Efficacy and safety of tezepelumab versus placebo in adults with moderate to very severe chronic obstructive pulmonary disease (COURSE): a randomised, placebo-controlled, phase 2a trial

Authors: Belle-Isle, Jasmin, Nadeau, Jerome, Killorn, William, Francoeur, Bruno, Millaire, Emilie, Pek, Bonavuth, Ferguson, Murdo, Maltais, Francois, Killian, Kieran, Mazza, Giuseppe, Melenka, Lyle, Walker, Brandie, Bergeron, Celine, FitzGerald, John, Weinreich, Ulla Møller, Bendstrup, Elisabeth, Porsbjerg, Celeste, Ulrik, Charlotte, Titlestad, Ingrid, Meyer, Christian, Hilberg, Ole, Couturaud, Francis, Andrejak, Claire, Bourdin, Arnaud, Devouassoux, Gilles, Pepin, Jean-Louis, Chanez, Pascal, Cavailles, Arnaud, Eich, Andreas, Ludwig-Sengpiel, Andrea, Watz, Henrik, Schultz, Thomas, Bar-Shai, Amir, Wand, Ori, Adir, Yochai, Berkman, Neville, Fink, Gershon, Shitrit, David, Izbicki, Gabriel, Raviv, Yael, Wielders, Pascal, Goosens, Martijn, Heller-Baan, Roxane, in't Veen, Johannes, Custers, Frank, Oh, Yeon-Mok, Lee, YongChul, Kim, Jaeyeol, Yoo, Kwang-Ha, Park, Jung-Won, Lee, Sang Haak, Ahn, Joong Hyun, Lee, Sook Young, Kim, Jin Woo, Lee, Kwan Ho, Caballero, Luis Mateos, Naval Sendra, Elsa, Ramos Barbón, David, Velasco Garrido, José Luis, Alcázar Navarrete, Bernardino, Saralaya, Dinesh, Crooks, Michael, Shah, Pallav, Chaudhuri, Rekha, de Soyza, Anthony, Nordstrom, Monica, Dwarakanath, Akshay, Weinstein, Steven, Pham, David, Mitchell, John, Spangenthal, Selwyn, Surdulescu, Sever, Denenberg, Michael, Alpizar, Sady, Maybee, David, Moriarty, Timothy, Fakih, Faisal, Beasley, Richard, Heuer, Marvin, Patel, Amit, Dorf, Jeffrey, Martinez, Rafael, Kureishy, Shahrukh, Klein, Ryan, Hewitt, Mitzie, Cole, Jeremy, Robinette, Emory, Cordasco, Edward, Garver, Robert, Criner, Gerard, Sciurba, Frank, Kerwin, Edward, Lucksinger, Gregg, Delgado, John, Russian, David, Chupp, Geoffrey, Singh, Dave ^a, Brightling, Christopher E ^b, Rabe, Klaus F ^{c, d, e}, Han, MeiLan K ^f, Christenson, Stephanie A ^g, Drummond, M Bradley ^h, Papi, Alberto ⁱ, Pavord, Ian D ^j, Molfino, Nestor A ^k, Almqvist, Gun ^l, Kotalik, Ales ^m, Hellqvist, Åsa ⁿ, Gołąbek, Monika ^o, Sindhwani, Navreet S ^p, Ponnarambil, Sandhia S ^{q, *}

Source: In The Lancet Respiratory Medicine January 2025 13(1):47-58

Impact of Dyspnea on Adults With Respiratory Symptoms Without a Defined Diagnosis

Authors: Bierbrier, Jared, Gerstein, Emily, Whitmore, George A., Vandemheen, Katherine L., Bergeron, Celine, Boulet, Louis-Philippe, Cote, Andreanne, Field, Stephen K., Penz, Erika, McIvor, R. Andrew, Lemière, Catherine, Gupta, Samir, Hernandez, Paul, Mayers, Irvin, Bhutani, Mohit, Lougheed, M. Diane, Licskai, Christopher J., Azher, Tanweer, Ezer, Nicole, Ainslie, Martha, Alvarez, Gonzalo G., Mulpuru, Sunita, Aaron, Shawn D.

