TIFA renders intestinal epithelial cells responsive to microbial ADP-heptose and drives colonic inflammation in mice

Authors: Atreya, Imke ^h, Atreya, Raja ^h, Bacher, Petra ^{i, j}, Becker, Christoph ^h, Bojarski, Christian ^k, Britzen-Laurent, Nathalie ^l, Bosch-Voskens, Caroline ^m, Chang, Hyun-Dong ⁿ, Diefenbach, Andreas ^o, Günther, Claudia ^h, Hegazy, Ahmed N. ^k, Hildner, Kai ^h, Klose, Christoph S.N. ^o, Koop, Kristina ^h, Krug, Susanne ^k, Kühl, Anja A. ^k, Leppkes, Moritz ^h, López-Posadas, Rocío ^h, Ludwig, Leif S.-H. ^{p, q}, Neufert, Clemens ^h, Neurath, Markus ^h, Patankar, Jay V. ^h, Plattner, Christina ^r, Prüß, Magdalena ^h, Radbruch, Andreas ⁿ, Romagnani, Chiara ^s, Ronchi, Francesca ^o, Sanders, Ashley ^{k, q}, Scheffold, Alexander ⁱ, Schulzke, Jörg-Dieter ^k, Schumann, Michael ^k, Schürmann, Sebastian ^t, Siegmund, Britta ^k, Stürzl, Michael ^l, Trajanoski, Zlatko ^r, Triantafyllopoulou, Antigoni ⁿ, Waldner, Maximilian ^h, Weidinger, Carl ^k, Wirtz, Stefan ^h, Zundler, Sebastian ^h, Erkert, Lena ^a, Ruder, Barbara ^{a, 1}, Kabisch, Melanie ^a, Gamez Belmonte, Reyes ^a, Gonzalez Acera, Miguel ^a, Schödel, Lena ^a, Chiriac, Mircea T. ^a, Cineus, Roodline ^c, Gnafakis, Stylianos ^d, Leupold, Tamara ^a, Thoma, Oana-Maria ^{a, b}, Stolzer, Iris ^a, Taut, Astrid ^a, Thonn, Veronika ^a, Basic, Marijana ^g, Bleich, André ^g, Neurath, Markus F. ^{a, b}

Source: In Mucosal Immunology January 2025

Gut microbiota promote liver regeneration through hepatic membrane phospholipid biosynthesis

Authors: Yin, Yuhan, Sichler, Anna, Ecker, Josef, Laschinger, Melanie, Liebisch, Gerhard, Höring, Marcus, Basic, Marijana, Bleich, André, Zhang, Xue-Jun, Kübelsbeck, Ludwig, Plagge, Johannes, Scherer, Emely, Wohlleber, Dirk, Wang, Jianye, Wang, Yang, Steffani, Marcella, Stupakov, Pavel, Gärtner, Yasmin, Lohöfer, Fabian, Mogler, Carolin, Friess, Helmut, Hartmann, Daniel, Holzmann, Bernhard, Hüser, Norbert, Janssen, Klaus-Peter

Source: Journal of hepatology. 78(4):820-835

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186188291.0x000001&indx=1&recIds=ETOCvdc_100186188291.0x000001

Enhanced cultured diversity of the mouse gut microbiota enables custom-made synthetic communities

Authors: Afrizal, Afrizal, Jennings, Susan A.V., Hitch, Thomas C.A., Riedel, Thomas, Basic, Marijana, Panyot, Atscharah, Treichel, Nicole, Hager, Fabian T., Wong, Erin Oi-Yan, Wolter, Birger, Viehof, Alina, von Strempel, Alexandra, Eberl, Claudia, Buhl, Eva M., Abt, Birte, Bleich, André, Tolba, René, Blank, Lars M., Navarre, William W., Kiessling, Fabian, Horz, Hans-Peter, Torow, Natalia, Cerovic, Vuk, Stecher, Bärbel, Strowig, Till, Overmann, Jörg, Clavel, Thomas

Source: In Cell Host & Microbe 9 November 2022 30(11):1630-1645

Gut microbiota regulates optic nerve fiber myelination.

