Determination of the Plasma Protein Binding of Liraglutide Using the EScalate* Equilibrium Shift Assay

Authors: Ungewiss, Jan, Gericke, Seike, Boriss, Hinnerk

Source: In Journal of Pharmaceutical Sciences March 2019 108(3):1309-1314

Intracellular Drug Bioavailability: Effect of Neutral Lipids and Phospholipids

Authors: Treyer, Andrea, Mateus, André, Wiśniewski, Jacek R., Boriss, Hinnerk, Matsson, Pär, Artursson, Per

Source: Molecular pharmaceutics. 15(6):2224-2233

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN616278883&indx=1&recIds=ETOCRN616278883

Brain Tissue Binding of Drugs: Evaluation and Validation of Solid Supported Porcine Brain Membrane Vesicles (TRANSIL) as a Novel High-Throughput Method

Authors: Longhi, Raffaele ^*, Corbioli, Silvia, Fontana, Stefano, Vinco, Federicia, Braggio, Simone, Helmdach, Lydia, Schiller, Jürgen, Boriss, Hinnerk

Source: In Drug Metabolism and Disposition February 2011 39(2):312-321

A Cell-Free Approach Based on Phospholipid Characterization for Determination of the Cell Specific Unbound Drug Fraction (fu, cell)

Authors: Treyer, Andrea, Walday, Sandra, Boriss, Hinnerk, Matsson, Pär, Artursson, Per

Source: PHARMACEUTICAL RESEARCH. 36(12)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100129428157.0x000001&indx=1&recIds=ETOCvdc_100129428157.0x000001

DETERMINATION AND ESTIMATION OF ABSORPTION AND DISTRIBUTION OF SUBSTANCES IN BRAIN TISSUE

Purification and characterization of phosphoglucose isomerase allozymes from Daphnia magna

Authors: Boriss, Hinnerk ^*

Source: In Biochimie 2001 83(10):979-984

Brain Availability Is the Key Parameter for Optimising the Permeability of Central Nervous System Drugs.

Authors: Boriss, Hinnerk¹ hbo@sovicell.com

Source: Drug Discovery. 2010, Vol. 7, p58-62. 4p.

Subject Terms: *EFFECT of drugs on the brain, *CENTRAL nervous system stimulants, *DRUG absorption, *PERMEABILITY (Biology), *BLOOD-brain barrier, *PARTITION coefficient (Chemistry), *PHARMACODYNAMICS

Meta-analysis of microarray data on pancreatic cancer defines a set of commonly dysregulated genes.

Authors: Grützmann, Robert¹, Boriss, Hinnerk², Ammerpohl, Ole³, Lüttges, Jutta⁴, Kalthoff, Holger³, Schackert, Hans Konrad⁵, Klöppel, Günter⁴, Saeger, Hans Detlev¹, Pilarsky, Christian¹ Christian.pilarsky@mailbox.tu-dresden.de

Source: Oncogene. 7/28/2005, Vol. 24 Issue 32, p5079-5088. 10p.

Subject Terms: *META-analysis, *PANCREATIC diseases, *CANCER, *MEMBRANE fusion, *IMMUNOHISTOCHEMISTRY, *GENE expression

TRAC: A novel gene expression quantification method – Compared to QPCR

Authors: Boriss, Hinnerk, Rossignolo, Francesco, Fontana, Stefano, Salmivaara, Jani, Kivela, Oona

Source: In Drug Metabolism and Pharmacokinetics January 2018 33(1) Supplement:S51-S51

Measuring plasma protein binding of liraglutide using the escalate assay

Authors: Boriss, Hinnerk

Source: In Drug Metabolism and Pharmacokinetics January 2018 33(1) Supplement:S24-S24

Differentially expressed cortical genes contribute to perivascular deposition in transgenic mice with inducible neuron-specific expression of TGF-β1

Authors: Ueberham, Uwe, Zobiak, Bernd, Ueberham, Elke, Brückner, Martina K., Boriss, Hinnerk, Arendt, Thomas

Source: International Journal of Developmental Neuroscience; Apr2006, Vol. 24 Issue 2/3, p177-186, 10p

Subject Terms: TRANSFORMING growth factors, GENE expression, TRANSGENIC mice, NEUROBIOLOGY

EXPRESSION PROFILING: TOWARD AN APPLICATION IN SEPSIS DIAGNOSTICS.

Authors: Prucha, Miroslav, Ruryk, Andriy, Boriss, Hinnerk, Möller, Eva, Zazula, Roman, Herold, Ivan, Claus, Ralf A, Reinhart, Konrad A, Deigner, Peter, Russwurm, Stefan

Source: Shock; Jul2004, Vol. 22 Issue 1, p29-33, 5p

Seasonal isotopic shifts in fish of the Pantanal wetland, Brazil.

Authors: Wantzen, Karl M., de Arruda Machado, Francisco, Voss, Maren, Boriss, Hinnerk, Junk, Wolfgang J.

Source: Aquatic Sciences; Oct2002, Vol. 64 Issue 3, p239-251, 13p

Does trimethylamine induce life-history reactions in Daphnia?

Authors: Lass, Sandra, Boersma, Maarten, Wiltshire, Karen Helen, Spaak, Piet, Boriss, Hinnerk

Source: Hydrobiologia; Jan2001, Vol. 442 Issue 1-3, p199, 8p, 3 Charts, 8 Graphs

Subject Terms: DAPHNIA, LIFE cycles (Biology), BEHAVIOR

Maternal effects after sexual reproduction in Daphnia magna.

Authors: Boersma, Maarten, Boriss, Hinnerk, Mitchell, Suzanne E.

Source: Journal of Plankton Research; Feb2000, Vol. 22 Issue 2, p279-285, 7p, 1 Chart, 1 Graph

Subject Terms: DAPHNIA magna, EGG incubation, PROBABILITY theory, PREDATION, COPEPODA

Trimethylamine induces migration of waterfleas.

Authors: Boriss, Hinnerk, Boersma, Maarten, Wiltshire, Karen H.

Source: Nature; April 1 1999, Vol. 398 Issue 6726, p382-382, 1p

A Cell-Free Approach Based on Phospholipid Characterization for Determination of the Cell Specific Unbound Drug Fraction (fu,cell).

Authors: Treyer, Andrea, Walday, Sandra, Boriss, Hinnerk, Matsson, Pär, Artursson, Per

Source: Pharmaceutical Research; Dec2019, Vol. 36 Issue 12, pN.PAG-N.PAG, 1p, 5 Graphs

Subject Terms: CELL determination, CELL compartmentation, PHOSPHOLIPIDS, CELL anatomy, CELL membranes, SUBSPECIES, BILAYER lipid membranes

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