Source: In Chest December 2024 166(6):1296-1308

Exploring Definitions and Predictors of Response to Biologics for Severe Asthma

Authors: Scelo, Ghislaine, Tran, Trung N., Le, Tham T., Fagerås, Malin, Dorscheid, Delbert, Busby, John, Al-Ahmad, Mona, Al-Lehebi, Riyad, Altraja, Alan, Beastall, Aaron, Bergeron, Celine, Bjermer, Leif, Bjerrum, Anne S., Cano-Rosales, Diana Jimena, Canonica, Giorgio Walter, Carter, Victoria, Charriot, Jeremy, Christoff, George C., Cosio, Borja G., Denton, Eve, Fernandez-Sanchez, Maria Jose, Fonseca, João A., Gibson, Peter G., Goh, Celine, Heaney, Liam G., Heffler, Enrico, Hew, Mark, Iwanaga, Takashi, Katial, Rohit, Koh, Mariko S., Kuna, Piotr, Larenas-Linnemann, Désirée, Lehtimäki, Lauri, Mahboub, Bassam, Martin, Neil, Matsumoto, Hisako, Menzies-Gow, Andrew N., Papadopoulos, Nikolaos G., Patel, Pujan, Perez-De-Llano, Luis, Peters, Matthew, Pfeffer, Paul E., Popov, Todor A., Porsbjerg, Celeste M., Rhee, Chin K., Sadatsafavi, Mohsen, Taillé, Camille, Torres-Duque, Carlos A., Tsai, Ming-Ju, Ulrik, Charlotte S., Upham, John W., von Bülow, Anna, Wang, Eileen, Wechsler, Michael E., Price, David B.

Source: In The Journal of Allergy and Clinical Immunology: In Practice September 2024 12(9):2347-2361

International Variation in Severe Exacerbation Rates in Patients With Severe Asthma

Authors: Lee, Tae Yoon, Price, David, Yadav, Chandra Prakash, Roy, Rupsa, Lim, Laura Huey Mien, Wang, Eileen, Wechsler, Michael E., Jackson, David J., Busby, John, Heaney, Liam G., Pfeffer, Paul E., Mahboub, Bassam, Perng (Steve), Diahn-Warng, Cosio, Borja G., Perez-de-Llano, Luis, Al-Lehebi, Riyad, Larenas-Linnemann, Désirée, Al-Ahmad, Mona, Rhee, Chin Kook, Iwanaga, Takashi, Heffler, Enrico, Canonica, Giorgio Walter, Costello, Richard, Papadopoulos, Nikolaos G., Papaioannou, Andriana I., Porsbjerg, Celeste M., Torres-Duque, Carlos A., Christoff, George C., Popov, Todor A., Hew, Mark, Peters, Matthew, Gibson, Peter G., Maspero, Jorge, Bergeron, Celine, Cerda, Saraid, Contreras-Contreras, Elvia Angelica, Chen, Wenjia, Sadatsafavi, Mohsen

Source: In Chest July 2024 166(1):28-38

Analysis of comorbidities and multimorbidity in adult patients in the International Severe Asthma Registry

Authors: Scelo, Ghislaine ^*, Torres-Duque, Carlos A., Maspero, Jorge, Tran, Trung N., Murray, Ruth, Martin, Neil, Menzies-Gow, Andrew N., Hew, Mark, Peters, Matthew J., Gibson, Peter G., Christoff, George C., Popov, Todor A., Côté, Andréanne, Bergeron, Celine, Dorscheid, Delbert, FitzGerald, J. Mark, Chapman, Kenneth R., Boulet, Louis Philippe, Bhutani, Mohit, Sadatsafavi, Mohsen, Jiménez-Maldonado, Libardo, Duran-Silva, Mauricio, Rodriguez, Bellanid, Celis-Preciado, Carlos Andres, Cano-Rosales, Diana Jimena, Solarte, Ivan, Fernandez-Sanchez, Maria Jose, Parada-Tovar, Patricia, von Bülow, Anna, Bjerrum, Anne Sofie, Ulrik, Charlotte S., Assing, Karin Dahl, Rasmussen, Linda Makowska, Hansen, Susanne, Altraja, Alan, Bourdin, Arnaud, Taille, Camille, Charriot, Jeremy, Roche, Nicolas, Papaioannou, Andriana I., Kostikas, Konstantinos, Papadopoulos, Nikolaos G., Salvi, Sundeep, Long, Deirdre, Mitchell, Patrick D., Costello, Richard, Sirena, Concetta, Cardini, Cristina, Heffler, Enrico, Puggioni, Francesca, Canonica, Giorgio Walter, Guida, Giuseppe, Iwanaga, Takashi, Al-Ahmad, Mona, Linnemann, Désirée Larenas, Garcia, Ulises, Kuna, Piotr, Fonseca, João A., Al-Lehebi, Riyad, Koh, Mariko Siyue, Rhee, Chin Kook, Cosio, Borja G., de Llano, Luis Perez, Perng (Steve), Diahn-Warng, Huang, Erick Wan-Chun, Wang, Hao-Chien, Tsai, Ming-Ju, Mahboub, Bassam, Salameh, Laila Ibraheem Jaber, Jackson, David, Busby, John, Heaney, Liam G., Pfeffer, Paul, Goddard, Amanda Grippen, Wang, Eileen, Hoyte, Flavia, Wechsler, Michael E., Chapman, Nicholas, Katial, Rohit, Carter, Victoria ^*, Bulathsinhala, Lakmini ^*, Eleangovan, Neva ^*, Ariti, Con ^*, Lyu, Juntao, Price, David B., Porsbjerg, Celeste

Source: In Annals of Allergy, Asthma & Immunology January 2024 132(1):42-53

Asthma patients' perspectives on telehealth in disease management: A focus group study

Authors: Chae, Yu seon Sarah, Tregobov, Noah, McMillan, Austin, Bergeron, Celine, Poureslami, Iraj

