ALSUntangled #70: caffeine

Authors: Hatch, Jessica, Barkhaus, Paul, Barnes, Benjamin, Beauchamp, Morgan, Benatar, Michael, Bertorini, Tulio, Bowser, Robert, Bromberg, Mark, Brown, Andrew, Mascias Cadavid, Javier, Carter, Gregory T., Cole, Nicholas, Crayle, Jesse, Dimachkie, Mazen, Ennist, David, Feldman, Eva, Fullam, Timothy, Heiman-Patterson, Terry, Jhooty, Sartaj, Levine, Todd, Li, Xiaoyan, Lund, Isaac, Mallon, Elise, Maragakis, Nicholas, McDermott, Christopher, Pattee, Gary, Pierce, Kaitlyn, Ratner, Dylan, Staats, Kim, Wicks, Paul, Wiedau, Martina, Bedlack, Richard

Source: Amyotrophic lateral sclerosis and frontotemporal degeneration. 24(7-8):766-770

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196181055.0x000001&indx=1&recIds=ETOCvdc_100196181055.0x000001

The amyotrophic lateral sclerosis-health index (ALS-HI): development and evaluation of a novel outcome measure

Authors: Varma, Anika, Weinstein, Jennifer, Seabury, Jamison, Rosero, Spencer, Zizzi, Christine, Alexandrou, Danae, Wagner, Ellen, Dilek, Nuran, Heatwole, John, Wuu, Joanne, Caress, James, Bedlack, Richard, Granit, Volkan, Statland, Jeffrey, Mehta, Paul, Benatar, Michael, Kaat, Aaron, Heatwole, Chad

Source: Amyotrophic lateral sclerosis and frontotemporal degeneration. 24(5-6):514-522

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195089985.0x000001&indx=1&recIds=ETOCvdc_100195089985.0x000001

ALSUntangled # 69: astaxanthin

Authors: Fullam, Timothy, Armon, Carmel, Barkhaus, Paul, Barnes, Benjamin, Beauchamp, Morgan, Benatar, Michael, Bertorini, Tulio, Bowser, Robert, Bromberg, Mark, Mascias Cadavid, Javier, Carter, Gregory T., Dimachkie, Mazen, Ennist, Dave, Feldman, Eva L., Heiman-patterson, Terry, Jhooty, Sartaj, Lund, Isaac, Mcdermott, Christopher, Pattee, Gary, Ratner, Dylan, Wicks, Paul, Bedlack, Richard

Source: Amyotrophic lateral sclerosis and frontotemporal degeneration. 24(5-6):553-557

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195089836.0x000001&indx=1&recIds=ETOCvdc_100195089836.0x000001

ALSUntangled #67: rituximab

Authors: Li, Xiaoyan, Armon, Carmel, Barkhaus, Paul, Barnes, Benjamin, Benatar, Michael, Bertorini, Tulio, Bromberg, Mark, Carter, Gregory T., Crayle, Jesse, Cudkowicz, Merit, Dimachkie, Mazen, Feldman, Eva L., Glass, Jonathan, Goslinga, Jill, Heiman-Patterson, Terry, Jhooty, Sartaj, Lichtenstein, Rachel, Lund, Isaac, Mcdermott, Christopher, Pattee, Gary, Pierce, Kaitlyn, Ratner, Dylan, Salmon, Kristiana, Wicks, Paul, Bedlack, Richard

Source: Amyotrophic lateral sclerosis and frontotemporal degeneration. 24(5-6):544-547

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195089676.0x000001&indx=1&recIds=ETOCvdc_100195089676.0x000001

ALSUntangled #68: ozone therapy

Authors: Sun, Yuyao, Barkhaus, Paul, Barnes, Benjamin, Beauchamp, Morgan, Benatar, Michael, Bertorini, Tulio, Bromberg, Mark, Carter, Gregory T., Crayle, Jesse, Cudkowicz, Merit, Dimachkie, Mazen, Feldman, Eva L., Fullam, Timothy, Heiman-Patterson, Terry, Jhooty, Sartaj, Lund, Isaac, Mcdermott, Christopher, Pattee, Gary, Pierce, Kaitlyn, Ratner, Dylan, Wicks, Paul, Bedlack, Richard

Source: Amyotrophic lateral sclerosis and frontotemporal degeneration. 24(5-6):548-552

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195089709.0x000001&indx=1&recIds=ETOCvdc_100195089709.0x000001

ALSUntangled #66: antimycobacterial antibiotics.

