FXR-ApoC2 pathway activates UCP1-mediated thermogenesis by promoting the browning of white adipose tissues

Authors: Kim, Sang Hee ^{1, ‡}, Park, Woo Yong ^{1, 2, ‡}, Kim, Beomsu ¹, Kim, Jin-Hyung ³, Song, Gahee ^{1, 2, 4}, Park, Ja Yeon ¹, Jiao, Wenjun ¹, Jung, Se Jin ¹, Ahn, Kwang Seok ^{1, 4}, Kwak, Hyun Jeong ⁵, Um, Jae-Young ^{1, 2, 4, ∗}

Source: In Journal of Biological Chemistry March 2025 301(3)

Regulation of UCP1 expression by PPARα and pemafibrate in human beige adipocytes

Authors: Batrow, Pierre-Louis ^a, Roux, Christian H. ^{a, b}, Gautier, Nadine ^a, Martin, Luc ^a, Sibille, Brigitte ^a, Guillou, Hervé ^c, Postic, Catherine ^d, Langin, Dominique ^{e, f, g}, Mothe-Satney, Isabelle ^a, Amri, Ez-Zoubir ^{a, ⁎}

Source: In Life Sciences 15 February 2025 363

Decoding temporal thermogenesis: coregulator selectivity and transcriptional control in brown and beige adipocytes

Authors: Yong Geun Jeon, Sun Won Kim, Jae Bum Kim

Source: Adipocyte, Vol 13, Iss 1 (2024)

Subject Terms: Thermogenesis, brown adipocyte, beige adipocyte, co-regulators, RNF20, Diseases of the endocrine glands. Clinical endocrinology, RC648-665, Cytology, QH573-671, Physiology, QP1-981

File Description: electronic resource

Relation: https://doaj.org/toc/2162-3945; https://doaj.org/toc/2162-397X

Access URL: https://doaj.org/article/888ba272eed148ed8150289f0ea7ffb7

Directly targeting PRDM16 in thermogenic adipose tissue to treat obesity and its related metabolic diseases

Authors: Liufeng Mao, Jinli Lu, Yunliang Hou, Tao Nie

Source: Frontiers in Endocrinology, Vol 15 (2024)

Subject Terms: obesity, brown adipocyte, beige adipocyte, PRDM16, UCP1, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fendo.2024.1458848/full; https://doaj.org/toc/1664-2392

Access URL: https://doaj.org/article/c6f2b07c10754310bb6e526fd350d2eb

Circulating plasma fibronectin affects tissue insulin sensitivity, adipocyte differentiation, and transcriptional landscape of adipose tissue in mice

Authors: Mahdokht Mahmoodi, Elahe Mirzarazi Dahagi, Mir‐Hamed Nabavi, Ylauna C. M. Penalva, Amrita Gosaine, Monzur Murshed, Sandrine Couldwell, Lisa M. Munter, Mari T. Kaartinen

Source: Physiological Reports, Vol 12, Iss 14, Pp n/a-n/a (2024)

Subject Terms: adipose tissue, beige adipocyte, extracellular matrix, insulin sensitivity, obesity, plasma fibronectin, Physiology, QP1-981

File Description: electronic resource

Relation: https://doaj.org/toc/2051-817X

Access URL: https://doaj.org/article/98eab24d4b3746e0a419bb46aede5a2e

Epigenetically active chromatin in neonatal iWAT reveals GABPα as a potential regulator of beige adipogenesis

Authors: Raja Gopal Reddy Mooli, Bokai Zhu, Saifur R. Khan, Veerababu Nagati, Kulandaimanuvel Antony Michealraj, Michael J. Jurczak, Sadeesh K. Ramakrishnan

Source: Frontiers in Endocrinology, Vol 15 (2024)

Subject Terms: beige adipocyte, neonatal adipose tissue, epigenetic modification, GABPA, subcutaneous adipose tissue, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fendo.2024.1385811/full; https://doaj.org/toc/1664-2392

Access URL: https://doaj.org/article/c67b53bffb8a42d4b4b60b741db8cbda

Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming

Authors: Corey D Holman, Alexander P Sakers, Ryan P Calhoun, Lan Cheng, Ethan C Fein, Christopher Jacobs, Linus Tsai, Evan D Rosen, Patrick Seale

Source: eLife, Vol 12 (2024)

Subject Terms: beige adipocyte, UCP1, cold exposure, aging, beige adipogenesis, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/87756; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/a87d04754b664275933a128e3f2ac78b

Alternative isoform expression of key thermogenic genes in human beige adipocytes

