Ellagic acid and its metabolites urolithins A/B ameliorate most common disease phenotypes in cellular and mouse models for lysosomal storage disorders by enhancing extracellular vesicle secretion

Authors: Beatriz Soto-Huelin, Bohdan Babiy, Oscar Pastor, Mario Díaz-García, Ana Toledano-Zaragoza, María Dolores Frutos, Juan Carlos Espín, Francisco A. Tomás-Barberán, Rebeca Busto, María Dolores Ledesma

Source: Neurobiology of Disease, Vol 182, Iss , Pp 106141- (2023)

Subject Terms: Extracellular vesicles, Polyphenols, Lysosomal storage disorders, Niemann pick, Brain, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996123001559; https://doaj.org/toc/1095-953X

Access URL: https://doaj.org/article/41ec54e488d340289457ccc81c47e41e

Rottlerin Stimulates Exosome/Microvesicle Release Via the Increase of Ceramide Levels Mediated by Ampk in an In Vitro Model of Intracellular Lipid Accumulation

Authors: Yessenia L. Molina, David García-Seisdedos, Bohdan Babiy, Milagros Lerma, Javier Martínez-Botas, María J. Casarejos, María T. Vallejo, Diego Gómez-Coronado, Miguel A. Lasunción, Óscar Pastor, Rebeca Busto

Source: Biomedicines, Vol 10, Iss 6, p 1316 (2022)

Subject Terms: rottlerin, exosome/microvesicle, intracellular lipid trafficking, ceramide, sphingolipid, lysosomal storage disease, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/10/6/1316; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/c4a8ae005cca432399f9442792dac2a4