Disruption of nucleotide biosynthesis reprograms mitochondrial metabolism to inhibit adipogenesis

Authors: Pinette, Julia A. ¹, Myers, Jacob W. ¹, Park, Woo Yong ¹, Bryant, Heather G. ¹, Eddie, Alex M. ¹, Wilson, Genesis A. ¹, Montufar, Claudia ¹, Shaikh, Zayedali ¹, Vue, Zer ¹, Nunn, Elizabeth R. ¹, Bessho, Ryoichi ², Cottam, Matthew A. ³, Haase, Volker H. ^{1, 2, 4}, Hinton, Antentor O. ¹, Spinelli, Jessica B. ⁵, Cartailler, Jean-Philippe ³, Zaganjor, Elma ^{1, 6, 7, ∗}

Source: In Journal of Lipid Research October 2024 65(10)

A case of insulinoma diagnosed postpartum with hypoglycemic symptoms that were masked during pregnancy

Authors: Abe, Tomoe, Takeda, Yasutaka, Takiyama, Takao, Sasaki, Ayaka, Bessho, Ryoichi, Sato, Mao, Kitsunai, Hiroya, Sakagami, Hidemitsu, Abiko, Atsuko, Imai, Koji, Yuzawa, Sayaka, Tanino, Mishie, Takiyama, Yumi

Source: Clinical case reports. 9(4):1991-1998

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121118074.0x000001&indx=1&recIds=ETOCvdc_100121118074.0x000001

Efficacy of Alogliptin/Metformin Fixed-Dose Combination Tablets and Vildagliptin/Metformin Fixed-Dose Combination Tablets on Glycemic Control in Real-World Clinical Practice for the Patients with Type 2 Diabetes: A Multicenter, Open-Label, Randomized, Parallel Group, Comparative Trial

Authors: Abe, Tomoe, Takeda, Yasutaka, Sakuma, Ichiro, Okada, Mizuho, Kurigaki, Ayaka, Bessho, Ryoichi, Sato, Mao, Kitsunai, Hiroya, Takiyama, Yumi, Sakurai, Masaru

Source: Metabolic Syndrome & Related Disorders; Nov2024, Vol. 22 Issue 9, p651-660, 10p

Increment of plasma glucose by exogenous glucagon is associated with present and future renal function in type 2 diabetes:a retrospective study from glucagon stimulation test

Authors: Takeda, Yasutaka, Fujita, Yukihiro, Bessho, Ryoichi, Sato, Mao, Abe, Tomoe, Yanagimachi, Tsuyoshi, Sakagami, Hidemitsu, Abiko, Atsuko, Takiyama, Yumi, Ota, Tsuguhito, Haneda, Masakazu

Source: BMC endocrine disorders. 19(1):1-7

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190432998.0x000001&indx=1&recIds=ETOCvdc_100190432998.0x000001

Hypoxia-inducible factor-1α is the therapeutic target of the SGLT2 inhibitor for diabetic nephropathy

Authors: Bessho, Ryoichi, Takiyama, Yumi, Takiyama, Takao, Kitsunai, Hiroya, Takeda, Yasutaka, Sakagami, Hidemitsu, Ota, Tsuguhito

Source: Scientific reports. 9(1):1-12

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190851318.0x000001&indx=1&recIds=ETOCvdc_100190851318.0x000001

Establishment of novel specific assay for short‐form glucose‐dependent insulinotropic polypeptide and evaluation of its secretion in nondiabetic subjects

Authors: Takeda, Yasutaka, Fujita, Yukihiro, Yanagimachi, Tsuyoshi, Maruyama, Nobuhiro, Bessho, Ryoichi, Sakagami, Hidemitsu, Honjo, Jun, Yokoyama, Hiroki, Haneda, Masakazu

Source: Physiological reports. 8(11)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107620728.0x000001&indx=1&recIds=ETOCvdc_100107620728.0x000001

A maternal high-fat diet induces fetal origins of NASH-HCC in mice.

Authors: Takiyama, Takao, Sera, Toshihiro, Nakamura, Masanori, Hoshino, Masato, Uesugi, Kentaro, Horike, Shin-ichi, Meguro-Horike, Makiko, Bessho, Ryoichi, Takiyama, Yuri, Kitsunai, Hiroya, Takeda, Yasutaka, Sawamoto, Kazuki, Yagi, Naoto, Nishikawa, Yuji, Takiyama, Yumi

Source: Scientific Reports; 7/30/2022, Vol. 12 Issue 1, p1-24, 24p

Subject Terms: HIGH-fat diet, FETAL anoxia, REACTIVE oxygen species, NON-alcoholic fatty liver disease, UMBILICAL veins

Alternative Oxidase Expression Restores Kidney Progenitor Differentiation in Mice with Mitochondrial Complex lll Disruption

Authors: Bessho, Ryoichi, Kobayashi, Hanako, Haase, Volker H.

