Plasma metabolome reveals altered oxidative stress, inflammation, and amino acid metabolism in dogs with idiopathic epilepsy.

Authors: Verdoodt, Fien^1,2,3 (AUTHOR), Bhatti, Sofie F. M.² (AUTHOR), Molina, Jenifer⁴ (AUTHOR), Van Ham, Luc² (AUTHOR), Vanhaecke, Lynn³ (AUTHOR), Junius, Greet⁵ (AUTHOR), Hemeryck, Lieselot Y.³ (AUTHOR), Hesta, Myriam¹ (AUTHOR) myriam.hesta@ugent.be

Source: Epilepsia (Series 4). Apr2025, Vol. 66 Issue 4, p1315-1328. 14p.

Subject Terms: *OXIDATIVE stress, *INFLAMMATION, *CELL metabolism, *VITAMIN B6, *EPILEPSY, *DOGS, *AMINO acid metabolism, *METABOLOMIC fingerprinting

Genetic counseling in veterinary medicine: towards an evidence-based definition for the small animal practice.

Authors: Adant, Laura, Szymczak, Virginie, Bhatti, Sofie F. M., Smets, Pascale, Saunders, Jimmy, Peelman, Luc, Broeckx, Bart J. G.

Source: BMC Veterinary Research; 2/22/2025, Vol. 21 Issue 1, p1-12, 12p

Subject Terms: GENETIC counseling, MEDICAL genetics, VETERINARY medicine, SCIENTIFIC literature, ANIMAL breeders

VariantscanR: an R-package as a clinical tool for variant filtering of known phenotype-associated variants in domestic animals.

Authors: Boeykens, Fréderique¹ (AUTHOR) frederique.boeykens@ugent.be, Bhatti, Sofie F. M.² (AUTHOR), Peelman, Luc¹ (AUTHOR), Broeckx, Bart J. G.¹ (AUTHOR) bart.broeckx@ugent.be

Source: BMC Bioinformatics. 8/1/2023, Vol. 24 Issue 1, p1-15. 15p.

Subject Terms: *MEDICAL genetics, *ANIMAL genetics, *GENETIC variation, *NUCLEOTIDE sequencing, *QUALITY control

Tremors in cats with hepatic encephalopathy‐congenital portosystemic shunts or postattenuation neurological syndrome.

Authors: Liatis, Theofanis, Bhatti, Sofie F. M., Glanemann, Barbara, De Decker, Steven

Source: Veterinary Record: Journal of the British Veterinary Association; 1/4/2025, Vol. 196 Issue 1, p1-5, 5p

Subject Terms: MAGNETIC resonance imaging, HEPATIC encephalopathy, VIDEO recording, TREMOR, MEDICAL records

Spinal arachnoid diverticula in cats: Clinical presentation, diagnostic imaging findings, treatment, and outcome.

Authors: De Frias, João Miguel^1,2 (AUTHOR) joao.frias@ed.ac.uk, Bhatti, Sofie F. M.³ (AUTHOR), Nye, George⁴ (AUTHOR), Gonçalves, Rita⁵ (AUTHOR), Harcourt‐Brown, Tom⁶ (AUTHOR), Fadda, Angela⁶ (AUTHOR), Marioni‐Henry, Katia² (AUTHOR), Padley, Hannah⁷ (AUTHOR), De Decker, Steven¹ (AUTHOR)

Source: Journal of Veterinary Internal Medicine. Jan/Feb2025, Vol. 39 Issue 1, p1-6. 6p.

Subject Terms: *ARACHNOID cysts, *MAGNETIC resonance imaging, *CAT diseases, *FECAL incontinence, *SPINE diseases

Identification of a Novel Idiopathic Epilepsy Risk Locus and a Variant in the CCDC85A Gene in the Dutch Partridge Dog.

Authors: Beckers, Evy¹ (AUTHOR), Bhatti, Sofie F. M.² (AUTHOR), Van Poucke, Mario¹ (AUTHOR), Polis, Ingeborgh² (AUTHOR), Farnir, Frédéric³ (AUTHOR), Van Nieuwerburgh, Filip⁴ (AUTHOR), Mandigers, Paul⁵ (AUTHOR), Van Ham, Luc² (AUTHOR), Peelman, Luc¹ (AUTHOR), Broeckx, Bart J. G.¹ (AUTHOR) bart.broeckx@ugent.be

Source: Animals (2076-2615). Mar2023, Vol. 13 Issue 5, p810. 17p.

Subject Terms: *GENETIC variation, *DOG breeds, *GENOME-wide association studies, *RNA splicing, *LOCUS (Genetics), *DOGS, *EPILEPSY, *PARTRIDGES

Episodic mandibular tremor in dogs: an idiopathic movement disorder or a manifestation of pain.

Authors: Liatis, Theofanis¹ theofanis.liatis@gmail.com, Bhatti, Sofie F. M.², Aguilera, Albert³, Makri, Nikoleta³, Batla, Amit⁴, Scarpante, Elena⁵, Park, Joon⁶, De Decker, Steven¹

Source: Journal of the American Veterinary Medical Association. Oct2024, Vol. 262 Issue 10, p1363-1369. 7p.

