Integrated proteomics and metabolomics analyses reveal new insights into the antitumor effects of valproic acid plus simvastatin combination in a prostate cancer xenograft model associated with downmodulation of YAP/TAZ signaling

Authors: Federica Iannelli, Rita Lombardi, Susan Costantini, Maria Serena Roca, Laura Addi, Francesca Bruzzese, Elena Di Gennaro, Alfredo Budillon, Biagio Pucci

Source: Cancer Cell International, Vol 24, Iss 1, Pp 1-15 (2024)

Subject Terms: Drug repurposing, Valproic acid, Simvastatin, Proteomics, Metabolomics, Prostate cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2867

Access URL: https://doaj.org/article/6a8ebb7193df4874996367e1308370ea

HSP90 identified by a proteomic approach as druggable target to reverse platinum resistance in ovarian cancer

Authors: Rita Lombardi, Maura Sonego, Biagio Pucci, Laura Addi, Federica Iannelli, Francesca Capone, Luigi Alfano, Maria Serena Roca, Maria Rita Milone, Tania Moccia, Alice Costa, Elena Di Gennaro, Francesca Bruzzese, Gustavo Baldassarre, Alfredo Budillon

Source: Molecular Oncology, Vol 15, Iss 4, Pp 1005-1023 (2021)

Subject Terms: cisplatin, drug resistance, HSP90, ovarian cancer, proteomics, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

Access URL: https://doaj.org/article/b460b33c2f544783a77170d47c26337c

Synergistic antitumor interaction of valproic acid and simvastatin sensitizes prostate cancer to docetaxel by targeting CSCs compartment via YAP inhibition

Authors: Federica Iannelli, Maria Serena Roca, Rita Lombardi, Chiara Ciardiello, Laura Grumetti, Simona De Rienzo, Tania Moccia, Carlo Vitagliano, Angela Sorice, Susan Costantini, Maria Rita Milone, Biagio Pucci, Alessandra Leone, Elena Di Gennaro, Rita Mancini, Gennaro Ciliberto, Francesca Bruzzese, Alfredo Budillon

Source: Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-24 (2020)

Subject Terms: Valproic acid, Statin, Mevalonate pathway, YAP, Prostate cancer, Cancer stem cells, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13046-020-01723-7; https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/e79dabb2f2a0410392c345de926e0f74

Large oncosomes overexpressing integrin alpha-V promote prostate cancer adhesion and invasion via AKT activation

Authors: Chiara Ciardiello, Alessandra Leone, Paola Lanuti, Maria S. Roca, Tania Moccia, Valentina R. Minciacchi, Michele Minopoli, Vincenzo Gigantino, Rossella De Cecio, Massimo Rippa, Lucia Petti, Francesca Capone, Carlo Vitagliano, Maria R. Milone, Biagio Pucci, Rita Lombardi, Federica Iannelli, Elena Di Gennaro, Francesca Bruzzese, Marco Marchisio, Maria V. Carriero, Dolores Di Vizio, Alfredo Budillon

Source: Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-16 (2019)

Subject Terms: Extracellular vesicles, Oncosomes, Prostate cancer, Alpha-V integrin, AKT, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13046-019-1317-6; https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/df0b835cb5874271a1a89640e6d4f5e9

Proteomic characterization of peroxisome proliferator‐activated receptor‐γ (PPARγ) overexpressing or silenced colorectal cancer cells unveils a novel protein network associated with an aggressive phenotype

Authors: Maria Rita Milone, Biagio Pucci, Tommaso Colangelo, Rita Lombardi, Federica Iannelli, Vittorio Colantuoni, Lina Sabatino, Alfredo Budillon

Source: Molecular Oncology, Vol 10, Iss 8, Pp 1344-1362 (2016)

Subject Terms: Peroxisome proliferator-activated receptor gamma, Colorectal cancer, Proteomics, Ingenuity pathway analysis, 2-D DIGE, Mass spectrometry, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

Access URL: https://doaj.org/article/5ae5e0d1419249a9988f3822d21263f4

Evaluation of Selenite Effects on Selenoproteins and Cytokinome in Human Hepatoma Cell Lines

Authors: Susan Costantini, Giuseppe Castello, Gianni Di Bernardo, Melissa Nazzaro, Maria Grazia Volpe, Francesca Capone, Eliana Guerriero, Maria Rita Milone, Giovanni Colonna, Biagio Pucci, Fabiola Rusolo

Source: Molecules, Vol 18, Iss 3, Pp 2549-2562 (2013)

Subject Terms: selenite, SELENBP1, SELK, GPX1, HepG2, Huh7, hepatocarcinoma, cytokines, interactomics, inflammation, Organic chemistry, QD241-441

File Description: electronic resource

Relation: http://www.mdpi.com/1420-3049/18/3/2549; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/7887503dec284f458088d789ce8f37fe

A novel DNA helicase with strand-annealing activity from the crenarchaeon Sulfolobus solfataricus.

Authors: Mariarita De felice, Valentina Aria, Luca Esposito, Mariarosaria De falco, Biagio Pucci, Mosè Rossi, Francesca M. Pisani

Source: Biochemical Journal; 2007, Vol. 408 Issue 1, p87-95, 9p

Subject Terms: DNA replication, DNA synthesis, PROTEINS, GENOMES, DATABASES, DNA helicases, ESCHERICHIA coli

Martyrdom of Saint Agathe
Martyrium der heiligen Agathe

Authors: Rigamonti (photographer) (shot), Biagio Puccini (painter) (production), Rigamonti (Fotograf) (Aufnahme), Biagio Puccini (Maler) (Herstellung)

Availability: http://data.europeana.eu/aggregation/europeana/366/item_WW5ZH6Q6TCCEJUFFTKXKNO5SCU66D5CZ

Die Heilige Trinität und Maria Immaculata
Saint Trinity and Mary Immaculata

Authors: Fontolan, Enrico (Fotograf) (Aufnahme), Biagio Puccini (Maler) (Herstellung), Fontolan, Enrico (photographer) (shot), Biagio Puccini (painter) (production)

Availability: http://data.europeana.eu/aggregation/europeana/366/item_AMSU4Z3NPXQMDJZXT3DKMQE4BCIKJOOW