Response of heterologously expressed pressure sensor-actuator-modulator macromolecule to external mechanical stress

Authors: Batabyal, Subrata, Idigo, Chinenye, Narcisse, Darryl, Dibas, Adnan, Mohanty, Samarendra ^⁎

Source: In Heliyon 30 April 2024 10(8)

Engineered sensor actuator modulator as aqueous humor outflow actuator for gene therapy of primary open-angle glaucoma.

Authors: Mohanty, Samarendra¹ (AUTHOR) smohanty@nanoscopetech.com, Batabyal, Subrata¹ (AUTHOR), Idigo, Chinenye¹ (AUTHOR), Narcisse, Darryl¹ (AUTHOR), Kim, Sanghoon¹ (AUTHOR), Al-Saad, Houssam¹ (AUTHOR), Carlson, Michael¹ (AUTHOR), Tchedre, Kissaou¹ (AUTHOR), Dibas, Adnan¹ (AUTHOR)

Source: Journal of Translational Medicine. 8/28/2024, Vol. 22 Issue 1, p1-13. 13p.

Subject Terms: *BILAYER lipid membranes, *AQUEOUS humor, *EYE infections, *OPEN-angle glaucoma, *INTRAOCULAR pressure

Layer-specific nanophotonic delivery of therapeutic opsin-encoding genes into retina

Authors: Batabyal, Subrata, Kim, Sanghoon, Wright, Weldon, Mohanty, Samarendra

Source: In Experimental Eye Research April 2021 205

Biodistribution of adeno‐associated virus type 2 carrying multi‐characteristic opsin in dogs following intravitreal injection

Authors: Tchedre, Kissaou T., Batabyal, Subrata, Galicia, Melissa, Narcisse, Darryl, Mustafi, Sourajit Mitra, Ayyagari, Ananta, Chavala, Sai, Mohanty, Samarendra K.

Source: Journal of cellular and molecular medicine. 25(18):8676-8686

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100128943187.0x000001&indx=1&recIds=ETOCvdc_100128943187.0x000001

Efficacy of Intravitreal Multi-Characteristic Opsin (MCO-010) Optogenetic Gene Therapy in a Mouse Model of Leber Congenital Amaurosis.

Authors: Dibas, Adnan¹ (AUTHOR), Batabyal, Subrata¹ (AUTHOR), Kim, Sanghoon¹ (AUTHOR), Carlson, Michael¹ (AUTHOR), Mohanty, Samarendra^1,2 (AUTHOR), Sharif, Najam A.² (AUTHOR) nsharif@nanostherapeutics.com

Source: Journal of Ocular Pharmacology & Therapeutics. Dec2024, Vol. 40 Issue 10, p702-708. 7p.

Subject Terms: *HEMATOXYLIN & eosin staining, *RETINAL diseases, *OPTICAL coherence tomography, *GENETIC mutation, *VISUAL training

Near-Infrared Laser-Based Spatially Targeted Nano-enhanced Optical Delivery of Therapeutic Genes to Degenerated Retina

Authors: Batabyal, Subrata, Gajjeraman, Sivakumar, Tchedre, Kissaou, Dibas, Adnan, Wright, Weldon, Mohanty, Samarendra

Source: In Molecular Therapy - Methods & Clinical Development 12 June 2020 17:758-770

Safety of intravitreally delivered AAV2 vector‐mediated multi‐characteristic opsin genetic construct in wild type beagle dogs.

Authors: Mohanty, Samarendra, Batabyal, Subrata, Ayyagari, Ananta, Sharif, Najam A.

Source: Journal of Gene Medicine; Jul2024, Vol. 26 Issue 7, p1-15, 15p

Nano-enhanced Optical Gene Delivery to Retinal Degenerated Mice

Authors: Batabyal, Subrata, Gajjeraman, Sivakumar, Bhattacharya, Sulagna, Wright, Weldon, Mohanty, Samarendra

Source: Current gene therapy. 19(5):318-329

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100099998204.0x000001&indx=1&recIds=ETOCvdc_100099998204.0x000001

Optical modulation and functional mapping of cortical activities using molecular actuator-sensor
Optogenetics and Optical Manipulation 2020

Authors: Narcisse, Darryl, Mustafi, Sourajit Mitra, Carlson, Michael, Batabyal, Subrata, Wright, Weldon, Mohanty, Samarendra

Source: Proceedings of SPIE, the International Society for Optical Engineering. 11227:1122704-1122704-4

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCCN900017258&indx=1&recIds=ETOCCN900017258

Laser‐assisted targeted gene delivery to degenerated retina improves retinal function

Authors: Batabyal, Subrata, Kim, Sanghoon, Wright, Weldon, Mohanty, Samarendra

Source: Journal of biophotonics. 14(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100114624416.0x000001&indx=1&recIds=ETOCvdc_100114624416.0x000001

