The surface lipoproteins of gram-negative bacteria: Protectors and foragers in harsh environments

Authors: Cole, Gregory B., Bateman, Thomas J., Moraes, Trevor F.

Source: In Journal of Biological Chemistry January-June 2021 296

Application of Chimeric Mice with Humanized Liver for Study of Human-Specific Drug Metabolism

Authors: Bateman, Thomas J., Reddy, Vijay G.B., Kakuni, Masakazu, Morikawa, Yoshio, Kumar, Sanjeev ^{1, *}

Source: In Drug Metabolism and Disposition June 2014 42(6):1055-1065

Lymphatic Absorption, Metabolism, and Excretion of a Therapeutic Peptide in Dogs and Rats

Authors: Zou, Yan, Bateman, Thomas J., Adreani, Christine, Shen, Xiaolan, Cunningham, Paul K., Wang, Bo, Trinh, Tu, Christine, Amy, Hong, Xuening, Nunes, Christian N., Johnson, Chris V., Zhang, Andy S., Staskiewicz, Steve J., Braun, Matthew ¹, Kumar, Sanjeev ², Reddy, Vijay Bhasker G. ^*

Source: In Drug Metabolism and Disposition December 2013 41(12):2206-2214

Development of a novel class of potent and selective FIXa inhibitors

Authors: Zhang, Ting, Andre, Patrick, Bateman, Thomas J., Chen, Yi-Heng, Desai, Kunal, Ellsworth, Kenneth, Geissler, Wayne M., Guo, Liangqin, Hruza, Alan, Jian, Tianying, Meng, Dongfang, Parker, Dann L., Qian, Xiaoxia, Reichert, Paul, Sherer, Edward C., Shu, Min, Smith, Cameron J., Sonatore, Lisa M., Tschirret-Guth, Richard, Nolting, Andrew F., Orr, Robert, Campeau, Louis-Charles, Araki, Kazuto, Nishimura, Teruyuki, Sakurada, Isao, Wood, Harold B.

Source: Bioorganic & medicinal chemistry letters. 25(21):4945-4949

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100064270639.0x000001&indx=1&recIds=ETOCvdc_100064270639.0x000001

Chapter 29 - Drug discovery

Authors: Bateman, Thomas J.

Source: In Atkinson's Principles of Clinical Pharmacology Edition: Fourth Edition. 2022:563-572

Glutathione S-Transferase Catalyzed Desulfonylation of a Sulfonylfuropyridine

Authors: Bateman, Thomas J., Debenham, John S., Madsen-Duggan, Christina, Toupence, Richard B., Walsh, Thomas F., Truong, Quang, Bradley, Scott A., Doss, George A., Kumar, Sanjeev, Reddy, Vijay Bhasker G. ^*

Source: In Drug Metabolism and Disposition January 2010 38(1):108-114

A Slam-dependent hemophore contributes to heme acquisition in the bacterial pathogen Acinetobacter baumannii.

Authors: Bateman, Thomas J., Shah, Megha, Ho, Timothy Pham, Shin, Hyejin Esther, Pan, Chuxi, Harris, Greg, Fegan, Jamie E., Islam, Epshita A., Ahn, Sang Kyun, Hooda, Yogesh, Gray-Owen, Scott D., Chen, Wangxue, Moraes, Trevor F.

Source: Nature Communications; 11/1/2021, Vol. 12 Issue 1, p1-13, 13p

Subject Terms: ACINETOBACTER baumannii, HEME, HEMOPROTEINS, SERUM albumin, DRUG target, LOCUS (Genetics)

