Ketogenic diet administration later in life improves memory by modifying the synaptic cortical proteome via the PKA signaling pathway in aging mice

Authors: Acuña-Catalán, Diego, Shah, Samah, Wehrfritz, Cameron, Nomura, Mitsunori, Acevedo, Alejandro, Olmos, Cristina, Quiroz, Gabriel, Huerta, Hernán, Bons, Joanna, Ampuero, Estibaliz, Wyneken, Ursula, Sanhueza, Magdalena, Arancibia, Felipe, Contreras, Darwin, Cárdenas, Julio César, Morales, Bernardo, Schilling, Birgit, Newman, John C., González-Billault, Christian

Source: In Cell Reports Medicine 18 June 2024 5(6)

Brain transcriptomic, metabolic and mitohormesis properties associated with N-propargylglycine treatment: A prevention strategy against neurodegeneration

Authors: Teramayi, Fadzai, Bons, Joanna, Scott, Madeleine, Scott, Gary K., Loureiro, Ashley, Lopez-Ramirez, Alejandro, Schilling, Birgit, Ellerby, Lisa M., Benz, Christopher C.

Source: In Brain Research 1 March 2024 1826

Extracellular Matrix Orchestration of Tissue Remodeling in the Chronically Inflamed Mouse Colon

Authors: Moutin, Elisa B., Bons, Joanna, Giavara, Giada, Lourenco, Filipe, Pan, Deng, Burton, Jordan B., Shah, Samah, Colombé, Mathilde, Gascard, Philippe, Tlsty, Thea, Schilling, Birgit, Winton, Douglas J.

Source: In Cellular and Molecular Gastroenterology and Hepatology 2024 17(4):639-656

Proteomic analysis of X-linked dystonia parkinsonism disease striatal neurons reveals altered RNA metabolism and splicing

Authors: Tshilenge, Kizito-Tshitoko, Bons, Joanna, Aguirre, Carlos Galicia, Geronimo-Olvera, Cristian, Shah, Samah, Rose, Jacob, Gerencser, Akos A., Mak, Sally K., Ehrlich, Michelle E., Bragg, D. Cristopher, Schilling, Birgit, Ellerby, Lisa M.

Source: In Neurobiology of Disease January 2024 190

Ketohexokinase-C regulates global protein acetylation to decrease carnitine palmitoyltransferase 1a-mediated fatty acid oxidation

Authors: Helsley, Robert N., Park, Se-Hyung, Vekaria, Hemendra J., Sullivan, Patrick G., Conroy, Lindsey R., Sun, Ramon C., Romero, María del Mar, Herrero, Laura, Bons, Joanna, King, Christina D., Rose, Jacob, Meyer, Jesse G., Schilling, Birgit, Kahn, C. Ronald, Softic, Samir

Source: Journal of hepatology. 79(1):25-42

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100192577090.0x000001&indx=1&recIds=ETOCvdc_100192577090.0x000001

Fructose induced KHK-C can increase ER stress independent of its effect on lipogenesis to drive liver disease in diet-induced and genetic models of NAFLD

Authors: Park, Se-Hyung, Helsley, Robert N., Fadhul, Taghreed, Willoughby, Jennifer L.S., Noetzli, Leila, Tu, Ho-Chou, Solheim, Marie H., Fujisaka, Shiho, Pan, Hui, Dreyfuss, Jonathan M., Bons, Joanna, Rose, Jacob, King, Christina D., Schilling, Birgit, Lusis, Aldons J., Pan, Calvin, Gupta, Manoj, Kulkarni, Rohit N., Fitzgerald, Kevin, Kern, Philip A., Divanovic, Senad, Kahn, C. Ronald, Softic, Samir

Source: In Metabolism August 2023 145

Proteomic Analysis of Huntington’s Disease Medium Spiny Neurons Identifies Alterations in Lipid Droplets

Authors: Tshilenge, Kizito-Tshitoko, Aguirre, Carlos Galicia, Bons, Joanna, Gerencser, Akos A., Basisty, Nathan, Song, Sicheng, Rose, Jacob, Lopez-Ramirez, Alejandro, Naphade, Swati, Loureiro, Ashley, Battistoni, Elena, Milani, Mateus, Wehrfritz, Cameron, Holtz, Anja, Hetz, Claudio, Mooney, Sean D., Schilling, Birgit, Ellerby, Lisa M.

