Alzheimer Disease Detection from Raman Spectroscopy of the Cerebrospinal Fluid via Topological Machine Learning

Authors: Conti, Francesco, Banchelli, Martina, Bessi, Valentina, Cecchi, Cristina, Chiti, Fabrizio, Colantonio, Sara, D'Andrea, Cristiano, de Angelis, Marella, Moroni, Davide, Nacmias, Benedetta, Pascali, Maria Antonietta, Sorbi, Sandro, Matteini, Paolo

Subject Terms: Computer Science - Machine Learning, 55N31 (primary), 55N35 (secondary), I.2.6, I.5

Access URL: http://arxiv.org/abs/2309.03664

Harnessing topological machine learning in Raman spectroscopy: Perspectives for Alzheimer’s disease detection via cerebrospinal fluid analysis

Authors: Conti, Francesco, Banchelli, Martina, Bessi, Valentina, Cecchi, Cristina, Chiti, Fabrizio, Colantonio, Sara, D’Andrea, Cristiano, de Angelis, Marella, Moroni, Davide, Nacmias, Benedetta, Pascali, Maria Antonietta, Sorbi, Sandro, Matteini, Paolo

Source: In Journal of the Franklin Institute December 2024 361(18)

Genome-wide analyses reveal a potential role for the MAPT, MOBP, and APOE loci in sporadic frontotemporal dementia

Authors: Manzoni, Claudia, Kia, Demis A., Ferrari, Raffaele, Leonenko, Ganna, Costa, Beatrice, Saba, Valentina, Jabbari, Edwin, Tan, Manuela MX., Albani, Diego, Alvarez, Victoria, Alvarez, Ignacio, Andreassen, Ole A., Angiolillo, Antonella, Arighi, Andrea, Baker, Matt, Benussi, Luisa, Bessi, Valentina, Binetti, Giuliano, Blackburn, Daniel J., Boada, Merce, Boeve, Bradley F., Borrego-Ecija, Sergi, Borroni, Barbara, Bråthen, Geir, Brooks, William S., Bruni, Amalia C., Caroppo, Paola, Bandres-Ciga, Sara, Clarimon, Jordi, Colao, Rosanna, Cruchaga, Carlos, Danek, Adrian, de Boer, Sterre CM., de Rojas, Itziar, di Costanzo, Alfonso, Dickson, Dennis W., Diehl-Schmid, Janine, Dobson-Stone, Carol, Dols-Icardo, Oriol, Donizetti, Aldo, Dopper, Elise, Durante, Elisabetta, Ferrari, Camilla, Forloni, Gianluigi, Frangipane, Francesca, Fratiglioni, Laura, Kramberger, Milica G., Galimberti, Daniela, Gallucci, Maurizio, García-González, Pablo, Ghidoni, Roberta, Giaccone, Giorgio, Graff, Caroline, Graff-Radford, Neill R., Grafman, Jordan, Halliday, Glenda M., Hernandez, Dena G., Hjermind, Lena E., Hodges, John R., Holloway, Guy, Huey, Edward D., Illán-Gala, Ignacio, Josephs, Keith A., Knopman, David S., Kristiansen, Mark, Kwok, John B., Leber, Isabelle, Leonard, Hampton L., Libri, Ilenia, Lleo, Alberto, Mackenzie, Ian R., Madhan, Gaganjit K., Maletta, Raffaele, Marquié, Marta, Maver, Ales, Menendez-Gonzalez, Manuel, Milan, Graziella, Miller, Bruce L., Morris, Christopher M., Morris, Huw R., Nacmias, Benedetta, Newton, Judith, Nielsen, Jørgen E., Nilsson, Christer, Novelli, Valeria, Padovani, Alessandro, Pal, Suvankar, Pasquier, Florence, Pastor, Pau, Perneczky, Robert, Peterlin, Borut, Petersen, Ronald C., Piguet, Olivier, Pijnenburg, Yolande AL., Puca, Annibale A., Rademakers, Rosa, Rainero, Innocenzo, Reus, Lianne M., Richardson, Anna MT., Riemenschneider, Matthias, Rogaeva, Ekaterina, Rogelj, Boris, Rollinson, Sara, Rosen, Howard, Rossi, Giacomina, Rowe, James B., Rubino, Elisa, Ruiz, Agustin, Salvi, Erika, Sanchez-Valle, Raquel, Sando, Sigrid Botne, Santillo, Alexander F., Saxon, Jennifer A., Schlachetzki, Johannes CM., Scholz, Sonja W., Seelaar, Harro, Seeley, William W., Serpente, Maria, Sorbi, Sandro, Sordon, Sabrina, St George-Hyslop, Peter, Thompson, Jennifer C., Van Broeckhoven, Christine, Van Deerlin, Vivianna M., Van der Lee, Sven J., Van Swieten, John, Tagliavini, Fabrizio, van der Zee, Julie, Veronesi, Arianna, Vitale, Emilia, Waldo, Maria Landqvist, Yokoyama, Jennifer S., Nalls, Mike A., Momeni, Parastoo, Singleton, Andrew B., Hardy, John, Escott-Price, Valentina

