Hervé ⁵, Berthon, Céline ^{1, 6}, Pigneux, Arnaud ⁷, Lebon, Delphine ⁸, Peterlin, Pierre ⁹, Bouzy, Simon ¹⁰, Flandrin-Gresta, Pascale ¹¹, Tavernier, Emmanuelle ¹², Carre, Martin ¹³, Tondeur, Sylvie ¹⁴, Haddaoui, Lamya ¹⁵, Itzykson, Raphael ^{5, 16}, Bertoli, Sarah ¹⁷, Bidet, Audrey ¹⁸, Delabesse, Eric ¹⁹, Hunault, Mathilde ²⁰, Récher, Christian ¹⁷, Preudhomme, Claude ^{1, 2}, Duployez, Nicolas ^{1, 2}, Dumas, Pierre-Yves ^{7, ∗}

Source: In Blood Advances 28 January 2025 9(2):365-374

CPX-351 in higher risk myelodysplastic syndrome and chronic myelomonocytic leukaemia: a multicentre, single-arm, phase 2 study

Authors: Peterlin, Pierre ^*, Le Bris, Yannick, Turlure, Pascal, Chevallier, Patrice, Ménard, Audrey, Gourin, Marie-Pierre, Dumas, Pierre-Yves, Thepot, Sylvain, Berceanu, Ana, Park, Sophie, Hospital, Marie-Anne, Cluzeau, Thomas, Bouzy, Simon, Torregrosa-Diaz, Jose-Miguel, Drevon, Louis, Sapena, Rosa, Chermat, Fatiha, Ades, Lionel, Dimicoli-Salazar, Sophie, Chevret, Sylvie, Béné, Marie-Christine, Fenaux, Pierre

Source: In The Lancet Haematology July 2023 10(7):e521-e529

Genetic characterization of B-cell prolymphocytic leukemia: a prognostic model involving MYC and TP53

Authors: Chapiro, Elise, Pramil, Elodie, Diop, M'boyba, Roos-Weil, Damien, Dillard, Clémentine, Gabillaud, Clémentine, Maloum, Karim, Settegrana, Catherine, Baseggio, Lucile, Lesesve, Jean-François, Yon, Mélanie, Jondreville, Ludovic, Lesty, Claude, Davi, Frédéric, Le Garff-Tavernier, Magali, Droin, Nathalie, Dessen, Philippe, Algrin, Caroline, Leblond, Véronique, Gabarre, Jean, Bouzy, Simon, Eclache, Virginie, Gaillard, Baptiste, Callet-Bauchu, Evelyne, Muller, Marc, Lefebvre, Christine, Nadal, Nathalie, Ittel, Antoine, Struski, Stéphanie, Collonge-Rame, Marie-Agnès, Quilichini, Benoit, Fert-Ferrer, Sandra, Auger, Nathalie, Radford-Weiss, Isabelle, Wagner, Lena, Scheinost, Sebastian, Zenz, Thorsten, Susin, Santos A., Bernard, Olivier A., Nguyen-Khac, Florence

Source: In Blood 21 November 2019 134(21):1821-1831

Gain of the short arm of chromosome 2 (2p gain) has a significant role in drug‐resistant chronic lymphocytic leukemia

Authors: Kostopoulou, Fotini, Gabillaud, Clementine, Chapiro, Elise, Grange, Beatrice, Tran, Julie, Bouzy, Simon, Degaud, Michael, Ghamlouch, Hussein, Le Garff‐Tavernier, Magali, Maloum, Karim, Choquet, Sylvain, Leblond, Veronique, Gabarre, Jean, Lavaud, Anne, Morel, Veronique, Roos‐Weil, Damien, Uzunov, Madalina, Guieze, Romain, Bernard, Olivier A., Susin, Santos A., Tournilhac, Olivier, Nguyen‐Khac, Florence

