Hepatitis D virus infection triggers CXCL9-11 upregulation in hepatocytes and liver infiltration of CXCR3+ CD4 T cells

Authors: Bockmann, Jan-Hendrik ^{1, 2, ⁎}, Allweiss, Lena ^{1, 2}, Volmari, Annika ^{1, 2}, da Fonseca Araújo, David ¹, Kohsar, Matin ^{1, 3}, Hyrina, Anastasia ⁴, Kah, Janine ^{1, 5}, Song, Zhijuan ⁴, Chan, Josolyn ⁴, Giersch, Katja ^{1, 6}, Volz, Tassilo ^{1, 2}, Lütgehetmann, Marc ^{2, 6}, Wallin, Jeffrey J. ⁴, Manuilov, Dmitry ⁴, Holdorf, Meghan M. ⁴, Fletcher, Simon P. ⁴, Lohse, Ansgar W. ^{1, 2}, Bertoletti, Antonio ⁷, Schulze zur Wiesch, Julian ^{1, 2}, Dandri, Maura ^{1, 2}

Source: In JHEP Reports March 2025 7(3)

Blocking viral entry with bulevirtide reduces the number of HDV-infected hepatocytes in human liver biopsies

Authors: Allweiss, Lena, Volmari, Annika, Suri, Vithika, Wallin, Jeffrey J., Flaherty, John F., Manuilov, Dmitry, Downie, Bryan, Lütgehetmann, Marc, Bockmann, Jan-Hendrik, Urban, Stephan, Wedemeyer, Heiner, Dandri, Maura

Source: In Journal of Hepatology June 2024 80(6):882-891

T-cell engager antibodies enable T cells to control HBV infection and to target HBsAg-positive hepatoma in mice

Authors: Quitt, Oliver, Luo, Shanshan, Meyer, Marten, Xie, Zhe, Golsaz-Shirazi, Forough, Loffredo-Verde, Eva, Festag, Julia, Bockmann, Jan Hendrik, Zhao, Lili, Stadler, Daniela, Chou, Wen-Min, Tedjokusumo, Raindy, Wettengel, Jochen Martin, Ko, Chunkyu, Noeßner, Elfriede, Bulbuc, Nadja, Shokri, Fazel, Lüttgau, Sandra, Heikenwälder, Mathias, Bohne, Felix, Moldenhauer, Gerhard, Momburg, Frank, Protzer, Ulrike

Source: In Journal of Hepatology November 2021 75(5):1058-1071

Comparative Analysis of the Antiviral Effects Mediated by Type I and III Interferons in Hepatitis B Virus–Infected Hepatocytes

Authors: Bockmann, Jan-Hendrik, Stadler, Daniela, Xia, Yuchen, Ko, Chunkyu, Wettengel, Jochen M., zur Wiesch, Julian Schulze, Dandri, Maura, Protzer, Ulrike

Source: The Journal of Infectious Diseases, 2019 Aug . 220(4), 567-577.

Access URL: https://www.jstor.org/stable/26758743

Detection of a Broad Range of Low-Level Major Histocompatibility Complex Class II–Restricted, Hepatitis Delta Virus (HDV)–Specific T-Cell Responses Regardless of Clinical Status

Authors: Landahl, Johanna, Bockmann, Jan Hendrik, Scheurich, Christoph, Ackermann, Christin, Matzat, Verena, Heide, Janna, Nuurei, Tungalag, D’Antonio, Gianluca, von Felden, Johann, Sette, Alessandro, Peine, Sven, Lohse, Ansgar W., Luetgehetmann, Marc, Marget, Matthias, Sidney, John, zur Wiesch, Julian Schulze

Source: The Journal of Infectious Diseases, 2019 Feb . 219(4), 568-577.

Access URL: https://www.jstor.org/stable/26748962

Hepatitis B Virus Activates Signal Transducer and Activator of Transcription 3 Supporting Hepatocyte Survival and Virus Replication

Authors: Hösel, Marianna, Quasdorff, Maria, Ringelhan, Marc, Kashkar, Hamid, Debey-Pascher, Svenja, Sprinzl, Martin F., Bockmann, Jan-Hendrik, Arzberger, Silke, Webb, Dennis, von Olshausen, Gesa, Weber, Achim, Schultze, Joachim L., Büning, Hildegard, Heikenwalder, Mathias, Protzer, Ulrike

Source: In Cellular and Molecular Gastroenterology and Hepatology November 2017 4(3):339-363

T Cells Engineered to Express a T-Cell Receptor Specific for Glypican-3 to Recognize and Kill Hepatoma Cells In Vitro and in Mice

Authors: Dargel, Christina, Bassani-Sternberg, Michal, Hasreiter, Julia, Zani, Fabio, Bockmann, Jan-Hendrik, Thiele, Frank, Bohne, Felix, Wisskirchen, Karin, Wilde, Susanne, Sprinzl, Martin F., Schendel, Dolores J., Krackhardt, Angela M., Uckert, Wolfgang, Wohlleber, Dirk, Schiemann, Matthias, Stemmer, Kerstin, Heikenwälder, Mathias, Busch, Dirk H., Richter, Günther, Mann, Matthias, Protzer, Ulrike

Source: In Gastroenterology October 2015 149(4):1042-1052

High rates of cirrhosis and severe clinical events in patients with HBV/HDV co-infection: longitudinal analysis of a German cohort

Authors: Bockmann, Jan-Hendrik, Grube, Marcel, Hamed, Vanessa, von Felden, Johann, Landahl, Johanna, Wehmeyer, Malte, Giersch, Katja, Hall, Michaela T., Murray, John M., Dandri, Maura, Lüth, Stefan, Lohse, Ansgar W., Lütgehetmann, Marc, Schulze Zur Wiesch, Julian