Authors: Sarah Hazell Pickering, Mohamed Abdelhalim, Philippe Collas, Nolwenn Briand

Source: Frontiers in Endocrinology, Vol 15 (2024)

Subject Terms: beige adipocyte, human thermogenic adipocytes, adipose differentiation, transcriptomics, alternative transcript isoforms, alternative splicing, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fendo.2024.1395750/full; https://doaj.org/toc/1664-2392

Access URL: https://doaj.org/article/4226de2cf38b407393d01b6cf67206a2

Thermogenic Fat as a New Obesity Management Tool: From Pharmaceutical Reagents to Cell Therapies

Authors: Ying Cheng, Shiqing Liang, Shuhan Zhang, Xiaoyan Hui

Source: Biomedicines, Vol 12, Iss 7, p 1474 (2024)

Subject Terms: brown adipose tissue, beige adipocyte, β3 adrenergic receptor, brown adipose tissue transplantation, human induced pluripotent stem cell, obesity, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/12/7/1474; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/3364c799ad8542d49f4b90804d525488

The Effect of KSK-94, a Dual Histamine H3 and Sigma-2 Receptor Ligand, on Adipose Tissue in a Rat Model of Developing Obesity

Authors: Magdalena Kotańska, Monika Zadrożna, Monika Kubacka, Kamil Mika, Katarzyna Szczepańska, Barbara Nowak, Alessio Alesci, Anthea Miller, Eugenia Rita Lauriano, Katarzyna Kieć-Kononowicz

Source: Pharmaceuticals, Vol 17, Iss 7, p 858 (2024)

Subject Terms: developing obesity, beige adipocyte, white adipose tissue browning, dual histamine H3 and sigma-2 receptor antagonist, Medicine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1424-8247/17/7/858; https://doaj.org/toc/1424-8247

Access URL: https://doaj.org/article/a89f1fff18ba46f69f8f2291d9821f40

Perirenal adipose tissue contains a subpopulation of cold-inducible adipocytes derived from brown-to-white conversion

Authors: Houyu Zhang, Yan Li, Carlos F Ibáñez, Meng Xie

Source: eLife, Vol 13 (2024)

Subject Terms: perirenal adipose tissue, browning, whitening, snRNA-seq, cold-inducible, beige adipocyte, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/93151; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/31f30b9ec13d4d74b221cd05436b8dac

H19X-encoded microRNAs induced by IL-4 in adipocyte precursors regulate proliferation to facilitate differentiation

Authors: Choijamts Munkhzul, Ji-Min Lee, Boseon Kim, Thi Thanh My Nguyen, Rehna Paula Ginting, Dahee Jeong, Young-Kook Kim, Min-Woo Lee, Mihye Lee

Source: Biology Direct, Vol 18, Iss 1, Pp 1-17 (2023)

Subject Terms: Adipocyte precursor, Interleukin-4, microRNA, Beige adipocyte, Proliferation, Wnt signaling, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1745-6150

Access URL: https://doaj.org/article/d3dbbfb4d1e448ad99e08224d17207d8

LSD1 in beige adipocytes protects cardiomyocytes against oxygen and glucose deprivation

Authors: Yiqiu Cao, Zhu Dong, Dongpeng Yang, Xiaowu Wang

Source: Iranian Journal of Basic Medical Sciences, Vol 26, Iss 1, Pp 30-36 (2023)

Subject Terms: beige adipocyte, cardiomyocyte, epicardial adipose tissue, lysine-specific demethylase 1, oxygen and glucose-deprivation, Medicine

File Description: electronic resource

Relation: https://ijbms.mums.ac.ir/article_21309_fa6f9bba6a8cd510a752b04e2d5dbcc2.pdf; https://doaj.org/toc/2008-3866; https://doaj.org/toc/2008-3874

Access URL: https://doaj.org/article/715102bba413412aa831634ab9ef0781

Effects of oleic acid and/or exercise on diet-induced thermogenesis and obesity in rats: involvement of beige adipocyte differentiation and macrophage M1 inhibition

Authors: Abeer Salama, Mohamed M Amin, Azza Hassan

Source: Research in Pharmaceutical Sciences, Vol 18, Iss 2, Pp 219-230 (2023)

Subject Terms: beige adipocyte, cd137, macrophage m1, oleic acid, tnf-α., Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2023;volume=18;issue=2;spage=219;epage=230;aulast=Salama; https://doaj.org/toc/1735-5362; https://doaj.org/toc/1735-9414