Source: Cancer medicine. 8(6):3131-3141

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100087201880.0x000001&indx=1&recIds=ETOCvdc_100087201880.0x000001

Lineage switch and relapse in sanctuary site: Some lessons to learn about plasticity in KMT2Ar acute leukemia

Authors: Le Calvez, Baptiste, Rialland, Fanny, Bassi, Corentin, Richard, Camille, Chucherko, Kevin, Bouzy, Simon, Le Bris, Yannick, Theisen, Olivier, Béné, Marie C, Grain, Audrey, Eveillard, Marion

Source: Pediatric blood & cancer. 69(10)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100158997838.0x000001&indx=1&recIds=ETOCvdc_100158997838.0x000001

Phase I study of zoledronic acid combined with escalated doses of interleukine‐2 for early in vivo generation of Vγ9Vδ2 T‐cells after haploidentical stem cell transplant with posttransplant cyclophosphamide.

Authors: Jullien, Maxime, Guillaume, Thierry, Le Bourgeois, Amandine, Peterlin, Pierre, Garnier, Alice, Eveillard, Marion, Le Bris, Yannick, Bouzy, Simon, Tessoulin, Benoît, Gastinne, Thomas, Dubruille, Viviane, Touzeau, Cyrille, Mahé, Béatrice, Blin, Nicolas, Lok, Anne, Vantyghem, Sophie, Sortais, Clara, Antier, Chloé, Moreau, Philippe, Scotet, Emmanuel

Source: American Journal of Hematology; Mar2024, Vol. 99 Issue 3, p350-359, 10p

Molecular Response Analysis By High Throughput Sequencing in Higher Risk Myelodysplastic Syndrome (HR-MDS) Treated Intensively with CPX-351

Authors: Le Bris, Yannick ^*, Bouzy, Simon ^*, Ménard, Audrey ^*, Turlure, Pascal ^*, Chevallier, Patrice, Gourin, Marie-Pierre ^*, Dumas, Pierre-Yves ^*, Thepot, Sylvain ^*, Berceanu, Anna ^*, Park, Sophie, Hospital, Marie-Anne ^*, Cluzeau, Thomas ^*, Torregrosa Diaz, Jose-Miguel ^*, Devron, Louis ^*, Sapena, Rosa ^*, Chermat, Fatiha ^*, Dimicoli Salazar, Sophie ^*, Béné, Marie C ^*, Fenaux, Pierre, Peterlin, Pierre ^*

Source: In Blood 15 November 2022 140 Supplement 1:9821-9823

Vacuoles, E1 enzyme, X-linked, autoinflammatory, and somatic syndrome in the intensive care unit: a case report.

Authors: Belicard, Félicie, Belhomme, Nicolas, Bouzy, Simon, Saillard, Clémence, Nedelec, Fabienne, Mear, Jean-Baptiste, Ardois, Samuel, Pastoret, Cedric, Reizine, Florian, Camus, Christophe, Painvin, Benoit

Source: Journal of Medical Case Reports; 7/22/2023, Vol. 17 Issue 1, p1-7, 7p

Subject Terms: INTENSIVE care units, SWEET'S syndrome, VENOUS thrombosis, SYNDROMES, PURE red cell aplasia, THROMBOEMBOLISM, PANCYTOPENIA

Neonatal diagnosis of congenital dyserythropoietic anemia type II.

Authors: Lelard, Apolline, Le Calvez, Baptiste, Bouzy, Simon, Couec, Marie Laure, Eveillard, Marion

Source: International Journal of Laboratory Hematology; Oct2024, Vol. 46 Issue 5, p764-765, 2p

Subject Terms: DIAGNOSIS of blood diseases, CONGENITAL hemolytic anemia, CYTOLOGY, BONE marrow examination, HEMOGLOBINS, ELECTROPHORESIS, HEMOLYSIS & hemolysins, BLOOD diseases, RETICULOCYTES, CHILDREN

