A Mechanistic Study of the Feasibility of Ursodeoxycholic Acid in the Treatment of Colon Adenocarcinoma

Authors: Liu S, Zhou M, Huang X, Chen P, Li Q, Wang Y, Ge X, Wang F, Xu J, Gu J, Miao L, Deng X

Source: Drug Design, Development and Therapy, Vol Volume 19, Pp 1839-1852 (2025)

Subject Terms: ursodeoxycholic acid, colon adenocarcinoma treatment, bile acid metabolism, cell death., Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.dovepress.com/a-mechanistic-study-of-the-feasibility-of-ursodeoxycholic-acid-in-the--peer-reviewed-fulltext-article-DDDT; https://doaj.org/toc/1177-8881

Access URL: https://doaj.org/article/be0416a6a92e49bcb678c698c4082600

Integrating bioinformatics and metabolomics to identify potential biomarkers of hypertensive nephropathy

Authors: Kezhen Yang, Pingna Zhang, Xiaofeng Ding, Gong Yu, Jipeng Liu, Yi Yang, Jianqiao Fang, Qingguo Liu, Lu Zhang, Jianhua Li, Fangchao Wu

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-16 (2025)

Subject Terms: Bioinformatic, Metabolomics, Hypertensive nephropathy, Bile acid, Bile acid metabolism, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/a0ce414f208c483b85de8133021a5274

Ameliorative Effect of Hovenia dulcis Fruit Pedicel Polysaccharides on Alcohol-Induced Intestinal Injury in Mice Investigated Using 16S rRNA Sequencing and Metabolomics

Authors: ZHANG Yuchao, ZHU Sijie, LIU Liangyu, WANG Jianyun, ZHANG Jiaxin, SU Zexiong, CHEN Jiangyan, LIU Xudong

Source: Shipin Kexue, Vol 46, Iss 3, Pp 110-118 (2025)

Subject Terms: hovenia dulcis fruit pedicel polysaccharides, alcoholic intestinal injury, gut microbiota, bile acid metabolism, ameliorative effect, Food processing and manufacture, TP368-456

File Description: electronic resource

Relation: https://www.spkx.net.cn/fileup/1002-6630/PDF/2025-46-3-013.pdf; https://doaj.org/toc/1002-6630

Access URL: https://doaj.org/article/db85ace15e854b5cb60d3f3cd29fc790

Fecal bile acid profiles before and after fecal microbial transplant in pediatric onset ulcerative colitis

Authors: Kathleen Lo, Patil Kavarian, Beibei Wang, Riddhi Parsana, Ramon Durazo-Arvizu, Fengzhu Sun, Sonia Michail

Source: Gut Microbes Reports, Vol 1, Iss 1, Pp 1-12 (2024)

Subject Terms: Inflammatory bowel disease, bile acid metabolism, gut metabolites, Hispanic, clostridium difficile, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2993-3935

Access URL: https://doaj.org/article/55ed8dc4bd7f4f6c8d05dce826066639

Dietary high lipid and high plant-protein affected growth performance, liver health, bile acid metabolism and gut microbiota in groupers

Authors: Jia Xu, Fan Wang, Chaoqun Hu, Junxiang Lai, Shiwei Xie, Kefu Yu, Fajun Jiang

Source: Animal Nutrition, Vol 19, Iss , Pp 370-385 (2024)

Subject Terms: Liver damage, Lipid metabolism, Bile acid metabolism, Microbiota, Grouper, Animal culture, SF1-1100

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405654524001331; https://doaj.org/toc/2405-6545

Access URL: https://doaj.org/article/338ea003fb004db0bfaaa9c048eb826d

Dry ginger and Schisandra chinensis modulate intestinal flora and bile acid metabolism to treatment asthma

Authors: Yantong Yu, Shuang Geng, Chao Bu, Gang Cao, Yanquan Han, Dongmei Xie, Yan Hong

Source: Frontiers in Microbiology, Vol 16 (2025)

Subject Terms: inflammations, intestinal flora, bile acid metabolism, dry ginger, Schisandra chinensis, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmicb.2025.1541335/full; https://doaj.org/toc/1664-302X

Access URL: https://doaj.org/article/4c7815279e944c628e3d151195ee4651

Amentoflavone ameliorates DSS-induced ulcerative colitis via gut microbiota-bile acid metabolism axis modulation

Authors: Yuting Chen, Kaipeng Li, Meiyan Zhang, Jie Liu, Man Wang, Yuhan Xiu, Qiaoyue Zhang, Ding Zhao

Source: Journal of Functional Foods, Vol 126, Iss , Pp 106706- (2025)

Subject Terms: Amentoflavone, Ulcerative colitis, Gut microbiota, Bile acid metabolism, Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1756464625000489; https://doaj.org/toc/1756-4646

