The mitophagy receptor BNIP3 is critical for the regulation of metabolic homeostasis and mitochondrial function in the nucleus pulposus cells of the intervertebral disc

Authors: Madhu, Vedavathi, Hernandez-Meadows, Miriam, Boneski, Paige K, Qiu, Yunping, Guntur, Anyonya R, Kurland, Irwin J., Barve, Ruteja A, Risbud, Makarand V.

Source: Autophagy. 19(6):1821-1843

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185048260.0x000001&indx=1&recIds=ETOCvdc_100185048260.0x000001

Substitution of PINK1 Gly411 modulates substrate receptivity and turnover

Authors: Fiesel, Fabienne C, Fričová, Dominika, Hayes, Caleb S, Coban, Mathew A, Hudec, Roman, Bredenberg, Jenny M, Broadway, Benjamin J, Markham, Briana N, Yan, Tingxiang, Boneski, Paige K, Fiorino, Gabriella, Watzlawik, Jens O, Hou, Xu, McCarty, Arthur M, Lewis-Tuffin, Laura J, Zhong, Jun, Madden, Benjamin J, Ordureau, Alban, An, Heeseon, Puschmann, Andreas, Wszolek, Zbigniew K, Ross, Owen A, Harper, J Wade, Caulfield, Thomas R, Springer, Wolfdieter

Source: Autophagy. 19(6):1711-1732

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185048118.0x000001&indx=1&recIds=ETOCvdc_100185048118.0x000001

Hypoxic Regulation of Mitochondrial Metabolism and Mitophagy in Nucleus Pulposus Cells Is Dependent on HIF‐1α–BNIP3 Axis

Authors: Madhu, Vedavathi, Boneski, Paige K, Silagi, Elizabeth, Qiu, Yunping, Kurland, Irwin, Guntur, Anyonya R, Shapiro, Irving M, Risbud, Makarand V

Source: Journal of bone and mineral research. 35(8):1504-1524

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108117604.0x000001&indx=1&recIds=ETOCvdc_100108117604.0x000001

Structural and Functional Characterization of the Most Frequent Pathogenic PRKN Substitution p.R275W.

Authors: Bustillos, Bernardo A., Cocker, Liam T., Coban, Mathew A., Weber, Caleb A., Bredenberg, Jenny M., Boneski, Paige K., Siuda, Joanna, Slawek, Jaroslaw, Puschmann, Andreas, Narendra, Derek P., Graff-Radford, Neill R., Wszolek, Zbigniew K., Dickson, Dennis W., Ross, Owen A., Caulfield, Thomas R., Springer, Wolfdieter, Fiesel, Fabienne C.

Source: Cells (2073-4409); Sep2024, Vol. 13 Issue 18, p1540, 20p

Subject Terms: PARKINSON'S disease, UBIQUITIN, FIBROBLASTS, FUNCTIONAL analysis, FLOW cytometry

Systematic Functional Analysis of PINK1 and PRKN Coding Variants.

Authors: Broadway, Benjamin J.¹ (AUTHOR), Boneski, Paige K.¹ (AUTHOR), Bredenberg, Jenny M.¹ (AUTHOR), Kolicheski, Ana¹ (AUTHOR), Hou, Xu¹ (AUTHOR), Soto-Beasley, Alexandra I.¹ (AUTHOR), Ross, Owen A.^1,2,3 (AUTHOR), Springer, Wolfdieter^1,2 (AUTHOR), Fiesel, Fabienne C.^1,2 (AUTHOR) fiesel.fabienne@mayo.edu

Source: Cells (2073-4409). Aug2022, Vol. 11 Issue 15, p2426-2426. 19p.

Subject Terms: *FUNCTIONAL analysis, *LYSOSOMES, *PARKINSON'S disease, *GENOME editing, *UBIQUITIN, *GENETIC mutation