Predicting benefit from adjuvant therapy with corticosteroids in community-acquired pneumonia: a data-driven analysis of randomised trials

Authors: Smit, Jim M ^{a, e, *}, Van Der Zee, Philip A ^{a, b}, Stoof, Sara C M ^a, Van Genderen, Michel E ^a, Snijders, Dominic ^f, Boersma, Wim G ^g, Confalonieri, Paola ^h, Salton, Francesco ^h, Confalonieri, Marco ^h, Shih, Mei-Chiung ⁱ, Meduri, Gianfranco U ^j, Dequin, Pierre-François ^k, Le Gouge, Amélie ^l, Lloyd, Melanie ^m, Karunajeewa, Harin ⁿ, Bartminski, Grzegorz ⁿ, Fernández-Serrano, Silvia ^o, Suárez-Cuartín, Guillermo ^p, van Klaveren, David ^{c, q}, Briel, Matthias ^{r, s}, Schönenberger, Christof M ^r, Steyerberg, Ewout W ^t, Gommers, Diederik A M P J ^a, Bax, Hannelore I ^d, Bos, Wilem Jan W ^{u, v}, van de Garde, Ewoudt M W ^x, Wittermans, Esther ^v, Grutters, Jan C ^w, Blum, Claudine A ^{y, z}, Christ-Crain, Mirjam ^z, Torres, Antoni ^aa, Motos, Ana ^{ab, ac}, Reinders, Marcel J T ^e, Van Bommel, Jasper ^a, Krijthe, Jesse H ^e, Endeman, Henrik ^a

Source: In The Lancet Respiratory Medicine March 2025 13(3):221-233

Unraveling antibiotic resistance mechanisms in Mycobacterium abscessus: the potential role of efflux pumps

Authors: Mudde, Saskia E., Schildkraut, Jodie A., Ammerman, Nicole C., de Vogel, Corné P., de Steenwinkel, Jurriaan E.M., van Ingen, Jakko, Bax, Hannelore I.

Source: In Journal of Global Antimicrobial Resistance December 2022 31:345-352

Delamanid or pretomanid? A Solomonic judgement!

Authors: Mudde, Saskia E., Upton, Anna M., Lenaerts, Anne, Bax, Hannelore I., De Steenwinkel, Jurriaan E. M.

Source: Journal of antimicrobial chemotherapy. 77(4):880-902

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164054054.0x000001&indx=1&recIds=ETOCvdc_100164054054.0x000001

Altered fibrin network structure and fibrinolysis in intensive care unit patients with COVID‐19, not entirely explaining the increased risk of thrombosis

Authors: Vries, Judith J., Visser, Chantal, Geers, Lotte, Slotman, Johan A., van Kleef, Nadine D., Maas, Coen, Bax, Hannelore I., Miedema, Jelle R., Gorp, Eric C. M., Goeijenbier, Marco, Akker, Johannes P. C., Endeman, Henrik, Rijken, Dingeman C., Kruip, Marieke J. H. A., Maat, Moniek P. M.

Source: Journal of thrombosis and haemostasis. 20(6):1412-1420

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100150465887.0x000001&indx=1&recIds=ETOCvdc_100150465887.0x000001

Altered fibrin network structure and fibrinolysis in intensive care unit patients with COVID‐19, not entirely explaining the increased risk of thrombosis

Authors: de Vries, Judith J., Visser, Chantal, Geers, Lotte, Slotman, Johan A., van Kleef, Nadine D., Maas, Coen, Bax, Hannelore I., Miedema, Jelle R., van Gorp, Eric C.M., Goeijenbier, Marco, van den Akker, Johannes P.C., Endeman, Henrik, Rijken, Dingeman C., Kruip, Marieke J.H.A., de Maat, Moniek P.M. ^*

Source: In Journal of Thrombosis and Haemostasis June 2022 20(6):1412-1420

Relative Contributions of the Novel Diarylquinoline TBAJ-876 and its Active Metabolite to the Bactericidal Activity in a Murine Model of Tuberculosis.

Authors: Mudde, Saskia E, Ammerman, Nicole C, Kate, Marian T ten, Fotouhi, Nader, Lotlikar, Manisha U, Bax, Hannelore I, Steenwinkel, Jurriaan E M de

Source: Journal of Infectious Diseases; 12/15/2024, Vol. 230 Issue 6, pe1366-e1374, 9p

Subject Terms: MYCOBACTERIUM tuberculosis, LUNGS, LABORATORY mice, TUBERCULOSIS, ANIMAL disease models

Mycobacterium abscessus strain variability in preclinical drug development: does it really matter?

Authors: Mudde, Saskia E, Meliefste, Henriëtte M, Ammerman, Nicole C, Steenwinkel, Jurriaan E M de, Bax, Hannelore I

Source: Journal of Antimicrobial Chemotherapy (JAC); Dec2024, Vol. 79 Issue 12, p3169-3173, 5p

Subject Terms: MYCOBACTERIAL diseases, DRUG development, MYCOBACTERIUM, TREATMENT effectiveness, SUBSPECIES, IMIPENEM, AMIKACIN

The 2021 Dutch Working Party on Antibiotic Policy (SWAB) guidelines for empirical antibacterial therapy of sepsis in adults.

