A Novel Luminescence-Based High-Throughput Approach for Cellular Resolution of Protein Ubiquitination Using Tandem Ubiquitin Binding Entities (TUBEs)

Authors: Akinjiyan, Favour A., Fazal, Aleem, Hild, Marc, Beckwith, Rohan E. J., Ross, Nathan T., Paulk, Joshiawa, Carbonneau, Seth

Source: SLAS discovery. 25(4):350-360

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN623562382&indx=1&recIds=ETOCRN623562382

CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma

Authors: Ross, Nathan T., Lohmann, Felix, Carbonneau, Seth, Fazal, Aleem, Weihofen, Wilhelm A., Gleim, Scott, Salcius, Michael, Sigoillot, Frederic, Henault, Martin, Carl, Sarah H., Rodríguez-Molina, Juan B., Miller, Howard R., Brittain, Scott M., Murphy, Jason, Zambrowski, Mark, Boynton, Geoffrey, Wang, Yuan, Chen, Aye, Molind, Gregory J., Wilbertz, Johannes H., Artus-Revel, Caroline G., Jia, Min, Akinjiyan, Favour A., Turner, Jonathan, Knehr, Judith, Carbone, Walter, Schuierer, Sven, Reece-Hoyes, John S., Xie, Kevin, Saran, Chitra, Williams, Eric T., Roma, Guglielmo, Spencer, Matt, Jenkins, Jeremy, George, Elizabeth L., Thomas, Jason R., Michaud, Gregory, Schirle, Markus, Tallarico, John, Passmore, Lori A., Chao, Jeffrey A., Beckwith, Rohan E. J.

Source: Nature chemical biology. 16(1):50-59

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193389809.0x000001&indx=1&recIds=ETOCvdc_100193389809.0x000001

Structural and biophysical comparisons of the pomalidomide- and CC-220-induced interactions of SALL4 with cereblon.

Authors: Ma, Xiaolei, Leon, Barbara, Ornelas, Elizabeth, Dovala, Dustin, Tandeske, Laura, Luu, Catherine, Pardee, Gwynn, Widger, Stephania, Solomon, Jonathan M., Beckwith, Rohan E. J., Moser, Heinz, Clifton, Matthew C., Wartchow, Charles A.

Source: Scientific Reports; 12/12/2023, Vol. 13 Issue 1, p1-8, 8p

Subject Terms: ZINC proteins, MOLECULAR interactions, ZINC-finger proteins, GLUE

Catalytic Asymmetric Reactions for Organic Synthesis: The Combined C-H Activation/Siloxy-Cope Rearrangement.

Authors: Davies, Huw M. L., Beckwith, Rohan E. J.

Source: Journal of Organic Chemistry; December 24 2004, Vol. 69 Issue 26, p9241-9247, 7p

New Strategic Reactions for Organic Synthesis: Catalytic Asymmetric C-H Activation α to Oxygen as a Surrogate to the Aldol Reaction.

Authors: Davies, Huw M. L., Beckwith, Rohan E. J., Antoulinakis, Evan G.

Source: Journal of Organic Chemistry; August 8 2003, Vol. 68 Issue 16, p6126-6132, 7p

Catalytic Enantioselective C-H Activation by Means of Metal-Carbenoid-Induced C-H Insertion.

Authors: Davies, Huw M. L., Beckwith, Rohan E. J.

Source: Chemical Reviews; August 2003, Vol. 103 Issue 8, p2861-2903, 43p

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Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide.

Authors: Fischer, Eric S., Böhm, Kerstin, Lydeard, John R., Yang, Haidi, Stadler, Michael B., Cavadini, Simone, Nagel, Jane, Serluca, Fabrizio, Acker, Vincent, Lingaraju, Gondichatnahalli M., Tichkule, Ritesh B., Schebesta, Michael, Forrester, William C., Schirle, Markus, Hassiepen, Ulrich, Ottl, Johannes, Hild, Marc, Beckwith, Rohan E. J., Harper, J. Wade, Jenkins, Jeremy L.