Ultrafast interfacial solvation dynamics in specific protein DNA recognition

Authors: Batabyal, Subrata, Mondol, Tanumoy, Choudhury, Susobhan, Mazumder, Abhishek, Pal, Samir Kumar

Source: In Biochimie November 2013 95(11):2168-2176

Picosecond-resolved solvent reorganization and energy transfer in biological and model cavities

Authors: Batabyal, Subrata, Mondol, Tanumoy, Pal, Samir Kumar

Source: In Biochimie June 2013 95(6):1127-1135

Direct Observation of Kinetic Pathways of Biomolecular Recognition

Authors: Choudhury, Susobhan, Batabyal, Subrata, Mondal, Prasanna Kumar, Singh, Priya, Lemmens, Peter, Pal, Samir Kumar

Source: Chemistry. 21(45):16172-16177

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127384204.0x000001&indx=1&recIds=ETOCvdc_100127384204.0x000001

Dynamical perspective of protein-DNA interaction

Authors: Batabyal Subrata, Choudhury Susobhan, Sao Dilip, Mondol Tanumoy, Kumar Pal Samir

Source: Biomolecular Concepts, Vol 5, Iss 1, Pp 21-43 (2014)

Subject Terms: different dynamical conformations, molecular recognition, operator dna, photoinduced electron transfer, protein-dna interactions, protein-dna interface, resonance energy transfer, solvation dynamics, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1868-5021; https://doaj.org/toc/1868-503X

Access URL: https://doaj.org/article/baac72a782b54b48815aae0d73b0ea0a

Elucidating the structural and functional uniqueness of multi-characteristic opsin, a highly bioengineered, ambient light-sensitive molecule, with broadband spectral responsiveness and fast kinetics to modulate neural activities

Authors: Mohapatra, Pratyajit, Singh, Amir, Marks, William, Carlson, Michael, Batabyal, Subrata, Mohanty, Samarendra K.

Source: In Biophysical Journal 8 February 2024 123(3) Supplement 1:533a-533a

OCT guided micro-focal ERG system with multiple stimulation wavelengths for characterization of ocular health.

Authors: Carlson, Michael, Kim, Sanghoon, Aparicio-Domingo, Silvia, Li, Kang V., Puig, Ben, Batabyal, Subrata, Canto-Soler, M. Valeria, Mohanty, Samarendra

Source: Scientific Reports; 4/29/2022, Vol. 12 Issue 1, p1-12, 12p

Subject Terms: MELANOPSIN, RETINAL diseases, RETINAL degeneration, OPTICAL coherence tomography, WILD boar, DEGENERATION (Pathology)

Broad-Band Activatable White-Opsin.

Authors: Batabyal, Subrata¹, Cervenka, Gregory¹, Ha, Ji Hee², Kim, Young-tae³, Mohanty, Samarendra¹ smohanty@uta.edu

Source: PLoS ONE. 9/11/2015, Vol. 10 Issue 9, p1-13. 13p.

Subject Terms: *OPSINS, *OPTOGENETICS, *ARTIFICIAL retinas, *ELECTRODES, *LIGHT emitting diodes, *RHODOPSIN

Bioluminescent Multi-Characteristic Opsin for Simultaneous Optical Stimulation and Continuous Monitoring of Cortical Activities.

Authors: Narcisse, Darryl, Mustafi, Sourajit Mitra, Carlson, Michael, Batabyal, Subrata, Kim, Sanghoon, Wright, Weldon, Kumar Mohanty, Samarendra

Source: Frontiers in Cellular Neuroscience; 10/25/2021, Vol. 15, p1-17, 17p

Subject Terms: VISUAL cortex, BIOLUMINESCENCE, CIRCADIAN rhythms, SENSORIMOTOR integration, NEUROMODULATION

Monitoring Visual Cortical Activities During Progressive Retinal Degeneration Using Functional Bioluminescence Imaging.

Authors: Narcisse, Darryl, Mustafi, Sourajit M., Carlson, Michael, Kim, Sanghoon, Batabyal, Subrata, Wright, Weldon, Mohanty, Samarendra K.

Source: Frontiers in Neuroscience; 10/4/2021, Vol. 15, p1-12, 12p

Subject Terms: RETINAL degeneration, BIOLUMINESCENCE, VISUAL cortex, RETINITIS pigmentosa, OPTICAL coherence tomography

Pharmacologic fibroblast reprogramming into photoreceptors restores vision.

Authors: Mahato, Biraj, Kaya, Koray Dogan, Fan, Yan, Sumien, Nathalie, Shetty, Ritu A., Zhang, Wei, Davis, Delaney, Mock, Thomas, Batabyal, Subrata, Ni, Aiguo, Mohanty, Samarendra, Han, Zongchao, Farjo, Rafal, Forster, Michael J., Swaroop, Anand, Chavala, Sai H.

Source: Nature; 5/7/2020, Vol. 581 Issue 7806, p83-88, 6p, 10 Color Photographs, 2 Black and White Photographs, 1 Diagram, 1 Graph