Authors: Sieswerda, Elske^1,2 (AUTHOR) e.sieswerda@umcutrecht.nl, Bax, Hannelore I.³ (AUTHOR), Hoogerwerf, Jacobien J.⁴ (AUTHOR), de Boer, Mark G. J.⁵ (AUTHOR), Boermeester, Marja⁶ (AUTHOR), Bonten, Marc J. M.² (AUTHOR), Dekker, Douwe⁷ (AUTHOR), van Wijk, Roy Gerth⁸ (AUTHOR), Juffermans, Nicole P.⁹ (AUTHOR), Kuindersma, Marnix¹⁰ (AUTHOR), van der Linden, Paul D.¹¹ (AUTHOR), Melles, Damian C.¹² (AUTHOR), Pickkers, Peter¹³ (AUTHOR), Schouten, Jeroen A.¹³ (AUTHOR), Rebel, Jasper R.¹⁴ (AUTHOR), van Zanten, Arthur R. H.¹⁵ (AUTHOR), Prins, Jan M.¹⁶ (AUTHOR), Wiersinga, W. Joost¹⁶ (AUTHOR)

Source: BMC Infectious Diseases. 8/11/2022, Vol. 22 Issue 1, p1-16. 16p.

Omadacycline as a promising new agent for the treatment of infections with Mycobacterium abscessus

Authors: Bax, Hannelore I, de Vogel, Corné P, Mouton, Johan W, de Steenwinkel, Jurriaan E M

Source: Journal of antimicrobial chemotherapy. 74(10):2930-2933

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100096846954.0x000001&indx=1&recIds=ETOCvdc_100096846954.0x000001

Treatment and Outcome of Culture-Confirmed Mycobacterium marinum Disease

Authors: Hendrikx, Louise, van Hees, Colette L M, de Steenwinkel, Jurriaan E M, Bax, Hannelore I, Sprong, Tom, Mulder, Bert, Jansz, Arjan, van Griethuysen, Arjanne, Bosboom, Ron, Stemerding, Annette, Koetsier, Marjolein, van Coevorden, Marco, Mourik, Bas C, Quint, Koen D, Ott, Alewijn, van Soolingen, Dick, Kuipers, Saskia, van Crevel, Reinout, van Ingen, Jakko

Source: Open forum infectious diseases. 9(4)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100163863443.0x000001&indx=1&recIds=ETOCvdc_100163863443.0x000001

The role of the time-kill kinetics assay as part of a preclinical modeling framework for assessing the activity of anti-tuberculosis drugs

Authors: Bax, Hannelore I., Bakker-Woudenberg, Irma A.J.M., de Vogel, Corné P., van der Meijden, Aart, Verbon, Annelies, de Steenwinkel, Jurriaan E.M.

Source: In Tuberculosis July 2017 105:80-85

Clinical and Virological Outcome of Monoclonal Antibody Therapies Across SARS-CoV-2 Variants in 245 Immunocompromised Patients: A Multicenter Prospective Cohort Study.

Authors: Huygens, Sammy, GeurtsvanKessel, Corine, Gharbharan, Arvind, Bogers, Susanne, Worp, Nathalie, Boter, Marjan, Bax, Hannelore I, Kampschreur, Linda M, Hassing, Robert-Jan, Fiets, Roel B, Levenga, Henriette, Afonso, Pedro Miranda, Koopmans, Marion, Rijnders, Bart J A, Munnink, Bas B Oude

Source: Clinical Infectious Diseases; 6/15/2024, Vol. 78 Issue 6, p1514-1521, 8p

Subject Terms: THERAPEUTIC use of monoclonal antibodies, T-cell lymphoma, MORTALITY, IMMUNIZATION, RESEARCH funding, VIRAL load, PATIENTS, IMMUNOCOMPROMISED patients, HOSPITAL care, HOSPITAL admission & discharge, TREATMENT effectiveness, DESCRIPTIVE statistics, LONGITUDINAL method, ANTIVIRAL agents, RESEARCH, ARTIFICIAL respiration, GENETIC mutation, COVID-19, B cell lymphoma, EVALUATION

Geographic Terms: NETHERLANDS

Mycobacterium chelonae, an 'atypical' cause of an LVAD driveline infection

Authors: Roest, Stefan, Bax, Hannelore I., Verkaik, Nelianne J., Brugts, Jasper J., Constantinescu, Alina A., de Bakker, Chantal C., Birim, Ozcan, Caliskan, Kadir, Manintveld, Olivier C.