Authors: Pierce, Ellen S., Barkhaus, Paul, Beauchamp, Morgan, Bromberg, Mark, Carter, Gregory T., Goslinga, Jill, Greeley, David, Kihuwa-Mani, Sky, Levitsky, Gleb, Lund, Isaac, McDermott, Christopher, Pattee, Gary, Pierce, Kaitlyn, Polak, Meraida, Ratner, Dylan, Wicks, Paul, Bedlack, Richard

Source: Amyotrophic lateral sclerosis and frontotemporal degeneration. 24(5-6):539-543

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195089668.0x000001&indx=1&recIds=ETOCvdc_100195089668.0x000001

Design and Statistical Innovations in a Platform Trial for Amyotrophic Lateral Sclerosis

Authors: Quintana, Melanie, Saville, Benjamin R., Vestrucci, Matteo, Detry, Michelle A., Chibnik, Lori, Shefner, Jeremy, Berry, James D., Chase, Marianne, Andrews, Jinsy, Sherman, Alexander V., Yu, Hong, Drake, Kristin, Cudkowicz, Merit, Paganoni, Sabrina, Macklin, Eric A., Macklin, Eric, Hayden, Douglas, Lai, PoYing, Donahue, Rachel, Marion, Joseph, Alameda, Gustavo, Mathai, Nithya, Ho, Doreen, McCaffrey, Alexandra, Berry, James, Babu, Suma, Scalia, Jennifer, Freeman, Marlene, Tourenne, Clotilde Lagier, Sadri‐Vakili, Ghazaleh, Quick, Adam, Kolb, Stephen, Heintzman, Sarah, Heitzman, Daragh, Martin, Alan, Ajroud‐Driss, Senda, Sufit, Robert, Szymanski, April, Appel, Stanley H., Greene, Ericka (Simpson), Thonhoff, Jason, Shroff, Sheetal, Liao, Bing, Katz, Jonathan, Jenkins, Liberty, Felice, Kevin, Whitaker, Charles, Maragakis, Nicholas J., Clawson, Lora L., Uchil, Alpa, Riley, Kristen, Arneklev, JinAe, Simmons, Zachary, Grogan, James, Su, Xiaowei, Mamarabadi, Mansoureh, Goutman, Stephen A., Feldman, Eva, Olney, Nicholas, Bazan, Tracy, Miller, Timothy, Malcolm, Amber, Fernandes, Joseph Americo M., Piccione, Ezequiel, Thaisetthawatkul, Pariwat, Ilieva, Hristelina, Pasinelli, Piera, Jawdat, Omar, Farmakidis, Constantine, Jabari, Duaa, Statland, Jeffrey, Pasnoor, Mamatha, Dimachkie, Mazen, Weiss, Michael D, Rad, Nassim, Wang, Leo H., Foster, Laura, Vu, Tuan, Suresh, Niraja, Farias, Jerrica, Ladha, Shafeeq, Jacobsen, Bill, Milliard, Jourdan, Bowser, Robert, Owegi, Margaret Ayo, Brown, Robert H., Ghasemi, Mehdi, Houmani, Hajar, Douthwright, Catherine, Newman, Daniel S., Arcila‐Londono, Ximena, Steijlen, Kara, Yasek, Julia, Hams, Matthew, Jackson, Carlayne, Bhavaraju‐Sanka, Ratna, Swenson, Andrea, Nance, Christopher, Gutmann, Ludwig, Heiman‐Patterson, Terry, Deboo, Anahita, Caress, Jim, Cartwright, Michael, Fee, Dominic, Shrilla, David, Peltier, Amanda, Lewis, Richard, Burford, Matthew, Diaz, Frank, Rosenfeld, Jeffrey, Borg, David, Bhuvaneswaran, Karthikeyan, Walk, David, Maiser, Sam, Johnson, Kristin, Rao, Pooja, Elliott, Matthew, Rakocevic, Goran, Jones, Sarah, Solorzano, Guillermo, Kasarskis, Edward