Optical Genome Mapping Combined with High-Throughput Sequencing Is Effective for the Diagnostic and Prognostic Genomic Classification of Acute Myeloid Leukemia and Myelodysplastic Neoplasms

Authors: LE Bris, Yannick, Madeuf, Romain, Godon, Catherine, Pichon, Olivier, Peterlin, Pierre, Garnier, Alice, Chevallier, Patrice, Bouzy, Simon, Eveillard, Marion, Béné, Marie-Christine, Theisen, Olivier, vasheghani Farahani, Faeseh

Source: In Blood 2 November 2023 142 Supplement 1:6051-6051

Deep Learning Based Blood Abnormalities Detection As a Tool for Vexas Syndrome Screening

Authors: De Almeida Braga, Cedric, Bauvais, Maxence, Sujobert, Pierre, Heiblig, Mael, Jullien, Maxime, Le Calvez, Baptiste, Richard, Camille, Le Roc'h, Valentin, Rault, Emmanuelle, Herault, Olivier, Peterlin, Pierre, Garnier, Alice, Chevallier, Patrice, Bouzy, Simon, LE Bris, Yannick, Neel, Antoine, Graveleau, Julie, Paul-Gilloteaux, Perrine, Kosmider, Olivier, Normand, Nicolas, Eveillard, Marion

Source: In Blood 2 November 2023 142 Supplement 1:3648-3648

Artificial Intelligence Using Multimodal Data for Myelodysplastic Syndrome Screening

Authors: De almeida Braga, Cedric ^*, Bauvais, Maxence ^*, Dominici, Maxence ^*, Garnier, Alice ^*, Peterlin, Pierre ^*, Debord, Camille ^*, Wuillème, Soraya ^*, Theisen, Olivier ^*, Godon, Catherine ^*, Bouzy, Simon ^*, Le Bris, Yannick ^*, Bene, Marie C ^*, Chevallier, Patrice, Normand, Nicolas ^*, Eveillard, Marion ^*

Source: In Blood 15 November 2022 140 Supplement 1:9800-9801

Vexas Syndrome: A Complex Necessarily Integrated Diagnosis That Can Benefit from the Help of Deep Learning

Authors: De almeida Braga, Cedric ^*, Richard, Camille ^*, Le Calvez, Baptiste ^*, Chevallier, Patrice, Bouzy, Simon ^*, Le Bris, Yannick ^*, Garnier, Alice ^*, Peterlin, Pierre ^*, Béné, Marie C ^*, Normand, Nicolas ^*, Eveillard, Marion ^*

Source: In Blood 15 November 2022 140 Supplement 1:13025-13026

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Treatment CLL: Impact in the Dynamic of Clonal Evolution

Authors: Bouzy, Simon, Armand, Marine, Gabillaud, Clementine, Chapiro, Elise, Bougacha, Nadia, Kostopoulou, Fotini, Davi, Frederic, Le Garff-Tavernier, Magali, Maloum, Karim, Leblond, Veronique, Morel, Veronique, Roos-Weil, Damien, Lavaud, Anne, Gabarre, Jean, Sylvain, Choquet, Susin, Santos, Bernard, Olivier, Nguyen-Khac, Florence

Source: Clinical lymphoma, myeloma & leukemia. 18(S1):S219-S219

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100069649561.0x000001&indx=1&recIds=ETOCvdc_100069649561.0x000001

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Genetic characterization of B-cell prolymphocytic leukemia: a prognostic model involving MYCand TP53

