DNA Sequence Variations Affecting Serotonin Transporter Transcriptional Regulation and Activity: Do They Impact Alcohol Addiction?

Authors: Ferraguti, Giampiero, Francati, Silvia, Codazzo, Claudia, Blaconà, Giovanna, Testino, Giancarlo, Angeloni, Antonio, Fiore, Marco, Ceccanti, Mauro, Lucarelli, Marco

Source: International Journal of Molecular Sciences; Aug2024, Vol. 25 Issue 15, p8089, 17p

Subject Terms: MOLECULAR biology, GENE expression, GENETIC variation, SEROTONIN uptake inhibitors, ALCOHOLISM, SEROTONIN, INTRONS

L1077P CFTR pathogenic variant function rescue by Elexacaftor–Tezacaftor–Ivacaftor in cystic fibrosis patient-derived air–liquid interface (ALI) cultures and organoids: in vitro guided personalized therapy of non-F508del patients.

Authors: Lo Cicero, Stefania, Castelli, Germana, Blaconà, Giovanna, Bruno, Sabina Maria, Sette, Giovanni, Pigliucci, Riccardo, Villella, Valeria Rachela, Esposito, Speranza, Zollo, Immacolata, Spadaro, Francesca, Maria, Ruggero De, Biffoni, Mauro, Cimino, Giuseppe, Amato, Felice, Lucarelli, Marco, Eramo, Adriana

Source: Respiratory Research; 9/6/2023, Vol. 24, p1-19, 19p

Quantitative Evaluation of CFTR Gene Expression: A Comparison between Relative Quantification by Real-Time PCR and Absolute Quantification by Droplet Digital PCR.

Authors: Bruno, Sabina Maria¹ (AUTHOR) sabinamaria.bruno@gmail.com, Blaconà, Giovanna¹ (AUTHOR) giovannablak@gmail.com, Lo Cicero, Stefania² (AUTHOR) stefania.locicero@iss.it, Castelli, Germana² (AUTHOR) germana.castelli@iss.it, Virgulti, Mariarita¹ (AUTHOR) virgulti.1949280@studenti.uniroma1.it, Testino, Giancarlo¹ (AUTHOR) gi.testino@tiscali.it, Pierandrei, Silvia¹ (AUTHOR) pierandrei.silvia@gmail.com, Fuso, Andrea¹ (AUTHOR) andrea.fuso@uniroma1.it, Cimino, Giuseppe³ (AUTHOR) ciminolo@tiscali.it, Ferraguti, Giampiero¹ (AUTHOR) giampiero.ferraguti@uniroma1.it, Eramo, Adriana² (AUTHOR) adriana.eramo@iss.it, Lucarelli, Marco¹ (AUTHOR) marco.lucarelli@uniroma1.it

Source: Genes. Sep2023, Vol. 14 Issue 9, p1781. 12p.

Subject Terms: *CYSTIC fibrosis transmembrane conductance regulator, *CHLORIDE channels, *GENE expression

Two novel and correlated CF-causing insertions in the (TG)mTn tract of the CFTR gene.

Authors: Pierandrei, Silvia¹, Blaconà, Giovanna², Fabrizzi, Benedetta³, Cimino, Giuseppe⁴, Cirilli, Natalia³, Caporelli, Nicole³, Angeloni, Antonio², Cipolli, Marco³, Lucarelli, Marco^2,5 marco.lucarelli@uniroma1.it

Source: PLoS ONE. 10/7/2019, Vol. 14 Issue 10, p1-14. 14p.

Subject Terms: *CYSTIC fibrosis transmembrane conductance regulator, *BURKHOLDERIA infections, *NON-coding RNA, *RNA splicing, *MEDICAL genetics

Urine Dipstick Analysis on Automated Platforms: Is a Reliable Screening Tool for Proteinuria? An Experience from Umberto I Hospital in Rome.

Authors: Terracina, Sergio, Pallaria, Antonio, Lucarelli, Marco, Angeloni, Antonio, De Angelis, Annarita, Ceci, Flavio Maria, Caronti, Brunella, Francati, Silvia, Blaconà, Giovanna, Fiore, Marco, Ferraguti, Giampiero

Source: Biomedicines; Apr2023, Vol. 11 Issue 4, p1174, 13p

Subject Terms: URINALYSIS, MEDICAL screening, PROTEINURIA, DIABETIC nephropathies, CHRONIC kidney failure, KIDNEY failure, KIDNEY diseases

Geographic Terms: ROME

The RNA-Binding Protein SMN as a Novel Player in Laryngeal Squamous Cell Carcinoma.

