Mammary intraepithelial lymphocytes promote lactogenesis and offspring fitness

Authors: Corral, Dan ^{1, ∗}, Ansaldo, Eduard ¹, Delaleu, Jérémie ¹, Pichler, Andrea C. ², Kabat, Juraj ³, Oguz, Cihan ⁴, Teijeiro, Ana ¹, Yong, Daniel ¹, Abid, Mahnoor ¹, Rivera, Claudia A. ¹, Link, Verena M. ¹, Yang, Katharine ⁵, Chi, Liang ¹, Nie, Jia ⁶, Kamenyeva, Olena ³, Fan, Yiping ^{7, 8, 9}, Chan, Jerry Kok Yen ^{7, 8, 9}, Ginhoux, Florent ^{5, 10}, Bosselut, Rémy ⁶, Belkaid, Yasmine ^{1, 11, 12, ∗∗}

Source: In Cell 20 March 2025 188(6):1662-1680

CRISPR screens unveil nutrient-dependent lysosomal and mitochondrial nodes impacting intestinal tissue-resident memory CD8+ T cell formation

Authors: Raynor, Jana L., Collins, Nicholas, Shi, Hao, Guy, Cliff, Saravia, Jordy, Ah Lim, Seon, Chapman, Nicole M., Zhou, Peipei, Wang, Yan, Sun, Yu, Risch, Isabel, Hu, Haoran, KC, Anil, Sun, Renqiang, Shrestha, Sharad, Huang, Hongling, Connelly, Jon P., Pruett-Miller, Shondra M., Reina-Campos, Miguel, Goldrath, Ananda W., Belkaid, Yasmine, Chi, Hongbo

Source: In Immunity 12 November 2024 57(11):2597-2614

Translocating bacteria in SIV infection are not stochastic and preferentially express cytosine methyltransferases

Authors: Flynn, Jacob K., Ortiz, Alexandra M., Vujkovic-Cvijin, Ivan, Welles, Hugh C., Simpson, Jennifer, Castello Casta, Fabiola M., Yee, Debra S., Rahmberg, Andrew R., Brooks, Kelsie L., De Leon, Marlon, Knodel, Samantha, Birse, Kenzie, Noel-Romas, Laura, Deewan, Anshu, Belkaid, Yasmine, Burgener, Adam, Brenchley, Jason M.

Source: In Mucosal Immunology October 2024 17(5):1089-1101

A CTCF-binding site in the Mdm1-Il22-Ifng locus shapes cytokine expression profiles and plays a critical role in early Th1 cell fate specification

Authors: Liu, Chunhong ¹, Nagashima, Hiroyuki ², Fernando, Nilisha ¹, Bass, Victor ¹, Gopalakrishnan, Jaanam ¹, Signorella, Sadie ^{1, 2}, Montgomery, Will ¹, Lim, Ai Ing ³, Harrison, Oliver ³, Reich, Lauren ¹, Yao, Chen ², Sun, Hong-Wei ⁴, Brooks, Stephen R. ⁴, Jiang, Kan ⁴, Nagarajan, Vijayaraj ¹, Zhao, Yongbing ², Jung, Seolkyoung ², Philips, Rachael ², Mikami, Yohei ², Lareau, Caleb A. ⁵, Kanno, Yuka ², Jankovic, Dragana ⁶, Aryee, Martin J. ⁵, Pękowska, Aleksandra ⁷, Belkaid, Yasmine ³, O’Shea, John ², Shih, Han-Yu ^{1, 8, 9, ∗}

Source: In Immunity 14 May 2024 57(5):1005-1018

Transcription factor Tox2 is required for metabolic adaptation and tissue residency of ILC3 in the gut

Authors: Das, Arundhoti ¹, Martinez-Ruiz, Gustavo Ulises ^{1, 2, 3}, Bouladoux, Nicolas ⁴, Stacy, Apollo ^{4, 5}, Moraly, Josquin ⁶, Vega-Sendino, Maria ¹, Zhao, Yongge ¹, Lavaert, Marieke ¹, Ding, Yi ¹, Morales-Sanchez, Abigail ^{1, 3}, Harly, Christelle ^{7, 8}, Seedhom, Mina O. ⁹, Chari, Raj ¹⁰, Awasthi, Parirokh ¹¹, Ikeuchi, Tomoko ¹², Wang, Yueqiang ¹³, Zhu, Jinfang ¹⁴, Moutsopoulos, Niki M. ¹², Chen, WanJun ¹⁵, Yewdell, Jonathan W. ⁹, Shapiro, Virginia Smith ¹⁶, Ruiz, Sergio ¹, Taylor, Naomi ⁶, Belkaid, Yasmine ⁴, Bhandoola, Avinash ^{1, 17, ∗}

