Structure guided mutagenesis reveals the substrate determinants of guanine deaminase

Authors: Singh, Jayanti, Gaded, Vandana, Bitra, Aruna, Anand, Ruchi

Source: In Journal of Structural Biology September 2021 213(3)

A molecular switch in mouse CD1d modulates natural killer T cell activation by α-galactosylsphingamides

Alternate Title: Sphingamide recognition by NKT cells (English)

Authors: Wang, Jing, Guillaume, Joren, Janssens, Jonas, Remesh, Soumya G., Ying, Ge, Bitra, Aruna, Van Calenbergh, Serge, Zajonc, Dirk M.

Source: In Journal of Biological Chemistry 27 September 2019 294(39):14345-14356

Structure of human cytomegalovirus UL144, an HVEM orthologue, bound to the B and T cell lymphocyte attenuator

Alternate Title: Crystal structure of the UL144–BTLA complex (English)

Authors: Bitra, Aruna, Nemčovičová, Ivana, Picarda, Gaelle, Doukov, Tzanko, Wang, Jing, Benedict, Chris A., Zajonc, Dirk M.

Source: In Journal of Biological Chemistry 5 July 2019 294(27):10519-10529

Crystal structure of the m4-1BB/4-1BBL complex reveals an unusual dimeric ligand that undergoes structural changes upon 4-1BB receptor binding

Authors: Bitra, Aruna, Doukov, Tzanko, Destito, Giuseppe, Croft, Michael, Zajonc, Dirk M. ^**

Source: In Journal of Biological Chemistry February 2019 294(6):1831-1845

Crystal structures of the human 4-1BB receptor bound to its ligand 4-1BBL reveal covalent receptor dimerization as a potential signaling amplifier

Authors: Bitra, Aruna, Doukov, Tzanko, Croft, Michael, Zajonc, Dirk M.

Source: In Journal of Biological Chemistry 29 June 2018 293(26):9958-9969

Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling

Authors: Bitra, Aruna, Doukov, Tzanko, Wang, Jing, Picarda, Gaelle, Benedict, Chris A., Croft, Michael, Zajonc, Dirk M. ^**

Source: In Journal of Biological Chemistry 26 January 2018 293(4):1317-1329

Structure–function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D8

Alternate Title: Human antibody responses to vaccinia virus D8 (English)

Authors: Matho, Michael H., Schlossman, Andrew, Gilchuk, Iuliia M., Miller, Greg, Mikulski, Zbigniew, Hupfer, Matthias, Wang, Jing, Bitra, Aruna, Meng, Xiangzhi ^**, Xiang, Yan ^**, Kaever, Tom, Doukov, Tzanko, Ley, Klaus, Crotty, Shane, Peters, Bjoern, Hsieh-Wilson, Linda C., Crowe, James E., Jr., Zajonc, Dirk M.

Source: In Journal of Biological Chemistry 5 January 2018 293(1):390-401

4'‐O‐Alkylated α‐Galactosylceramide Analogues as iNKT‐Cell Antigens: Synthetic, Biological, and Structural Studies

Authors: Janssens, Jonas, Bitra, Aruna, Wang, Jing, Decruy, Tine, Venken, Koen, van der Eycken, Johan, Elewaut, Dirk, Zajonc, Dirk M., van Calenbergh, Serge

Source: ChemMedChem. 14(1):147-168

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100123094551.0x000001&indx=1&recIds=ETOCvdc_100123094551.0x000001

An in silico—in vitro Pipeline Identifying an HLA-A^*02:01⁺ KRAS G12V⁺ Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients.

Authors: Mishto, Michele, Mansurkhodzhaev, Artem, Ying, Ge, Bitra, Aruna, Cordfunke, Robert A., Henze, Sarah, Paul, Debdas, Sidney, John, Urlaub, Henning, Neefjes, Jacques, Sette, Alessandro, Zajonc, Dirk M., Liepe, Juliane

Source: Frontiers in Immunology; 11/15/2019, Vol. 10, p1-17, 17p

Subject Terms: TUMOR antigens, CANCER patients, PIPELINES, T cells, CELLULAR therapy

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