Tetrahydropyridine LIMK inhibitors: Structure activity studies and biological characterization

Authors: Champiré, Anthony, Berabez, Rayan, Braka, Abdennour, Cosson, Aurélie, Corret, Justine, Girardin, Caroline, Serrano, Amandine, Aci-Sèche, Samia, Bonnet, Pascal, Josselin, Béatrice, Brindeau, Pierre, Ruchaud, Sandrine, Leguevel, Rémy, Chatterjee, Deep, Mathea, Sebastian, Knapp, Stefan, Brion, Régis, Verrecchia, Franck, Vallée, Béatrice, Plé, Karen, Bénédetti, Hélène, Routier, Sylvain

Source: In European Journal of Medicinal Chemistry 5 May 2024 271

LIM Kinases, Promising but Reluctant Therapeutic Targets: Chemistry and Preclinical Validation In Vivo.

Authors: Berabez, Rayan¹ (AUTHOR) rayan.berabez@univ-orleans.fr, Routier, Sylvain¹ (AUTHOR) sylvain.routier@univ-orleans.fr, Bénédetti, Hélène² (AUTHOR) helene.benedetti@cnrs.fr, Plé, Karen¹ (AUTHOR) karen.ple@univ-orleans.fr, Vallée, Béatrice² (AUTHOR) karen.ple@univ-orleans.fr

Source: Cells (2073-4409). Jul2022, Vol. 11 Issue 13, pN.PAG-N.PAG. 22p.

Subject Terms: *KINASES, *DRUG target, *SMALL molecules, *G proteins, *STRUCTURE-activity relationships, *ACTIN

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Hexafluoroisopropanol as the Acid Component in the Passerini Reaction: One-Pot Access to β‑Amino Alcohols.

Authors: Saya, Jordy M.¹ (AUTHOR), Berabez, Rayan¹ (AUTHOR), Broersen, Pim¹ (AUTHOR), Schuringa, Imme¹ (AUTHOR), Kruithof, Art¹ (AUTHOR), Orru, Romano V. A.¹ (AUTHOR), Ruijter, Eelco¹ (AUTHOR) e.ruijter@vu.nl

Source: Organic Letters. Jul2018, Vol. 20 Issue 13, p3988-3991. 4p.