USP7 inactivation suppresses APC-mutant intestinal hyperproliferation and tumor development

Authors: Novellasdemunt, Laura, Kucharska, Anna, Baulies, Anna, Hutton, Colin, Vlachogiannis, Georgios, Repana, Dimitra, Rowan, Andrew, Suárez-Bonnet, A., Ciccarelli, Francesca, Valeri, Nicola, Li, Vivian S.W.

Source: Stem cell reports. 18(2):570-584

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182564985.0x000001&indx=1&recIds=ETOCvdc_100182564985.0x000001

STARD1 promotes NASH-driven HCC by sustaining the generation of bile acids through the alternative mitochondrial pathway

Authors: Conde de la Rosa, Laura, Garcia-Ruiz, Carmen, Vallejo, Carmen, Baulies, Anna, Nuñez, Susana, Monte, Maria J., Marin, Jose J.G., Baila-Rueda, Lucia, Cenarro, Ana, Civeira, Fernando, Fuster, Josep, Garcia-Valdecasas, Juan C., Ferrer, Joana, Karin, Michael, Ribas, Vicent, Fernandez-Checa, Jose C.

Source: In Journal of Hepatology June 2021 74(6):1429-1441

The Transcription Co-Repressors MTG8 and MTG16 Regulate Exit of Intestinal Stem Cells From Their Niche and Differentiation Into Enterocyte vs Secretory Lineages

Authors: Baulies, Anna, Angelis, Nikolaos, Foglizzo, Valentina, Danielsen, E. Thomas, Patel, Harshil, Novellasdemunt, Laura, Kucharska, Anna, Carvalho, Joana, Nye, Emma, De Coppi, Paolo, Li, Vivian S.W.

Source: In Gastroenterology October 2020 159(4):1328-1341

Endoplasmic Reticulum Stress-Induced Upregulation of STARD1 Promotes Acetaminophen-Induced Acute Liver Failure

Authors: Torres, Sandra, Baulies, Anna, Insausti-Urkia, Naroa, Alarcón-Vila, Cristina, Fucho, Raquel, Solsona-Vilarrasa, Estel, Núñez, Susana, Robles, David, Ribas, Vicent, Wakefield, Leslie, Grompe, Markus, Lucena, M. Isabel, Andrade, Raul J., Win, Sanda, Aung, Tin A., Kaplowitz, Neil, García-Ruiz, Carmen, Fernández-Checa, Jose C.

Source: In Gastroenterology August 2019 157(2):552-568

The effect of zinc acexamate on oxidative stress, inflammation and mitochondria induced apoptosis in rat model of renal warm ischemia

Authors: Hadj Abdallah, Najet, Baulies, Anna, Bouhlel, Ahlem, Bejaoui, Mohamed, Zaouali, Mohamed Amine, Ben Mimouna, Safa, Messaoudi, Imed, Fernandez-Checa, José Carlos, García Ruiz, Carmen, Ben Abdennebi, Hassen

Source: In Biomedicine & Pharmacotherapy September 2018 105:573-581

The 2-oxoglutarate carrier promotes liver cancer by sustaining mitochondrial GSH despite cholesterol loading

Authors: Baulies, Anna, Montero, Joan, Matías, Nuria, Insausti, Naroa, Terrones, Oihana, Basañez, Gorka, Vallejo, Carmen, Conde de La Rosa, Laura, Martinez, Laura, Robles, David, Morales, Albert, Abian, Joaquin, Carrascal, Montserrat, Machida, Keigo, Kumar, Dinesh B.U., Tsukamoto, Hidekazu, Kaplowitz, Neil, Garcia-Ruiz, Carmen, Fernández-Checa, José C.

Source: In Redox Biology April 2018 14:164-177

Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease

Authors: Torres, Sandra, Matías, Nuria, Baulies, Anna, Nuñez, Susana, Alarcon-Vila, Cristina, Martinez, Laura, Nuño, Natalia, Fernandez, Anna, Caballeria, Joan, Levade, Thierry, Gonzalez-Franquesa, Alba, Garcia-Rovés, Pablo, Balboa, Elisa, Zanlungo, Silvana, Fabrías, Gemma, Casas, Josefina, Enrich, Carlos, Garcia-Ruiz, Carmen, Fernández-Checa, José C.

Source: In Redox Biology April 2017 11:60-72

Wnt and Src signals converge on YAP‐TEAD to drive intestinal regeneration

Authors: Guillermin, Oriane, Angelis, Nikolaos, Sidor, Clara M, Ridgway, Rachel, Baulies, Anna, Kucharska, Anna, Antas, Pedro, Rose, Melissa R, Cordero, Julia, Sansom, Owen, Li, Vivian S W, Thompson, Barry J

Source: EMBO journal. 40(13)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135891646.0x000001&indx=1&recIds=ETOCvdc_100135891646.0x000001

Mitochondrial Cholesterol and the Paradox in Cell Death

Authors: García-Ruiz, Carmen, Ribas, Vicente, Baulies, Anna, Fernández-Checa, Jose C.