Source: In The American Journal of Human Genetics 11 July 2024 111(7):1316-1329

Data-driven subtypes of mixed semantic-logopenic primary progressive aphasia: Linguistic features, biomarker profiles and brain metabolic patterns

Authors: Mazzeo, Salvatore, Morinelli, Carmen, Polito, Cristina, Giacomucci, Giulia, Moschini, Valentina, Ingannato, Assunta, Balestrini, Juri, Frigerio, Daniele, Emiliani, Filippo, Galdo, Giulia, Crucitti, Chiara, Piazzesi, Diletta, Bagnoli, Silvia, Padiglioni, Sonia, Berti, Valentina, Sorbi, Sandro, Nacmias, Benedetta, Bessi, Valentina

Source: In Journal of the Neurological Sciences 15 May 2024 460

Disentangling empathy impairment along Alzheimer's disease continuum: From subjective cognitive decline to Alzheimer's dementia

Authors: Giacomucci, Giulia, Moschini, Valentina, Piazzesi, Diletta, Padiglioni, Sonia, Caruso, Cecilia, Nuti, Claudia, Munarin, Alice, Mazzeo, Salvatore, Galdo, Giulia, Polito, Cristina, Emiliani, Filippo, Frigerio, Daniele, Morinelli, Carmen, Bagnoli, Silvia, Ingannato, Assunta, Nacmias, Benedetta, Sorbi, Sandro, Berti, Valentina, Bessi, Valentina

Source: In Cortex March 2024 172:125-140

Plasma p-tau181 as a promising non-invasive biomarker of Alzheimer's Disease pathology in Subjective Cognitive Decline and Mild Cognitive Impairment

Authors: Giacomucci, Giulia, Mazzeo, Salvatore, Crucitti, Chiara, Ingannato, Assunta, Bagnoli, Silvia, Padiglioni, Sonia, Galdo, Giulia, Emiliani, Filippo, Frigerio, Daniele, Moschini, Valentina, Morinelli, Carmen, Sorbi, Sandro, Bessi, Valentina, Nacmias, Benedetta

Source: In Journal of the Neurological Sciences 15 October 2023 453

Motivation, acceptability and attitudes toward lung cancer screening among persons who attend a tobacco cessation program: A multicenter survey in Italy

Authors: Djuric, Olivera, Giorgi Rossi, Paolo, Ivanciu, Elena Camelia, Cardellicchio, Salvatore, Cresci, Chiara, Carozzi, Laura, Pistelli, Francesco, Bessi, Valentina, Gai, Patrizia, Galli, Valentina, Lavacchini, Giacomo, Bricci, Claudia, Gorini, Giuseppe, Bosi, Sandra, Paci, Eugenio

Source: In Preventive Medicine Reports October 2023 35

Sex influences clinical phenotype in valosin-containing protein mutations: A case family report and systematic literature review

Authors: Leccese, Deborah, Rodolico, Gabriele Rosario, Sperti, Martina, Cassandrini, Denise, Bartolini, Marco, Ingannato, Assunta, Nacmias, Benedetta, Bracco, Laura, Malandrini, Alessandro, Santorelli, Filippo Maria, Bessi, Valentina, Matà, Sabrina

Source: In Clinical Neurology and Neurosurgery September 2023 232

Comparing two picture naming tasks in primary progressive aphasia: Insights from behavioural and neural results

Authors: Polito, Cristina, Conca, Francesca, Santi, Gaia C., Esposito, Valentina, Caminiti, Silvia P., Boccalini, Cecilia, Berti, Valentina, Morinelli, Carmen, Mazzeo, Salvatore, Marcone, Alessandra, Iannaccone, Sandro, Bessi, Valentina, Sorbi, Sandro, Perani, Daniela, Cappa, Stefano F., Catricalà, Eleonora

Source: In Cortex September 2023 166:1-18

Prodromal language impairment in genetic frontotemporal dementia within the GENFI cohort