Source: Nature. 8/6/2014, Vol. 512 Issue 7512, p49-53. 5p.

Subjects: ANTINEOPLASTIC agents, THALIDOMIDE, CARRIER proteins, TERATOGENICITY testing, MULTIPLE myeloma treatment, THERAPEUTICS

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Reactive carbon species tamed for synthesis.

Authors: Beckwith, Rohan E. J.

Source: Nature; 2/1/2018, Vol. 554 Issue 7690, p36-38, 3p, 1 Diagram

Author Correction: CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma

Authors: Ross, Nathan T., Lohmann, Felix, Carbonneau, Seth, Fazal, Aleem, Weihofen, Wilhelm A., Gleim, Scott, Salcius, Michael, Sigoillot, Frederic, Henault, Martin, Carl, Sarah H., Rodríguez-Molina, Juan B., Miller, Howard R., Brittain, Scott M., Murphy, Jason, Zambrowski, Mark, Boynton, Geoffrey, Wang, Yuan, Chen, Aye, Molind, Gregory J., Wilbertz, Johannes H., Artus-Revel, Caroline G., Jia, Min, Akinjiyan, Favour A., Turner, Jonathan, Knehr, Judith, Carbone, Walter, Schuierer, Sven, Reece-Hoyes, John S., Xie, Kevin, Saran, Chitra, Williams, Eric T., Roma, Guglielmo, Spencer, Matt, Jenkins, Jeremy, George, Elizabeth L., Thomas, Jason R., Michaud, Gregory, Schirle, Markus, Tallarico, John, Passmore, Lori A., Chao, Jeffrey A., Beckwith, Rohan E. J.

Source: Nature Chemical Biology; April 2020, Vol. 16 Issue: 4 p479-479, 1p

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Nucleophilic addition reactions of bridged triene η⁶-chromiumtricarbonyl complexes

Authors: Beckwith, Rohan E. J., Blake, Alexander J., Simpkins, Nigel S., Wilson, Claire, Gravestock, Michael B.

Source: Chemical Communications; July 7, 2000, Vol. 2000 Issue: 13 p1097-1098, 2p

Catalytic Asymmetric Reactions for Organic Synthesis: The Combined C-H Activation/Siloxy-Cope Rearrangement.

Authors: Davies, Huw M. L., Beckwith, Rohan E. J.

Source: ChemInform; May2005, Vol. 36 Issue 19, pno-no, 1p

Nucleophilic Addition Reactions of Bridged Triene η⁶-Chromiumtricarbonyl Complexes.

Authors: Beckwith, Rohan E. J., Gravestock, Michael B., Simpkins, Nigel S.

Source: ChemInform; Apr2003, Vol. 34 Issue 14, pno-no, 1p

ChemInform Abstract: Nucleophilic Addition Reactions of Bridged Triene η⁶-Chromiumtricarbonyl Complexes.

Authors: Beckwith, Rohan E. J., Blake, Alexander J., Gravestock, Michael B., Simpkins, Nigel S., Wilson, Claire

Source: ChemInform; Oct2000, Vol. 31 Issue 41, pno-no, 1p

Nucleophilic Addition Reactions of Bridged Triene η6‐Chromiumtricarbonyl Complexes.

Authors: Beckwith, Rohan E. J., Gravestock, Michael B., Simpkins, Nigel S.

Source: ChemInform; April 2003, Vol. 34 Issue: 14 pno-no

ChemInform Abstract: Nucleophilic Addition Reactions of Bridged Triene η6‐Chromiumtricarbonyl Complexes.

Authors: Beckwith, Rohan E. J., Blake, Alexander J., Gravestock, Michael B., Simpkins, Nigel S., Wilson, Claire

Source: ChemInform; October 2000, Vol. 31 Issue: 41 pno-no