Subject Terms: *DOGS, *MOVEMENT disorders, *IDIOPATHIC diseases, *PETS, *TREMOR, *HOSPITAL surveys, *DEEP brain stimulation, BRITISH kings & rulers

Exonisation of an intronic L1 element in the dystrophin gene associated with X‐linked muscular dystrophy in a Border Collie dog.

Authors: Van Poucke, Mario, Ledeganck, Liesbet, Guo, Ling T., Shelton, G. Diane, Bhatti, Sofie F. M., Cornelis, Ine, Peelman, Luc

Source: Animal Genetics; Oct2024, Vol. 55 Issue 5, p733-743, 11p

Subject Terms: DYSTROPHIN genes, MUSCULAR dystrophy, CREATINE kinase, ELECTROMYOGRAPHY, DYSTROPHIN

Generalized myoclonic epilepsy with photosensitivity in juvenile dogs caused by a defective DIRAS family GTPase 1

Authors: Wielaender, Franziska, Sarviaho, Riika, James, Fiona, Hytönen, Marjo K., Cortez, Miguel A., Kluger, Gerhard, Koskinen, Lotta L. E., Arumilli, Meharji, Kornberg, Marion, Bathen-Noethen, Andrea, Tipold, Andrea, Rentmeister, Kai, Bhatti, Sofie F. M., Hülsmeyer, Velia, Boettcher, Irene C., Tästensen, Carina, Flegel, Thomas, Dietschi, Elisabeth, Leeb, Tosso, Matiasek, Kaspar, Fischer, Andrea, Lohi, Hannes

Source: Proceedings of the National Academy of Sciences of the United States of America, 2017 Mar 01. 114(10), 2669-2674.

Access URL: https://www.jstor.org/stable/26480087

Idiopathic and structural episodic nonintentional head tremor in dogs: 100 cases (2004‐2022).

Authors: Liatis, Theofanis¹ (AUTHOR) theofanis.liatis@gmail.com, Bhatti, Sofie F. M.² (AUTHOR), Dyrka, Magdalena³ (AUTHOR), Gutierrez‐Quintana, Rodrigo³ (AUTHOR), Gonçalves, Rita⁴ (AUTHOR), Madden, Megan⁵ (AUTHOR), De Decker, Steven¹ (AUTHOR)

Source: Journal of Veterinary Internal Medicine. Nov/Dec2023, Vol. 37 Issue 6, p2301-2309. 9p.

Subject Terms: *ESSENTIAL tremor, *TREMOR, *DOGS, *MAGNETIC resonance imaging, *BRAIN damage

Generalized myokymia, or neuromyotonia, or both in dogs with or without spinocerebellar ataxia.

Authors: Vanhaesebrouck, An, Van Poucke, Mario, Stee, Kimberley, Granger, Nicolas, Ives, Edward, Van Soens, Iris, Cornelis, Ine, Bossens, Kenny, Peelman, Luc, Van Ham, Luc, Bhatti, Sofie F. M.

Source: Journal of Veterinary Internal Medicine; Nov/Dec2023, Vol. 37 Issue 6, p2310-2314, 5p

Subject Terms: ISAACS syndrome, DOGS, SYMPTOMS, CEREBELLUM degeneration, GENETIC variation, FRIEDREICH'S ataxia, SPINOCEREBELLAR ataxia

Serum anti‐GM2 and anti‐GalNAc‐GD1a ganglioside IgG antibodies are biomarkers for immune‐mediated polyneuropathies in cats.

Authors: Halstead, Susan K., Jackson, Mark, Bianchi, Ezio, Rupp, Stefan, Granger, Nicolas, Menchetti, Marika, Galli, Greta, Freeman, Paul, Kaczmarska, Adriana, Bhatti, Sofie F. M., Brocal, Josep, José‐López, Roberto, Tipold, Andrea, Gutierrez Quintana, Rodrigo, Ives, Edward J., Liatis, Theofanis, Nessler, Jasmin, Rusbridge, Clare, Willison, Hugh J., Rupp, Angie

Source: Journal of the Peripheral Nervous System; Mar2023, Vol. 28 Issue 1, p32-40, 9p

Subject Terms: BLOOD testing, BIOMARKERS, IMMUNOGLOBULINS, PREDICTIVE tests, ANIMAL experimentation, CATS, POLYNEUROPATHIES, DESCRIPTIVE statistics, RESEARCH funding, SENSITIVITY & specificity (Statistics), LIPIDS

Spinocerebellar ataxia in the Bouvier des Ardennes breed is caused by a KCNJ10 missense variant.

Authors: Stee, Kimberley, Van Poucke, Mario, Pumarola, Martí, Geerinckx, Lise, Van Soens, Iris, Bhatti, Sofie F. M., Peelman, Luc, Cornelis, Ine

Source: Journal of Veterinary Internal Medicine; Jan2023, Vol. 37 Issue 1, p216-222, 7p

Subject Terms: SPINOCEREBELLAR ataxia, MISSENSE mutation, FRIEDREICH'S ataxia, PUPPIES, CEREBELLUM degeneration, CEREBELLAR ataxia

A Nonsense Variant in the DMD Gene Causes X-Linked Muscular Dystrophy in the Maine Coon Cat.