J., Mahuwala, Zabeen, Mathur Kumaraswamy, Vishakhadatta (Vish), Rutkove, Seward, McIlduff, Courtney, Bedlack, Richard, Li, Xiaoyan, Parker, Sarah, Elman, Lauren, Quinn, Colin, Goyal, Namita A., Habib, Ali A., Mozaffar, Tahseen, Korb, Manisha Kak, Mullen, Jeffrey, Rezania, Kourosh, Soliven, Betty, Roos, Raymond, Twydell, Paul, Mundwiler, Andrew, Young, Eufrosina, Meyer, Jenny A., Benatar, Michael, Glass, Jonathan, Fournier, Christina, Cohen, Jeffrey A., Stommel, Elijah, Robbins, Nathaniel M, Jones, Vovanti, Zilliox, Lindsay, Diaz‐Abad, Montserrat, Jin, Peter, Chauhan, Chandana, Wymer, James P., Chuquilin, Miguel, Subramony, S.H., McNeely, Whitney, Beydoun, Said R., Darki, Leila, Rodriguez, Rodrigo, Shah, Jaimin, Oskarsson, Bjorn, Pattee, Gary L., Bobenhouse, James, Hayat, Ghazala, Al‐Dahhak, Roula, Kafaie, Jafar, Martinez‐Thompson, Jennifer, Staff, Nathan, Nayar, Shakti, Kuenzler, Rebecca, Bayat, Elham, Rosow, Laura, Bodkin, Cynthia, Gursoy, Nurcan, Al‐Lahham, Tawfiq, Lacomis, David, Gibson, Summer, Rivner, Michael, Kushlaf, Hani A., Gwathmey, Kelly G., Elliott, Michael, McKinnon, Johnathan, Wu, Abel, Walsh, Alison, Whitesell, Jackie, Erickson, Amber, Locatelli, Eduardo, Connors, Robert, McCluskey, Leo, Usman, Uzma, Kovvuru, Sukanthi, Sherman, Alex, Hasenoehrl, Meredith, Dagostino, Derek, Faulconer, Kenneth, Kharakozova, Olga, Korin, Alexander, Tarasenko, Natalia, Vigneswaran, Prasha, Katsovskiy, Igor, Whitworth, Isaac, Wahab, Yusra, Novak, Ilya, Tustison, Eric, Jentoft, Katie, Ostrow, Joe, Changkuon, Genevive, La, Thuong, Deignan, Christina, Li, Haining, Patel, Payal, Phan, Minh, Hurwitz, Samuel, Estes, Michaela, Palillo, Jack, Thomas, Mirna, De Mattos, Annette, Patterson, Janae, Figueroa‐Szostek, Precious, Jean, Sandra Louis, Pothier, Lindsay, Harkey, Brittney, DiStefano, Sofia, Bailey, Abbey, Jordan, Boglarka, Pagliaro, Jaclyn, Wright, Spencer, Abu‐Hamdan, Natalie, Igne, Courtney, Kolvek, Taylor, Bailey, Jesse, Barlow, Victoria, Arroyave, Luisa, Henrique, Jennifer, Proeung, Serena, Rosenthal, Jesse, Gladden, Catherine, Cirino, Melissa, Henrique, Natalie, Deirmendjian, Emma, Small, Catherine, Bulat, Allison, Popel, Najla, Irwin, Liam, Hall, Meghan, Connolly, Mariah, Kittle, Gale, Hamilton, Jenny, De Santiago, Diana, Felix, Adrian, Lovett, Marlee, Nelson, Linda, Martin, Ashley, Garrett, Karly, Garcia, Abigail De La Rosa, Rede, Diana, Pabon, Marissa, Khan, Kamran, Fetouh, Ahmed, Woodcook, Joan, Kamp, Cornelia, Kennedy, Julie, McGarry, Andrew, Torti, Margherita

