Magnetic bead-sensitized optoporation coupled with antibodies-based activation for mRNA CAR-T cell manufacturing

Authors: Maldonado-Pérez, Noelia ^{1, 2}, Doucey, Marie-Agnès ⁵, Dzhumashev, Dzhangar ^{1, 2}, Martínez Bedoya, Darel ^{1, 2}, Castillo Cantero, Luis ^{1, 2}, Boudousquie, Caroline ⁵, Pierson, Yann ⁵, Henry, Luc ⁵, Dutoit, Valérie ^{1, 2}, Migliorini, Denis ^{1, 2, 3, 4, ∗}

Source: In Molecular Therapy - Methods & Clinical Development 13 March 2025 33(1)

Development of an optimized closed and semi-automatic protocol for Good Manufacturing Practice manufacturing of tumor-infiltrating lymphocytes in a hospital environment

Authors: Gannon, Philippe O. ^*, Harari, Alexandre ^*, Auger, Aymeric, Murgues, Clément, Zangiacomi, Vincent, Rubin, Olivier, Ellefsen Lavoie, Kim, Guillemot, Laurent, Navarro Rodrigo, Blanca, Nguyen-Ngoc, Tu, Rusakiewicz, Sylvie, Rossier, Laetitia, Boudousquié, Caroline, Baumgaertner, Petra, Zimmermann, Stefan, Trueb, Lionel, Iancu, Emanuela M., Sempoux, Christine, Demartines, Nicolas, Coukos, George, Kandalaft, Lana E.

Source: In Cytotherapy December 2020 22(12):780-791

Are dendritic cells the most appropriate therapeutic vaccine for patients with ovarian cancer?

Authors: Martin-Lluesma, Silvia, Graciotti, Michele, Grimm, Alizée J, Boudousquié, Caroline, Chiang, Cheryl L, Kandalaft, Lana E

Source: In Current Opinion in Biotechnology October 2020 65:190-196

MicroRNA-155 Is Required for Effector CD8+ T Cell Responses to Virus Infection and Cancer

Authors: Dudda, Jan C., Salaun, Bruno, Ji, Yun, Palmer, Douglas C., Monnot, Gwennaelle C., Merck, Estelle, Boudousquie, Caroline, Utzschneider, Daniel T., Escobar, Thelma M., Perret, Rachel, Muljo, Stefan A., Hebeisen, Michael, Rufer, Nathalie, Zehn, Dietmar, Donda, Alena, Restifo, Nicholas P., Held, Werner, Gattinoni, Luca, Romero, Pedro

Source: In Immunity 18 April 2013 38(4):742-753

Essential role of the Wnt pathway effector Tcf-1 for the establishment of functional CD8 T cell memory

Authors: Jeannet, Grégoire, Boudousquié, Caroline, Gardiol, Noémie, Kang, Joonsoo, Huelsken, Joerg, Held, Werner, Fearon, Douglas T.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2010 May . 107(21), 9777-9782.

Access URL: https://www.jstor.org/stable/25681676

Polyfunctional response by Imm TAC ( IMCgp100) redirected CD8⁺ and CD4⁺ T cells.

Authors: Boudousquie, Caroline¹, Bossi, Giovanna¹, Hurst, Jacob M.¹, Rygiel, Karolina A.¹, Jakobsen, Bent K.¹, Hassan, Namir J.¹ Namir.Hassan@immunocore.com

Source: Immunology. Nov2017, Vol. 152 Issue 3, p425-438. 14p.

Subject Terms: *T cell receptors, *IMMUNE response, *HLA histocompatibility antigens, *CANCER immunotherapy, *INTERFERONS

A Phase Ib Study of the Combination of Personalized Autologous Dendritic Cell Vaccine, Aspirin, and Standard of Care Adjuvant Chemotherapy Followed by Nivolumab for Resected Pancreatic Adenocarcinoma—A Proof of Antigen Discovery Feasibility in Three Patients

Authors: Bassani-Sternberg, Michal, Digklia, Antonia, Huber, Florian, Wagner, Dorothea, Sempoux, Christine, Stevenson, Brian J., Thierry, Anne-Christine, Michaux, Justine, Pak, HuiSong, Racle, Julien, Boudousquie, Caroline, Balint, Klara, Coukos, George, Gfeller, David, Martin Lluesma, Silvia, Harari, Alexandre, Demartines, Nicolas, Kandalaft, Lana E.

Source: Frontiers in Immunology; 8/8/2019, p1-17, 17p

Subject Terms: DENDRITIC cells, ADJUVANT treatment of cancer, VACCINES

Personalized Dendritic Cell Vaccines—Recent Breakthroughs and Encouraging Clinical Results.

Authors: Mastelic-Gavillet, Beatris, Balint, Klara, Boudousquie, Caroline, Gannon, Philippe O., Kandalaft, Lana E.

Source: Frontiers in Immunology; 4/11/2019, pN.PAG-N.PAG, 10p

Subject Terms: DENDRITIC cells, CANCER immunotherapy, CANCER vaccines, IMMUNE system, ANTINEOPLASTIC agents

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A Personalized Neoantigen Vaccine in Combination with Platinum-Based Chemotherapy Induces a T-Cell Response Coinciding with a Complete Response in Endometrial Carcinoma.

Authors: Harari, Alexandre, Sarivalasis, Apostolos, de Jonge, Kaat, Thierry, Anne-Christine, Huber, Florian, Boudousquie, Caroline, Rossier, Laetitia, Orcurto, Angela, Imbimbo, Martina, Baumgaertner, Petra, Bassani-Sternberg, Michal, Kandalaft, Lana E.

Source: Cancers; Nov2021, Vol. 13 Issue 22, p5801, 1p

Subject Terms: PLATINUM compounds, DENDRITIC cells, GENETIC mutation, CANCER chemotherapy, ONCOGENES, INDIVIDUALIZED medicine, CANCER relapse, TREATMENT effectiveness, ENDOMETRIAL tumors, CANCER vaccines, T cells, IMMUNOTHERAPY, ANTIGENS

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