The Past in the Present: Spondylus , Place, and Identity

Authors: Bauer, Daniel E., Lunniss, Richard

Source: The Latin Americanist. 54(3):75-94

Availability: https://muse.jhu.edu/article/706469

Gene editing without ex vivo culture evades genotoxicity in human hematopoietic stem cells

Authors: Zeng, Jing ^{1, 2, 3, 4}, Nguyen, My Anh ^{1, 2, 3, 4}, Liu, Pengpeng ⁵, da Silva, Lucas Ferreira ^{1, 2, 3, 4, 6, 7}, Levesque, Sébastien ^{1, 2, 3, 4}, Lin, Linda Y. ^{1, 2, 3, 4}, Justus, David G. ^{7, 8}, Petri, Karl ^{6, 7}, Clement, Kendell ^{6, 7}, Porter, Shaina N. ⁹, Verma, Archana ^{1, 2, 3, 4}, Neri, Nola R. ^{1, 2, 3, 4}, Rosanwo, Tolulope ^{1, 2, 3, 4}, Ciuculescu, Marioara-Felicia ¹⁰, Abriss, Daniela ¹⁰, Mintzer, Esther ⁵, Maitland, Stacy A. ⁵, Demirci, Selami ¹¹, Cha, Hye Ji ^{1, 2, 3, 4, 13}, Orkin, Stuart H. ^{1, 2, 3, 4}, Tisdale, John F. ¹¹, Williams, David A. ^{1, 2, 3, 4}, Zhu, Lihua Julie ¹², Pruett-Miller, Shondra M. ⁹, Pinello, Luca ^{6, 7}, Joung, J. Keith ^{6, 7}, Pattanayak, Vikram ^{6, 7}, Manis, John P. ^{1, 2, 3, 4}, Armant, Myriam ¹⁰, Pellin, Danilo ^{1, 2, 3, 4}, Brendel, Christian ^{1, 2, 3, 4}, Wolfe, Scot A. ⁵, Bauer, Daniel E. ^{1, 2, 3, 4, 14, ∗}

Source: In Cell Stem Cell 6 February 2025 32(2):191-208

BCL11A +58/+55 enhancer-editing facilitates HSPC engraftment and HbF induction in rhesus macaques conditioned with a CD45 antibody-drug conjugate

Authors: Demirci, Selami ^{1, 9, ∗}, Zeng, Jing ^{2, 9}, Palchaudhuri, Rahul ³, Wu, Chuanfeng ⁴, Abraham, Diana M. ⁴, Hayal, Taha B. ⁴, Essawi, Khaled ⁵, Nguyen, My Anh ², Stasula, Ulana ¹, Chu, Rebecca ¹, Leonard, Alexis ¹, Porter, Shaina N. ⁶, Khan, Muhammad Behroz Naeem ¹, Hinojosa, Gabriela ¹, Uchida, Naoya ¹, Hong, Sogun ⁴, Lazzarotto, Cicera R. ⁷, Neri, Nola R. ², da Silva, Lucas Ferreira ², Pellin, Danilo ², Verma, Archana ², Lanieri, Leanne ³, Bhat, Anjali ³, Hammond, Katelyn ³, Tate, Tiffany ³, Maitland, Stacy A. ⁸, Sheikhsaran, Fatemeh ¹, Bonifacino, Aylin C. ⁴, Krouse, Allen E. ⁴, Linde, Nathaniel S. ⁴, Engels, Theresa ⁴, Golomb, Justin ⁴, Tsai, Shengdar Q. ⁷, Pruett-Miller, Shondra M. ⁶, Scadden, David T. ², Dunbar, Cynthia E. ⁴, Wolfe, Scot A. ⁸, Donahue, Robert E. ¹, Olson, Lisa M. ³, Bauer, Daniel E. ^{2, ∗∗}, Tisdale, John F. ^{1, 10, ∗∗∗}

Source: In Cell Stem Cell 6 February 2025 32(2):209-226

Ex vivo culture resting time impacts transplantation outcomes of genome-edited human hematopoietic stem and progenitor cells in xenograft mouse models

Authors: Demirci, Selami, Khan, Muhammad B.N., Hinojosa, Gabriela, Le, Anh, Leonard, Alexis, Essawi, Khaled, Gudmundsdottir, Bjorg, Liu, Xiong, Zeng, Jing, Inam, Zaina, Chu, Rebecca, Uchida, Naoya, Araki, Daisuke, London, Evan, Butt, Henna, Maitland, Stacy A., Bauer, Daniel E., Wolfe, Scot A., Larochelle, Andre, Tisdale, John F.

Source: In Cytotherapy June 2024 26(6):641-648

Base Editing of Human Hematopoietic Stem Cells

Authors: Zeng, Jing, Casirati, Gabriele, Nguyen, My Anh, Genovese, Pietro, Bauer, Daniel E.