Source: Annals of neurology. 94(3):547-560

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191672083.0x000001&indx=1&recIds=ETOCvdc_100191672083.0x000001

Clenbuterol Treatment Is Safe and Associated With Slowed Disease Progression in a Small Open-Label Trial in Patients With Amyotrophic Lateral Sclerosis

Authors: Li, Xiaoyan, Koeberl, Dwight D., Lutz, Michael W., Bedlack, Richard

Source: Journal of clinical neuromuscular disease. 24(4):214-221

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191137383.0x000001&indx=1&recIds=ETOCvdc_100191137383.0x000001

ALSUntangled #65: glucocorticoid corticosteroids

Authors: Goslinga, Jill Ann, Terrelonge, Mark, Bedlack, Richard, Barkhaus, Paul, Barnes, Benjamin, Bertorini, Tulio, Bromberg, Mark, Carter, Gregory, Chen, Amy, Crayle, Jesse, Dimachkie, Mazen, Jiang, Leanne, Levitsky, Gleb, Lund, Isaac, Martin, Sarah, Mcdermott, Christopher, Pattee, Gary, Pierce, Kaitlyn, Ratner, Dylan, Slachtova, Lenka, Sun, Yuyao, Wicks, Paul

Source: Amyotrophic lateral sclerosis and frontotemporal degeneration. 24(3-4):351-357

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100189001173.0x000001&indx=1&recIds=ETOCvdc_100189001173.0x000001

An evaluation of the combination of sodium phenylbutyrate and taurursodiol for the treatment of amyotrophic lateral sclerosis

Authors: Sun, Yuyao, Li, Xiaoyan, Bedlack, Richard

Source: Expert review of neurotherapeutics. 23(1):1-7

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100177749828.0x000001&indx=1&recIds=ETOCvdc_100177749828.0x000001

ALSUntangled #63: ketogenic diets

Authors: Bedlack, Richard, Barkhaus, Paul E., Barnes, Benjamin, Beauchamp, Morgan, Bertorini, Tulio, Bromberg, Mark B., Carter, Gregory T., Chaudry, Vinay, Cudkowicz, Merit, Jackson, Ce, Levitsky, Gleb, Lund, Isaac, McDermott, Christopher, Novella, Steven, Olby, Natasha, Ostrow, Lyle, Pattee, Gary L., Heiman-Patterson, Terry, Ratner, Dylan, Salmon, Kristiana, Steves, Susan, Terrelonge, Mark, Wicks, Paul, Wills, Anne-Marie

Source: Amyotrophic lateral sclerosis and frontotemporal degeneration. 24(1-2):159-163

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100172565810.0x000001&indx=1&recIds=ETOCvdc_100172565810.0x000001

Adaptive Platform Trials to Transform Amyotrophic Lateral Sclerosis Therapy Development