Authors: Beckers, Evy, Cornelis, Ine, Bhatti, Sofie F. M., Smets, Pascale, Shelton, G. Diane, Guo, Ling T., Peelman, Luc, Broeckx, Bart J. G.

Source: Animals (2076-2615); Nov2022, Vol. 12 Issue 21, p2928, 12p

Subject Terms: MUSCULAR dystrophy, RACCOON, GENETIC variation, GROWTH disorders, CREATINE kinase, FACIOSCAPULOHUMERAL muscular dystrophy, FAMILIAL spastic paraplegia

SLC25A12 Missense Variant in Nova Scotia Duck Tolling Retrievers Affected by Cerebellar Degeneration—Myositis Complex (CDMC).

Authors: Christen, Matthias, Rupp, Stefan, Van Soens, Iris, Bhatti, Sofie F. M., Matiasek, Kaspar, von Klopmann, Thilo, Jagannathan, Vidhya, Madden, Indiana, Batcher, Kevin, Bannasch, Danika, Leeb, Tosso

Source: Genes; Jul2022, Vol. 13 Issue 7, p1223-1223, 7p

Subject Terms: CEREBELLUM degeneration, DOGS, MISSENSE mutation, DYSPLASIA, PUPPIES, MYOSITIS, GENE frequency

International Veterinary Epilepsy Task Force consensus proposal: medical treatment of canine epilepsy in Europe.

Authors: Bhatti, Sofie F. M.¹ sofie.bhatti@ugent.be, De Risio, Luisa², Muñana, Karen³, Penderis, Jacques⁴, Stein, Veronika M.⁵, Tipold, Andrea⁵, Berendt, Mette⁶, Farquhar, Robyn G.⁷, Fischer, Andrea⁸, Long, Sam⁹, Löscher, Wolfgang¹⁰, Mandigers, Paul J. J.¹¹, Matiasek, Kaspar¹², Pakozdy, Akos¹³, Patterson, Edward E.¹⁴, Platt, Simon¹⁵, Podell, Michael¹⁶, Potschka, Heidrun¹⁷, Rusbridge, Clare^18,19, Volk, Holger A.²⁰

Source: BMC Veterinary Research. 9/3/2015, Vol. 11 Issue 1, p1-16. 16p.

Subject Terms: *EPILEPSY in animals, *DOG diseases, *ANTICONVULSANTS, *VETERINARY medicine, *VETERINARY therapeutics

Geographic Terms: EUROPE

Primary orthostatic tremor and orthostatic tremor‐plus in dogs: 60 cases (2003‐2020).

Authors: Liatis, Theofanis, Gutierrez‐Quintana, Rodrigo, Mari, Lorenzo, Czopowicz, Michał, Polidoro, Dakir, Bhatti, Sofie F. M., Cozzi, Francesca, Tirrito, Federica, Brocal, Josep, José‐López, Roberto, Kaczmarska, Adriana, Cappello, Rodolfo, Harris, Georgina, Alves, Lisa, Rusbridge, Clare, Rossmeisl, John H.

Source: Journal of Veterinary Internal Medicine; Jan2022, Vol. 36 Issue 1, p179-189, 11p

Subject Terms: PHENOBARBITAL, DOG breeds, TREMOR, SYMPTOMS, NEUROLOGICAL disorders, DOG breeding, DOGS

Clinical and diagnostic findings in a dog and a cat with congenital hypothyroidism.

Authors: Hermans, Michelle, Burger, Nienke Christina, Kromhout, Kaatje, Bhatti, Sofie F. M., Cornelis, Ine

Source: Veterinary Record Case Reports; 12/8/2020, p1-7, 7p

Repetitive transcranial magnetic stimulation in drug‐resistant idiopathic epilepsy of dogs: A noninvasive neurostimulation technique.

Authors: Charalambous, Marios, Van Ham, Luc, Broeckx, Bart J. G., Roggeman, Tom, Carrette, Sofie, Vonck, Kristi, Kervel, Roelof R., Cornelis, Ine, Bhatti, Sofie F. M.

Source: Journal of Veterinary Internal Medicine; Nov2020, Vol. 34 Issue 6, p2555-2561, 7p

Subject Terms: TRANSCRANIAL magnetic stimulation, NEURAL stimulation, EPILEPSY, CLINICAL trials, SEIZURES (Medicine)

Phenotypic characterization of paroxysmal dyskinesia in Maltese dogs.

Authors: Polidoro, Dakir, Van Ham, Luc, Santens, Patrick, Cornelis, Ine, Charalambous, Marios, Broeckx, Bart J. G., Bhatti, Sofie F. M.

Source: Journal of Veterinary Internal Medicine; Jul2020, Vol. 34 Issue 4, p1541-1546, 6p

Subject Terms: DOG breeds, CENTRAL nervous system diseases, DOGS, GLUTEN-free foods, DOG owners, DYSKINESIAS, DYSTONIA, INVOLUNTARY hospitalization