Source: BMC gastroenterology. 20(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100161778464.0x000001&indx=1&recIds=ETOCvdc_100161778464.0x000001

Clinical establishment of a laboratory developed quantitative HDV PCR assay on the cobas6800 high-throughput system

Authors: Pflüger, Lisa Sophie, Nörz, Dominik, Volz, Tassilo, Giersch, Katja, Giese, Annika, Goldmann, Nora, Glebe, Dieter, Bockmann, Jan-Hendrik, Pfefferle, Susanne, Dandri, Maura, Schulze zur Wiesch, Julian, Lütgehetmann, Marc

Source: In JHEP Reports December 2021 3(6)

Hepatitis D coinfection is associated with enhanced CXCR3 receptor expression of CD4 memory T cells and intrahepatic CXCR3 ligand expression compared to chronic hepatitis B patients

Authors: Bockmann, Jan-Hendrik, Kohsar, Matin, Giersch, Katja, Allweiss, Lena, Kah, Janine, Volz, Tassilo, Ackermann, Christin, Pirosu, Andrea, Lutgehetmann, Marc, Lohse, Ansgar W., zur Wiesch, Julian Schulze, Dandri, Maura

Source: Journal of hepatology. 73(S1):S575-S575

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100120837636.0x000001&indx=1&recIds=ETOCvdc_100120837636.0x000001

FRI-134-Comparative analysis of intrahepatic and peripheral chemokine responses in chronic hepatitis B, C and D in vivo

Authors: Bockmann, Jan-Hendrik, Kohsar, Matin, Allweiss, Lena, Volz, Tassilo, Kah, Janine, Luetgehmann, Marc, Lohse, Ansgar W., zurWiesch, Julian Schulze, Dandri, Maura

Source: Journal of hepatology. 70(S):e446-e446

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100132072437.0x000001&indx=1&recIds=ETOCvdc_100132072437.0x000001

FRI359 - Hepatitis D coinfection is associated with enhanced CXCR3 receptor expression of CD4 memory T cells and intrahepatic CXCR3 ligand expression compared to chronic hepatitis B patients

Authors: Bockmann, Jan-Hendrik, Kohsar, Matin, Giersch, Katja, Allweiss, Lena, Kah, Janine, Volz, Tassilo, Ackermann, Christin, Pirosu, Andrea, Lutgehetmann, Marc, Lohse, Ansgar W., zur Wiesch, Julian Schulze, Dandri, Maura

Source: In Journal of Hepatology August 2020 73 Supplement 1:S575-S575

Comparison of the integrin α4β7 expression pattern of memory T cell subsets in HIV infection and ulcerative colitis.

Authors: Wittner, Melanie, Schlicker, Veronika, Libera, Jana, Bockmann, Jan-Hendrik, Horvatits, Thomas, Seiz, Oliver, Kummer, Silke, Manthey, Carolin F., Hüfner, Anja, Kantowski, Marcus, Rösch, Thomas, Degen, Olaf, Huber, Samuel, Eberhard, Johanna M., Schulze zur Wiesch, Julian

Source: PLoS ONE; 7/29/2019, Vol. 14 Issue 7, p1-23, 23p

Subject Terms: INTERLEUKIN-7, ULCERATIVE colitis, HIV infections, T cells, INFLAMMATORY bowel diseases, CYTOTOXIC T cells

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The challenge of protecting without overprotecting: The two sides of myeloid-derived suppressor cells in hepatitis B viral infection.

Authors: Dandri, Maura, Bockmann, Jan‐Hendrik

Source: Hepatology (02709139); Mar2016, Vol. 63 Issue 3, p1044-1046, 3p

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High Rates of Liver Cirrhosis and Hepatocellular Carcinoma in Chronic Hepatitis B Patients with Metabolic and Cardiovascular Comorbidities.

Authors: Bockmann, Jan-Hendrik, Kohsar, Matin, Murray, John M., Hamed, Vanessa, Dandri, Maura, Lüth, Stefan, Lohse, Ansgar W., Schulze-zur-Wiesch, Julian, Chemin, Isabelle

Source: Microorganisms; May2021, Vol. 9 Issue 5, p968, 1p

Subject Terms: CHRONIC hepatitis B, CIRRHOSIS of the liver, HEPATOCELLULAR carcinoma, CARDIOVASCULAR diseases, HEPATITIS B, CORONARY disease

Defining the CD39/CD73 Axis in SARS-CoV-2 Infection: The CD73- Phenotype Identifies Polyfunctional Cytotoxic Lymphocytes.

Authors: Ahmadi, Parimah, Hartjen, Philip, Kohsar, Matin, Kummer, Silke, Schmiedel, Stefan, Bockmann, Jan-Hendrik, Fathi, Anahita, Huber, Samuel, Haag, Friedrich, Schulze zur Wiesch, Julian

Source: Cells (2073-4409); Aug2020, Vol. 9 Issue 8, p1750, 1p

Subject Terms: CYTOTOXIC T cells, SARS-CoV-2, LYMPHOCYTES, TUMOR necrosis factors, COVID-19, T cells

˜Eineœ Analyse des angeborenen Immunsystems in Lebern chronisch Hepatitis B infizierter Patienten mit unterschiedlicher viraler Aktivität

Authors: Bockmann, Jan-Hendrik

Contributors: Petersen, Jörg

Availability: http://data.europeana.eu/aggregation/europeana/2048441/item_BGD3MN7AG6FSEFG22YV2HV72IYTXJ6KD