Source: International journal of infectious diseases. 92:127-129

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100099710882.0x000001&indx=1&recIds=ETOCvdc_100099710882.0x000001

Signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations and disseminated coccidioidomycosis and histoplasmosis

Authors: Sampaio, Elizabeth P., Hsu, Amy P., Pechacek, Joseph, Bax, Hannelore I., Dias, Dalton L., Paulson, Michelle L., Chandrasekaran, Prabha, Rosen, Lindsey B., Carvalho, Daniel S., Ding, Li, Vinh, Donald C., Browne, Sarah K., Datta, Shrimati, Milner, Joshua D., Kuhns, Douglas B., Long Priel, Debra A., Sadat, Mohammed A., Shiloh, Michael, De Marco, Brendan, Alvares, Michael, Gillman, Jason W., Ramarathnam, Vivek, de la Morena, Maite, Bezrodnik, Liliana, Moreira, Ileana, Uzel, Gulbu, Johnson, Daniel, Spalding, Christine, Zerbe, Christa S., Wiley, Henry, Greenberg, David E., Hoover, Susan E., Rosenzweig, Sergio D., Galgiani, John N., Holland, Steven M.

Source: In The Journal of Allergy and Clinical Immunology June 2013 131(6):1624-1634

Clinical Characteristics and Outcomes of Immunocompromised Patients With Coronavirus Disease 2019 Caused by the Omicron Variant: A Prospective, Observational Study.

Authors: Malahe, S Reshwan K, Hoek, Rogier A S, Dalm, Virgil A S H, Broers, Annoek E C, Hoed, Caroline M den, Manintveld, Olivier C, Baan, Carla C, Deuzen, Charlotte M van, Papageorgiou, Grigorios, Bax, Hannelore I, Kampen, Jeroen J Van, Hellemons, Merel E, Kho, Marcia M L, Vries, Rory D de, Molenkamp, Richard, Reinders, Marlies E J, Rijnders, Bart J A

Source: Clinical Infectious Diseases; 2/1/2023, Vol. 76 Issue 3, pe172-e178, 7p

Subject Terms: THERAPEUTIC use of monoclonal antibodies, EVALUATION of medical care, STATISTICS, COVID-19, SARS-CoV-2, SCIENTIFIC observation, IMMUNOGLOBULINS, FRAIL elderly, IMMUNOCOMPROMISED patients, COVID-19 vaccines, CONVALESCENCE, GENETIC variation, PATIENTS, HOSPITAL admission & discharge, HOSPITAL care, DESCRIPTIVE statistics, HEMATOPOIETIC stem cell transplantation, LOGISTIC regression analysis, LONGITUDINAL method, TRANSPLANTATION of organs, tissues, etc., COMORBIDITY

Improving treatment outcome assessment in a mouse tuberculosis model

Authors: Mourik, Bas C., Svensson, Robin J., de Knegt, Gerjo J., Bax, Hannelore I., Verbon, Annelies, Simonsson, Ulrika S. H., de Steenwinkel, Jurriaan E. M.

Source: Scientific reports. 8(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131315921.0x000001&indx=1&recIds=ETOCvdc_100131315921.0x000001

127. Novel Treatment Approach for Left Ventricular Assist Device-related Infections

Authors: Yalcin, Yunus C, Verkaik, Nelianne, Bax, Hannelore I, Croughs, Peter D, Bogers, Ad J J C, Caliskan, Kadir

Source: Open forum infectious diseases. 6(Supplement 2):S92-S93

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100099683017.0x000001&indx=1&recIds=ETOCvdc_100099683017.0x000001

Predictive Modeling to Study the Treatment-Shortening Potential of Novel Tuberculosis Drug Regimens, Toward Bundling of Preclinical Data.

Authors: Mudde, Saskia E, Alsoud, Rami Ayoun, van der Meijden, Aart, Upton, Anna M, Lotlikar, Manisha U, Simonsson, Ulrika S H, Bax, Hannelore I, Steenwinkel, Jurriaan E M de, Ayoun Alsoud, Rami, de Steenwinkel, Jurriaan E M

Source: Journal of Infectious Diseases; 6/1/2022, Vol. 225 Issue 11, p1876-1885, 10p

Subject Terms: TUBERCULOSIS microbiology, DRUG therapy for tuberculosis, COMBINATION drug therapy, PYRAZINAMIDE, MYCOBACTERIUM tuberculosis, ANTITUBERCULAR agents, RESEARCH funding, RIFAMPIN, PHARMACODYNAMICS

Superior Efficacy of a Bedaquiline, Delamanid, and Linezolid Combination Regimen in a Mouse Tuberculosis Model.

Authors: Pieterman, Elise D, Keutzer, Lina, van der Meijden, Aart, van den Berg, Sanne, Wang, Han, Zimmerman, Matthew D, Simonsson, Ulrika S H, Bax, Hannelore I, Steenwinkel, Jurriaan E M de, de Steenwinkel, Jurriaan E M

Source: Journal of Infectious Diseases; 9/15/2021, Vol. 224 Issue 6, p1039-1047, 9p

Subject Terms: LABORATORY mice, LINEZOLID, LUNGS, SPLEEN, LOGISTIC regression analysis, TUBERCULIN test

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