A fully human monoclonal antibody possesses antibody‐dependent cellular cytotoxicity (ADCC) activity against the H1 subtype of influenza A virus by targeting a conserved epitope at the HA1 protomer interface

Authors: Gao, Rongyuan, Wang, Zhao, Uprety, Tirth, Sreenivasan, Chithra C., Sheng, Zizhang, Hause, Ben M., Brunick, Colin, Wu, Hua, Luke, Thomas, Bausch, Christoph L., Sullivan, Eddie J., Hoppe, Adam D., Huber, Victor C., Wang, Dan, Li, Feng

Source: Journal of medical virology. 95(7)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195125000.0x000001&indx=1&recIds=ETOCvdc_100195125000.0x000001

Human immunoglobulin from transchromosomic bovines hyperimmunized with SARS-CoV-2 spike antigen efficiently neutralizes viral variants

Authors: Liu, Zhuoming, Wu, Hua, Egland, Kristi A., Gilliland, Theron C., Dunn, Matthew D., Luke, Thomas C., Sullivan, Eddie J., Klimstra, William B., Bausch, Christoph L., Whelan, Sean P. J.

Source: Human vaccines & immunotherapeutics. 18(2)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100155260088.0x000001&indx=1&recIds=ETOCvdc_100155260088.0x000001

Polyclonal Antibodies Derived from Transchromosomic Bovines Vaccinated with the Recombinant F1-V Vaccine Increase Bacterial Opsonization In Vitro and Protect Mice from Pneumonic Plague.

Authors: Biryukov, Sergei S.¹, Wu, Hua², hwu@sab.bio, Dankmeyer, Jennifer L.¹, Rill, Nathaniel O.¹, Klimko, Christopher P.¹, Egland, Kristi A.², Shoe, Jennifer L.¹, Hunter, Melissa¹, Fetterer, David P.³, Qiu, Ju³, Davies, Michael L.¹, Bausch, Christoph L.², Sullivan, Eddie J.², Luke, Thomas², Cote, Christopher K.¹, hwu@sab.bio

Source: Antibodies (2073-4468); Jun2023, Vol. 12 Issue 2, p33, 16p

Increased Antibody Avidity and Cross-Neutralization of Severe Acute Respiratory Syndrome Coronavirus 2 Variants by Hyperimmunized Transchromosomic Bovine-Derived Human Immunoglobulins for Treatment of Coronavirus Disease 2019.

Authors: Tang, Juanjie, Grubbs, Gabrielle, Lee, Youri, Wu, Hua, Luke, Thomas C, Egland, Kristi A, Bausch, Christoph L, Sullivan, Eddie J, Khurana, Surender

Source: Journal of Infectious Diseases; 8/15/2022, Vol. 226 Issue 4, p655-663, 9p

Deciphering the Mechanisms of Therapeutic Protein Production.

Authors: Allison, Daniel W., Borgschulte, Trissa, Bausch, Christoph L.

Source: Chemical Engineering Progress; October 2007, Vol. 103 Issue 10, p48-52, 5p

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Human Monoclonal Antibody Derived from Transchromosomic Cattle Neutralizes Multiple H1 Clades of Influenza A Virus by Recognizing a Novel Conformational Epitope in the Hemagglutinin Head Domai.

Authors: Gao, Rongyuan¹, Sreenivasan, Chithra C.¹, Sheng, Zizhang², Hause, Ben M.³, Zhou, Bin⁴, Wentworth, David E.⁴, Clement, Travis³, Rausch, Dana³, Brunick, Colin⁵, Christopher-Hennings, Jane³, Hua Wu⁶, Bausch, Christoph L.⁶, Sullivan, Eddie J.⁶, Hoppe, Adam D.^7,8, Huber, Victor C.^5,8,9, Wang, Dan^1,8,9, Feng Li^1,8,9 feng.li@sdstate.edu

Source: Journal of Virology. Nov2020, Vol. 94 Issue 22, p1-17. 17p.

Subject Terms: *MONOCLONAL antibodies, *INFLUENZA A virus, *GLYCINE receptors, *INFLUENZA A virus, H1N1 subtype, *MEMBRANE glycoproteins, *AMINO acid residues