A deep learning framework for efficient pathology image analysis

Authors: Neidlinger, Peter, Lenz, Tim, Foersch, Sebastian, Loeffler, Chiara M. L., Clusmann, Jan, Gustav, Marco, Shaktah, Lawrence A., Langer, Rupert, Dislich, Bastian, Boardman, Lisa A., French, Amy J., Goode, Ellen L., Gsur, Andrea, Brezina, Stefanie, Gunter, Marc J., Steinfelder, Robert, Behrens, Hans-Michael, Röcken, Christoph, Harrison, Tabitha, Peters, Ulrike, Phipps, Amanda I., Curigliano, Giuseppe, Fusco, Nicola, Marra, Antonio, Hoffmeister, Michael, Brenner, Hermann, Kather, Jakob Nikolas

Subject Terms: Computer Science - Computer Vision and Pattern Recognition

Access URL: http://arxiv.org/abs/2502.13027

Benchmarking foundation models as feature extractors for weakly-supervised computational pathology

Authors: Neidlinger, Peter, Nahhas, Omar S. M. El, Muti, Hannah Sophie, Lenz, Tim, Hoffmeister, Michael, Brenner, Hermann, van Treeck, Marko, Langer, Rupert, Dislich, Bastian, Behrens, Hans Michael, Röcken, Christoph, Foersch, Sebastian, Truhn, Daniel, Marra, Antonio, Saldanha, Oliver Lester, Kather, Jakob Nikolas

Subject Terms: Electrical Engineering and Systems Science - Image and Video Processing, Computer Science - Computer Vision and Pattern Recognition

Access URL: http://arxiv.org/abs/2408.15823

Myocardial inflammatory cells in cardiac amyloidosis.

Authors: Simon, Philip¹ (AUTHOR), Behrens, Hans-Michael¹ (AUTHOR), Kristen, Arnt² (AUTHOR), Röcken, Christoph¹ (AUTHOR) christoph.roecken@uksh.de

Source: Scientific Reports. 10/10/2024, Vol. 14 Issue 1, p1-9. 9p.

Subject Terms: *PATHOLOGY, *HEART cells, *CARDIAC amyloidosis, *T cells, *CELL death

SMARCA4 and SMARCE1 in gastric cancer: Correlation with ARID1A, and microsatellite stability, and SMARCE1/ERBB2 co‐amplification

Authors: Pries, Katharina, Krüger, Sandra, Heckl, Steffen, Behrens, Hans‐Michael, Röcken, Christoph

Source: Cancer medicine. 12(9):10423-10437

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100184501055.0x000001&indx=1&recIds=ETOCvdc_100184501055.0x000001

Deep learning trained on lymph node status predicts outcome from gastric cancer histopathology: a retrospective multicentric study

Authors: Muti, Hannah S., Röcken, Christoph, Behrens, Hans-Michael, Löffler, Chiara M.L., Reitsam, Nic G., Grosser, Bianca, Märkl, Bruno, Stange, Daniel E., Jiang, Xiaofeng, Veldhuizen, Gregory P., Truhn, Daniel, Ebert, Matthias P., Grabsch, Heike I., Kather, Jakob N.

Source: In European Journal of Cancer November 2023 194

Complement 9 in amyloid deposits

Authors: Lux, Annelie, Gottwald, Juliane, Behrens, Hans-Michael, Daniel, Christoph, Amann, Kerstin, Röcken, Christoph

Source: Amyloid. 28(3):199-208

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125538372.0x000001&indx=1&recIds=ETOCvdc_100125538372.0x000001

p53 immunostaining cannot be used to predict TP53 mutations in gastric cancer: results from a large Central European cohort

Authors: Schoop, Isabelle, Maleki, Saffiyeh Saboor, Behrens, Hans-Michael, Krüger, Sandra, Haag, Jochen, Röcken, Christoph

Source: In Human Pathology November 2020 105:53-66

Therapy Resistance in Neoadjuvantly Treated Gastric Cancer and Cancer of the Gastroesophageal Junction is Associated with an Increased Expression of Immune Checkpoint Inhibitors—Comparison Against a Therapy Naïve Cohort

Authors: Schoop, Hauke, Bregenzer, Anna, Halske, Christine, Behrens, Hans-Michael, Krüger, Sandra, Egberts, Jan-Hendrik, Röcken, Christoph

Source: In Translational Oncology February 2020 13(2):165-176

Intratumoral heterogeneity and loss of ARID1A expression in gastric cancer correlates with increased PD-L1 expression in Western patients

Authors: Tober, Julia Maria, Halske, Christine, Behrens, Hans-Michael, Krüger, Sandra, Röcken, Christoph

Source: In Human Pathology December 2019 94:98-109

Stroma AReactive Invasion Front Areas (SARIFA) predict poor survival in adenocarcinomas of the stomach and gastrooesophageal junction: a validation study.

