Epigenome-wide association studies identify novel DNA methylation sites associated with PTSD: a meta-analysis of 23 military and civilian cohorts

Authors: Seyma Katrinli, Agaz H. Wani, Adam X. Maihofer, Andrew Ratanatharathorn, Nikolaos P. Daskalakis, Janitza Montalvo-Ortiz, Diana L. Núñez-Ríos, Anthony S. Zannas, Xiang Zhao, Allison E. Aiello, Allison E. Ashley-Koch, Diana Avetyan, Dewleen G. Baker, Jean C. Beckham, Marco P. Boks, Leslie A. Brick, Evelyn Bromet, Frances A. Champagne, Chia-Yen Chen, Shareefa Dalvie, Michelle F. Dennis, Segun Fatumo, Catherine Fortier, Sandro Galea, Melanie E. Garrett, Elbert Geuze, Gerald Grant, Michael A. Hauser, Jasmeet P. Hayes, Sian M. J. Hemmings, Bertrand Russel Huber, Aarti Jajoo, Stefan Jansen, Ronald C. Kessler, Nathan A. Kimbrel, Anthony P. King, Joel E. Kleinman, Nastassja Koen, Karestan C. Koenen, Pei-Fen Kuan, Israel Liberzon, Sarah D. Linnstaedt, Adriana Lori, Benjamin J. Luft, Jurjen J. Luykx, Christine E. Marx, Samuel A. McLean, Divya Mehta, William Milberg, Mark W. Miller, Mary S. Mufford, Clarisse Musanabaganwa, Jean Mutabaruka, Leon Mutesa, Charles B. Nemeroff, Nicole R. Nugent, Holly K. Orcutt, Xue-Jun Qin, Sheila A. M. Rauch, Kerry J. Ressler, Victoria B. Risbrough, Eugène Rutembesa, Bart P. F. Rutten, Soraya Seedat, Dan J. Stein, Murray B. Stein, Sylvanus Toikumo, Robert J. Ursano, Annette Uwineza, Mieke H. Verfaellie, Eric Vermetten, Christiaan H. Vinkers, Erin B. Ware, Derek E. Wildman, Erika J. Wolf, Ross McD Young, Ying Zhao, Leigh L. van den Heuvel, PGC-PTSD Epigenetics Workgroup, PsychENCODE PTSD Brainomics Project, Traumatic Stress Brain Research Group, Monica Uddin, Caroline M. Nievergelt, Alicia K. Smith, Mark W. Logue

Source: Genome Medicine, Vol 16, Iss 1, Pp 1-17 (2024)

Subject Terms: PTSD, Trauma, DNA methylation, Postmortem brain, GWAS, Gene expression, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1756-994X

Access URL: https://doaj.org/article/e7c75d3d1d50416e99e94207e5bfc3e1