Source: Journal of the American Society of Nephrology; October 2024, Vol. 35 Issue: 10, Number 10 Supplement 10

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

391-P: The Nrf2 Activator Increases TFAM and Suppresses STING in Human Renal Proximal Tubular Cells.

Authors: BESSHO, RYOICHI¹ (AUTHOR), TAKIYAMA, TAKAO¹ (AUTHOR), PROMSUWAN, SURATSAWADEE¹ (AUTHOR), KITSUNAI, HIROYA¹ (AUTHOR), SAWAMOTO, KAZUKI¹ (AUTHOR), TAKEDA, YASUTAKA¹ (AUTHOR), TAKIYAMA, YUMI¹ (AUTHOR)

Source: Diabetes. 2021 Supplement 1, Vol. 70, pN.PAG-N.PAG. 1p.

1171-P: HORMAD1, a Novel Hypoxia-Inducible Factor-1 Target, Is Upregulated in Maternal Overnutrition-Induced Nonalcoholic Steatohepatitis (NASH)/Hepatocellular Carcinoma.

Authors: TAKIYAMA, TAKAO¹ (AUTHOR), BESSHO, RYOICHI¹ (AUTHOR), KITSUNAI, HIROYA¹ (AUTHOR), TAKEDA, YASUTAKA¹ (AUTHOR), SAKAGAMI, HIDEMITSU¹ (AUTHOR), SERA, TOSHIHIRO¹ (AUTHOR), NAKAMURA, MASANORI¹ (AUTHOR), HORIKE, SHIN-ICHI¹ (AUTHOR), NISHIKAWA, YUJI¹ (AUTHOR), TAKIYAMA, YUMI¹ (AUTHOR)

Source: Diabetes. 2021 Supplement 1, Vol. 70, pN.PAG-N.PAG. 1p.

1845-P: Maternal Overnutrition Causes DNA Alkylation in Fetal Liver, Suppresses FasL, and Upregulates HIF-1 Signaling Pathway in Neonatal Liver in Nonalcoholic Steatohepatitis (NASH)-Based Hepatocellular Carcinoma in Offspring.

Authors: TAKIYAMA, TAKAO¹ (AUTHOR), BESSHO, RYOICHI¹ (AUTHOR), SAWAMOTO, KAZUKI¹ (AUTHOR), TAKIYAMA, YUMI¹ (AUTHOR)

Source: Diabetes. 2020 Supplement, Vol. 69, pN.PAG-N.PAG. 1p.

492-P: A Novel Renoprotective Target of SGLT2 Inhibitor: HIF-1α Inhibition and AMPK Activation in Renal Proximal Tubular Epithelial Cells.

Authors: BESSHO, RYOICHI¹ (AUTHOR), TAKIYAMA, YUMI¹ (AUTHOR), TAKIYAMA, TAKAO¹ (AUTHOR), OTA, TSUGUHITO¹ (AUTHOR)

Source: Diabetes. 2019 Supplement, Vol. 68, pN.PAG-N.PAG. 1p.

493-P: Synchrotron Radiation Micro-CT Reveals Glomerular Loss without Glomerular or Renal Hypertrophy in Streptozotocin-Induced Type 1 Diabetic Mice.

Authors: TAKIYAMA, YUMI, SERA, TOSHIHIRO, NAKAMURA, MASANORI, BESSHO, RYOICHI, TAKIYAMA, TAKAO, OTA, TSUGUHITO, HANEDA, MASAKAZU

Source: Diabetes; 2019 Supplement, Vol. 68, pN.PAG-N.PAG, 1p

1948-P: Secretion of the Short-Form Gastric Inhibitory Polypeptide in Nondiabetic and Diabetic Subjects.

Authors: TAKEDA, YASUTAKA, FUJITA, YUKIHIRO, YANAGIMACHI, TSUYOSHI, MARUYAMA, NOBUHIRO, BESSHO, RYOICHI, SAKAGAMI, HIDEMITSU, HANEDA, MASAKAZU, OTA, TSUGUHITO

Source: Diabetes; 2019 Supplement, Vol. 68, pN.PAG-N.PAG, 1p

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.