Authors: Ronchi, Giulia, Pellegrino, Davide, El Soury, Marwa, Amato, Olga, Gaia, Francesco, Farzin, Sajjad, Nuzzi, Raffaele, Basic, Marijana, Bolsega, Silvia, Geuna, Stefano, Cescon, Matilde, Haastert-Talini, Kirsten, Gambarotta, Giovanna

Source: Frontiers in Cell & Developmental Biology; 2025, p1-13, 13p

Subject Terms: OPTIC nerve, MYELINATION, GUT microbiome, RETINAL diseases, TRANSCRIPTION factors, MICE

Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis

Authors: Hinrichsen, Finn, Hamm, Jacob, Westermann, Magdalena, Schröder, Lena, Shima, Kensuke, Mishra, Neha, Walker, Alesia, Sommer, Nina, Klischies, Kenneth, Prasse, Daniela, Zimmermann, Johannes, Kaiser, Sina, Bordoni, Dora, Fazio, Antonella, Marinos, Georgios, Laue, Georg, Imm, Simon, Tremaroli, Valentina, Basic, Marijana, Häsler, Robert, Schmitz, Ruth A., Krautwald, Stefan, Wolf, Andrea, Stecher, Bärbel, Schmitt-Kopplin, Philippe, Kaleta, Christoph, Rupp, Jan, Bäckhed, Fredrik, Rosenstiel, Philip, Sommer, Felix

Source: In Cell Metabolism 7 December 2021 33(12):2355-2366

E. coli enhance colonization resistance against Salmonella Typhimurium by competing for galactitol, a context-dependent limiting carbon source

Authors: Eberl, Claudia, Weiss, Anna S., Jochum, Lara M., Durai Raj, Abilash Chakravarthy, Ring, Diana, Hussain, Saib, Herp, Simone, Meng, Chen, Kleigrewe, Karin, Gigl, Michael, Basic, Marijana, Stecher, Bärbel

Source: In Cell Host & Microbe 10 November 2021 29(11):1680-1692

Monitoring and contamination incidence of gnotobiotic experiments performed in microisolator cages

Authors: Basic, Marijana, Bolsega, Silvia, Smoczek, Anna, Gläsner, Joachim, Hiergeist, Andreas, Eberl, Claudia, Stecher, Bärbel, Gessner, André, Bleich, André ^*

Source: In International Journal of Medical Microbiology April 2021 311(3)

S100A8 and S100A9 Are Important for Postnatal Development of Gut Microbiota and Immune System in Mice and Infants

Authors: Willers, Maike, Ulas, Thomas, Völlger, Lena, Vogl, Thomas, Heinemann, Anna S., Pirr, Sabine, Pagel, Julia, Fehlhaber, Beate, Halle, Olga, Schöning, Jennifer, Schreek, Sabine, Löber, Ulrike, Essex, Morgan, Hombach, Peter, Graspeuntner, Simon, Basic, Marijana, Bleich, Andre, Cloppenborg-Schmidt, Katja, Künzel, Sven, Jonigk, Danny, Rupp, Jan, Hansen, Gesine, Förster, Reinhold, Baines, John F., Härtel, Christoph, Schultze, Joachim L., Forslund, Sofia K., Roth, Johannes, Viemann, Dorothee

Source: In Gastroenterology December 2020 159(6):2130-2145

Temporally Distinct Functions of the Cytokines IL-12 and IL-23 Drive Chronic Colon Inflammation in Response to Intestinal Barrier Impairment

Authors: Eftychi, Christina, Schwarzer, Robin, Vlantis, Katerina, Wachsmuth, Laurens, Basic, Marijana, Wagle, Prerana, Neurath, Markus F., Becker, Christoph, Bleich, André, Pasparakis, Manolis

Source: In Immunity 20 August 2019 51(2):367-380

Mucispirillum schaedleri Antagonizes Salmonella Virulence to Protect Mice against Colitis

Authors: Herp, Simone, Brugiroux, Sandrine, Garzetti, Debora, Ring, Diana, Jochum, Lara M., Beutler, Markus, Eberl, Claudia, Hussain, Saib, Walter, Steffi, Gerlach, Roman G., Ruscheweyh, Hans J., Huson, Daniel, Sellin, Mikael E., Slack, Emma, Hanson, Buck, Loy, Alexander, Baines, John F., Rausch, Philipp, Basic, Marijana, Bleich, André, Berry, David, Stecher, Bärbel

Source: In Cell Host & Microbe 8 May 2019 25(5):681-694

Analysis of Cdcs1 colitogenic effects in the hematopoietic compartment reveals distinct microbiome interaction and a new subcongenic interval active in T cells

Authors: Bruesch, Inga ^*, Meier, Pascal, Vital, Marius, Pieper, Dietmar H., Selke, Kristin, Böhlen, Sebastian, Basic, Marijana, Meier, Martin ^*, Glage, Silke, Hundrieser, Joachim, Wedekind, Dirk, Buettner, Manuela, Bleich, André