Access URL: https://doaj.org/article/eaf1edbad4314022a6bafe0074ba55b0

Neuroendocrine Control of Energy Metabolism

Contributors: Panzica, Giancarlo, Gotti, Stefano, Collado Guirao, Paloma

Subject Terms: IGF1, IGF2, IGFBP2, high-fat diet, obesity, sex differences, neuropeptides, beige adipocyte, white adipocyte, brown adipocyte, diabetes mellitus, differentiation, kisspeptin, AgRP, sheep, reproduction, LH, genistein, proopiomelanocortin, arcuate nucleus, rats, endocrine disrupting chemicals, bisphenol A, diethylstilbestrol, tributyltin, neuropeptide Y, pro-opiomelanocortin, phytoestrogens, endocrine disruptor, dimorphism, POMC, orexin, subfornical organ, organum vasculosum of the lamina terminalis, area postrema, hypothalamus, metabolism, diabetes, estrogens, gut permeability/integrity, insulin sensitivity, Akkermansia, gut microbiome, lactate, glycogen, behavior, learning, astrocytes, calcium signaling, energy balance, gliotransmission, systemic metabolism, amygdala, kisspeptins, food intake, body weight, intrauterine growth restriction, macrosomia, glucose tolerance, abdominal adipocyte gene expression, thrifty phenotype hypothesis, Medicine and Nursing, Neurosciences

File Description: image/jpeg

Access URL: https://directory.doabooks.org/handle/20.500.12854/81133
https://mdpi.com/books/pdfview/book/5164

Androgen Receptor is a Negative Regulator of PRDM16 in Beige Adipocyte

Authors: Shiting Zhao, Tao Nie, Lei Li, Qiaoyun Long, Ping Gu, Yuwei Zhang, Wei Sun, Zexin Lin, Qing Liu, Yue Qi, Wei Wang, Mengyuan Xie, Kerry Loomes, Chenleng Cai, Donghai Wu, Hannah Xiaoyan Hui

Source: Advanced Science, Vol 10, Iss 21, Pp n/a-n/a (2023)

Subject Terms: androgen, androgen receptor, beige adipocyte, PRDM16, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/bf2e8bac17d6416ea82ca942b3791b54

Thermogenic adipose tissue in energy regulation and metabolic health

Authors: Siwen Xue, Derek Lee, Daniel C. Berry

Source: Frontiers in Endocrinology, Vol 14 (2023)

Subject Terms: beige adipocyte, brown adipocyte development, aging, obesity, metabolism & endocrinology, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fendo.2023.1150059/full; https://doaj.org/toc/1664-2392

Access URL: https://doaj.org/article/0abf8fae86974319bbfe4c61c526f6ed

Induction of Browning in White Adipocytes: Fucoidan Characterization and Gold Nanoparticle Synthesis from Undaria pinnatifida Sporophyll Extract

Authors: Sun Young Park, Kangmin Park, Hye Mi Kang, Woo Chang Song, Jin-Woo Oh, Young-Whan Choi, Geuntae Park

Source: Marine Drugs, Vol 21, Iss 12, p 603 (2023)

Subject Terms: Undaria pinnatifida sporophyll extract, UPS-AuNPs, fucoidan, beige adipocyte, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/1660-3397/21/12/603; https://doaj.org/toc/1660-3397

Access URL: https://doaj.org/article/e6fca9400bb74e41b0c38ab0b58e744d

Chronic cAMP activation induces adipocyte browning through discordant biphasic remodeling of transcriptome and chromatin accessibility

Authors: Jisun So, Solaema Taleb, Jamie Wann, Olivia Strobel, Kyungchan Kim, Hyun Cheol Roh

Source: Molecular Metabolism, Vol 66, Iss , Pp 101619- (2022)

Subject Terms: Beige adipocyte, Transcriptome, Epigenome, NFIL3, Cellular reprogramming, Obesity, Internal medicine, RC31-1245

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212877822001880; https://doaj.org/toc/2212-8778

Access URL: https://doaj.org/article/57fd284c451e43e9a94e0400e2b1f35d

Nicotinamide-riboside shifts the differentiation of human primary white adipocytes to beige adipocytes impacting substrate preference and uncoupling respiration through SIRT1 activation and mitochondria-derived reactive species production

Authors: Lilla Nagy, Boglárka Rauch, Tamás Szerafin, Karen Uray, Attila Tóth, Péter Bai

Source: Frontiers in Cell and Developmental Biology, Vol 10 (2022)

Subject Terms: beige adipocyte, mitochondrial oxidation, nicotinamide riboside, uncoupled respiration, adipocyte differentiation, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2022.979330/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/0b0cb175a1b3487a8cc7c7efca6e2702