Source: In Immunity 14 May 2024 57(5):1019-1036

Immunometabolism at the crossroads of obesity and cancer—a Keystone Symposia report

Authors: Cable, Jennifer, Rathmell, Jeffrey C., Pearce, Erika L., Ho, Ping‐Chih, Haigis, Marcia C., Mamedov, Murad R., Wu, Meng‐Ju, Kaech, Susan M., Lynch, Lydia, Febbraio, Mark A., Bapat, Sagar P., Hong, Hanna S., Zou, Weiping, Belkaid, Yasmine, Sullivan, Zuri A., Keller, Andrea, Wculek, Stefanie K., Green, Douglas R., Postic, Catherine, Amit, Ido, Benitah, Salvador Aznar, Jones, Russell G., Reina‐Campos, Miguel, Torres, Santiago Valle, Beyaz, Semir, Brennan, Donal, O'Neill, Luke A. J., Perry, Rachel J., Brenner, Dirk

Source: Annals of the New York Academy of Sciences. 1523(1):38-50

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182491956.0x000001&indx=1&recIds=ETOCvdc_100182491956.0x000001

Immune checkpoint inhibitors unleash pathogenic immune responses against the microbiota

Authors: Hu, Zishuo Ian, Link, Verena M., Lima-Junior, Djalma S., Delaleu, Jérémie, Bouladoux, Nicolas, Han, Seong-Ji, Collins, Nicholas, Belkaid, Yasmine

Source: Proceedings of the National Academy of Sciences of the United States of America, 2022 Jun . 119(26), 1-10.

Access URL: https://www.jstor.org/stable/27152839

Immunity to the microbiota promotes sensory neuron regeneration

Authors: Enamorado, Michel, Kulalert, Warakorn, Han, Seong-Ji, Rao, Indira, Delaleu, Jérémie, Link, Verena M., Yong, Daniel, Smelkinson, Margery, Gil, Louis, Nakajima, Saeko, Linehan, Jonathan L., Bouladoux, Nicolas, Wlaschin, Josette, Kabat, Juraj, Kamenyeva, Olena, Deng, Liwen, Gribonika, Inta, Chesler, Alexander T., Chiu, Isaac M., Le Pichon, Claire E., Belkaid, Yasmine

Source: In Cell 2 February 2023 186(3):607-620

Experimental bacterial dysbiosis with consequent immune alterations increase intrarectal SIV acquisition susceptibility

Authors: Ortiz, Alexandra M., Baker, Phillip J., Langner, Charlotte A., Simpson, Jennifer, Stacy, Apollo, Flynn, Jacob K., Starke, Carly E., Vinton, Carol L., Fennessey, Christine M., Belkaid, Yasmine, Keele, Brandon F., Brenchley, Jason M.

Source: In Cell Reports 31 January 2023 42(1)

Control of immunity via nutritional interventions

Authors: Collins, Nicholas, Belkaid, Yasmine

Source: Immunity. 55(2):210-223

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100155195975.0x000001&indx=1&recIds=ETOCvdc_100155195975.0x000001

Long-term antibiotic exposure promotes mortality after systemic fungal infection by driving lymphocyte dysfunction and systemic escape of commensal bacteria

Authors: Drummond, Rebecca A. ^{1, 2, 9, ∗}, Desai, Jigar V. ^{1, 9}, Ricotta, Emily E. ¹, Swamydas, Muthulekha ¹, Deming, Clay ³, Conlan, Sean ³, Quinones, Mariam ⁴, Matei-Rascu, Veronika ², Sheriff, Lozan ², Lecky, David ², Lee, Chyi-Chia R. ⁵, Green, Nathaniel M. ¹, Collins, Nicholas ⁶, Zelazny, Adrian M. ⁷, Prevots, D. Rebecca ¹, Bending, David ², Withers, David ², Belkaid, Yasmine ^{6, 8}, Segre, Julia A. ³, Lionakis, Michail S. ^{1, 10, ∗∗}

Source: In Cell Host & Microbe 13 July 2022 30(7):1020-1033

Genetic variation in IL-4 activated tissue resident macrophages determines strain-specific synergistic responses to LPS epigenetically.

Authors: Zhao, Mingming, Jankovic, Dragana, Link, Verena M., Souza, Camila Oliveira Silva, Hornick, Katherine M., Oyesola, Oyebola, Belkaid, Yasmine, Lack, Justin, Loke, Png

Source: Nature Communications; 1/25/2025, Vol. 16 Issue 1, p1-20, 20p

Subject Terms: SUPER enhancers, LIFE sciences, BONE marrow, GENETIC variation, PERITONEUM

ILC precursors differentiate into metabolically distinct ILC1-like cells during Mycobacterium tuberculosis infection