Source: Methods in molecular biology. 2606:43-62

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN630960719&indx=1&recIds=ETOCRN630960719

Pre-existing immunity does not impair the engraftment of CRISPR-Cas9-edited cells in rhesus macaques conditioned with busulfan or radiation

Authors: Essawi, Khaled, Hakami, Waleed, Naeem Khan, Muhammad Behroz, Martin, Reid, Zeng, Jing, Chu, Rebecca, Uchida, Naoya, Bonifacino, Aylin C., Krouse, Allen E., Linde, Nathaniel S., Donahue, Robert E., Blobel, Gerd A., Gerdemann, Ulrike, Kean, Leslie S., Maitland, Stacy A., Wolfe, Scot A., Metais, Jean-Yves, Gottschalk, Stephen, Bauer, Daniel E., Tisdale, John F., Demirci, Selami

Source: In Molecular Therapy - Methods & Clinical Development 8 June 2023 29:483-493

Molecular Basis and Genetic Modifiers of Thalassemia

Authors: Tesio, Nicolò, Bauer, Daniel E.

Source: In Hematology/Oncology Clinics of North America April 2023 37(2):273-299

Development of a double shmiR lentivirus effectively targeting both BCL11A and ZNF410 for enhanced induction of fetal hemoglobin to treat β-hemoglobinopathies

Authors: Liu, Boya, Brendel, Christian, Vinjamur, Divya S., Zhou, Yu, Harris, Chad, McGuinness, Meaghan, Manis, John P., Bauer, Daniel E., Xu, Haiming, Williams, David A.

Source: Molecular therapy. 30(8):2693-2708

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100168291318.0x000001&indx=1&recIds=ETOCvdc_100168291318.0x000001

Direct delivery of Cas-embedded cytosine base editors as ribonucleoprotein complexes for efficient and accurate editing of clinically relevant targets.

Authors: Lee, Jeong Min, Zeng, Jing, Liu, Pengpeng, Nguyen, My Anh, Suchenski Loustaunau, Diego, Bauer, Daniel E, Kurt Yilmaz, Nese, Wolfe, Scot A, Schiffer, Celia A

Source: Nucleic Acids Research; 1/13/2025, Vol. 53 Issue 1, p1-13, 13p

Editing outside the body: Ex vivo gene-modification for β-hemoglobinopathy cellular therapy

Authors: Rosanwo, Tolulope O., Bauer, Daniel E.

Source: In Molecular Therapy 3 November 2021 29(11):3163-3178

Molecular analysis of the erythroid phenotype of a patient with BCL11A haploinsufficiency

Authors: Wessels, Marja W., Cnossen, Marjon H., van Dijk, Thamar B., Gillemans, Nynke, Schmidt, K. L. Juliëtte, van Lom, Kirsten, Vinjamur, Divya S., Coyne, Steven, Kurita, Ryo, Nakamura, Yukio, de Man, Stella A., Pfundt, Rolph, Azmani, Zakia, Brouwer, Rutger W.W., Bauer, Daniel E., van den Hout, Mirjam C.G.N., van IJcken, Wilfred F.J., Philipsen, Sjaak ^*

Source: In Blood Advances 11 May 2021 5(9):2339-2349

Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program

Authors: Hu, Yao, Stilp, Adrienne M., McHugh, Caitlin P., Rao, Shuquan, Jain, Deepti, Zheng, Xiuwen, Lane, John, Méric de Bellefon, Sébastian, Raffield, Laura M., Chen, Ming-Huei, Yanek, Lisa R., Wheeler, Marsha, Yao, Yao, Ren, Chunyan, Broome, Jai, Moon, Jee-Young, de Vries, Paul S., Hobbs, Brian D., Sun, Quan, Surendran, Praveen, Brody, Jennifer A., Blackwell, Thomas W., Choquet, Hélène, Ryan, Kathleen, Duggirala, Ravindranath, Heard-Costa, Nancy, Wang, Zhe, Chami, Nathalie, Preuss, Michael H., Min, Nancy, Ekunwe, Lynette, Lange, Leslie A., Cushman, Mary, Faraday, Nauder, Curran, Joanne E., Almasy, Laura, Kundu, Kousik, Smith, Albert V., Gabriel, Stacey, Rotter, Jerome I., Fornage, Myriam, Lloyd-Jones, Donald M., Vasan, Ramachandran S., Smith, Nicholas L., North, Kari E., Boerwinkle, Eric, Becker, Lewis C., Lewis, Joshua P., Abecasis, Goncalo R., Hou, Lifang, O’Connell, Jeffrey R., Morrison, Alanna C., Beaty, Terri H., Kaplan, Robert, Correa, Adolfo, Blangero, John, Jorgenson, Eric, Psaty, Bruce M., Kooperberg, Charles, Walton, Russell T., Kleinstiver, Benjamin P., Tang, Hua, Loos, Ruth J.F., Soranzo, Nicole, Butterworth, Adam S., Nickerson, Debbie, Rich, Stephen S., Mitchell, Braxton D., Johnson, Andrew D., Auer, Paul L., Li, Yun, Mathias, Rasika A., Lettre, Guillaume, Pankratz, Nathan, Laurie, Cathy C., Laurie, Cecelia A., Bauer, Daniel E., Conomos, Matthew P., Reiner, Alexander P.