Source: In Molecular & Cellular Proteomics May 2023 22(5)

Histone malonylation is regulated by SIRT5 and KAT2A

Authors: Zhang, Ran ¹, Bons, Joanna ¹, Scheidemantle, Grace ², Liu, Xiaojing ², Bielska, Olga ¹, Carrico, Chris ¹, Rose, Jacob ¹, Heckenbach, Indra ^{1, 3}, Scheibye-Knudsen, Morten ³, Schilling, Birgit ¹, Verdin, Eric ^{1, 4, ∗}

Source: In iScience 17 March 2023 26(3)

A proteomic view of cellular responses of macrophages to copper when added as ion or as copper-polyacrylate complex

Authors: Dalzon, Bastien, Devcic, Julie, Bons, Joanna, Torres, Anaelle, Diemer, Hélène, Ravanel, Stéphane, Collin-Faure, Véronique, Cianférani, Sarah, Carapito, Christine, Rabilloud, Thierry

Source: In Journal of Proteomics 15 May 2021 239

Optimized Sample Preparation and Data Processing of Data-Independent Acquisition Methods for the Robust Quantification of Trace-Level Host Cell Protein Impurities in Antibody Drug Products

Authors: Pythoud, Nicolas, Bons, Joanna, Mijola, Geoffroy, Beck, Alain, Cianférani, Sarah, Carapito, Christine

Source: Journal of proteome research. 20(1):923-931

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN625694200&indx=1&recIds=ETOCRN625694200

Sirtuin-5 Is Recruited to Hepatic Peroxisomes in Mice Fed Dodecanedioic Acid but Has Little Impact on the Peroxisomal Succinylome.

Authors: Zhang, Yuxun, Zhang, Bob B., Bharathi, Sivakama S., Bons, Joanna, Rose, Jacob P., Shah, Samah, Dobrowolski, Steven F., Sims-Lucas, Sunder, Schilling, Birgit, Goetzman, Eric S.

Source: Biomolecules (2218-273X); Dec2024, Vol. 14 Issue 12, p1508, 15p

Subject Terms: FATTY acid oxidation, DICARBOXYLIC acids, PEROXISOMES, MASS spectrometry, ACYL coenzyme A

Data‐independent acquisition and quantification of extracellular matrix from human lung in chronic inflammation‐associated carcinomas

Authors: Bons, Joanna, Pan, Deng, Shah, Samah, Bai, Rosemary, Chen‐Tanyolac, Chira, Wang, Xianhong, Elliott, Daffolyn R. Fels, Urisman, Anatoly, O'Broin, Amy, Basisty, Nathan, Rose, Jacob, Sangwan, Veena, Camilleri‐Broët, Sophie, Tankel, James, Gascard, Philippe, Ferri, Lorenzo, Tlsty, Thea D., Schilling, Birgit

Source: Proteomics. 23(7-8)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183680246.0x000001&indx=1&recIds=ETOCvdc_100183680246.0x000001

In‐depth analysis of the Sirtuin 5‐regulated mouse brain malonylome and succinylome using library‐free data‐independent acquisitions

Authors: Bons, Joanna, Rose, Jacob, Zhang, Ran, Burton, Jordan B, Carrico, Christopher, Verdin, Eric, Schilling, Birgit

Source: Proteomics. 23(3-4)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100175272733.0x000001&indx=1&recIds=ETOCvdc_100175272733.0x000001

A Combined N-terminomics and Shotgun Proteomics Approach to Investigate the Responses of Human Cells to Rapamycin and Zinc at the Mitochondrial Level

Authors: Bons, Joanna ^{‡, ‖}, Macron, Charlotte ^{‡, ‖, **}, Aude-Garcia, Catherine ^{§, ¶¶}, Vaca-Jacome, Sebastian Alvaro ^{‡, ‡‡}, Rompais, Magali ^‡, Cianférani, Sarah ^‡, Carapito, Christine ^{‡, §§, ‖}, Rabilloud, Thierry ^{§, ¶, ‖}