Access URL: https://doaj.org/article/d0fb7e399b0447daa330cbe23c5bc712

Regulatory role of S1P and its receptors in sepsis-induced liver injury

Authors: Bin Wang, Xiaoyu Wu, Jiangfeng Cheng, Junming Ye, Hongquan Zhu, Xiaofeng Liu

Source: Frontiers in Immunology, Vol 16 (2025)

Subject Terms: S1P, S1PRs, sepsis, immune, bile acid metabolism, liver-intestinal circulation, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2025.1489015/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/fafeb0ca3513432a90473b16d716a4db

Oligomeric procyanidins combined with Parabacteroides distasonis ameliorate high-fat diet-induced atherosclerosis by regulating lipid metabolism, inflammation reaction and bile acid metabolism in ApoE-/- mice

Authors: Mingjuan Xu, Cheng Lü, Yiqing Hu, Mo Zhang, Jinxin Shen, Chunyi Liu, Qun Lu, Rui Liu

Source: Food Science and Human Wellness, Vol 13, Iss 5, Pp 2847-2856 (2024)

Subject Terms: atherosclerosis, pararabacteroides distasonis, oligomeric procyanidins, reverse cholesterol transport, bile acid metabolism, Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: https://www.sciopen.com/article/10.26599/FSHW.2022.9250230; https://doaj.org/toc/2097-0765; https://doaj.org/toc/2213-4530

Access URL: https://doaj.org/article/7a173093347542aaa3126d5538a42d8c

Dietary silymarin improves performance by altering hepatic lipid metabolism and cecal microbiota function and its metabolites in late laying hens

Authors: Yanghao Guo, Yudong Xu, Derun Wang, Shihao Yang, Zehe Song, Rui Li, Xi He

Source: Journal of Animal Science and Biotechnology, Vol 15, Iss 1, Pp 1-18 (2024)

Subject Terms: Bile acid metabolism, Cecal microbiota, Laying hen, Lipid metabolism, Lipoproteins, Silymarin, Animal culture, SF1-1100, Veterinary medicine, SF600-1100

File Description: electronic resource

Relation: https://doaj.org/toc/2049-1891

Access URL: https://doaj.org/article/3535246ae4cc49d480bd9576e1a40f2f

Emodin alleviates cholestatic liver injury by modulating Sirt1/Fxr signaling pathways

Authors: Zhi Hu, Xiaohua Cheng, Jun Cai, Chao Huang, Jinfang Hu, Jianming Liu

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)

Subject Terms: Emodin, Cholestatic liver injury, Sirtuin1 (Sirt1), Farnesoid x receptor (Fxr), Bile acid metabolism, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/99ba29c880a7474cb170cf025f64f9c1

Synthesis of Natural Products Using Engineered Plants and Microorganisms

Contributors: Wei, Yongjun, Qu, Lingbo, Ji, Xiao-Jun

Subject Terms: Citrus reticulata ‘chachi’, transcriptome, metabolome, flavonoid, Artemisia annua, artemisinin, synthetic biology, genetic engineering, transcription factor, Ganoderma luteomarginatum, lanostane triterpenoids, ergostane steroids, cytotoxic activity, excision wound, epithelization, essential oils, wound healing, biological nano selenium, nutritional composition, antioxidant stress, organic selenium, ABC transporter family, Epimedium, flavonoids, pharmacological activities, extraction methods, biotransformation, biosynthesis, L-cysteine, metabolic engineering, fermentation, fed-batch process, downstream processing, Ardisiae Japonicae Herba, anti-acute lung injury, UPLC–Orbitrap Fusion–MS, active compounds, ginsenoside Rb1, ginsenoside CK, ginsenoside PPD, hyperlipidemia, gut microbiota, bile acid metabolism, lignin linkages, Klebsiella aerogenes, lignocellulose, catalytic mechanism, Lycium ruthenicum Murray, extraction and identification methods, bioactivities, applied research, PLP, NADPH, 1,4-diaminobutane, cofactor, synanthropic herbaceous plants, endophytic bacteria, biologically active compounds, biosynthetic gene clusters, Research and information: general, Biology, life sciences, Zoology and animal sciences

File Description: application/octet-stream

Access URL: https://directory.doabooks.org/handle/20.500.12854/152989
https://mdpi.com/books/pdfview/book/10207

Sedanolide alleviates DSS-induced colitis by modulating the intestinal FXR-SMPD3 pathway in mice

Authors: Li, Shengjie ^{a, 1}, Zhuge, Aoxiang ^{a, 1}, Chen, Hui ^{a, 1}, Han, Shengyi ^a, Shen, Jian ^a, Wang, Kaicen ^a, Xia, Jiafeng ^a, Xia, He ^a, Jiang, Shiman ^a, Wu, Youhe ^a, Li, Lanjuan ^{a, b, ⁎}

Source: In Journal of Advanced Research March 2025 69:413-426

Polysaccharide extracted from Phellinus igniarius attenuated hyperuricemia by modulating bile acid metabolism and inhibiting uric acid synthesis in adenine/potassium oxonate-treated mice