Authors: Nelson, Annabel, Thomas, David L., Todd, Emily, Benotmane, Hanya, Nicholas, Jennifer, Shafei, Rachelle, Timberlake, Carolyn, Cope, Thomas, Rittman, Timothy, Benussi, Alberto, Premi, Enrico, Gasparotti, Roberto, Archetti, Silvana, Gazzina, Stefano, Cantoni, Valentina, Arighi, Andrea, Fenoglio, Chiara, Scarpini, Elio, Fumagalli, Giorgio, Borracci, Vittoria, Rossi, Giacomina, Giaccone, Giorgio, Di Fede, Giuseppe, Caroppo, Paola, Prioni, Sara, Redaelli, Veronica, Tang-Wai, David, Rogaeva, Ekaterina, Castelo-Branco, Miguel, Freedman, Morris, Keren, Ron, Black, Sandra, Mitchell, Sara, Shoesmith, Christen, Bartha, Robart, Rademakers, Rosa, Poos, Jackie, Papma, Janne M., Giannini, Lucia, van Minkelen, Rick, Pijnenburg, Yolande, Nacmias, Benedetta, Ferrari, Camilla, Polito, Cristina, Lombardi, Gemma, Bessi, Valentina, Veldsman, Michele, Andersson, Christin, Thonberg, Hakan, Öijerstedt, Linn, Jelic, Vesna, Thompson, Paul, Langheinrich, Tobias, Lladó, Albert, Antonell, Anna, Olives, Jaume, Balasa, Mircea, Bargalló, Nuria, Borrego-Ecija, Sergi, Verdelho, Ana, Maruta, Carolina, Ferreira, Catarina B., Miltenberger, Gabriel, do Couto, Frederico Simões, Gabilondo, Alazne, Gorostidi, Ana, Villanua, Jorge, Cañada, Marta, Tainta, Mikel, Zulaica, Miren, Barandiaran, Myriam, Alves, Patricia, Bender, Benjamin, Wilke, Carlo, Graf, Lisa, Vogels, Annick, Vandenbulcke, Mathieu, Van Damme, Philip, Bruffaerts, Rose, Poesen, Koen, Rosa-Neto, Pedro, Gauthier, Serge, Camuzat, Agnès, Brice, Alexis, Bertrand, Anne, Funkiewiez, Aurélie, Rinaldi, Daisy, Saracino, Dario, Colliot, Olivier, Sayah, Sabrina, Prix, Catharina, Wlasich, Elisabeth, Wagemann, Olivia, Loosli, Sandra, Schönecker, Sonja, Hoegen, Tobias, Lombardi, Jolina, Anderl-Straub, Sarah, Rollin, Adeline, Kuchcinski, Gregory, Bertoux, Maxime, Lebouvier, Thibaud, Deramecourt, Vincent, Santiago, Beatriz, Duro, Diana, Leitão, Maria João, Almeida, Maria Rosario, Tábuas-Pereira, Miguel, Afonso, Sónia, Samra, Kiran, MacDougall, Amy M., Bouzigues, Arabella, Bocchetta, Martina, Cash, David M., Greaves, Caroline V., Convery, Rhian S., van Swieten, John C., Jiskoot, Lize, Seelaar, Harro, Moreno, Fermin, Sanchez-Valle, Raquel, Laforce, Robert, Graff, Caroline, Masellis, Mario, Tartaglia, Maria Carmela, Rowe, James B., Borroni, Barbara, Finger, Elizabeth, Synofzik, Matthis, Galimberti, Daniela, Vandenberghe, Rik, de Mendonça, Alexandre, Butler, Chris R., Gerhard, Alex, Ducharme, Simon, Le Ber, Isabelle, Tiraboschi, Pietro, Santana, Isabel, Pasquier, Florence, Levin, Johannes, Otto, Markus, Sorbi, Sandro, Rohrer, Jonathan D., Russell, Lucy L.

Source: In Journal of the Neurological Sciences 15 August 2023 451

Early neurotransmitters changes in prodromal frontotemporal dementia: A GENFI study