Authors: Ulase, Dita, Behrens, Hans-Michael, Röcken, Christoph

Source: Virchows Archiv: European Journal of Pathology; Sep2024, Vol. 485 Issue 3, p527-534, 8p

The expression of the insulin receptor in gastric cancer correlates with the HER2 status and may have putative therapeutic implications

Authors: Heckl, Steffen M., Wiesener, Viva, Behrens, Hans-Michael, Ulase, Dita, Krüger, Sandra, Röcken, Christoph

Source: Gastric cancer. 22(6):1130-1142

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100126238881.0x000001&indx=1&recIds=ETOCvdc_100126238881.0x000001

Expression of the potential therapeutic target claudin-18.2 is frequently decreased in gastric cancer: results from a large Caucasian cohort study

Authors: Dottermusch, Matthias, Krüger, Sandra, Behrens, Hans-Michael, Halske, Christine, Röcken, Christoph

Source: Virchows Archiv. 475(5):563-571

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125999940.0x000001&indx=1&recIds=ETOCvdc_100125999940.0x000001

Sexual dimorphism in gastric cancer: tumor-associated neutrophils predict patient outcome only for women

Authors: Clausen, Franziska, Behrens, Hans-Michael, Krüger, Sandra, Röcken, Christoph

Source: Journal of cancer research and clinical oncology. 146(1):53-66

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100118334240.0x000001&indx=1&recIds=ETOCvdc_100118334240.0x000001

Exploration of the Tumour Biological Significance of PCLO in Gastric Cancer: Results from a Large Central European Cohort.

Authors: Bernhardt, Maximilian¹ (AUTHOR), Behrens, Hans-Michael¹ (AUTHOR), Krüger, Sandra¹ (AUTHOR), Röcken, Christoph¹ (AUTHOR)

Source: Pathobiology. 2024, Vol. 91 Issue 3, p187-195. 9p.

FGFR2 overexpression and compromised survival in diffuse-type gastric cancer in a large central European cohort.

Authors: Schrumpf, Thorben¹ (AUTHOR), Behrens, Hans-Michael¹ (AUTHOR), Haag, Jochen¹ (AUTHOR), Krüger, Sandra¹ (AUTHOR), Röcken, Christoph¹ (AUTHOR) christoph.roecken@uksh.de

Source: PLoS ONE. 2/15/2022, Vol. 17 Issue 2, p1-19. 19p.

Subject Terms: *FIBROBLAST growth factor receptors, *FIBROBLAST growth factor 2, *STOMACH cancer, *GENE amplification, *GENETIC overexpression, *PROTEIN expression

Local vs. systemic pulmonary amyloidosis—impact on diagnostics and clinical management

Authors: Baumgart, Julius-Valentin, Stuhlmann-Laeisz, Christiane, Hegenbart, Ute, Nattenmüller, Johanna, Schönland, Stefan, Krüger, Sandra, Behrens, Hans-Michael, Röcken, Christoph

Source: Virchows Archiv. 473(5):627-637

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100126006390.0x000001&indx=1&recIds=ETOCvdc_100126006390.0x000001

Synchronous metastatic gastric cancer-molecular background and clinical implications with special attention to mismatch repair deficiency

Authors: Polom, Karol, Böger, Christine, Smyth, Elizabeth, Marrelli, Daniele, Behrens, Hans-Michael, Marano, Luigi, Becker, Thomas, Lordick, Florian, Röcken, Christoph, Roviello, Franco

Source: European journal of surgical oncology. 44(5):626-631

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100059937211.0x000001&indx=1&recIds=ETOCvdc_100059937211.0x000001

Subcellular compartmentalization of docking protein-1 contributes to progression in colorectal cancer

Authors: Friedrich, Teresa, Söhn, Michaela, Gutting, Tobias, Janssen, Klaus-Peter, Behrens, Hans-Michael, Röcken, Christoph, Ebert, Matthias P.A., Burgermeister, Elke

Source: In EBioMedicine June 2016 8:159-172

Establishing and validating the fluorescent amyloid ligand h-FTAA (heptamer formyl thiophene acetic acid) to identify transthyretin amyloid deposits in carpal tunnel syndrome

Authors: Hahn, Katharina, Nilsson, K. Peter R., Hammarström, Per, Urban, Peter, Meliss, Rolf Rüdiger, Behrens, Hans-Michael, Krüger, Sandra, Röcken, Christoph

Source: Amyloid. 24(2):78-86

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100097836491.0x000001&indx=1&recIds=ETOCvdc_100097836491.0x000001

Clinicopathologic Characteristics of Microsatellite Instable Gastric Carcinomas Revisited: Urgent Need for Standardization

Authors: Mathiak, Micaela, Warneke, Viktoria S., Behrens, Hans-Michael, Haag, Jochen, Böger, Christine, Krüger, Sandra, Röcken, Christoph

Source: Applied immunohistochemistry & molecular morphology. 25(1):12-24

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100050315124.0x000001&indx=1&recIds=ETOCvdc_100050315124.0x000001