Authors: Corral, Dan, Charton, Alison, Krauss, Maria Z., Blanquart, Eve, Levillain, Florence, Lefrançais, Emma, Sneperger, Tamara, Vahlas, Zoï, Girard, Jean-Philippe, Eberl, Gérard, Poquet, Yannick, Guéry, Jean-Charles, Argüello, Rafael J., Belkaid, Yasmine, Mayer-Barber, Katrin D., Hepworth, Matthew R., Neyrolles, Olivier, Hudrisier, Denis

Source: In Cell Reports 19 April 2022 39(3)

The neuropeptide VIP potentiates intestinal innate type 2 and type 3 immunity in response to feeding

Authors: Pascal, Maud, Kazakov, Alexander, Chevalier, Grégoire, Dubrule, Lola, Deyrat, Julie, Dupin, Alice, Saha, Soham, Jagot, Ferdinand, Sailor, Kurt, Dulauroy, Sophie, Moigneu, Carine, Belkaid, Yasmine, Lepousez, Gabriel, Lledo, Pierre-Marie, Wilhelm, Christoph, Eberl, Gérard

Source: In Mucosal Immunology April 2022 15(4):629-641

Immunity to commensal skin fungi promotes psoriasiform skin inflammation

Authors: Hurabielle, Charlotte, Link, Verena M., Bouladoux, Nicolas, Han, Seong-Ji, Merrill, Eric Dean, Lightfoot, Yaima L., Seto, Nickie, Bleck, Christopher K. E., Smelkinson, Margery, Harrison, Oliver J., Linehan, Jonathan L., Tamoutounour, Samira, Lionakis, Michail S., Kaplan, Mariana J., Nakajima, Saeko, Belkaid, Yasmine

Source: Proceedings of the National Academy of Sciences of the United States of America, 2020 Jul . 117(28), 16465-16474.

Access URL: https://www.jstor.org/stable/26935240

Environmental enteric dysfunction induces regulatory T cells that inhibit local CD4+ T cell responses and impair oral vaccine efficacy

Authors: Bhattacharjee, Amrita, Burr, Ansen H.P., Overacre-Delgoffe, Abigail E., Tometich, Justin T., Yang, Deyi, Huckestein, Brydie R., Linehan, Jonathan L., Spencer, Sean P., Hall, Jason A., Harrison, Oliver J., Morais da Fonseca, Denise, Norton, Elizabeth B., Belkaid, Yasmine, Hand, Timothy W.

Source: In Immunity 10 August 2021 54(8):1745-1757

Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota

Authors: Lima-Junior, Djalma S., Krishnamurthy, Siddharth R., Bouladoux, Nicolas, Collins, Nicholas, Han, Seong-Ji, Chen, Erin Y., Constantinides, Michael G., Link, Verena M., Lim, Ai Ing, Enamorado, Michel, Cataisson, Christophe, Gil, Louis, Rao, Indira, Farley, Taylor K., Koroleva, Galina, Attig, Jan, Yuspa, Stuart H., Fischbach, Michael A., Kassiotis, George, Belkaid, Yasmine

Source: In Cell 8 July 2021 184(14):3794-3811

Discovery and engineering of the antibody response to a prominent skin commensal

Authors: Bousbaine, Djenet, Bauman, Katherine D., Chen, Y. Erin, Lalgudi, Pranav V., Nguyen, Tam T. D., Swenson, Joyce M., Yu, Victor K., Tsang, Eunice, Conlan, Sean, Li, David B., Jbara, Amina, Zhao, Aishan, Naziripour, Arash, Veinbachs, Alessandra, Lee, Yu E., Phung, Jennie L., Dimas, Alex, Jain, Sunit, Meng, Xiandong, Pham, Thi Phuong Thao, McLaughlin, Martin I., Barkal, Layla J., Gribonika, Inta, Van Rompay, Koen K. A., Kong, Heidi H., Segre, Julia A., Belkaid, Yasmine, Barnes, Christopher O., Fischbach, Michael A.

Source: Nature; February 2025, Vol. 638 Issue: 8052 p1054-1064, 11p

Skin autonomous antibody production regulates host–microbiota interactions

Authors: Gribonika, Inta, Band, Victor I., Chi, Liang, Perez-Chaparro, Paula Juliana, Link, Verena M., Ansaldo, Eduard, Oguz, Cihan, Bousbaine, Djenet, Fischbach, Michael A., Belkaid, Yasmine

Source: Nature; February 2025, Vol. 638 Issue: 8052 p1043-1053, 11p

Murine model of colonization with fungal pathogen Candida auris to explore skin tropism, host risk factors and therapeutic strategies

Authors: Huang, Xin, Hurabielle, Charlotte, Drummond, Rebecca A., Bouladoux, Nicolas, Desai, Jigar V., Sim, Choon K., Belkaid, Yasmine, Lionakis, Michail S., Segre, Julia A.

Source: In Cell Host & Microbe 10 February 2021 29(2):210-221