Nucleosomes impede Cas9 access to DNA in vivo and in vitro

Authors: Max A Horlbeck, Lea B Witkowsky, Benjamin Guglielmi, Joseph M Replogle, Luke A Gilbert, Jacqueline E Villalta, Sharon E Torigoe, Robert Tjian, Jonathan S Weissman

Source: eLife, Vol 5 (2016)

Subject Terms: CRISPR/Cas, nucleosomes, chromatin, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/12677; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/0b04a6d7357c482dbd1342412af468f4