Two-Dimensional SEC-SEC-UV-MALS-dRI Workflow for Streamlined Analysis and Characterization of Biopharmaceuticals

Authors: Barrientos, Rodell C., Singh, Andrew N., Ukaegbu, Ophelia, Hemida, Mohamed, Wang, Heather, Ahmad, Imad Haidar, Hu, Hang, Dunn, Zachary D., Appiah-Amponsah, Emmanuel, Regalado, Erik L.

Source: ANALYTICAL CHEMISTRY -WASHINGTON DC-. 96(12):4960-4968

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Two-dimensional size exclusion reversed-phase liquid chromatography for quantitative analysis of L1 proteins in complex vaccine matrices

Authors: Arcinas, Arthur J. ^{a, ⁎}, Larson, Eli J. ^b, Buchhalter, Eric P. ^a, Dunn, Zachary D. ^b, Wang, Heather ^b, Singh, Andrew N. ^b, Barrientos, Rodell C. ^b, Ukaegbu, Ophelia ^b, Mukherjee, Malini ^a, Appiah-Amponsah, Emmanuel ^a, Regalado, Erik L. ^b

Source: In Journal of Chromatography A 10 May 2025 1748

What Do Students Think of Mobile Chemistry Games? Implications for Developing Mobile Learning Games in Chemistry Education

Authors: Garcia, Manuel B. (ORCID 0000-0003-2615-422X), Barrientos, Rodell C.

Source: International Journal of Game-Based Learning. 2023 13(1).

Peer Reviewed: Y

Page Count: 25

Descriptors: Chemistry, Science Instruction, Educational Games, Telecommunications, Handheld Devices, Student Attitudes, College Students, Experience, Competence, Student Experience, Self Esteem, Leisure Time, Foreign Countries

Geographic Terms: Philippines

Automated multicolumn screening workflow in ultra-high pressure hydrophilic interaction chromatography for streamlined method development of polar analytes

Authors: Hemida, Mohamed, Barrientos, Rodell C., Singh, Andrew N., Losacco, Gioacchino Luca, Wang, Heather, Guillarme, Davy, Larson, Eli, Xu, Wei, Appiah-Amponsah, Emmanuel, Regalado, Erik L.

Source: In Journal of Chromatography A 27 September 2024 1733

Improved assay development of pharmaceutical modalities using feedback-controlled liquid chromatography optimization

Authors: Naser Aldine, Fatima, Singh, Andrew N., Wang, Heather, Makey, Devin M., Barrientos, Rodell C., Wong, Michelle, Aggarwal, Pankaj, Regalado, Erik L., Ahmad, Imad A. Haidar

Source: In Journal of Chromatography A 10 May 2024 1722

Computer-assisted multifactorial method development for the streamlined separation and analysis of multicomponent mixtures in (Bio)pharmaceutical settings

Authors: Hemida, Mohamed, Haidar Ahmad, Imad A., Barrientos, Rodell C., Regalado, Erik L.

Source: In Analytica Chimica Acta 8 March 2024 1293

Automated Hydrophobic Interaction Chromatography Screening Combined with In Silico Optimization as a Framework for Nondenaturing Analysis and Purification of Biopharmaceuticals

Authors: Barrientos, Rodell C., Losacco, Gioacchino Luca, Azizi, Mohammadmehdi, Wang, Heather, Nguyen, Anh Nguyet, Shchurik, Vladimir, Singh, Andrew, Richardson, Douglas, Mangion, Ian, Guillarme, Davy

Source: Analytical chemistry. 94(49):17131-17141

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In Silico Method Development of Achiral and Chiral Tandem Column Reversed-phase Liquid Chromatography for Multicomponent Pharmaceutical Mixtures

Authors: Ahmad, Imad A. Haidar, Kiffer, Alaina, Barrientos, Rodell C., Losacco, Gioacchino Luca, Singh, Andrew, Shchurik, Vladimir, Wang, Heather, Mangion, Ian, Regalado, Erik L.

Source: Analytical chemistry. 94(9):4065-4071

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Process Analytical Technology for Real-Time Monitoring of Pharmaceutical Bioconjugation Reactions.

Authors: Ralbovsky, Nicole M., Dixit, Gunjan, Lomont, Justin P., Desai, Jay, Butu, Cristina, Saha-Shah, Anumita, Costello, Emily, Lukens, Janelle, Mazur, Michael, McHugh, Patrick M., Barrientos, Rodell C., Semple, Andrew, Hughes, Gregory J., Chmielowski, Rebecca, Wang, Sheng-Ching, Patel, Bhumit A., Smith, Joseph P.