Source: In Health Care Transitions 2023 1

Disease burden in individuals with symptomatic undiagnosed asthma or COPD

Authors: Alhabeeb, Fatmah F., Whitmore, G.A., Vandemheen, Katherine L., FitzGerald, J. Mark, Bergeron, Celine, Lemière, Catherine, Boulet, Louis-Philippe, Field, Stephen K., Penz, Erika, McIvor, R. Andrew, Gupta, Samir, Mayers, Irvin, Bhutani, Mohit, Hernandez, Paul, Lougheed, Diane, Licskai, Christopher J., Azher, Tanweer, Cote, Andreanne, Ainslie, Martha, Fraser, Ian, Mahdavian, Masoud, Aaron, Shawn D.

Source: In Respiratory Medicine August-September 2022 200

Anticipating undiagnosed asthma in symptomatic adults with normal pre- and post-bronchodilator spirometry: a decision tool for bronchial challenge testing.

Authors: Shin, Sheojung, Whitmore, George Alex, Boulet, Louis-Philippe, Boulay, Marie-Ève, Côté, Andréanne, Bergeron, Céline, Lemière, Catherine, Lougheed, M. Diane, Vandemheen, Katherine L., Alvarez, Gonzalo G., Mulpuru, Sunita, Aaron, Shawn D.

Source: BMC Pulmonary Medicine; 12/9/2023, Vol. 23 Issue 1, p1-11, 11p

Subject Terms: SPIROMETRY, ASTHMA, COUGH, ASTHMATICS, WHEEZE, ADULTS, LUNG diseases

Fibroblast growth factor-2 is a sputum remodeling biomarker of severe asthma

Authors: Bissonnette, Élyse Y., Madore, Anne-Marie, Chakir, Jamila, Laviolette, Michel, Boulet, Louis-Philippe, Hamid, Qutayba, Bergeron, Céline, Maghni, Karim, Laprise, Catherine

Source: Journal of asthma. 51(2):119-126

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100103926404.0x000001&indx=1&recIds=ETOCvdc_100103926404.0x000001

Influence of cigarette smoke on the arginine pathway in asthmatic airways: Increased expression of arginase I

Authors: Bergeron, Céline, Boulet, Louis-Philippe, Page, Nathalie, Laviolette, Michel, Zimmermann, Nives, Rothenberg, Marc E., Hamid, Qutayba

Source: In The Journal of Allergy and Clinical Immunology 2007 119(2):391-397

Structural Changes in Airway Diseases: Characteristics, Mechanisms, Consequences, and Pharmacologic Modulation

Authors: Bergeron, Celine, Boulet, Louis-Philippe

Source: In Chest April 2006 129(4):1068-1087

Evidence of remodeling in peripheral airways of patients with mild to moderate asthma: Effect of hydrofluoroalkane-flunisolide

Authors: Bergeron, Celine, Hauber, Hans Peter, Gotfried, Mark, Newman, Kenneth, Dhanda, Rahul, Servi, Ronald J., Ludwig, Mara S., Hamid, Qutayba

Source: In The Journal of Allergy and Clinical Immunology 2005 116(5):983-989

Oral corticosteroids decrease eosinophil and CC chemokine expression but increase neutrophil, IL-8, and IFN-γ–inducible protein 10 expression in asthmatic airway mucosa

Authors: Fukakusa, Motonori, Bergeron, Celine, Tulic, Meri K., Fiset, Pierre-Olivier, Al Dewachi, Oday, Laviolette, Michel, Hamid, Qutayba, Chakir, Jamila

Source: In The Journal of Allergy and Clinical Immunology 2005 115(2):280-286

Lessons from lung transplantation: Cause for redefining the pathophysiology of pulmonary hypertension in gaucher disease

Authors: Goobie, Gillian C., Sirrs, Sandra M., Yee, John, English, John C., Bergeron, Celine, Nador, Roland, Swiston, John R., Mistry, Pramod K., Paquin, Wendy, Levy, Robert D.

Source: In Respiratory Medicine Case Reports 2019 28

Interleukin-4 Promotes Airway Remodeling in Asthma: Regulation of Procollagen I (α1) Gene by Interleukin-4

Authors: Bergeron, Céline, Pagé, Nathalie, Barbeau, Benoit, Chakir, Jamila

Source: In Chest March 2003 123(3) Supplement:424S-424S

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Increased glucocorticoid receptor–β expression, but not decreased histone deacetylase 2, in severe asthma

Authors: Bergeron, Celine, Fukakusa, Motoroni, Olivenstein, Ronald, Lemiere, Catherine, Shannon, Joanne, Ernst, Pierre, Martin, James G., Hamid, Qutayba

Source: In The Journal of Allergy and Clinical Immunology 2006 117(3):703-705

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Obstructive sleep apnea syndrome and inflammation

Authors: Bergeron, Celine, Kimoff, John, Hamid, Qutayba

Source: In The Journal of Allergy and Clinical Immunology 2005 116(6):1393-1396