Regional specialization of macrophages along the gastrointestinal tract

Authors: Berthold, Dorothée L., Jones, Kelsey D.J., Udalova, Irina A.

Source: In Trends in Immunology September 2021 42(9):795-806

Intestinal epithelial NAIP/NLRC4 restricts systemic dissemination of the adapted pathogen Salmonella Typhimurium due to site-specific bacterial PAMP expression

Authors: Hausmann, Annika, Böck, Desirée, Geiser, Petra, Berthold, Dorothée L., Fattinger, Stefan A., Furter, Markus, Bouman, Judith A., Barthel-Scherrer, Manja, Lang, Crispin M., Bakkeren, Erik, Kolinko, Isabel, Diard, Médéric, Bumann, Dirk, Slack, Emma, Regoes, Roland R., Pilhofer, Martin, Sellin, Mikael E., Hardt, Wolf-Dietrich

Source: In Mucosal Immunology 1 May 2020 13(3):530-544

Escherichia coli limits Salmonella Typhimurium infections after diet shifts and fat-mediated microbiota perturbation in mice

Authors: Wotzka, Sandra Y., Kreuzer, Markus, Maier, Lisa, Arnoldini, Markus, Nguyen, Bidong D., Brachmann, Alexander O., Berthold, Dorothée L., Zünd, Mirjam, Hausmann, Annika, Bakkeren, Erik, Hoces, Daniel, Gül, Ersin, Beutler, Markus, Dolowschiak, Tamas, Zimmermann, Michael, Fuhrer, Tobias, Moor, Kathrin, Sauer, Uwe, Typas, Athanasios, Piel, Jörn, Diard, Médéric, Macpherson, Andrew J., Stecher, Bärbel, Sunagawa, Shinichi, Slack, Emma, Hardt, Wolf-Dietrich

Source: Nature microbiology. 4(12):2164-2174

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130017813.0x000001&indx=1&recIds=ETOCvdc_100130017813.0x000001

Macrophages in the synovial lining niche initiate neutrophil recruitment and articular inflammation

Authors: Zec, Kristina, Schonfeldova, Barbora, Ai, Zhichao, Van Grinsven, Erinke, Pirgova, Gabriela, Eames, Hayley L., Berthold, Dorothée L., Attar, Moustafa, Compeer, Ewoud B., Arnon, Tal I.

Source: Journal of experimental medicine. 220(8):e20220595-e20220595

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN633231047&indx=1&recIds=ETOCRN633231047

Defactinib inhibits PYK2 phosphorylation of IRF5 and reduces intestinal inflammation.

Authors: Ryzhakov, Grigory, Almuttaqi, Hannah, Corbin, Alastair L., Berthold, Dorothée L., Khoyratty, Tariq, Eames, Hayley L., Bullers, Samuel, Pearson, Claire, Ai, Zhichao, Zec, Kristina, Bonham, Sarah, Fischer, Roman, Jostins-Dean, Luke, Travis, Simon P. L., Kessler, Benedikt M., Udalova, Irina A.

Source: Nature Communications; 11/18/2021, Vol. 12 Issue 1, p1-15, 15p

Subject Terms: INTESTINES, INFLAMMATORY bowel diseases, PHOSPHORYLATION, ULCERATIVE colitis, LABORATORY mice, INFLAMMATION

Neutrophilia, lymphopenia and myeloid dysfunction: a living review of the quantitative changes to innate and adaptive immune cells which define COVID-19 pathology.

Authors: Codd, Amy S, Hanna, Stephanie J, Compeer, Ewoud B, Richter, Felix C, Pring, Eleanor J, Gea-Mallorquí, Ester, Borsa, Mariana, Moon, Owen R, Scourfield, D Oliver, Oxford-Cardiff COVID-19 Literature Consortium, Ahern, David J, Almuttaqi, Hannah, Alonzi, Dominic S, Alrubayyi, Aljawharah, Alsaleh, Ghada, Bart, Valentina M T, Batchelor, Vicky, Bayliss, Rebecca, Berthold, Dorothée L, Bezbradica, Jelena S

Source: Oxford Open Immunology; 2021, Vol. 2 Issue 1, p1-13, 13p

Subject Terms: SARS-CoV-2, COVID-19, LYMPHOPENIA

The role and uses of antibodies in COVID-19 infections: a living review.

Authors: Scourfield, D Oliver, Reed, Sophie G, Quastel, Max, Alderson, Jennifer, Bart, Valentina M T, Teijeira Crespo, Alicia, Jones, Ruth, Pring, Ellie, Richter, Felix Clemens, The Oxford-Cardiff COVID-19 Literature Consortium, Ahern, David J, Almuttaqi, Hannah, Alonzi, Dominic S, Alrubayyi, Aljawharah, Alsaleh, Ghada, Batchelor, Vicky, Bayliss, Rebecca, Berthold, Dorothée L, Bezbradica, Jelena S, Bharuchq, Tehmina

Source: Oxford Open Immunology; 2021, Vol. 2 Issue 1, p1-13, 13p

Subject Terms: COVID-19, IMMUNOGLOBULINS, CONVALESCENT plasma, INFECTION control

Mucosal immune responses in COVID19 - a living review.

Authors: Pearson, Claire F, Jeffery, Rebecca, The Oxford-Cardiff COVID-19 Literature Consortium, Ahern, David J, Almuttaqi, Hannah, Alonzi, Dominic S, Alrubayyi, Aljawharah, Alsaleh, Ghada, Bart, Valentina M T, Batchelor, Vicky, Bayliss, Rebecca, Berthold, Dorothée L, Bezbradica, Jelena S, Bharuchq, Tehmina, Borrmann, Helene, Borsa, Mariana, Borst, Rowie, Brun, Juliane, Burnell, Stephanie, Capitani, Lorenzo

Source: Oxford Open Immunology; 2021, Vol. 2 Issue 1, p1-6, 6p

Subject Terms: IMMUNE response, MUCOUS membranes, COVID-19, GASTROINTESTINAL system, INFECTION

IRF5 guides monocytes toward an inflammatory CD11c⁺ macrophage phenotype and promotes intestinal inflammation.

Authors: Corbin, Alastair L., Gomez-Vazquez, Maria, Berthold, Dorothée L., Attar, Moustafa, Arnold, Isabelle C., Powrie, Fiona M., Sansom, Stephen N., Udalova, Irina A.

Source: Science Immunology; 2020, Vol. 5 Issue 47, p1-15, 15p

Intestinal epithelial NAIP/NLRC4 restricts systemic dissemination of the adapted pathogen SalmonellaTyphimurium due to site-specific bacterial PAMP expression

Authors: Hausmann, Annika, Böck, Desirée, Geiser, Petra, Berthold, Dorothée L., Fattinger, Stefan A., Furter, Markus, Bouman, Judith A., Barthel-Scherrer, Manja, Lang, Crispin M., Bakkeren, Erik, Kolinko, Isabel, Diard, Médéric, Bumann, Dirk, Slack, Emma, Regoes, Roland R., Pilhofer, Martin, Sellin, Mikael E., Hardt, Wolf-Dietrich

Source: Mucosal Immunology; May 2020, Vol. 13 Issue: 3 p530-544, 15p

Transient IgA, steady IgG?

Authors: Berthold, Dorothée L., Wormald, Catherine

Source: Nature Reviews Immunology; August 2020, Vol. 20 Issue: 8 p462-462, 1p

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