Mitochondrial priming and response to BH3 mimetics in 'one-two punch' senogenic-senolytic strategies

Authors: Júlia López, Àngela Llop-Hernández, Sara Verdura, Eila Serrano-Hervás, Eva Martinez-Balibrea, Joaquim Bosch-Barrera, Eduard Teixidor, Eugeni López-Bonet, Begoña Martin-Castillo, Josep Sardanyés, Tomás Alarcón, Ruth Lupu, Elisabet Cuyàs, Javier A. Menendez

Source: Cell Death Discovery, Vol 11, Iss 1, Pp 1-16 (2025)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2058-7716

Access URL: https://doaj.org/article/612596be0f79401e9b4c171055786f0a

Fatty acid synthase (FASN) is a tumor-cell-intrinsic metabolic checkpoint restricting T-cell immunity

Authors: Elisabet Cuyàs, Stefano Pedarra, Sara Verdura, Miguel Angel Pardo, Roderic Espin Garcia, Eila Serrano-Hervás, Àngela Llop-Hernández, Eduard Teixidor, Joaquim Bosch-Barrera, Eugeni López-Bonet, Begoña Martin-Castillo, Ruth Lupu, Miguel Angel Pujana, Josep Sardanyès, Tomás Alarcón, Javier A. Menendez

Source: Cell Death Discovery, Vol 10, Iss 1, Pp 1-17 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2058-7716

Access URL: https://doaj.org/article/cf58d85bd0c34429bd80f33b1267b08a

Fatty acid synthase (FASN) signalome: A molecular guide for precision oncology

Authors: Javier A. Menendez, Elisabet Cuyàs, Jose Antonio Encinar, Travis Vander Steen, Sara Verdura, Àngela Llop‐Hernández, Júlia López, Eila Serrano‐Hervás, Sílvia Osuna, Begoña Martin‐Castillo, Ruth Lupu

Source: Molecular Oncology, Vol 18, Iss 3, Pp 479-516 (2024)

Subject Terms: cell fate, ferroptosis, immunotherapy, metastasis, mitochondrial priming, molecular glues, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

Access URL: https://doaj.org/article/d3a6d2c3332d4732a381d0b6a5d9a94b

Stratification of cancer and diabetes based on circulating levels of formate and glucose

Authors: Matthias Pietzke, Salvador Fernandez Arroyo, David Sumpton, Gillian M. Mackay, Begoña Martin-Castillo, Jordi Camps, Jorge Joven, Javier A. Menendez, Alexei Vazquez, On behalf of the METTEN study group

Source: Cancer & Metabolism, Vol 7, Iss 1, Pp 1-11 (2019)

Subject Terms: Cancer, Obesity, Biomarker, Serum metabolomics, Formate, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40170-019-0195-x; https://doaj.org/toc/2049-3002

Access URL: https://doaj.org/article/22428ceb5f4d4fe69c3782cb5800a37f

Metformin: Targeting the Metabolo-Epigenetic Link in Cancer Biology

Authors: Elisabet Cuyàs, Sara Verdura, Begoña Martin-Castillo, Javier A. Menendez

Source: Frontiers in Oncology, Vol 10 (2021)

Subject Terms: metformin, metabolism, epigenetics, chromatin, cancer, diet, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2020.620641/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/606f28326ee14f8b9a3c23043e8cc37f

Clinical Management of COVID-19 in Cancer Patients with the STAT3 Inhibitor Silibinin

Authors: Joaquim Bosch-Barrera, Ariadna Roqué, Eduard Teixidor, Maria Carmen Carmona-Garcia, Aina Arbusà, Joan Brunet, Begoña Martin-Castillo, Elisabet Cuyàs, Sara Verdura, Javier A. Menendez

Source: Pharmaceuticals, Vol 15, Iss 1, p 19 (2021)

Subject Terms: SARS-CoV-2, COVID-19, STAT3, silibinin, Legalon, COVID-GRAM score, Medicine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1424-8247/15/1/19; https://doaj.org/toc/1424-8247

Access URL: https://doaj.org/article/8b7ee1d49b544476a47992a5e8eac169

Metformin as an archetype immuno-metabolic adjuvant for cancer immunotherapy

Authors: Sara Verdura, Elisabet Cuyàs, Begoña Martin-Castillo, Javier A. Menendez

Source: OncoImmunology, Vol 8, Iss 10 (2019)

Subject Terms: metformin, immunotherapy, t-cells, immune checkpoints, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/bc8541831dc8455b8c5891d4f5d61214

The C Allele of ATM rs11212617 Associates With Higher Pathological Complete Remission Rate in Breast Cancer Patients Treated With Neoadjuvant Metformin

Authors: Elisabet Cuyàs, Maria Buxó, Maria José Ferri Iglesias, Sara Verdura, Sonia Pernas, Joan Dorca, Isabel Álvarez, Susana Martínez, Jose Manuel Pérez-Garcia, Norberto Batista-López, César A. Rodríguez-Sánchez, Kepa Amillano, Severina Domínguez, Maria Luque, Idoia Morilla, Agostina Stradella, Gemma Viñas, Javier Cortés, Jorge Joven, Joan Brunet, Eugeni López-Bonet, Margarita Garcia, Samiha Saidani, Xavier Queralt Moles, Begoña Martin-Castillo, Javier A. Menendez

Source: Frontiers in Oncology, Vol 9 (2019)

Subject Terms: metformin, breast cancer, neoadjuvancy, HER2, ATM, rs11212617, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fonc.2019.00193/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/d2338fd8195c45919755b3df06f89a20

Metformin Is a Direct SIRT1-Activating Compound: Computational Modeling and Experimental Validation

Authors: Elisabet Cuyàs, Sara Verdura, Laura Llorach-Parés, Salvador Fernández-Arroyo, Jorge Joven, Begoña Martin-Castillo, Joaquim Bosch-Barrera, Joan Brunet, Alfons Nonell-Canals, Melchor Sanchez-Martinez, Javier A. Menendez

Source: Frontiers in Endocrinology, Vol 9 (2018)

Subject Terms: metformin, SIRT1, aging, NAD+, NAD loss, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fendo.2018.00657/full; https://doaj.org/toc/1664-2392

Access URL: https://doaj.org/article/c7d9e1e1041d4fcb9bae970f349fbf99