Authors: Esteve, Aitana Sogorb, Heller, Carolin, Greaves, Caroline V., Zetterberg, Henrik, Swift, Imogen J., Samra, Kiran, Shafei, Rachelle, Timberlake, Carolyn, Cope, Thomas, Rittman, Timothy, Arighi, Andrea, Fenoglio, Chiara, Scarpini, Elio, Fumagalli, Giorgio, Borracci, Vittoria, Rossi, Giacomina, Giaccone, Giorgio, Di Fede, Giuseppe, Caroppo, Paola, Tiraboschi, Pietro, Prioni, Sara, Redaelli, Veronica, Tang-Wai, David, Rogaeva, Ekaterina, Castelo-Branco, Miguel, Freedman, Morris, Keren, Ron, Black, Sandra, Mitchell, Sara, Shoesmith, Christen, Bartha, Robart, Rademakers, Rosa, Poos, Jackie, Papma, Janne M., Giannini, Lucia, van Minkelen, Rick, Pijnenburg, Yolande, Nacmias, Benedetta, Ferrari, Camilla, Polito, Cristina, Lombardi, Gemma, Bessi, Valentina, Veldsman, Michele, Andersson, Christin, Thonberg, Hakan, Öijerstedt, Linn, Jelic, Vesna, Thompson, Paul, Langheinrich, Tobias, Lladó, Albert, Antonell, Anna, Olives, Jaume, Balasa, Mircea, Bargalló, Nuria, Borrego-Ecija, Sergi, Verdelho, Ana, Maruta, Carolina, Ferreira, Catarina B., Miltenberger, Gabriel, do Couto, Frederico Simões, Gabilondo, Alazne, Gorostidi, Ana, Villanua, Jorge, Cañada, Marta, Tainta, Mikel, Zulaica, Miren, Barandiaran, Myriam, Alves, Patricia, Bender, Benjamin, Wilke, Carlo, Graf, Lisa, Vogels, Annick, Vandenbulcke, Mathieu, Van Damme, Philip, Bruffaerts, Rose, Poesen, Koen, Rosa-Neto, Pedro, Gauthier, Serge, Camuzat, Agnès, Brice, Alexis, Bertrand, Anne, Funkiewiez, Aurélie, Rinaldi, Daisy, Saracino, Dario, Colliot, Olivier, Sayah, Sabrina, Prix, Catharina, Wlasich, Elisabeth, Wagemann, Olivia, Loosli, Sandra, Schönecker, Sonja, Hoegen, Tobias, Lombardi, Jolina, Anderl-Straub, Sarah, Rollin, Adeline, Kuchcinski, Gregory, Bertoux, Maxime, Lebouvier, Thibaud, Deramecourt, Vincent, Santiago, Beatriz, Duro, Diana, Leitão, Maria João, Almeida, Maria Rosario, Tábuas-Pereira, Miguel, Afonso, Sónia, Premi, Enrico, Pengo, Marta, Mattioli, Irene, Cantoni, Valentina, Dukart, Juergen, Gasparotti, Roberto, Buratti, Emanuele, Padovani, Alessandro, Bocchetta, Martina, Todd, Emily G., Bouzigues, Arabella, Cash, David M., Convery, Rhian S., Russell, Lucy L., Foster, Phoebe, Thomas, David L., van Swieten, John C., Jiskoot, Lize C., Seelaar, Harro, Galimberti, Daniela, Sanchez-Valle, Raquel, Laforce, Robert, Jr, Moreno, Fermin, Synofzik, Matthis, Graff, Caroline, Masellis, Mario, Tartaglia, Maria Carmela, Rowe, James B., Tsvetanov, Kamen A., Vandenberghe, Rik, Finger, Elizabeth, de Mendonça, Alexandre, Santana, Isabel, Butler, Chris R., Ducharme, Simon, Gerhard, Alexander, Levin, Johannes, Otto, Markus, Sorbi, Sandro, Le Ber, Isabelle, Pasquier, Florence, Rohrer, Jonathan D., Borroni, Barbara

Source: In Neurobiology of Disease April 2023 179

Degradation of EEG microstates patterns in subjective cognitive decline and mild cognitive impairment: Early biomarkers along the Alzheimer’s Disease continuum?

Authors: Lassi, Michael, Fabbiani, Carlo, Mazzeo, Salvatore, Burali, Rachele, Vergani, Alberto Arturo, Giacomucci, Giulia, Moschini, Valentina, Morinelli, Carmen, Emiliani, Filippo, Scarpino, Maenia, Bagnoli, Silvia, Ingannato, Assunta, Nacmias, Benedetta, Padiglioni, Sonia, Micera, Silvestro, Sorbi, Sandro, Grippo, Antonello, Bessi, Valentina, Mazzoni, Alberto

Source: In NeuroImage: Clinical 2023 38

Comprehensive qualitative characterization of linguistic performance profiles in primary progressive aphasia: a multivariate study with FDG-PET

Authors: Catricalà, Eleonora, Santi, Gaia C., Polito, Cristina, Conca, Francesca, Esposito, Valentina, Caminiti, Silvia P., Boccalini, Cecilia, Berti, Valentina, Bessi, Valentina, Marcone, Alessandra, Iannaccone, Sandro, Sorbi, Sandro, Perani, Daniela, Cappa, Stefano F.