Source: In Molecular & Cellular Proteomics June 2019 18(6):1085-1095

The longer the worse: a combined proteomic and targeted study of the long-term versus short-term effects of silver nanoparticles on macrophagesElectronic supplementary information (ESI) available. See DOI: 10.1039/c9en01329f

Authors: Dalzon, Bastien, Aude-GarciaDeceased Nov. 21st, 2018. This paper is dedicated to her memory., Catherine, Diemer, Hélène, Bons, Joanna, Marie-Desvergne, Caroline, Pérard, Julien, Dubosson, Muriel, Collin-Faure, Véronique, Carapito, Christine, Cianférani, Sarah, Carrière, Marie, Rabilloud, Thierry

Source: Environmental science.Nano. 7(7):2032-2046

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108599872.0x000001&indx=1&recIds=ETOCvdc_100108599872.0x000001

Sirt2 Regulates Liver Metabolism in a Sex-Specific Manner.

Authors: Schmidt, Alexandra V., Bharathi, Sivakama S., Solo, Keaton J., Bons, Joanna, Rose, Jacob P., Schilling, Birgit, Goetzman, Eric S.

Source: Biomolecules (2218-273X); Sep2024, Vol. 14 Issue 9, p1160, 17p

Subject Terms: LIVER mitochondria, SIRTUINS, PROTEIN metabolism, GLUCOSE metabolism, FAT

Succinylation of Park7 activates a protective metabolic response to acute kidney injury.

Authors: Pfister, Katherine, Young, Victoria, Frankel, Brendon, Silva Barbosa, Anne, Burton, Jordan, Bons, Joanna, Bob Zhang, Takuto Chiba, Uhlean, Rebecca, Goetzma, Eric, Schilling, Birgit, Sims-Lucas, Sunder

Source: American Journal of Physiology: Renal Physiology; Jul2024, Vol. 327 Issue 1, pF128-F136, 9p

Subject Terms: ACUTE kidney failure, CHRONIC kidney failure, POST-translational modification, PARKINSON'S disease, PHYSIOLOGY

Studying the Fate of Tumor Extracellular Vesicles at High Spatiotemporal Resolution Using the Zebrafish Embryo

Authors: Hyenne, Vincent, Ghoroghi, Shima, Collot, Mayeul, Bons, Joanna, Follain, Gautier, Harlepp, Sébastien, Mary, Benjamin, Bauer, Jack, Mercier, Luc, Busnelli, Ignacio, Lefebvre, Olivier, Fekonja, Nina, Garcia-Leon, Maria J., Machado, Pedro, Delalande, François, López, Ana Amor, Silva, Susana Garcia, Verweij, Frederik J., van Niel, Guillaume, Djouad, Farida, Peinado, Héctor, Carapito, Christine, Klymchenko, Andrey S., Goetz, Jacky G.

Source: In Developmental Cell 25 February 2019 48(4):554-572

Role of the Senescence-Associated Factor Dipeptidyl Peptidase 4 in the Pathogenesis of SARS-CoV-2 Infection.

Authors: Deinhardt-Emmer, Stefanie, Deshpande, Sharvari, Kitazawa, Koji, Herman, Allison B., Bons, Joanna, Rose, Jacob P., Kumar, Prasanna Ashok, Anerillas, Carlos, Neri, Francesco, Ciotlos, Serban, Perez, Kevin, Köse-Vogel, Nilay, Häder, Antje, Abdelmohsen, Kotb, Löffler, Bettina, Gorospe, Myriam, Desprez, Pierre-Yves, Melov, Simon, Furman, David, Schilling, Birgit

Source: Aging & Disease; Jun2024, Vol. 15 Issue 3, p1398-1415, 18p

Subject Terms: SARS-CoV-2, PEPTIDASE, PROTEIN expression

Therapeutic targeting of HYPDH/PRODH2 with N-propargylglycine offers a Hyperoxaluria treatment opportunity

Authors: Bons, Joanna ^{a, 1}, Tadeo, Ada ^{a, 1}, Scott, Gary K. ^{a, 1}, Teramayi, Fadzai ^a, Tanner, John J. ^b, Schilling, Birgit ^a, Benz, Christopher C. ^{a, ⁎, 2}, Ellerby, Lisa M. ^{a, ⁎, 2}

Source: In BBA - Molecular Basis of Disease January 2024 1870(1)