Contributors

Authors: Abernethy, Darrell R., Agoram, Balaji, Allen, John M., Arnold, Mark E., Atkinson, Arthur J., Jr., Bateman, Thomas J., Bergman, Kimberly, Booth, Brian, Boulton, David W., Branch, Robert A., Burckart, Gilbert J., Buschmann, Mary, Carmichael, Owen, Chamberlain, Christine, Chen, Ligong, Daniels, Charles E., Das, Promi, Delfino, Jana G., Van Den Anker, John N., Dreisbach, Albert W., Dyszel, Michael, Earp, Justin C., ElZarrad, M. Khair, Enogieru, Osatohanmwen J., Fletcher, Elimika Pfuma, Foster, David M., Frederiksen, Marilynn C., Galetin, Aleksandra, Garzone, Pamela D., Giacomini, Kathleen M., Gibbs, Megan A., Gilbert, Jack A, Gnjidic, Danijela, Gombar, Charles T., Grant, Denis M., Grudzinskas, Charles, Hamren, Bengt, Holford, Nicholas H.G., Huang, Shiew-Mei, Iacona, Renee, Isoherranen, Nina, Jin, Denise, Jones, Bridgette L., Kearns, Gregory L., Kortepeter, Cindy, Kunkoski, Elizabeth, Lau, S.W. Johnny, Leptak, Christopher, Lertora, Juan J.L., Lesko, Lawrence J., Liu, Jiang, Liu, Qi, Madabushi, Rajanikanth, Miller, Raymond, Mould, Diane R., Muñoz, Monica, Nolin, Thomas D., Noveck, Robert Joseph, Obach, R. Scott, Pacanowski, Michael, Paine, Mary F., Peck, Carl C., Ramamoorthy, Anuradha, Rodrigues, A. David, Rowland, Malcolm, Sahajwalla, Chandrahas G., Sahre, Martina Dagmar, Schuck, Robert N., Sharma, Khushboo, Sissung, Tristan, Stika, Catherine S., Takimoto, Chris H., Tomkinson, Helen, Uetrecht, Jack, Vicini, Paolo, Vo, Karen D., Wagner, John A., Wang, Yaning, Wang, Yow-Ming C., Wells, Peter G., Wick, Michael J., Yee, Sook Wah, Yin, Ophelia, Zgheib, Nathalie K., Zhang, Lei, Zhu, Hao

Source: In Atkinson's Principles of Clinical Pharmacology Edition: Fourth Edition. 2022:xvii-xx

Discovery of MK-8153, a Potent and Selective ROMK Inhibitor and Novel Diuretic/Natriuretic.

Authors: Jiang, Jinlong, Ding, Fa-Xiang, Zhou, Xiaoyan, Bateman, Thomas J., Dong, Shuzhi, Gu, Xin, Keh deJesus, Reynalda, Pio, Barbara, Tang, Haifeng, Chobanian, Harry R., Levorse, Dorothy, Hu, Mengwei, Thomas-Fowlkes, Brande, Margulis, Michael, Koehler, Martin, Weinglass, Adam, Gibson, Jack, Houle, Kevin, Yudkovitz, Joel, Hampton, Caryn

Source: Journal of Medicinal Chemistry; 6/10/2021, Vol. 64 Issue 11, p7691-7701, 11p

Prevalence of Slam-dependent hemophilins in Gram-negative bacteria.

Authors: Shin, Hyejin Esther¹, Chuxi Pan¹, Curran, David M.¹, Bateman, Thomas J.¹, Chong, Derrick H. Y.¹, Ng, Dixon¹, Shah, Megha¹, Moraes, Trevor F.¹, trevor.moraes@utoronto.ca

Source: Journal of Bacteriology; Jun2024, Vol. 206 Issue 6, p1-1, 1p

Development of a novel tricyclic class of potent and selective FIXa inhibitors

Authors: Meng, Dongfang, Andre, Patrick, Bateman, Thomas J., Berger, Richard, Chen, Yi-Heng, Desai, Kunal, Dewnani, Sunita, Ellsworth, Kenneth, Feng, Daming, Geissler, Wayne M., Guo, Liangqin, Hruza, Alan, Jian, Tianying, Li, Hong, Metzger, Joe, Parker, Dann L., Reichert, Paul, Sherer, Edward C., Smith, Cameron J., Sonatore, Lisa M., Tschirret-Guth, Richard, Wu, Jane, Xu, Jiayi, Zhang, Ting, Campeau, Louis-Charles, Orr, Robert, Poirier, Marc, McCabe-Dunn, Jamie, Araki, Kazuto, Nishimura, Teruyuki, Sakurada, Isao, Hirabayashi, Tomokazu, Wood, Harold B.

Source: In Bioorganic & Medicinal Chemistry Letters 15 November 2015 25(22):5437-5443

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

Synthesis and evaluation of N-[(1 S,2 S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-aminopropanamide as human cannabinoid-1 receptor (CB1R) inverse agonists

Authors: Du, Wu, Jewell, James P., Lin, Linus S., Colandrea, Vincent J., Xiao, Jing C., Lao, Julie, Shen, Chun-Pyn, Bateman, Thomas J., Reddy, Vijay B.G., Ha, Sookhee N., Shah, Shrenik K., Fong, Tung M., Hale, Jeffrey J., Hagmann, William K.

Source: In Bioorganic & Medicinal Chemistry Letters 2009 19(17):5195-5199

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.