Authors: Paganoni, Sabrina, Berry, James D., Quintana, Melanie, Macklin, Eric, Saville, Benjamin R., Detry, Michelle A., Chase, Marianne, Sherman, Alexander V., Yu, Hong, Drake, Kristin, Andrews, Jinsy, Shefner, Jeremy, Chibnik, Lori B., Vestrucci, Matteo, Cudkowicz, Merit E., Saville, Ben, Chibnik, Lori, Bind, Marie Abele, Chan, James, Locatelli, Eduardo, Alameda, Gustavo, Cudkowicz, Merit, McCaffrey, Alexandra, Berry, James, Babu, Suma, Nicholson, Katie, Scalia, Jennifer, Simmons, Zachary, Grogan, James, Su, Xiaowei, Mamarabadi, Mansoureh, Heitzman, Daragh, Nasri, Mohamad Asaad, Katz, Jonathan, Jenkins, Liberty, Felice, Kevin, Whitaker, Charles, Ajroud‐Driss, Senda, Quick, Adam, Kolb, Stephen, Sarah Heintzman, N. P., Appel, Stanley H., (Simpson) Greene, Ericka, Thonhoff, Jason, Shroff, Sheetal, Liao, Bing, Goutman, Stephen A., Feldman, Eva L., Miller, Timothy, Amber Malcolm, N. P., Newman, Daniel S., Arcila‐Londono, Ximena, Steijlen, Kara, Owegi, Margaret Ayo, Brown, Robert H., Ghasemi, Mehdi, Fernandes, Joseph Americo M., Piccione, Ezequiel, Thaisetthawatkul, Pariwat, Weiss, Michael D., Rad, Nassim, Ilieva, Hristelina, Pasinelli, Piera, Judith Guarnieri, N. P., Ladha, Shafeeq, Jacobsen, Bill, Bowser, Robert, Foster, Laura, Jackson, Carlayne, Rosenfeld, Jeffrey, Bhuvaneswaran, Karthikeyan, Elman, Lauren, Quinn, Colin, Julia Yasek, N. P., Fee, Dominic, Heiman‐Patterson, Terry, Deboo, Anahita, Swenson, Andrea, Nance, Christopher, Vu, Tuan, Suresh, Niraja, Farias, Jerrica, Caress, Jim, Cartwright, Michael, Rezania, Kourosh, Elliott, Matthew, Rutkove, Seward, McIlduff, Courtney, Cohen, Jeffrey A., Stommel, Elijah, Glass, Jonathan, Fournier, Christina, Young, Eufrosina, Wymer, James P., Granit, Volkan, Benatar, Michael, Lewis, Richard, Burford, Matthew, Diaz, Frank, Maragakis, Nicholas J., Clawson, Lora, Uchil, Alpa, Riley, Kristen, Mosmiller, Betsy, Twydell, Paul, Goyal, Namita A., Jawdat, Omar, Jabari, Duaa, Statland, Jeffrey, Kasarskis, Edward J., Russell, James W., Jin, Peter, Walk, David, Maiser, Sam, Shah, Jaimin, Oskarsson, Bjorn, Bedlack, Richard, Li, Xiaoyan, Chen, I‐Hweii Amy, Olney, Nicholas, Bazan, Tracy, Hayat, Ghazala, Pattee, Gary L., Donofrio, Peter D., Peltier, Amanda C., Martinez‐Thompson, Jennifer, Johnson, Kristin, Govindarajan, Raghav, Jones, Vovanti, Bertorini, Tulio, Tourenne, Clotilde Lagier, Vakili, Ghazaleh Sadri, Sherman, Alex, Dagostino, Derek, Bocchio, Scott, Eydinov, Matthew, Faulconer, Kenneth, Kharakozova, Olga, Korin, Alexander, Novak, Ilya, Sinani, Ervin, Tarasenko, Natalia, Vigneswaran, Prasha, Katsovskiy, Igor, Whitworth, Isaac, Wahab, Yusra, Gladden, Catherine, Shaughnessy, Aileen, Tustison, Eric, Jentoft, Katie, Ostrow, Joe, Lim, Sangwon, Changkuon, Genevive, Mattos, Annette De, Patterson, Janae, Scott, Robin, Figueroa‐Szostek, Precious, Pothier, Lindsay, Harkey, Brittney, DiStefano, Sofia, Kennedy, Erin, Bailey, Abbey, DiOrio, Nicole, Feulner, Jacob, Davis, Matt, Gomes, Jassira, DiMarzio, Marisa, Henrique, Jennifer, Benson, Molly, Grabert, Stacey, Garozzo, Tessa, Hall, Meghan, Randall, Rebecca, Connolly, Mariah, De Santiago, Diana, Lavery, Courtney, Kittle, Gale, Hamilton, Jenny, Bolger, Patrick, Fetouh, Ahmed, Kamp, Cornelia, Kennedy, Julie, Small, Catherine, Bulat, Allison, McGarry, Andrew, Torti, Margherita

