Targeted CNS delivery using human MiniPromoters and demonstrated compatibility with adeno-associated viral vectors

Authors: de Leeuw, Charles N, Dyka, Frank M, Boye, Sanford L, Laprise, Stéphanie, Zhou, Michelle, Chou, Alice Y, Borretta, Lisa, McInerny, Simone C, Banks, Kathleen G, Portales-Casamar, Elodie, Swanson, Magdalena I, D'Souza, Cletus A, Boye, Shannon E, Jones, Steven JM, Holt, Robert A, Goldowitz, Daniel, Hauswirth, William W, Wasserman, Wyeth W, Simpson, Elizabeth M

Source: In Molecular Therapy - Methods & Clinical Development 2014 1

A regulatory toolbox of MiniPromoters to drive selective expression in the brain

Authors: Portales-Casamar, Elodie, Swanson, Douglas J., Liu, Li, de Leeuw, Charles N., Banks, Kathleen G., Sui, Shannan J. Ho, Fulton, Debra L., Ali, Johar, Amirabbasi, Mahsa, Arenillas, David J., Babyak, Nazar, Black, Sonia F., Bonaguro, Russell J., Brauer, Erich, Candido, Tara R., Castellarin, Mauro, Chen, Jing, Chen, Ying, Cheng, Jason C. Y., Chopra, Vik, Docking, T. Roderick, Dreolini, Lisa, D'Souza, Cletus A., Flynn, Erin K., Glenn, Randy, Hatakka, Kristi, Hearty, Taryn G., Imanian, Behzad, Jiang, Steven, Khorasan-zadeh, Shadi, Komljenovic, Ivana, Laprise, Stéphanie, Liao, Nancy Y., Lim, Jonathan S., Lithwick, Stuart, Liu, Flora, Liu, Jun, Lu, Meifen, McConechy, Melissa, McLeod, Andrea J., Milisavljevic, Marko, Mis, Jacek, O'Connor, Katie, Palma, Betty, Palmquist, Diana L., Schmouth, Jean-François, Swanson, Magdalena I., Tam, Bonny, Ticoll, Amy, Turner, Jenna L., Varhol, Richard, Vermeulen, Jenny, Watkins, Russell F., Wilson, Gary, Wong, Bibiana K. Y., Wong, Siaw H., Wong, Tony Y. T., Yang, George S., Ypsilanti, Athena R., Jones, Steven J. M., Holt, Robert A., Goldowitz, Daniel, Wasserman, Wyeth W., Simpson, Elizabeth M.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2010 Sep . 107(38), 16589-16594.

Access URL: https://www.jstor.org/stable/20779711

Retroposon compensatory mechanism hypothesis not supported: Zfa knockout mice are fertile

Authors: Banks, Kathleen G, Johnson, Kevin A, Lerner, Charles P, Mahaffey, Connie L, Bronson, Roderick T, Simpson, Elizabeth M

Source: In Genomics 2003 82(3):254-260

Targeting of >1.5 Mb of Human DNA into the Mouse X Chromosome Reveals Presence of cis-Acting Regulators of Epigenetic Silencing.

Authors: Yang, Christine¹, McLeod, Andrea J.², Cotton, Allison M.¹, de Leeuw, Charles N.², Laprise, Stéphanie², Banks, Kathleen G.², Simpson, Elizabeth M.^2,3, Brown, Carolyn J.¹, carolyn.brown@ubc.ca

Source: Genetics; Dec2012, Vol. 192 Issue 4, p1281-1293, 27p

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Non-coding-regulatory regions of human brain genes delineated by BAC knock-in mice.

Authors: Schmouth, Jean-François, Castellarin, Mauro, Laprise, Stéphanie, Banks, Kathleen G., Bonaguro, Russell J., McInerny, Simone C., Borretta, Lisa, Amirabbasi, Mahsa, Korecki, Andrea J., Portales-Casamar, Elodie, Wilson, Gary, Dreolini, Lisa, Jones, Steven J. M., Wasserman, Wyeth W., Goldowitz, Daniel, Robert A Holt, Simpson, Elizabeth M.

Source: BMC Biology; 2013, Vol. 11 Issue 1, p1-37, 37p

Subject Terms: NON-coding DNA, HUMAN genetics, GENOMES, GENE expression, NEUROSCIENCES

Caspase-7 Expanded Function and Intrinsic Expression Level Underlies Strain-Specific Brain Phenotype of Caspase-3-Null Mice.

Authors: Houde, Caroline¹, Banks, Kathleen G.², Coulombe, Nathalie³, Rasper, Dita³, Grimm, Erich³, Roy, Sophie^1,4, Simpson, Elizabeth M.², Nicholson, Donald W.^1,4 donald_nicholson@merck.com

Source: Journal of Neuroscience. 11/03/2004, Vol. 24 Issue 44, p9977-9984. 8p. 1 Color Photograph, 4 Diagrams, 3 Charts, 4 Graphs.

Subject Terms: *BRAIN diseases, *GENES, *ENZYMES, *APOPTOSIS, *DNA

Gaping lids, gp, a mutation on centromeric Chromosome 11 that causes defective eyelid development in mice.

Authors: Juriloff, Diana M., Harris, Muriel J., Banks, Kathleen G., Mah, Diana G.

Source: Mammalian Genome; Jun2000, Vol. 11 Issue 6, p440-447, 08p

Subject Terms: EYELIDS, ADNEXA oculi, GENES, MAMMALS, GENETIC mutation, GENETICS

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