Source: In Neurobiology of Aging December 2022 120:137-148

Loss of speech and functional impairment in Alzheimer's disease-related primary progressive aphasia: predictive factors of decline

Authors: Mazzeo, Salvatore, Polito, Cristina, Lassi, Michael, Bagnoli, Silvia, Mattei, Marta, Padiglioni, Sonia, Berti, Valentina, Lombardi, Gemma, Giacomucci, Giulia, De Cristofaro, Maria Teresa, Passeri, Alessandro, Ferrari, Camilla, Nacmias, Benedetta, Mazzoni, Alberto, Sorbi, Sandro, Bessi, Valentina

Source: In Neurobiology of Aging September 2022 117:59-70

Brain metabolic connectivity reconfiguration in the semantic variant of primary progressive aphasia

Authors: Boccalini, Cecilia, Carli, Giulia, Tondo, Giacomo, Polito, Cristina, Catricalà, Eleonora, Berti, Valentina, Bessi, Valentina, Sorbi, Sandro, Iannaccone, Sandro, Esposito, Valentina, Cappa, Stefano F., Perani, Daniela

Source: In Cortex September 2022 154:1-14

Personalized brain models link cognitive decline progression to underlying synaptic and connectivity degeneration.

Authors: Amato, Lorenzo Gaetano, Vergani, Alberto Arturo, Lassi, Michael, Carpaneto, Jacopo, Mazzeo, Salvatore, Moschini, Valentina, Burali, Rachele, Salvestrini, Giovanni, Fabbiani, Carlo, Giacomucci, Giulia, Galdo, Giulia, Morinelli, Carmen, Emiliani, Filippo, Scarpino, Maenia, Padiglioni, Sonia, Nacmias, Benedetta, Sorbi, Sandro, Grippo, Antonello, Bessi, Valentina, Mazzoni, Alberto

Source: Alzheimer's Research & Therapy; 4/5/2025, Vol. 17 Issue 1, p1-19, 19p

Subject Terms: MILD cognitive impairment, PHASE transitions, ALZHEIMER'S disease, COGNITION disorders, DIGITAL twin

Itel MMSE: a short phone screening test for cognitive decline. Italian Validation study by the SINdem Neuropsychology Working Group.

Authors: Quaranta, Davide, L'Abbate, Federica, Pelosi, Annalisa, Arighi, Andrea, Asoni, Gesuina, Bagattini, Chiara, Bessi, Valentina, Bonanni, Laura, Bortoletto, Marta, Bruni, Amalia Cecilia, Cagnin, Annachiara, Cappa, Stefano F., Giubilei, Franco, Guarino, Maria, Iavarone, Alessandro, Isella, Valeria, Luca, Antonina, Monastero, Roberto, Pellegrini, Francesca Ferrari, Perini, Marta

Source: Neurological Sciences; Apr2025, Vol. 46 Issue 4, p1617-1627, 11p

Subject Terms: ALZHEIMER'S disease, MILD cognitive impairment, COVID-19 pandemic, MEDICAL screening, MINI-Mental State Examination

Self-blaming as a barrier to lung cancer screening and smoking cessation programs in Italy. A qualitative study.

Authors: Ghirotto, Luca, Paci, Eugenio, Bricci, Claudia, Marini, Silvia, Bessi, Valentina, Díaz Crescitelli, Matías Eduardo, Rondini, Ermanno, Pistelli, Francesco, Gorini, Giuseppe, Bosi, Sandra, Giorgi Rossi, Paolo

Source: PLoS ONE; 3/5/2025, Vol. 20 Issue 3, p1-21, 21p

Subject Terms: SMOKING cessation, MEDICAL personnel, EARLY detection of cancer, LUNG cancer, JUDGMENT sampling

Intermediate alleles of HTT: A new pathway in longevity

Authors: Ingannato, Assunta, Bagnoli, Silvia, Bessi, Valentina, Ferrari, Camilla, Mazzeo, Salvatore, Sorbi, Sandro, Nacmias, Benedetta

Source: In Journal of the Neurological Sciences 15 July 2022 438

Unravelling neural correlates of empathy deficits in Subjective Cognitive Decline, Mild Cognitive Impairment and Alzheimer’s Disease

Authors: Giacomucci, Giulia, Galdo, Giulia, Polito, Cristina, Berti, Valentina, Padiglioni, Sonia, Mazzeo, Salvatore, Chiaro, Eleonora, De Cristofaro, Maria Teresa, Bagnoli, Silvia, Nacmias, Benedetta, Sorbi, Sandro, Bessi, Valentina

Source: In Behavioural Brain Research 25 June 2022 428