Source: Handbook of experimental pharmacology. 240:189-210

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN612836617&indx=1&recIds=ETOCRN612836617

ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitis

Authors: Fucho, Raquel, Martínez, Laura, Baulies, Anna, Torres, Sandra, Tarrats, Nuria, Fernandez, Anna, Ribas, Vicente, Astudillo, Alma M., Balsinde, Jesús, Garcia-Rovés, Pablo, Elena, Montserrat, Bergheim, Ina, Lotersztajn, Sophie, Trautwein, Christian, Appelqvist, Hanna, Paton, Adrienne W., Paton, James C., Czaja, Mark J., Kaplowitz, Neil, Fernandez-Checa, Jose C., García-Ruiz, Carmen

Source: In Journal of Hepatology November 2014 61(5):1126-1134

Endoplasmic Reticulum Stress Mediates Amyloid β Neurotoxicity via Mitochondrial Cholesterol Trafficking

Authors: Barbero-Camps, Elisabet, Fernández, Anna, Baulies, Anna, Martinez, Laura, Fernández-Checa, Jose C., Colell, Anna

Source: In The American Journal of Pathology July 2014 184(7):2066-2081

ASMase is required for chronic alcohol induced hepatic endoplasmic reticulum stress and mitochondrial cholesterol loading

Authors: Fernandez, Anna, Matias, Núria, Fucho, Raquel, Ribas, Vicente, Von Montfort, Claudia, Nuño, Natalia, Baulies, Anna, Martinez, Laura, Tarrats, Núria, Mari, Montserrat, Colell, Anna, Morales, Albert, Dubuquoy, Laurent, Mathurin, Philippe, Bataller, Ramón, Caballeria, Joan, Elena, Montserrat, Balsinde, Jesus, Kaplowitz, Neil, Garcia-Ruiz, Carmen, Fernandez-Checa, Jose C.

Source: In Journal of Hepatology October 2013 59(4):805-813

NEDD4 and NEDD4L regulate Wnt signalling and intestinal stem cell priming by degrading LGR5 receptor

Authors: Novellasdemunt, Laura, Kucharska, Anna, Jamieson, Cara, Prange‐Barczynska, Maria, Baulies, Anna, Antas, Pedro, van der Vaart, Jelte, Gehart, Helmuth, Maurice, Madelon M, Li, Vivian SW

Source: EMBO journal. 39(3)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100099792163.0x000001&indx=1&recIds=ETOCvdc_100099792163.0x000001

Intestinal Stem Cell Niche: The Extracellular Matrix and Cellular Components.

Authors: Meran, Laween¹, Baulies, Anna¹, Li, Vivian S. W.¹

Source: Stem Cells International. 8/1/2017, p1-11. 11p.

Subject Terms: *STEM cells, *EXTRACELLULAR matrix, *EPITHELIUM, *CRYPTS, *STROMAL cells, *SMOOTH muscle, *HOMEOSTASIS

Loss of ARID3A perturbs intestinal epithelial proliferation–differentiation ratio and regeneration

Authors: Angelis, Nikolaos, Baulies, Anna, Hubl, Florian, Kucharska, Anna, Kelly, Gavin, Llorian, Miriam, Boeing, Stefan, Li, Vivian S.W.

Source: The Journal of Experimental Medicine; October 2024, Vol. 221 Issue: 10 pe20232279-e20232279, 1p

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Engineering transplantable jejunal mucosal grafts using patient-derived organoids from children with intestinal failure

Authors: Meran, Laween, Massie, Isobel, Campinoti, Sara, Weston, Anne E., Gaifulina, Riana, Tullie, Lucinda, Faull, Peter, Orford, Michael, Kucharska, Anna, Baulies, Anna, Novellasdemunt, Laura, Angelis, Nikolaos, Hirst, Elizabeth, König, Julia, Tedeschi, Alfonso Maria, Pellegata, Alessandro Filippo, Eli, Susanna, Snijders, Ambrosius P., Collinson, Lucy, Thapar, Nikhil, Thomas, Geraint M. H., Eaton, Simon, Bonfanti, Paola, De Coppi, Paolo, Li, Vivian S. W.

Source: Nature Medicine; October 2020, Vol. 26 Issue: 10 p1593-1601, 9p

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Zinc mitigates renal ischemia‐reperfusion injury in rats by modulating oxidative stress, endoplasmic reticulum stress, and autophagy.

Authors: Hadj Abdallah, Najet, Baulies, Anna, Bouhlel, Ahlem, Bejaoui, Mohamed, Zaouali, Mohamed A., Ben Mimouna, Safa, Messaoudi, Imed, Fernandez‐Checa, José C., García Ruiz, Carmen, Ben Abdennebi, Hassen

Source: Journal of Cellular Physiology; Nov2018, Vol. 233 Issue 11, p8677-8690, 14p

Subject Terms: OXIDATIVE stress, REACTIVE oxygen species, REPERFUSION injury, APOPTOSIS, RETICULUM (Ruminants)