Authors: Gan, Yuhan ^{a, c, 1}, Zeng, Yuting ^{b, 1}, Huang, Jingyi ^c, Li, Yuxi ^c, Zhu, Qing ^{c, ⁎⁎}, Wang, Lei ^{a, ⁎}

Source: In Journal of Ethnopharmacology 27 February 2025 342

Pharmacodynamic material basis of licorice and mechanisms of modulating bile acid metabolism and gut microbiota in cisplatin-induced liver injury based on LC-MS and network pharmacology analysis

Authors: Li, Jie ^{a, 1}, Lian, Xiaolong ^{c, 1}, Li, Baojian ^b, Ma, Quhuan ^a, Yang, Lingling ^a, Gao, Guangmiao ^a, Yin, Tingmei ^a, Fu, Xiaoyan ^a, Deng, Yi ^{a, ⁎}, Yang, Zhijun ^{a, ⁎⁎}, Yang, Xiujuan ^{a, ⁎⁎⁎}

Source: In Journal of Ethnopharmacology 31 January 2025 340

Multiomics analysis elucidated the role of inflammatory response and bile acid metabolism disturbance in electric shock-induced liver injury in mice

Authors: Zhang, Wenjuan ^{a, 1}, Yin, Luncai ^{b, 1}, Wang, Hui ^{c, 1}, Long, Ce ^d, Liu, Jin ^e, Deng, Ping ^a, Yue, Yang ^a, Li, Jingdian ^a, He, Mindi ^a, Lu, Yonghui ^a, Luo, Yan ^a, Chen, Siyu ^a, Tao, Jiawen ^a, Tian, Li ^a, Xie, Jia ^a, Chen, Mengyan ^a, Yu, Zhengping ^a, Zhou, Zhou ^f, Gao, Peng ^a, Pi, Huifeng ^{a, g, ⁎}

Source: In Chinese Journal of Traumatology August 2024

Tea intervention ameliorated metabolic dysfunction caused by circadian rhythm disorders via gut microbiota-bile acid-FXR axis

Authors: Yang Wei, Siwei Miao, Kang Wei, Lanlan Peng, Xinlin Wei

Source: Journal of Functional Foods, Vol 123, Iss , Pp 106566- (2024)

Subject Terms: Tea, Circadian rhythm disorder, Metabolic dysfunction, Gut microbiota, Bile acid metabolism, Farnesoid X receptor, Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1756464624005693; https://doaj.org/toc/1756-4646

Access URL: https://doaj.org/article/ee26fcd5841e403a818b890886110960

Integrated multi-omics reveal gut microbiota-mediated bile acid metabolism alteration regulating immunotherapy responses to anti-α4β7-integrin in Crohn’s disease

Authors: Bing Han, Daiyuan Tang, Xiaodan Lv, Junhua Fan, Shiquan Li, Hui Zhu, Jiatong Zhang, Shang Xu, Xiaofang Xu, Ziqian Huang, Zhixi Huang, Guangfu Lin, Lingling Zhan, Xiaoping Lv

Source: Gut Microbes, Vol 16, Iss 1 (2024)

Subject Terms: Gut microbiota, bile acid metabolism, biomarker, Crohn’s disease, immunotherapy responses, Anti-α4β7-integrin, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1949-0976; https://doaj.org/toc/1949-0984

Access URL: https://doaj.org/article/9a8443b3d1dd41d283d98b3bcabe12c9

Restricted intake of sulfur-containing amino acids reversed the hepatic injury induced by excess Desulfovibrio through gut–liver axis

Authors: Lingxi Zhou, Gexue Lu, Yawen Nie, Yilin Ren, Jin-Song Shi, Yuzheng Xue, Zheng-Hong Xu, Yan Geng

Source: Gut Microbes, Vol 16, Iss 1 (2024)

Subject Terms: Gut microbiota, liver–gut axis, Desulfovibrio, purified diet, bile acid metabolism, sulfur-containing amino acids, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1949-0976; https://doaj.org/toc/1949-0984

Access URL: https://doaj.org/article/ce7847908d8143beb7afa5c8cc0389e7

Bacteroides fragilis alleviates necrotizing enterocolitis through restoring bile acid metabolism balance using bile salt hydrolase and inhibiting FXR-NLRP3 signaling pathway

Authors: Zhenhui Chen, Huijuan Chen, Wanwen Huang, Xiaotong Guo, Lu Yu, Jiamin Shan, Xiaoshi Deng, Jiaxin Liu, Wendan Li, Wei Shen, Hongying Fan

Source: Gut Microbes, Vol 16, Iss 1 (2024)

Subject Terms: Necrotizing enterocolitis, bile acid metabolism, FXR, NLRP3, B. fragilis, BSH, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1949-0976; https://doaj.org/toc/1949-0984

Access URL: https://doaj.org/article/f815df516dc94567855e394766687efc