Acquired alterations in nucleus accumbens responsiveness to a cocaine-paired discriminative stimulus preceding rats’ daily cocaine consumption

Authors: Estrin, David J., Kulik, Julianna M., Beacher, Nicholas J., Pawlak, Anthony P., Klein, Samuel D., West, Mark O.

Source: In Addiction Neuroscience December 2023 8

Striatal direct pathway neurons play leading roles in accelerating rotarod motor skill learning

Authors: Liang, Bo ^{1, 2, 7}, Zhang, Lifeng ^{1, 7}, Zhang, Yan ¹, Werner, Craig T. ¹, Beacher, Nicholas J. ¹, Denman, Alex J. ¹, Li, Yun ³, Chen, Rong ⁴, Gerfen, Charles R. ⁵, Barbera, Giovanni ^{1, ∗∗}, Lin, Da-Ting ^{1, 6, 8, ∗}

Source: In iScience 20 May 2022 25(5)

Detailed mapping of behavior reveals the formation of prelimbic neural ensembles across operant learning

Authors: Zhang, Yan, Denman, Alexander J., Liang, Bo, Werner, Craig T., Beacher, Nicholas J., Chen, Rong, Li, Yun, Shaham, Yavin, Barbera, Giovanni, Lin, Da-Ting

Source: In Neuron 16 February 2022 110(4):674-685

Emergence of negative affect as motivation for drug taking in rats chronically self-administering cocaine

Authors: Klein, Samuel D., Beacher, Nicholas J., Kulik, Julianna M., Estrin, David J., Pawlak, Anthony P., West, Mark O.

Source: Psychopharmacology. 237(5):1407-1420

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167712705.0x000001&indx=1&recIds=ETOCvdc_100167712705.0x000001

Individual differences in prelimbic neural representation of food and cocaine seeking

Authors: Glanzberg, Joseph T. ^{1, 6}, Denman, Alexander J. ^{1, 6}, Beacher, Nicholas J. ¹, Broomer, Matthew C. ¹, Liang, Bo ², Li, Yun ³, Shaham, Yavin ¹, Barbera, Giovanni ¹, Zhang, Yan ^{4, ∗}, Lin, Da-Ting ^{1, 5, 7, ∗∗}

Source: In Cell Reports 24 December 2024 43(12)

Characterization of operant social interaction in rats: effects of access duration, effort, peer familiarity, housing conditions, and choice between social interaction vs. food or remifentanil.

Authors: Chow, Jonathan J.¹ jonathan.chow@nih.gov, Beacher, Nicholas J.¹, Chabot, Jules M.¹, Oke, Marvellous¹, Venniro, Marco², Lin, Da-Ting¹, Shaham, Yavin¹ yshaham@intra.nida.nih.gov

Source: Psychopharmacology. Jul2022, Vol. 239 Issue 7, p2093-2108. 16p. 1 Chart, 4 Graphs.

Subject Terms: *SOCIAL interaction, *CHOICE (Psychology), *DRUG addiction, *HOUSING, *REMIFENTANIL

Examining a punishment-related brain circuit with miniature fluorescence microscopes and deep learning

Authors: Broomer, Matthew C., Beacher, Nicholas J., Wang, Michael W., Lin, Da-Ting

Source: In Addiction Neuroscience June 2024 11

Minibox: Custom solo or semi-group housing chambers for long term housing of rats with miniscopes

Authors: Beacher, Nicholas J. ^{a, ⁎}, Wang, Michael W. ^a, Broomer, Matthew C. ^a, Kuo, Jessica Y. ^b, Lin, Da-Ting ^{a, c}

Source: In MethodsX December 2024 13

A modular, cost-effective, versatile, open-source operant box solution for long-term miniscope imaging, 3D tracking, and deep learning behavioral analysis

Authors: Beacher, Nicholas J., Kuo, Jessica Y., Targum, Miranda, Wang, Michael, Washington, Kayden A., Barbera, Giovanna, Lin, Da-Ting

Source: In MethodsX June 2024 12

Using deep learning to study emotional behavior in rodent models.

Authors: Kuo, Jessica Y., Denman, Alexander J., Beacher, Nicholas J., Glanzberg, Joseph T., Yan Zhang, Yun Li, Da-Ting Lin

Source: Frontiers in Behavioral Neuroscience; 11/21/2022, Vol. 16, p1-9, 9p

Subject Terms: DEEP learning, ANIMAL behavior, SOCIAL anxiety, SOCIAL interaction

Dysbindin-1, BDNF, and GABAergic Transmission in Schizophrenia.

Authors: Jun, Rachel, Wen Zhang, Beacher, Nicholas J., Yan Zhang, Yun Li, Da-Ting Lin

Source: Frontiers in Psychiatry; 6/22/2022, Vol. 13, p1-7, 7p

Subject Terms: BRAIN-derived neurotrophic factor, SYNAPSES, NEURAL transmission, COGNITION disorders, SCHIZOPHRENIA, SYNAPTOGENESIS, NEUROPLASTICITY

Circuit Investigation of Social Interaction and Substance Use Disorder Using Miniscopes.

Authors: Beacher, Nicholas J., Washington, Kayden A., Werner, Craig T., Zhang, Yan, Barbera, Giovanni, Li, Yun, Lin, Da-Ting

Source: Frontiers in Neural Circuits; 10/5/2021, Vol. 15, p1-9, 9p

Subject Terms: SUBSTANCE abuse, SOCIAL interaction, BRAIN anatomy, REWARD (Psychology), ANIMAL behavior

Chronic Fentanyl Self-Administration Generates a Shift toward Negative Affect in Rats during Drug Use.

Authors: Dao, Angela N.¹ (AUTHOR) angela.dao@rutgers.edu, Beacher, Nicholas J.^1,2 (AUTHOR) nicholas.beacher@nih.gov, Mayr, Vivian¹ (AUTHOR) vvm19@scarletmail.rutgers.edu, Montemarano, Annalisa¹ (AUTHOR) am2454@scarletmail.rutgers.edu, Hammer, Sam¹ (AUTHOR) SHammer@epilepsygroup.com, West, Mark O.¹ (AUTHOR) markwest@rutgers.edu

Source: Brain Sciences (2076-3425). Aug2021, Vol. 11 Issue 8, p1064. 1p.

Subject Terms: *DRUG utilization, *FENTANYL, *SPRAGUE Dawley rats, *OPIOID abuse, *DRUG addiction