Source: Annals of neurology. 91(2):165-175

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100139475865.0x000001&indx=1&recIds=ETOCvdc_100139475865.0x000001

Amyotrophic Lateral Sclerosis Clinical Trials and Interpretation of Functional End Points and Fluid BiomarkersA Review

Authors: Shefner, Jeremy M., Bedlack, Richard, Andrews, Jinsy A.

Source: JAMA neurology. 79(12):1312-1318

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN633373915&indx=1&recIds=ETOCRN633373915

ALSUntangled #62: vitamin C

Authors: Bedlack, Richard, Barkhaus, Paul, Carter, Greg, Crayle, Jesse, Mcdermott, Christopher, Pattee, Gary, Polak, Meraida, Salmon, Kristiana, Wicks, Paul

Source: Amyotrophic lateral sclerosis and frontotemporal degeneration. 23(5-6):476-479

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100175101611.0x000001&indx=1&recIds=ETOCvdc_100175101611.0x000001

ALSUntangled #64: butyrates

Authors: Sun, Yuyao, Bedlack, Richard, Armon, Carmel, Beauchamp, Morgan, Bertorini, Tulio, Bowser, Robert, Bromberg, Mark, Caress, James, Carter, Gregory, Crayle, Jesse, Cudkowicz, Merit E., Glass, Jonathan D., Jackson, Carlayne, Lund, Isaac, Martin, Sarah, Paganoni, Sabrina, Pattee, Gary, Ratner, Dylan, Salmon, Kristiana, Wicks, Paul

Source: Amyotrophic lateral sclerosis and frontotemporal degeneration. 23(7-8):638-643

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164655539.0x000001&indx=1&recIds=ETOCvdc_100164655539.0x000001

Phase 2B randomized controlled trial of NP001 in amyotrophic lateral sclerosis: Pre‐specified and post hoc analyses

Authors: Miller, Robert G., Zhang, Rongzhen, Bracci, Paige M., Azhir, Ari, Barohn, Richard, Bedlack, Richard, Benatar, Michael, Berry, James D., Cudkowicz, Merit, Kasarskis, Edward J., Mitsumoto, Hiroshi, Manousakis, Georgios, Walk, David, Oskarsson, Bjorn, Shefner, Jeremy, McGrath, Michael S.

Source: Muscle & nerve. 66(1):39-49

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100153933914.0x000001&indx=1&recIds=ETOCvdc_100153933914.0x000001

ALSUntangled #60: light therapy

Authors: Bedlack, Richard, Barkhaus, Paul, Barnes, Ben, Bereman, Michael, Bertorini, Tulio, Carter, Gregory, Crayle, Jesse, Kihuwa-Mani, Sky, Bowser, Robert, Kittrell, Pamela, McDermott, Christopher, Pattee, Gary, Salmon, Kristiana, Wicks, Paul

Source: Amyotrophic lateral sclerosis and frontotemporal degeneration. 23(3-4):315-319

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100148758444.0x000001&indx=1&recIds=ETOCvdc_100148758444.0x000001

The Scientific and Therapeutic Rationale for Off‐Label Treatments in Amyotrophic Lateral Sclerosis.

Authors: Bedlack, Richard¹ (AUTHOR) richard.bedlack@duke.edu, Li, Xiaoyan¹ (AUTHOR), Evangelista, Baggio Angelo² (AUTHOR), Panzetta, Maria E.³ (AUTHOR), Kwan, Justin⁴ (AUTHOR), Gittings, Lauren M.⁵ (AUTHOR), Sattler, Rita⁵ (AUTHOR)

Source: Annals of Neurology. Jan2025, Vol. 97 Issue 1, p15-27. 13p.