Source: In The American Journal of Human Genetics 6 May 2021 108(5):874-893

Clonal hematopoiesis in sickle cell disease

Authors: Pincez, Thomas, Lee, Simon S.K., Ilboudo, Yann, Preuss, Michael, Pham Hung d'Alexandry d'Orengiani, Anne-Laure, Bartolucci, Pablo, Galactéros, Frédéric, Joly, Philippe, Bauer, Daniel E., Loos, Ruth J.F., Lindsley, R. Coleman, Lettre, Guillaume

Source: Blood. 138(21):2148-2152

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183247877.0x000001&indx=1&recIds=ETOCvdc_100183247877.0x000001

Small-Molecule PAPD5 Inhibitors Restore Telomerase Activity in Patient Stem Cells

Authors: Nagpal, Neha, Wang, Jianing, Zeng, Jing, Lo, Emily, Moon, Diane H., Luk, Kevin, Braun, Roman O., Burroughs, Lauri M., Keel, Sioban B., Reilly, Christopher, Lindsley, R. Coleman, Wolfe, Scot A., Tai, Albert K., Cahan, Patrick, Bauer, Daniel E., Fong, Yick W., Agarwal, Suneet

Source: In Cell Stem Cell 4 June 2020 26(6):896-909

End points for sickle cell disease clinical trials: renal and cardiopulmonary, cure, and low-resource settings

Authors: Farrell, Ann T. ^*, Panepinto, Julie, Desai, Ankit A. ^*, Kassim, Adetola A. ^*, Lebensburger, Jeffrey ^*, Walters, Mark C. ^*, Bauer, Daniel E., Blaylark, Rae M., DiMichele, Donna M., Gladwin, Mark T., Green, Nancy S., Hassell, Kathryn, Kato, Gregory J., Klings, Elizabeth S., Kohn, Donald B., Krishnamurti, Lakshmanan, Little, Jane, Makani, Julie, Malik, Punam, McGann, Patrick T., Minniti, Caterina, Morris, Claudia R., Odame, Isaac, Oneal, Patricia Ann, Setse, Rosanna, Sharma, Poornima, Shenoy, Shalini

Source: In Blood Advances 10 December 2019 3(23):4002-4020

Genome editing of HBG1 and HBG2 to induce fetal hemoglobin

Authors: Métais, Jean-Yves ^*, Doerfler, Phillip A. ^*, Mayuranathan, Thiyagaraj ^*, Bauer, Daniel E., Fowler, Stephanie C., Hsieh, Matthew M., Katta, Varun, Keriwala, Sagar, Lazzarotto, Cicera R., Luk, Kevin, Neel, Michael D., Perry, S. Scott, Peters, Samuel T., Porter, Shaina N., Ryu, Byoung Y., Sharma, Akshay, Shea, Devlin, Tisdale, John F., Uchida, Naoya, Wolfe, Scot A., Woodard, Kaitly J., Wu, Yuxuan, Yao, Yu, Zeng, Jing, Pruett-Miller, Shondra, Tsai, Shengdar Q., Weiss, Mitchell J.

Source: In Blood Advances 12 November 2019 3(21):3379-3392

Editing aberrant splice sites efficiently restores β-globin expression in β-thalassemia

Authors: Xu, Shuqian, Luk, Kevin, Yao, Qiuming, Shen, Anne H., Zeng, Jing, Wu, Yuxuan, Luo, Hong-Yuan, Brendel, Christian, Pinello, Luca, Chui, David H.K., Wolfe, Scot A. ^*, Bauer, Daniel E.

Source: In Blood 23 May 2019 133(21):2255-2262

FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity

Authors: Yien, Yvette Y., Shi, Jiahai, Chen, Caiyong, Cheung, Jesmine T.M., Grillo, Anthony S., Shrestha, Rishna, Li, Liangtao, Zhang, Xuedi, Kafina, Martin D., Kingsley, Paul D., King, Matthew J., Ablain, Julien, Li, Hojun, Zon, Leonard I., Palis, James, Burke, Martin D., Bauer, Daniel E., Orkin, Stuart H., Koehler, Carla M., Phillips, John D., Kaplan, Jerry, Ward, Diane M., Lodish, Harvey F., Paw, Barry H.

Source: In Journal of Biological Chemistry 21 December 2018 293(51):19797-19811

Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch

Authors: Liu, Nan, Hargreaves, Victoria V., Zhu, Qian, Kurland, Jesse V., Hong, Jiyoung, Kim, Woojin, Sher, Falak, Macias-Trevino, Claudio, Rogers, Julia M., Kurita, Ryo, Nakamura, Yukio, Yuan, Guo-Cheng, Bauer, Daniel E., Xu, Jian, Bulyk, Martha L., Orkin, Stuart H.

Source: In Cell 5 April 2018 173(2):430-442

Genetic therapies for sickle cell disease

Authors: Esrick, Erica B., Bauer, Daniel E.

Source: In Seminars in Hematology April 2018 55(2):76-86