A transcriptomic pan-cancer signature for survival prognostication and prediction of immunotherapy response based on endothelial senescence

Authors: Zhengquan Wu, Bernd Uhl, Olivier Gires, Christoph A. Reichel

Source: Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-19 (2023)

Subject Terms: Endothelial cell senescence, Pan-cancer analysis, Immunotherapy, Prognosis, scRNA-seq, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1423-0127

Access URL: https://doaj.org/article/67bea446d8134c2a972758860be7ad30

Author Correction: Vascular surveillance by haptotactic blood platelets in inflammation and infection

Authors: Leo Nicolai, Karin Schiefelbein, Silvia Lipsky, Alexander Leunig, Marie Hoffknecht, Kami Pekayvaz, Ben Raude, Charlotte Marx, Andreas Ehrlich, Joachim Pircher, Zhe Zhang, Inas Saleh, Anna-Kristina Marel, Achim Löf, Tobias Petzold, Michael Lorenz, Konstantin Stark, Robert Pick, Gerhild Rosenberger, Ludwig Weckbach, Bernd Uhl, Sheng Xia, Christoph Andreas Reichel, Barbara Walzog, Christian Schulz, Vanessa Zheden, Markus Bender, Rong Li, Steffen Massberg, Florian Gaertner

Source: Nature Communications, Vol 13, Iss 1, Pp 1-4 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/ed292487695f4934991736364329901e

A novel OSA-related model of intermittent hypoxia in endothelial cells under flow reveals pronounced inflammatory pathway activation

Authors: Martin B. Müller, Clemens Stihl, Annika Schmid, Simon Hirschberger, Rea Mitsigiorgi, Martin Holzer, Martin Patscheider, Bernhard G. Weiss, Christoph Reichel, Max Hübner, Bernd Uhl

Source: Frontiers in Physiology, Vol 14 (2023)

Subject Terms: obstructive sleep apnea, intermittent hypoxia (IH), endothelial cell dysfunction, cell culture models, culture under flow, inflammation, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2023.1108966/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/4a9b5118629344b39a875644f6afa592

Vitronectin promotes immunothrombotic dysregulation in the venular microvasculature

Authors: Bernd Uhl, Florian Haring, Julia Slotta-Huspenina, Joshua Luft, Vera Schneewind, Jonas Hildinger, Zhengquan Wu, Katja Steiger, Bojan Smiljanov, Aarif M. N. Batcha, Oliver T. Keppler, Johannes C. Hellmuth, Tobias Lahmer, Konrad Stock, Bernhard G. Weiss, Martin Canis, Konstantin Stark, Thomas Bromberger, Markus Moser, Christian Schulz, Wilko Weichert, Gabriele Zuchtriegel, Christoph A. Reichel

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: immunothrombosis, platelets, neutrophils, microvasculature, systemic inflammation, SIRS, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1078005/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/ade407ee878a42518dbdd312efef54f7

uPA‐PAI‐1 heteromerization promotes breast cancer progression by attracting tumorigenic neutrophils

Authors: Bernd Uhl, Laura A Mittmann, Julian Dominik, Roman Hennel, Bojan Smiljanov, Florian Haring, Johanna B Schaubächer, Constanze Braun, Lena Padovan, Robert Pick, Martin Canis, Christian Schulz, Matthias Mack, Ewgenija Gutjahr, Peter Sinn, Jörg Heil, Katja Steiger, Sandip M Kanse, Wilko Weichert, Markus Sperandio, Kirsten Lauber, Fritz Krombach, Christoph A Reichel

Source: EMBO Molecular Medicine, Vol 13, Iss 6, Pp 1-16 (2021)

Subject Terms: biomarker, breast cancer, fibrinolysis, innate immunity, neutrophils, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/4c70973c2a744ff8b94cdcdb9b282bf8

Vascular surveillance by haptotactic blood platelets in inflammation and infection