Source: Organic Process Research & Development; 2/21/2025, Vol. 29 Issue 2, p353-362, 10p

Bivalent Conjugate Vaccine Induces Dual Immunogenic Response That Attenuates Heroin and Fentanyl Effects in Mice

Authors: Barrientos, Rodell C., Whalen, Connor, Torres, Oscar B., Sulima, Agnieszka, Bow, Eric W., Komla, Essie, Beck, Zoltan, Jacobson, Arthur E., Rice, Kenner C., Matyas, Gary R.

Source: Bioconjugate chemistry. 32(11):2295-2306

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Synthesis and immunological effects of C14-linked 4, 5-epoxymorphinan analogues as novel heroin vaccine haptensElectronic supplementary information (ESI) available. See DOI: 10.1039/d1cb00029b

Authors: Gutman, Eugene S., Irvin, Thomas C., Morgan, J. Brian, Barrientos, Rodell C., Torres, Oscar B., Beck, Zoltan, Matyas, Gary R., Jacobson, Arthur E., Rice, Kenner C.

Source: RSC chemical biology. 2(3):835-842

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Digitally Enabled Generic Analytical Framework Accelerating the Pace of Liquid Chromatography Method Development for Vaccine Adjuvant Formulations.

Authors: Hemida, Mohamed, Barrientos, Rodell C., Kinsey, Caleb, Kuster, Nathan, Bhavsar, Mayank, Beck, Armen G., Wang, Heather, Singh, Andrew, Aggarwal, Pankaj, Arcinas, Arthur, Mukherjee, Malini, Appiah-Amponsah, Emmanuel, Regalado, Erik L.

Source: ACS Pharmacology & Translational Science; 10/11/2024, Vol. 7 Issue 10, p3108-3118, 11p

Recent advances in the mass spectrometric analysis of glycosphingolipidome – A review

Authors: Barrientos, Rodell C., Zhang, Qibin

Source: In Analytica Chimica Acta 2 October 2020 1132:134-155

Synthesis of a deuterated 6‐AmHap internal standard for the determination of hapten density in a heroin vaccine drug product

Authors: Makarova, Mariia, Barrientos, Rodell C., Torres, Oscar B., Matyas, Gary R., Jacobson, Arthur E., Sulima, Agnieszka, Rice, Kenner C.

Source: Journal of labelled compounds & radiopharmaceuticals. 63(13):564-571

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Novel Vaccine That Blunts Fentanyl Effects and Sequesters Ultrapotent Fentanyl Analogues

Authors: Barrientos, Rodell C., Bow, Eric W., Whalen, Connor, Torres, Oscar B., Sulima, Agnieszka, Beck, Zoltan, Jacobson, Arthur E., Rice, Kenner C., Matyas, Gary R.

Source: Molecular pharmaceutics. 17(9):3447-3460

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"Build Your Own" ADC Mimics: Identification of Nontoxic Linker/Payload Mimics for HIC-Based DAR Determination, High-Throughput Optimization, and Continuous Flow Conjugation.

Authors: Emmert, Marion H., Bottecchia, Cecilia, Barrientos, Rodell C., Feng, Yinnian, Holland-Moritz, Daniel, Hughes, Gregory J., Lam, Yu-Hong, Regalado, Erik L., Ruccolo, Serge, Sun, Shuwen, Chmielowski, Rebecca, Yang, Cuixian, Lévesque, François, Raymond, Kelly, Haley, Monica

Source: Organic Process Research & Development; 8/16/2024, Vol. 28 Issue 8, p3326-3338, 13p

Differential Isotope Labeling by Permethylation and Reversed-Phase Liquid Chromatography—Mass Spectrometry for Relative Quantification of Intact Neutral Glycolipids in Mammalian Cells

Authors: Barrientos, Rodell C., Zhang, Qibin

Source: Analytical chemistry. 91(15):9673-9681

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Fragmentation Behavior and Gas-Phase Structures of Cationized Glycosphingolipids in Ozone-Induced Dissociation Mass Spectrometry

Authors: Barrientos, Rodell C., Zhang, Qibin

Source: Journal of the American Society for Mass Spectrometry. 30(9):1609-1620

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Dual‐Gradient Unified Chromatography: A New Paradigm for Versatility in Simultaneous Multicomponent Analysis

Authors: Losacco, Gioacchino Luca, Bennett, Raffeal, Ahmad, Imad A. Haidar, Barrientos, Rodell C., DaSilva, Jimmy O., Dong, Yuyang, Schuppe, Alexander W., Wang, Zeshu, Aiken, Sheenagh, Mangion, Ian, Aggarwal, Varinder K., Regalado, Erik L.

Source: Angewandte Chemie. 134(45)

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Isobaric Labeling of Intact Gangliosides toward Multiplexed LC—MS/MS-Based Quantitative Analysis

Authors: Barrientos, Rodell C., Zhang, Qibin

Source: Analytical chemistry. 90(4):2578-2586

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