Subject Terms: *AMYOTROPHIC lateral sclerosis, *OXIDATIVE stress, *DRUG therapy, *NEUROINFLAMMATION, *MITOCHONDRIA

Safety and efficacy of oral levosimendan in people with amyotrophic lateral sclerosis (the REFALS study): a randomised, double-blind, placebo-controlled phase 3 trial

Authors: Kiernan, Matthew, Mathers, Susan, Henderson, Robert, Needham, Merrilee, Schultz, David, Löscher, Wolfgang, Mitrovic, Nenad, Rath, Jakob, Damme, Philip Van, De Bleecker, Jan L., Delstanche, Stéphanie, Johnston, Wendy, Zinman, Lorne, O'Connell, Colleen, Matte, Genevieve, Dionne, Annie, Korngut, Lawrence, Turnbull, John, Laaksovirta, Hannu, Jokela, Manu, Tapiola, Tero, Soriani, Marie-Hélène, Couratier, Philippe, Camu, William, Corcia, Philippe, Ludolph, Albert, Großkreutz, Julian, Meyer, Thomas, Boentert, Matthias, Schrank, Berthold, Prudlo, Johannes, Untucht, Robert, Hardiman, Orla, Siciliano, Gabriele, Chio', Adriano, Mazzini, Letizia, Inghilleri, Maurizio, Caponnetto, Claudia, Mora, Gabriele, Mora Pardina, Jesús S, Farrero Munoz, Eva, Vázquez Costa, Juan F, Aguera Morales, Eduardo, Varona, Luis, Andersen, Peter, Ingre, Caroline, Johansson, Rune, Radunovic, Aleksandar, Young, Carolyn, Babu, Suma, Shaibani, Aziz, Staff, Nathan, Vu, Tuan, Rivner, Michael, Scelsa, Stephen, Sivakumar, Kumaraswamy, Waheed, Waqar, Heitzman, Daragh, Rana, Sandeep, Pattee, Gary, Ajroud-Driss, Senda, Bayat, Elham, Kasarskis, Edward, Lange, Dale J, Elliott, Michael, Harris, Brent, Felice, Kevin, Pulley, Michael T, Kwan, Justin, Brown, Martin, Ravits, John, Burford, Matthew, Karam, Chafic, Miller, Timothy, Andrews, Jinsy, Levine, Todd, Locatelli, Eduardo, Wymer, James, Bedlack, Richard, Fee, Dominic, Goyal, Namita, Oskarsson, Bjorn, McCluskey, Leo, Caress, James, Weiss, Michael, Quick, Adam, Bromberg, Mark, Lacomis, David, Goutman, Stephen, Rezania, Kourosh, Guliani, Gaurav, Goslin, Kimberly, Katz, Jonathan S, Cudkowicz, Merit ^*, Genge, Angela, Maragakis, Nicholas, Petri, Susanne, van den Berg, Leonard, Aho, Valtteri V, Sarapohja, Toni, Kuoppamäki, Mikko, Garratt, Chris, Al-Chalabi, Ammar

Source: In The Lancet Neurology October 2021 20(10):821-831

MN-166 (ibudilast) in amyotrophic lateral sclerosis in a Phase IIb/III study: COMBAT-ALS study design

Authors: Oskarsson, Björn, Maragakis, Nicholas, Bedlack, Richard S, Goyal, Namita, Meyer, Jenny A, Genge, Angela, Bodkin, Cynthia, Maiser, Samuel, Staff, Nathan, Zinman, Lorne, Olney, Nicholas, Turnbull, John, Brooks, Benjamin Rix, Klonowski, Emelia, Makhay, Malath, Yasui, Seiichi, Matsuda, Kazuko

Source: Neurodegenerative disease management. 11(6):431-443

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191700901.0x000001&indx=1&recIds=ETOCvdc_100191700901.0x000001