Authors: Chapiro, Elise, Pramil, Elodie, Diop, M'boyba, Roos-Weil, Damien, Dillard, Clémentine, Gabillaud, Clémentine, Maloum, Karim, Settegrana, Catherine, Baseggio, Lucile, Lesesve, Jean-François, Yon, Mélanie, Jondreville, Ludovic, Lesty, Claude, Davi, Frédéric, Le Garff-Tavernier, Magali, Droin, Nathalie, Dessen, Philippe, Algrin, Caroline, Leblond, Véronique, Gabarre, Jean, Bouzy, Simon, Eclache, Virginie, Gaillard, Baptiste, Callet-Bauchu, Evelyne, Muller, Marc, Lefebvre, Christine, Nadal, Nathalie, Ittel, Antoine, Struski, Stéphanie, Collonge-Rame, Marie-Agnès, Quilichini, Benoit, Fert-Ferrer, Sandra, Auger, Nathalie, Radford-Weiss, Isabelle, Wagner, Lena, Scheinost, Sebastian, Zenz, Thorsten, Susin, Santos A., Bernard, Olivier A., Nguyen-Khac, Florence

Source: Blood; November 2019, Vol. 134 Issue: 21 p1821-1831, 11p

Clonal Evolution in CLL

Authors: Bouzy, Simon, Armand, Marine ^*, Gabillaud, Clementine ^*, Chapiro, Elise ^*, Bougacha, Nadia ^*, Kostopoulou, Fotini ^*, Davi, Frederic ^*, Le Garff-Tavernier, Magali ^*, Maloum, Karim ^*, Leblond, Veronique, Morel, Veronique ^*, Roos-Weil, Damien ^*, Lavaud, Anne ^*, Gabarre, Jean ^*, Sylvain, Choquet ^*, Susin, Santos ^*, Bernard, Olivier ^*, Nguyen-Khac, Florence ^*

Source: In Blood 8 December 2017 130 Supplement 1:3008-3008

The Gain of the Short Arm of Chromosome 2 (2pgain) Plays an Important Role in CLL Drug Resistance, and Has to be Systematically Considered before Deciding an Adapted Therapy

Authors: Kostopoulou, Fotini ^*, Bougacha, Nadia ^*, Gabillaud, Clementine ^*, Chapiro, Elise ^*, Bouzy, Simon, Le Garff-Tavernier, Magali ^*, Maloum, Karim ^*, Sylvain, Choquet ^*, Leblond, Veronique, Gabarre, Jean ^*, Lavaud, Anne ^*, Morel, Veronique ^*, Roos-Weil, Damien ^*, Uzunov, Madalina ^*, Guieze, Romain ^*, Tournilhac, Olivier ^*, Susin, Santos ^*, Bernard, Olivier ^*, Nguyen-Khac, Florence ^*

Source: In Blood 8 December 2017 130 Supplement 1:1729-1729

Deep Learning‐Based Blood Abnormalities Detection as a Tool for VEXAS Syndrome Screening.

Authors: De Almeida Braga, Cédric¹ (AUTHOR), Bauvais, Maxence² (AUTHOR), Sujobert, Pierre³ (AUTHOR), Heiblig, Maël⁴ (AUTHOR), Jullien, Maxime⁵ (AUTHOR), Le Calvez, Baptiste⁵ (AUTHOR), Richard, Camille² (AUTHOR), Le Roc'h, Valentin² (AUTHOR), Rault, Emmanuelle⁶ (AUTHOR), Hérault, Olivier⁶ (AUTHOR), Peterlin, Pierre⁷ (AUTHOR), Garnier, Alice⁷ (AUTHOR), Chevallier, Patrice^5,7 (AUTHOR), Bouzy, Simon² (AUTHOR), Le Bris, Yannick^2,3 (AUTHOR), Néel, Antoine⁸ (AUTHOR), Graveleau, Julie⁹ (AUTHOR), Kosmider, Olivier¹⁰ (AUTHOR), Paul‐Gilloteaux, Perrine¹¹ (AUTHOR), Normand, Nicolas¹ (AUTHOR)

Source: International Journal of Laboratory Hematology. Sep2024, p1. 10p. 5 Illustrations.

Subject Terms: *CONVOLUTIONAL neural networks, *MACHINE learning, *DEEP learning, *ARTIFICIAL intelligence, *MEDICAL screening