Human iPSC and CRISPR targeted gene knock-in strategy for studying the somatic TIE2^L914F mutation in endothelial cells.

Authors: Lazovic, Bojana, Nguyen, Hoang-Tuan, Ansarizadeh, Mohammadhassan, Wigge, Leif, Kohl, Franziska, Li, Songyuan, Carracedo, Miguel, Kettunen, Jere, Krimpenfort, Luc, Elgendy, Ramy, Richter, Kati, De Silva, Laknee, Bilican, Bilada, Singh, Prateek, Saxena, Pratik, Jakobsson, Lars, Hong, Xuechong, Eklund, Lauri, Hicks, Ryan

Source: Angiogenesis; Aug2024, Vol. 27 Issue 3, p523-542, 20p

Subject Terms: INDUCED pluripotent stem cells, GENE expression, ENDOTHELIAL cells, GENOME editing, SHEARING force

CellSIUS provides sensitive and specific detection of rare cell populations from complex single-cell RNA-seq data

Authors: Wegmann, Rebekka, Neri, Marilisa, Schuierer, Sven, Bilican, Bilada, Hartkopf, Huyen, Nigsch, Florian, Mapa, Felipa, Waldt, Annick, Cuttat, Rachel, Salick, Max, Raymond, Joe, Kaykas, Ajamete, Roma, Guglielmo, Keller, Caroline

Source: Genome biology. 20(1):1-21

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100189302971.0x000001&indx=1&recIds=ETOCvdc_100189302971.0x000001

High Yields of Oligodendrocyte Lineage Cells from Human Embryonic Stem Cells at Physiological Oxygen Tensions for Evaluation of Translational Biology

Authors: Stacpoole, Sybil R.L., Spitzer, Sonia, Bilican, Bilada, Compston, Alastair, Karadottir, Ragnhildur, Chandran, Siddharthan, Franklin, Robin J.M.

Source: In Stem Cell Reports 19 November 2013 1(5):437-450

Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy

Authors: Serio, Andrea, Bilican, Bilada, Barmada, Sami J., Ando, Dale Michael, Zhao, Chen, Siller, Rick, Burr, Karen, Haghi, Ghazal, Story, David, Nishimura, Agnes Lumi, Carrasco, Monica A., Phatnani, Hemali P., Shum, Carole, Wilmut, Ian, Maniatis, Tom, Shaw, Christopher E., Finkbeiner, Steven, Chandran, Siddharthan

Source: Proceedings of the National Academy of Sciences of the United States of America, 2013 Mar . 110(12), 4697-4702.

Access URL: https://www.jstor.org/stable/42583331

Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability

Authors: Bilican, Bilada, Serio, Andrea, Barmada, Sami J., Nishimura, Agnes Lumi, Sullivan, Gareth J., Carrasco, Monica, Phatnani, Hemali P., Puddifoot, Clare A., Story, David, Fletcher, Judy, Park, In-Hyun, Friedman, Brad A., Daley, George Q., Wyllie, David J. A., Hardingham, Giles E., Wilmut, Ian, Finkbeiner, Steven, Maniatis, Tom, Shaw, Christopher E., Chandran, Siddharthan

Source: Proceedings of the National Academy of Sciences of the United States of America, 2012 Apr 01. 109(15), 5803-5808.

Access URL: https://www.jstor.org/stable/41588246

A proteogenomic view of Parkinson's disease causality and heterogeneity.

Authors: Kaiser, Sergio, Zhang, Luqing, Mollenhauer, Brit, Jacob, Jaison, Longerich, Simonne, Del-Aguila, Jorge, Marcus, Jacob, Raghavan, Neha, Stone, David, Fagboyegun, Olumide, Galasko, Douglas, Dakna, Mohammed, Bilican, Bilada, Dovlatyan, Mary, Kostikova, Anna, Li, Jingyao, Peterson, Brant, Rotte, Michael, Sanz, Vinicius, Foroud, Tatiana

Source: NPJ Parkinson's Disease; 2/11/2023, Vol. 9 Issue 1, p1-13, 13p

Correction: Human iPSC and CRISPR targeted gene knock-in strategy for studying the somatic TIE2L914F mutation in endothelial cells.

Authors: Lazovic, Bojana, Nguyen, Hoang-Tuan, Ansarizadeh, Mohammadhassan, Wigge, Leif, Kohl, Franziska, Li, Songyuan, Carracedo, Miguel, Kettunen, Jere, Krimpenfort, Luc, Elgendy, Ramy, Richter, Kati, De Silva, Laknee, Bilican, Bilada, Singh, Prateek, Saxena, Pratik, Jakobsson, Lars, Hong, Xuechong, Eklund, Lauri, Hicks, Ryan

Source: Angiogenesis; Aug2024, Vol. 27 Issue 3, p543-544, 2p

Subject Terms: MEDICAL physics, CLINICAL biochemistry, MICROSCOPY, IMAGE analysis, ENDOTHELIAL cells

Cell cycle regulation of the T-box transcription factor tbx2

Authors: Bilican, Bilada, Goding, Colin R.