Authors: Leo Nicolai, Karin Schiefelbein, Silvia Lipsky, Alexander Leunig, Marie Hoffknecht, Kami Pekayvaz, Ben Raude, Charlotte Marx, Andreas Ehrlich, Joachim Pircher, Zhe Zhang, Inas Saleh, Anna-Kristina Marel, Achim Löf, Tobias Petzold, Michael Lorenz, Konstantin Stark, Robert Pick, Gerhild Rosenberger, Ludwig Weckbach, Bernd Uhl, Sheng Xia, Christoph Andreas Reichel, Barbara Walzog, Christian Schulz, Vanessa Zheden, Markus Bender, Rong Li, Steffen Massberg, Florian Gaertner

Source: Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/4823a6cec2a1460586e33e31ba7a0aef

A Novel Experimental Approach for In Vivo Analyses of the Salivary Gland Microvasculature

Authors: Bernd Uhl, Constanze Braun, Julian Dominik, Joshua Luft, Martin Canis, Christoph A. Reichel

Source: Frontiers in Immunology, Vol 11 (2021)

Subject Terms: salivary gland, in vivo imaging, microcirculation, leukocyte trafficking, microvascular permeability, inflammation, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2020.604470/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/e3ab47f0c6f34970bf648fc919f042fe

Extratubular Polymerized Uromodulin Induces Leukocyte Recruitment and Inflammation In Vivo

Authors: Roland Immler, Bärbel Lange-Sperandio, Tobias Steffen, Heike Beck, Ina Rohwedder, Jonas Roth, Matteo Napoli, Georg Hupel, Frederik Pfister, Bastian Popper, Bernd Uhl, Hanna Mannell, Christoph A. Reichel, Volker Vielhauer, Jürgen Scherberich, Markus Sperandio, Monika Pruenster

Source: Frontiers in Immunology, Vol 11 (2020)

Subject Terms: uromodulin, damage associated molecular pattern (DAMP), inflammation, leukocyte recruitment, kidney disease, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2020.588245/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/745309dbf1514ede9534274d726a3ede

Priming of Anti-tumor Immune Mechanisms by Radiotherapy Is Augmented by Inhibition of Heat Shock Protein 90

Authors: Anne Ernst, Roman Hennel, Julia Krombach, Heidi Kapfhammer, Nikko Brix, Gabriele Zuchtriegel, Bernd Uhl, Christoph A. Reichel, Benjamin Frey, Udo S. Gaipl, Nicolas Winssinger, Senji Shirasawa, Takehiko Sasazuki, Markus Sperandio, Claus Belka, Kirsten Lauber

Source: Frontiers in Oncology, Vol 10 (2020)

Subject Terms: HSP90 inhibition, radiotherapy, anti-tumor immunity, immune priming, colorectal cancer, cancer immunology, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fonc.2020.01668/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/9ff4f87e978c409a88587d16d172b09f

Vitronectin stabilizes intravascular adhesion of neutrophils by coordinating β2 integrin clustering

Authors: Gabriele Zuchtriegel, Bernd Uhl, Robert Pick, Michaela Ramsauer, Julian Dominik, Laura A. Mittmann, Martin Canis, Sandip Kanse, Markus Sperandio, Fritz Krombach, Christoph A. Reichel

Source: Haematologica, Vol 106, Iss 10 (2020)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/9821; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/8d9ad4479b9e45e684bcfe0a8b6d74ae

Platelets Guide Leukocytes to Their Sites of Extravasation.

Authors: Gabriele Zuchtriegel, Bernd Uhl, Daniel Puhr-Westerheide, Michaela Pörnbacher, Kirsten Lauber, Fritz Krombach, Christoph Andreas Reichel

Source: PLoS Biology, Vol 14, Iss 5, p e1002459 (2016)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4859536?pdf=render; https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

Access URL: https://doaj.org/article/f5795824501c4e4ea51d294bc8cf3df4

Plasmin inhibitors prevent leukocyte accumulation and remodeling events in the postischemic microvasculature.

Authors: Christoph A Reichel, Max Lerchenberger, Bernd Uhl, Markus Rehberg, Nina Berberich, Stefan Zahler, Matthias P Wymann, Fritz Krombach

Source: PLoS ONE, Vol 6, Iss 2, p e17229 (2011)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21364954/pdf/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/9f20a55c123c4dfeae4eefe5ebad8b90