Authors: Gabanella, Francesca, Colizza, Andrea, Mottola, Maria Chiara, Francati, Silvia, Blaconà, Giovanna, Petrella, Carla, Barbato, Christian, Greco, Antonio, Ralli, Massimo, Fiore, Marco, Corbi, Nicoletta, Ferraguti, Giampiero, Corsi, Alessandro, Minni, Antonio, de Vincentiis, Marco, Passananti, Claudio, Di Certo, Maria Grazia

Source: International Journal of Molecular Sciences; Jan2023, Vol. 24 Issue 2, p1794, 19p

Subject Terms: RNA-binding proteins, SQUAMOUS cell carcinoma, RNA metabolism, EPIDERMAL growth factor receptors, HEAD & neck cancer, MESSENGER RNA

Sperm DNA Fragmentation and Sperm-Borne miRNAs: Molecular Biomarkers of Embryo Development?

Authors: Conflitti, Anna Chiara, Cicolani, Gaia, Buonacquisto, Alessandra, Pallotti, Francesco, Faja, Fabiana, Bianchini, Serena, Blaconà, Giovanna, Bruno, Sabina Maria, Linari, Antonella, Lucarelli, Marco, Montanino, Diletta, Muzii, Ludovico, Lenzi, Andrea, Lombardo, Francesco, Paoli, Donatella

Source: International Journal of Molecular Sciences; Jan2023, Vol. 24 Issue 2, p1007, 18p

Subject Terms: EMBRYOS, MICRORNA, SEMEN analysis, DNA, REPRODUCTIVE technology, HUMAN embryology, SPERMATOZOA

NGF and the Male Reproductive System: Potential Clinical Applications in Infertility.

Authors: Ferraguti, Giampiero, Fanfarillo, Francesca, Tarani, Luigi, Blaconà, Giovanna, Tarani, Francesca, Barbato, Christian, Minni, Antonio, Ralli, Massimo, Francati, Silvia, Greco, Antonio, Petrella, Carla, Fiore, Marco

Source: International Journal of Molecular Sciences; Nov2022, Vol. 23 Issue 21, p13127, 22p

Subject Terms: MALE reproductive organs, HYPOTHALAMUS, NERVE growth factor, CLINICAL medicine, INFERTILITY, REPRODUCTIVE technology, SPERMATOGENESIS

Company/Entity: WORLD Health Organization

Downregulation of epithelial sodium channel (ENaC) activity in cystic fibrosis cells by epigenetic targeting.

Authors: Blaconà, Giovanna¹ (AUTHOR), Raso, Roberto¹ (AUTHOR), Castellani, Stefano² (AUTHOR), Pierandrei, Silvia¹ (AUTHOR), Del Porto, Paola³ (AUTHOR), Ferraguti, Giampiero¹ (AUTHOR), Ascenzioni, Fiorentina³ (AUTHOR), Conese, Massimo⁴ (AUTHOR) massimo.conese@unifg.it, Lucarelli, Marco^1,5 (AUTHOR) marco.lucarelli@uniroma1.it

Source: Cellular & Molecular Life Sciences. May2022, Vol. 79 Issue 5, p1-11. 11p.

Correction to: L1077P CFTR pathogenic variant function rescue by Elexacaftor–Tezacaftor–Ivacaftor in cystic fbrosis patient-derived air–liquid interface (ALI) cultures and organoids: in vitro guided personalized therapy of non-F508del patients

Authors: Lo Cicero, Stefania, Castelli, Germana, Blaconà, Giovanna, Bruno, Sabina Maria, Sette, Giovanni, Pigliucci, Riccardo, Villella, Valeria Rachela, Esposito, Speranza, Zollo, Immacolata, Spadaro, Francesca, De Maria, Ruggero, Biffoni, Mauro, Cimino, Giuseppe, Amato, Felice, Lucarelli, Marco, Eramo, Adriana

Source: Respiratory Research; 9/23/2023, Vol. 24 Issue 1, p1-2, 2p

Subject Terms: CYSTIC fibrosis transmembrane conductance regulator, ORGANOIDS