Source: In Experimental Cell Research 2006 312(12):2358-2366

Physiological Normoxia and Absence of EGF Is Required for the Long-Term Propagation of Anterior Neural Precursors from Human Pluripotent Cells.

Authors: Bilican, Bilada^1,2,3, Livesey, Matthew R.^1,3,4, Haghi, Ghazal^1,3,4, Qiu, Jing⁴, Burr, Karen^1,2,3, Siller, Rick^2,3, Hardingham, Giles E.⁴, Wyllie, David J. A.⁴ dwyllie1@staffmail.ed.ac.uk, Chandran, Siddharthan^1,2,3 siddharthan.chandran@ed.ac.uk

Source: PLoS ONE. Jan2014, Vol. 9 Issue 1, p1-11. 11p.

Subject Terms: *EPIDERMAL growth factor, *PLURIPOTENT stem cells, *BRAIN physiology, *BRAIN function localization, *CELL differentiation, *DEVELOPMENTAL neurobiology

Genetic Ablation of AXL Does Not Protect Human Neural Progenitor Cells and Cerebral Organoids from Zika Virus Infection

Authors: Wells, Michael F., Salick, Max R., Wiskow, Ole, Ho, Daniel J., Worringer, Kathleen A., Ihry, Robert J., Kommineni, Sravya, Bilican, Bilada, Klim, Joseph R., Hill, Ellen J., Kane, Liam T., Ye, Chaoyang, Kaykas, Ajamete, Eggan, Kevin

Source: In Cell Stem Cell 1 December 2016 19(6):703-708

Induction of Olig2⁺ Precursors by FGF Involves BMP Signalling Blockade at the Smad Level.

Authors: Bilican, Bilada¹ bb337@cam.ac.uk, Fiore-Heriche, Christelle², Compston, Alastair¹, Allen, Nicholas D.³, Chandran, Siddharthan¹

Source: PLoS ONE. 2008, Vol. 3 Issue 8, p1-8. 8p. 1 Diagram, 2 Graphs.

Subject Terms: *PROTEIN precursors, *FIBROBLAST growth factors, *BONE morphogenetic proteins, *SPINAL cord, *HEDGEHOG signaling proteins, *MITOGEN-activated protein kinases, *ASTROCYTES, *EMBRYOLOGY, *DEVELOPMENTAL neurobiology

T-box factors: targeting to chromatin and interaction with the histone H3 N-terminal tail.

Authors: Demay, Florence^1,2, Bilican, Bilada^1,3, Rodriguez, Mercedes¹, Carreira, Suzanne¹, Pontecorvi, Marco¹, Yan Ling¹, Goding, Colin R.¹ c.goding@mcri.ac.uk

Source: Pigment Cell Research. Aug2007, Vol. 20 Issue 4, p279-287. 9p. 5 Color Photographs, 4 Black and White Photographs, 1 Diagram.

Subject Terms: *TRANSCRIPTION factors, *MELANOMA, *NEUROENDOCRINE tumors, *CANCER, *CHROMATIN

Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations

Authors: Alami, Nael H., Smith, Rebecca B., Carrasco, Monica A., Williams, Luis A., Winborn, Christina S., Han, Steve S.W., Kiskinis, Evangelos, Winborn, Brett, Freibaum, Brian D., Kanagaraj, Anderson, Clare, Alison J., Badders, Nisha M., Bilican, Bilada, Chaum, Edward, Chandran, Siddharthan, Shaw, Christopher E., Eggan, Kevin C., Maniatis, Tom, Taylor, J. Paul

Source: In Neuron 5 February 2014 81(3):536-543

Unpicking neurodegeneration in a dish with human pluripotent stem cells

Authors: Bilican, Bilada, Serio, Andrea, Shaw, Christopher E, Maniatis, Tom, Chandran, Siddharthan

Source: Cell cycle. 12(15):2339-2340

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100050673436.0x000001&indx=1&recIds=ETOCvdc_100050673436.0x000001

Cell-mediated Neuroprotection in P301S Human Tau Transgenic Mice, a Model of Human Tauopathy

Authors: Hampton, David W., Webber, Daniel J., Bilican, Bilada, Goedert, Michel, Spillantini, Maria Grazia, Chandran, Siddharthan

Source: Alzheimer's & dementia. 6(4):e17-e18

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100066383730.0x000001&indx=1&recIds=ETOCvdc_100066383730.0x000001

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Evidence for evolutionary divergence of activity-dependent gene expression in developing neurons.

Authors: Jing Qiu, McQueen, Jamie, Bilican, Bilada, Dando, Owen, Magnani, Dario, Punovuori, Karolina, Selvaraj, Bhuvaneish T., Livesey, Matthew, Haghi, Ghazal, Heron, Samuel, Burr, Karen, Patani, Rickie, Rajan, Rinku, Sheppard, Olivia, Kind, Peter C., Simpson, T. Ian, Tybulewicz, Victor L. J., Wyllie, David J. A., Fisher, Elizabeth M. C., Lowell, Sally

Source: eLife; 2016, p1-15, 15p