Source: In Mucosal Immunology May 2019 12(3):691-702

Akkermansia muciniphila strain ATCC BAA-835 does not promote short-term intestinal inflammation in gnotobiotic interleukin-10-deficient mice

Authors: Ring, Christiane, Klopfleisch, Robert, Dahlke, Katja, Basic, Marijana, Bleich, André, Blaut, Michael

Source: Gut microbes. 10(2):188-203

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100079386442.0x000001&indx=1&recIds=ETOCvdc_100079386442.0x000001

Approaches to discern if microbiome associations reflect causation in metabolic and immune disorders

Authors: Basic, Marijana [and others]

Source: Gut microbes. 14(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190509648.0x000001&indx=1&recIds=ETOCvdc_100190509648.0x000001

Upregulation of antimicrobial peptide expression in slc26a3-/- mice with colonic dysbiosis and barrier defect

Authors: Kini, Archana, Zhao, Bei, Basic, Marijana, Roy, Urmi, Iljazovic, Aida, Odak, Ivan, Ye, Zhenghao, Riederer, Brigitte, Di Stefano, Gabriella, Römermann, Dorothee, Koenecke, Christian, Bleich, André, Strowig, Till, Seidler, Ursula

Source: Gut microbes. 14(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100176350748.0x000001&indx=1&recIds=ETOCvdc_100176350748.0x000001

Regulation of epithelial cell expressed C3 in the intestine – Relevance for the pathophysiology of inflammatory bowel disease?

Authors: Sünderhauf, Annika, Skibbe, Kerstin, Preisker, Sophie, Ebbert, Karen, Verschoor, Admar, Karsten, Christian M., Kemper, Claudia, Huber-Lang, Markus, Basic, Marijana, Bleich, André, Büning, Jürgen, Fellermann, Klaus, Sina, Christian, Derer, Stefanie

Source: In Molecular Immunology October 2017 90:227-238

Enhancement of IFNγ Production by Distinct Commensals Ameliorates Salmonella-Induced Disease

Authors: Thiemann, Sophie, Smit, Nathiana, Roy, Urmi, Lesker, Till Robin, Gálvez, Eric J.C., Helmecke, Julia, Basic, Marijana, Bleich, Andre, Goodman, Andrew L., Kalinke, Ulrich, Flavell, Richard A., Erhardt, Marc, Strowig, Till

Source: In Cell Host & Microbe 14 June 2017 21(6):682-694

CD14 Plays a Protective Role in Experimental Inflammatory Bowel Disease by Enhancing Intestinal Barrier Function

Authors: Buchheister, Stephanie, Buettner, Manuela, Basic, Marijana, Noack, Andreas, Breves, Gerhard, Buchen, Barbara, Keubler, Lydia M., Becker, Christoph, Bleich, André

Source: In The American Journal of Pathology May 2017 187(5):1106-1120

Loss of CD14 leads to disturbed epithelial-B cell crosstalk and impairment of the intestinal barrier after E. coli Nissle monoassociation

Authors: Basic, Marijana, Buettner, Manuela, Keubler, Lydia, Smoczek, Anna, Bruesch, Inga, Buchheister, Stephanie, Bleich, André

Source: Scientific reports. 8(1):1-14

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100103863222.0x000001&indx=1&recIds=ETOCvdc_100103863222.0x000001

Neonatally imprinted stromal cell subsets induce tolerogenic dendritic cells in mesenteric lymph nodes

Authors: Pezoldt, Joern, Pasztoi, Maria, Zou, Mangge, Wiechers, Carolin, Beckstette, Michael, Thierry, Guilhem, Vafadarnejad, Ehsan, Floess, Stefan, Arampatzi, Panagiota, Buettner, Manuela, Schweer, Janina, Fleissner, Diana, Vital, Marius, Pieper, Dietmar, Basic, Marijana, Dersch, Petra, Strowig, Till, Hornef, Mathias, Bleich, André, Bode, Ulrike, Pabst, Oliver, Bajénoff, Marc, Saliba, Antoine-Emmanuel, Huehn, Jochen

Source: Nature communications. 9(1):1-14

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183818087.0x000001&indx=1&recIds=ETOCvdc_100183818087.0x000001

Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition

Authors: Fulde, Marcus, Sommer, Felix, Chassaing, Benoit, Vorst, Kira, Dupont, Aline, Hensel, Michael, Basic, Marijana, Klopfleisch, Robert, Rosenstiel, Philip, Bleich, André, Bäckhed, Fredrik, Gewirtz, Andrew, Hornef, Mathias

Source: Nature. 560(7719):489-493

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100175727142.0x000001&indx=1&recIds=ETOCvdc_100175727142.0x000001